Inflammatory aspects of experimental aneurysms: Effect of methylprednisolone and cyclosporine

Annals of the New York Academy of Sciences

Volumn 800, Issue , 1996, Pages 74-88

  Dobrin, Philip B ^a,b   Baumgartner, Norbert ^c   Anidjar, Samy ^c   Chejfec, Gregorio ^c   Mrkvicka, Robert ^c  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; CYCLOSPORIN; ELASTASE; ELASTIN; FIBRILLIN; IMMUNOSUPPRESSIVE AGENT; METHYLPREDNISOLONE; PLASMIN; THIOGLYCOLIC ACID;

ADVENTITIA; ANEURYSM; ANEURYSM RUPTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ANEURYSM; ARTERY WALL; ARTICLE; CONNECTIVE TISSUE; CONTROLLED STUDY; HELPER CELL; INFLAMMATION; INFLAMMATORY CELL; LYMPHOCYTE; MACROPHAGE; MARFAN SYNDROME; MONOCYTE; NEUTROPHIL; NONHUMAN; RAT; SUPPRESSOR CELL; THYMOCYTE; VASODILATATION;

ANIMALIA;

EID: 0030447665     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1996.tb33300.x     Document Type: Article

References (39)

1. SUMNER, D. S., D. E. HOKANSON & D. E. STRANDNESS, JR. 1970. Stress-strain characteristics and collagen-elastin content of abdominal aortic aneurysms. Surg. Gynecol. Obstet. 147: 211-214.
2. SAKALIHASAN, N., A. HEYERES, B. V. NUSGENS, et al. 1993. Modifications of the extracellular matrix of aneurysmal abdominal aorta as a function of their size. Eur. J. Vasc. Surg. 7: 633-637.
3. BAXTER, B. T., V. A. DAVIS, D. J. MINION, et al. 1994. Abdominal aortic aneurysms are associated with altered matrix proteins of the nonaneurysmal aortic segment. J. Vasc. Surg. 19: 797-803.
4. HE, C. M. & M. R. ROACH. 1994. The composition and mechanical properties of abdominal aortic aneurysms. J. Vasc. Surg. 20: 6-13.
5. WHITE, J. V., K. HAAS, S. PHILLIPS, et al. 1993. Adventitial elastolysis is a primary event in aneurysm formation. J. Vasc. Surg. 17: 371-381.
6. DOBRIN, P. B., T. H. SCHWARCZ & W. H. BAKER. 1988. Mechanisms of arterial and aneurysmal tortuosity. Surgery 104: 568-571.
7. DOBRIN, P. B., T. H. SCHWARCZ & R. MRKVICKA. 1990. Longitudinal retractive force in pressurized dog and human arteries. J. Surg. Res. 48: 116-120.
8. DOBRIN, P. B., W. H. BAKER & W. C. GLEY. 1984. Elastolytic and collagenolytic studies of arteries. Implications for the mechanical properties of aneurysms. Arch. Surg. 119: 405-409.
9. TILSON, M. D., J. ELEFTERIADES & C. BROPHY. 1990. Tensile strength and collagen in abdominal aortic aneurysm disease. In The Cause and Management of Aneurysms. R. M. Greenhalgh & J. A. Mannick, Eds.: 90-104. W. B. Saunders. Philadelphia, PA.
10. DOBRIN, P. B. & R. MRKVICKA. 1994. Failure of elastin or collagen as possible critical connective tissue alterations underlying aneurysmal dilatation. Cardiovasc. Surg. 2: 484-488.
11. RIZZO, R. J., W. J. MCCARTHY, S. N. DIXIT, et al. 1989. Collagen types and matrix protein content in human abdominal aortic aneurysms. J. Vasc. Surg. 10: 365-373.
12. KOCH, A. E., G. K. HAINES, R. J. RIZZO, et al. 1990. Human abdominal aortic aneurysms: Immunophenotypic analysis suggesting an immune-mediated response. Am. J. Pathol. 137: 1199-1213.
13. BROPHY, C. M., J. M. REILLY, G. J. WALKER-SMITH, et al. 1991. The role of inflammation in nonspecific abdominal aortic aneurysm disease. Ann. Vasc. Surg. 5: 229-233.
14. ANIDJAR, S., J. L. SALZMANN, D. GENTRIC, et al. 1990. Elastase-induced experimental aneurysms in rats. Circulation 82: 973-981.
15. HSU, S. M. & L. RAINE. 1984. The use of avidin-biotin-peroxidase complex (ABC) in diagnostic and research pathology. In Advances in Immunohistochemistry. R. A. Lellis, Ed: 31-42. Masson. New York.
16. ANIDJAR, S., P. B. DOBRIN, M. EICHORST, et al. 1992. Correlation of inflammatory infiltrate with the enlargement of experimental aortic aneurysms. J. Vasc. Surg. 16: 139-147.
17. SENIOR, R. M., N. L. CONNOLLY, J. D. CURY, et al. 1989. Elastin degradation by human alveolar macrophages: A prominent role of metalloproteinase activity. Am. Rev. Respir. Dis. 139: 1251-1256.
18. WERB, Z., M. J. BANDA & P. A. JONES. 1980. Degradation of connective tissue matrices by macrophages. III. Morphological and biochemical studies on extracellular, pericellular, and intracellular events in matrix proteolysis by macrophages in culture. J. Exp. Med. 152: 1537-1553.
19. NEWMAN, K. M., J. JEAN-CLAUDE, H. LI, et al. 1994. Cytokines that activate proteoly-sis are increased in abdominal aortic aneurysms. Circulation 90(Part 2): II224-II227.
20. NEWMAN, K. M., J. JEAN-CLAUDE, H. LI, et al. 1994. Cellular localization of matrix metalloproteinases in the abdominal aortic aneurysm wall. J. Vasc. Surg. 20: 814-820.
21. HALPERN, V. J., G. B. NOCKMAN, R. H. GANDHI, et al. 1994. The elastase infusion model of experimental aortic aneurysms: Synchrony of induction of endogenous proteinases with matrix destruction and inflammatory cell responses. J. Vasc. Surg. 20: 51-60.
22. RICCI, M. A., G. STRINDBERG, J. M. SLAIBY, et al. Anti-CD18 monoclonal antibody slows experimental aortic aneurysm expansion. J. Vasc. Surg. In press.
23. BUSUTTIL, R. W., A. M. ABOU-ZAMZAM & H. L. MACHLEDER. 1980. Collagenase activity of the human aorta: Comparison of patients with and without abdominal aortic aneurysms. Arch. Surg. 115: 1373-1378.
24. BUSUTTIL, R. W., R. HEINRICH & A. FLESHER. 1982. Elastase activity: The role of elastase in aortic aneurysm formation. J. Surg. Res. 32: 214-217.
25. CANNON, D. J. & R. READ. 1982. Blood elastolytic activity in patients with aortic aneurysm. Ann. Thorac. Surg. 34: 10-15.
26. BROWN, S. L., B. BLADESTROM & R. W. BUSUTTIL. 1985. A new serum proteolytic enzyme in aneurysm pathogenesis. J. Vasc. Surg. 2: 393-399.
27. COHEN, J. R., C. MANDELL, I. MARGOLIS, et al. 1987. Altered aortic protease and antiprotease activity in patients with ruptured abdominal aortic aneurysms. Surg. Gynecol. Obstet. 164: 355-358.
28. DUBICK, M. A., G. C. HUNTER, E. PEREZ-LIZANO, et al. 1988. Assessment of the role of pancreatic proteases in human abdominal aortic aneurysms and occlusive disease. Clin. Chim. Acta. 177: 1-10.
29. HERON, G. S., E. UNEMORI, M. WONG, et al. 1991. Connective tissue proteases and inhibitors in abdominal aortic aneurysms. Involvement of the vasa vasorum in the pathogenesis of aortic aneurysms. Arterioscler. Thromb. 11: 1667-1677.
30. CRONENWETT, J., T. MURPHY, G. ZELENOCK, et al. 1985. Actuarial analysis of variables associated with rupture of small abdominal aortic aneurysms. Surgery 98: 472-483.
31. ICHIKAWA, Y., H. NONOMIYA, H. KOGATT, et al. 1992. Erythromycin reduces neutrophils and neutrophil-derived elastolytic-like activity in lower respiratory tract of bronchiolitis patients. Am. Rev. Respir. Dis. 146: 196-203.
32. KUCICH, U., P. CHRISTNER, M. LIPPMANN, et al. 1985. Utilization of peroxidase-antiperoxidase complex, an enzyme-linked immunosorbent assay of elastin-derived peptides in human plasma. Am. Rev. Respir. Dis. 131: 709-713.
33. COHEN, J. R., C. MANDELL, I. MARGOLIS, et al. 1987. Altered aortic protease and antiprotease activity in patients with ruptured abdominal aortic aneurysms. Surg. Gynecol. Obstet. 164: 355-358.
34. 1-antitrypsin deficiency: Etiologic implications. J. Vasc. Surg. 17: 420-424.
35. PARANJPE, M., L. ENGEL, N. YOUNG, et al. 1980. Activation of human breast carcinoma collagenase through plasminogen activator. Life Sci. 26: 1223-1231.
36. MURPHY, G., R. WARD, J. GAQVRILOVIC, et al. 1992. Physiological mechanisms for metalloproteinase activation. Matrix (Suppl. 1): 224-230.
37. TROMHOLT, N., S. S. J. JORGENSEN, B. HESSE, et al. 1993. In vivo demonstration of focal fibrinolytic activity in abdominal aortic aneurysms. Eur. J. Vasc. Surg. 7: 675-679.
38. REILLY, J. M., G. A. SICARD & C. L. LUCORE. 1994. Abnormal expression of plasminogen activators in aortic aneurysmal and occlusive disease. Surgery 119: 865-872.
39. JEAN-CLAUDE, J., K. M. NEWMAN, K. H. LI, et al. 1994. Possible key role for plasmin in the pathogenesis of abdominal aortic aneurysms. Surgery 116: 472-478.