메뉴 건너뛰기




Volumn 28, Issue 6, 1996, Pages 533-539

Abnormalities of brain structure and function in schizophrenia: Implications for aetiology and pathophysiology

Author keywords

Brain development; Brain imaging; Neuropathology; Obstetric complications; Schizophrenia

Indexed keywords

AUTOPSY; BRAIN DEVELOPMENT; BRAIN DYSFUNCTION; BRAIN FUNCTION; COGNITION; DISEASE SEVERITY; FAMILY STUDY; FRONTAL LOBE; GENETIC PREDISPOSITION; HEREDITY; HUMAN; IMAGING; NEUROPATHOLOGY; NEUROPSYCHOLOGY; OBSTETRICS; PATHOPHYSIOLOGY; PERINATAL MORBIDITY; PHENOTYPE; PRENATAL DISORDER; PRIORITY JOURNAL; REVIEW; RISK; SCHIZOPHRENIA; SYMPTOM; TEMPORAL LOBE; TWINS;

EID: 0030447824     PISSN: 07853890     EISSN: None     Source Type: Journal    
DOI: 10.3109/07853899608999117     Document Type: Review
Times cited : (57)

References (49)
  • 1
    • 84921009118 scopus 로고
    • Cerebral ventricular size and cognitive impairment in chronic schizophrenia
    • Johnstone EC, Crow TJ, Frith D, Husband J, Kreel L. Cerebral ventricular size and cognitive impairment in chronic schizophrenia. Lancet 1976; ii: 924-6.
    • (1976) Lancet , vol.2 , pp. 924-926
    • Johnstone, E.C.1    Crow, T.J.2    Frith, D.3    Husband, J.4    Kreel, L.5
  • 2
    • 0011264790 scopus 로고
    • The possible neurodevelopmental significance of structural imaging findings in schizophrenia
    • Mednick SA, Cannon TD, Barr CE, LaFosse J, eds. New York: Plenum Press
    • Cannon TD. The possible neurodevelopmental significance of structural imaging findings in schizophrenia. In: Mednick SA, Cannon TD, Barr CE, LaFosse J, eds. Developmental Neuropathology of Schizophrenia. New York: Plenum Press, 1991: 149-66.
    • (1991) Developmental Neuropathology of Schizophrenia , pp. 149-166
    • Cannon, T.D.1
  • 3
    • 0003155373 scopus 로고
    • The neuropathology of schizophrenia
    • Hirsch SR, Weinberger DR, eds. Cambridge, MA: Blackwell Science Ltd
    • Falkai P, Bogerts B. The neuropathology of schizophrenia. In: Hirsch SR, Weinberger DR, eds. Schizophrenia. Cambridge, MA: Blackwell Science Ltd, 1995: 275-92.
    • (1995) Schizophrenia , pp. 275-292
    • Falkai, P.1    Bogerts, B.2
  • 4
    • 0027288365 scopus 로고
    • Neuroimaging in schizophrenia research
    • Gur RE, Pearlson GD. Neuroimaging in schizophrenia research. Schizophr Bull 1993; 19: 337-53.
    • (1993) Schizophr Bull , vol.19 , pp. 337-353
    • Gur, R.E.1    Pearlson, G.D.2
  • 5
    • 0029881243 scopus 로고    scopus 로고
    • Regional cerebral blood flow in schizophrenia and the local circuit neurons hypothesis
    • Bachneff SA. Regional cerebral blood flow in schizophrenia and the local circuit neurons hypothesis. Schizophr Bull 1996; 22: 163-82.
    • (1996) Schizophr Bull , vol.22 , pp. 163-182
    • Bachneff, S.A.1
  • 6
    • 0026756067 scopus 로고
    • Left-lateralized temporal lobe abnormalities and their relationship to thought disorder: A computerized, quantitative MRI study
    • Shenton ME, Kikinis R, Jolesz RA, et al. Left-lateralized temporal lobe abnormalities and their relationship to thought disorder: a computerized, quantitative MRI study. N Engl J Med 1992; 327: 604-12.
    • (1992) N Engl J Med , vol.327 , pp. 604-612
    • Shenton, M.E.1    Kikinis, R.2    Jolesz, R.A.3
  • 7
    • 0028261615 scopus 로고
    • Structural brain abnormalities as indicators of vulnerability to schizophrenia
    • Cannon TD, Marco E. Structural brain abnormalities as indicators of vulnerability to schizophrenia. Schizophr Bull 1994; 20: 89-102.
    • (1994) Schizophr Bull , vol.20 , pp. 89-102
    • Cannon, T.D.1    Marco, E.2
  • 8
    • 0020073394 scopus 로고
    • Cerebral ventricular size in twins discordant for schizophrenia
    • Reveley AM, Reveley MA, Clifford CA, Murray RM. Cerebral ventricular size in twins discordant for schizophrenia. Lancet 1982; i: 540-1.
    • (1982) Lancet , vol.1 , pp. 540-541
    • Reveley, A.M.1    Reveley, M.A.2    Clifford, C.A.3    Murray, R.M.4
  • 10
    • 85035187303 scopus 로고    scopus 로고
    • Structural brain abnormalities in discordant offspring of schizophrenic mothers
    • in press
    • Eyler Zorrilla LT, Cannon TD, Kronenberg S, et al. Structural brain abnormalities in discordant offspring of schizophrenic mothers. Biol Psychiatry (in press).
    • Biol Psychiatry
    • Eyler Zorrilla, L.T.1    Cannon, T.D.2    Kronenberg, S.3
  • 12
    • 0022581021 scopus 로고
    • Physiologic dysfunction of dorsolateral prefrontal cortex in schizophrenia. I. Regional cerebral blood flow evidence
    • Weinberger DR, Berman KF, Zec RF. Physiologic dysfunction of dorsolateral prefrontal cortex in schizophrenia. I. Regional cerebral blood flow evidence. Arch Gen Psychiatry 1986; 43: 114-24.
    • (1986) Arch Gen Psychiatry , vol.43 , pp. 114-124
    • Weinberger, D.R.1    Berman, K.F.2    Zec, R.F.3
  • 13
    • 0025719203 scopus 로고
    • Altered modulation of prefrontal and subcortical brain activity in newly diagnosed schizophrenia and schizophreniform disorder: A regional cerebral blood flow study
    • Rubin P, Holm S, Friberg L, et al. Altered modulation of prefrontal and subcortical brain activity in newly diagnosed schizophrenia and schizophreniform disorder: a regional cerebral blood flow study. Arch Gen Psychiatry 1991; 48: 987-95.
    • (1991) Arch Gen Psychiatry , vol.48 , pp. 987-995
    • Rubin, P.1    Holm, S.2    Friberg, L.3
  • 16
    • 0027525952 scopus 로고
    • A theory of dopamine function and its role in cognitive deficits in schizophrenia
    • Cohen JD, Servan-Schreiber D. A theory of dopamine function and its role in cognitive deficits in schizophrenia. Schizophr Bull 1993; 19: 85-104.
    • (1993) Schizophr Bull , vol.19 , pp. 85-104
    • Cohen, J.D.1    Servan-Schreiber, D.2
  • 17
    • 0020078564 scopus 로고
    • Mental phenomena evoked by electrical stimulation of the human hippocampal formation and amygdala
    • Halgren E, Walter RD, Cherlow DG, Crandall PH. Mental phenomena evoked by electrical stimulation of the human hippocampal formation and amygdala. Ann Neurol 1982; 12: 129-44.
    • (1982) Ann Neurol , vol.12 , pp. 129-144
    • Halgren, E.1    Walter, R.D.2    Cherlow, D.G.3    Crandall, P.H.4
  • 18
    • 0025323015 scopus 로고
    • A 'mock up' of schizophrenia: Temporal lobe epilepsy and schizophrenia-like psychosis
    • Roberts GW, Done DJ, Bruton C, Crow TJ. A 'mock up' of schizophrenia: temporal lobe epilepsy and schizophrenia-like psychosis. Biol Psychiatry 1990; 28: 127-43.
    • (1990) Biol Psychiatry , vol.28 , pp. 127-143
    • Roberts, G.W.1    Done, D.J.2    Bruton, C.3    Crow, T.J.4
  • 19
    • 0025879236 scopus 로고
    • Neuropsychological function in schizophrenia: Selective impairment in memory and learning
    • Saykin AJ, Gur RC, Gur RE, et al. Neuropsychological function in schizophrenia: selective impairment in memory and learning. Arch Gen Psychiatry 1991; 48: 618-24.
    • (1991) Arch Gen Psychiatry , vol.48 , pp. 618-624
    • Saykin, A.J.1    Gur, R.C.2    Gur, R.E.3
  • 20
    • 0028144551 scopus 로고
    • Neuropsychological deficits in neuroleptic naive, first episode schizophrenic patients
    • Saykin AJ, Shtasel DL, Gur RE, et al. Neuropsychological deficits in neuroleptic naive, first episode schizophrenic patients. Arch Gen Psychiatry 1994; 51: 124-31.
    • (1994) Arch Gen Psychiatry , vol.51 , pp. 124-131
    • Saykin, A.J.1    Shtasel, D.L.2    Gur, R.E.3
  • 21
    • 0020636304 scopus 로고
    • Brain function in psychiatric disorders: I. Regional cerebral blood flow in medicated schizophrenics
    • Gur RE, Skolnick BE, Gur RC, et al. Brain function in psychiatric disorders: I. Regional cerebral blood flow in medicated schizophrenics. Arch Gen Psychiatry 1983; 40: 1250-4.
    • (1983) Arch Gen Psychiatry , vol.40 , pp. 1250-1254
    • Gur, R.E.1    Skolnick, B.E.2    Gur, R.C.3
  • 22
    • 0028009290 scopus 로고
    • Cerebral blood flow in schizophrenia: Effects of memory processing on regional activation
    • Gur RE, Jaggi J, Shtasel DL, Ragland JD, Gur RC. Cerebral blood flow in schizophrenia: effects of memory processing on regional activation. Biol Psychiatry 1994; 35: 3-15.
    • (1994) Biol Psychiatry , vol.35 , pp. 3-15
    • Gur, R.E.1    Jaggi, J.2    Shtasel, D.L.3    Ragland, J.D.4    Gur, R.C.5
  • 23
    • 0025644458 scopus 로고
    • Hypofrontal vs. hypo-sylvian blood flow in schizophrenia
    • Wood F, Flowers DL. Hypofrontal vs. hypo-sylvian blood flow in schizophrenia. Schizophr Bull 1990; 16: 413-24.
    • (1990) Schizophr Bull , vol.16 , pp. 413-424
    • Wood, F.1    Flowers, D.L.2
  • 24
    • 0026700588 scopus 로고
    • Toward a neuroanatomy of obsessive-compulsive disorder
    • Insel TR. Toward a neuroanatomy of obsessive-compulsive disorder. Arch Gen Psychiatry 1992; 49: 739-44.
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 739-744
    • Insel, T.R.1
  • 25
    • 0027216273 scopus 로고
    • The genetics of schizophrenia: A current genetic-epidemiologic perspective
    • Kendler KS, Diehl SR. The genetics of schizophrenia: a current genetic-epidemiologic perspective. Schizophr Bull 1993; 2: 261-85.
    • (1993) Schizophr Bull , vol.2 , pp. 261-285
    • Kendler, K.S.1    Diehl, S.R.2
  • 26
    • 0024368042 scopus 로고
    • Strategies for linkage studies of schizophrenia: Pedigrees, DNA markers, and statistical analyses
    • Diehl SR, Kendler KS. Strategies for linkage studies of schizophrenia: pedigrees, DNA markers, and statistical analyses. Schizophr Bull 1989; 15: 403-19.
    • (1989) Schizophr Bull , vol.15 , pp. 403-419
    • Diehl, S.R.1    Kendler, K.S.2
  • 27
    • 0025008255 scopus 로고
    • Measuring the inflation of the lod score due to its maximization over model parameter values in human linkage analysis
    • Weeks DE, Lehner T, Squires-Wheeler E, Kaufmann C, Ott J. Measuring the inflation of the lod score due to its maximization over model parameter values in human linkage analysis. Genet Epidemiol 1990; 7: 237-43.
    • (1990) Genet Epidemiol , vol.7 , pp. 237-243
    • Weeks, D.E.1    Lehner, T.2    Squires-Wheeler, E.3    Kaufmann, C.4    Ott, J.5
  • 28
    • 0014977449 scopus 로고
    • Psychoses in the offspring of schizophrenic monozygotic twins and their normal co-twins
    • Fisher M. Psychoses in the offspring of schizophrenic monozygotic twins and their normal co-twins. Br J Psychiatry 1971; 118: 43-52.
    • (1971) Br J Psychiatry , vol.118 , pp. 43-52
    • Fisher, M.1
  • 29
    • 0023600006 scopus 로고
    • Clinical genetics as clues to the 'real' genetics of schizophrenia
    • Gottesman II, McGuffin P, Farmer AE. Clinical genetics as clues to the 'real' genetics of schizophrenia. Schizophr Bull 1987; 13: 23-47.
    • (1987) Schizophr Bull , vol.13 , pp. 23-47
    • Gottesman, I.I.1    McGuffin, P.2    Farmer, A.E.3
  • 30
    • 0025037106 scopus 로고
    • Neuropsychological assessment of monozygotic twins discordant for schizophrenia
    • Goldberg TE, Ragland JD, Torrey EF, Gold JM. Neuropsychological assessment of monozygotic twins discordant for schizophrenia. Arch Gen Psychiatry 1990; 47: 1066-72.
    • (1990) Arch Gen Psychiatry , vol.47 , pp. 1066-1072
    • Goldberg, T.E.1    Ragland, J.D.2    Torrey, E.F.3    Gold, J.M.4
  • 32
    • 0027983532 scopus 로고
    • Neuropsychological functioning in siblings discordant for schizophrenia and healthy volunteers
    • Cannon TD, Eyler Zorrilla LT, Shtasel DL, et al. Neuropsychological functioning in siblings discordant for schizophrenia and healthy volunteers. Arch Gen Psychiatry 1994; 51: 651-61.
    • (1994) Arch Gen Psychiatry , vol.51 , pp. 651-661
    • Cannon, T.D.1    Eyler Zorrilla, L.T.2    Shtasel, D.L.3
  • 33
  • 35
    • 0027161815 scopus 로고
    • Developmental brain abnormalities in the offspring of schizophrenic mothers. I. Genetic and perinatal contributions
    • Cannon TD, Mednick SA, Parnas J, Schulsinger F, Praestholm J, Vestergaard A. Developmental brain abnormalities in the offspring of schizophrenic mothers. I. Genetic and perinatal contributions. Arch Gen Psychiatry 1993; 50: 551-64.
    • (1993) Arch Gen Psychiatry , vol.50 , pp. 551-564
    • Cannon, T.D.1    Mednick, S.A.2    Parnas, J.3    Schulsinger, F.4    Praestholm, J.5    Vestergaard, A.6
  • 36
    • 0025629940 scopus 로고
    • Reduction in temporal lobe size in siblings with schizophrenia: A magnetic resonance imaging study
    • Dauphinais ID, DeLisi LE, Crow TJ, et al. Reduction in temporal lobe size in siblings with schizophrenia: a magnetic resonance imaging study. Psychiatry Res 1990; 35: 137-47.
    • (1990) Psychiatry Res , vol.35 , pp. 137-147
    • Dauphinais, I.D.1    DeLisi, L.E.2    Crow, T.J.3
  • 37
    • 0026447204 scopus 로고
    • Regional cerebral blood flow in monozygotic twins discordant and concordant for schizophrenia
    • Berman KF, Torrey EF, Daniel DG, Weinberger DR. Regional cerebral blood flow in monozygotic twins discordant and concordant for schizophrenia. Arch Gen Psychiatry 1992; 49: 927-34.
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 927-934
    • Berman, K.F.1    Torrey, E.F.2    Daniel, D.G.3    Weinberger, D.R.4
  • 40
    • 0028223508 scopus 로고
    • Prenatal influenza infections and adult schizophrenia
    • Mednick SA, Huttunen MO, Machon RA. Prenatal influenza infections and adult schizophrenia. Schizophr Bull 1994; 20: 263-7.
    • (1994) Schizophr Bull , vol.20 , pp. 263-267
    • Mednick, S.A.1    Huttunen, M.O.2    Machon, R.A.3
  • 41
    • 0025614304 scopus 로고
    • Problems and pitfalls of the family history positive and negative dichotomy: Response to Dalen
    • Farmer A, McGuffin P, Gottesman II. Problems and pitfalls of the family history positive and negative dichotomy: response to Dalen. Schizophr Bull 1990; 16: 367-70.
    • (1990) Schizophr Bull , vol.16 , pp. 367-370
    • Farmer, A.1    McGuffin, P.2    Gottesman, I.I.3
  • 43
    • 0028297040 scopus 로고
    • Obstetric complications in histories of monozygotic twins discordant and concordant for schizophrenia
    • McNeil TF, Cantor-Grace E, Torrey EF, et al. Obstetric complications in histories of monozygotic twins discordant and concordant for schizophrenia. Acta Psychiatr Scand 1994; 89: 196-204.
    • (1994) Acta Psychiatr Scand , vol.89 , pp. 196-204
    • McNeil, T.F.1    Cantor-Grace, E.2    Torrey, E.F.3
  • 44
    • 85035188083 scopus 로고    scopus 로고
    • A prospective cohort study of genetic and perinatal influences in the etiology of schizophrenia
    • in review
    • Cannon TO, Hollister JM, Bearden C, Hadley T. A prospective cohort study of genetic and perinatal influences in the etiology of schizophrenia. Arch Gen Psychiatry (in review).
    • Arch Gen Psychiatry
    • Cannon, T.O.1    Hollister, J.M.2    Bearden, C.3    Hadley, T.4
  • 45
    • 0027393825 scopus 로고
    • Hippocampal dysgenesis in mutant mouse and schizophrenic man: Is there a relationship
    • Scheibel AB, Conrad AS. Hippocampal dysgenesis in mutant mouse and schizophrenic man: is there a relationship. Schizophr Bull 1993; 19: 22-33.
    • (1993) Schizophr Bull , vol.19 , pp. 22-33
    • Scheibel, A.B.1    Conrad, A.S.2
  • 46
    • 0028277546 scopus 로고
    • Elderly patients with schizophrenia exhibit infrequent neurodegenerative lesions
    • Arnold SE, Franz BR, Trojanowski JQ. Elderly patients with schizophrenia exhibit infrequent neurodegenerative lesions. Neurobiol Aging 1994; 15: 299-303.
    • (1994) Neurobiol Aging , vol.15 , pp. 299-303
    • Arnold, S.E.1    Franz, B.R.2    Trojanowski, J.Q.3
  • 47
    • 0023520175 scopus 로고
    • High-risk research in schizophrenia: A summary of what has been learned
    • Erlenmeyer-Kimling L, Cornblatt B. High-risk research in schizophrenia: a summary of what has been learned. J Psychiatr Res 1987; 21: 401-11.
    • (1987) J Psychiatr Res , vol.21 , pp. 401-411
    • Erlenmeyer-Kimling, L.1    Cornblatt, B.2
  • 48
    • 0028171814 scopus 로고
    • Child developmental risk factors for adult schizophrenia in the British 1946 birth cohort
    • Jones P, Rodgers B, Murray R, Marmot M. Child developmental risk factors for adult schizophrenia in the British 1946 birth cohort. Lancet 1994; 344: 1398-402.
    • (1994) Lancet , vol.344 , pp. 1398-1402
    • Jones, P.1    Rodgers, B.2    Murray, R.3    Marmot, M.4
  • 49
    • 85035182896 scopus 로고    scopus 로고
    • A prospective cohort study of childhood cognitive deficits as precursors of schizophrenia
    • in review
    • Cannon TD, Bearden C, Hollister JM, Hadley T. A prospective cohort study of childhood cognitive deficits as precursors of schizophrenia. Arch Gen Psychiatry (in review).
    • Arch Gen Psychiatry
    • Cannon, T.D.1    Bearden, C.2    Hollister, J.M.3    Hadley, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.