Molecular modelling study of the binding of inhibitors of aromatase to the cytochrome P-450 heme

Drug Design and Discovery

Volumn 14, Issue 2, 1996, Pages 91-102

  Ahmed, Sabbir ^a   Davis, Paul J ^a   Owen, Caroline P ^a  

^a UNIVERSITY OF BRIGHTON   (United Kingdom)

Author keywords

Aromatase; Cytochrome P 450; Inhibitors; Molecular modelling; Substrate heme complex

Indexed keywords

AMINOGLUTETHIMIDE DERIVATIVE; ANDROSTENEDIONE; AROMATASE INHIBITOR; CYTOCHROME P450; FADROZOLE; HEME;

ARTICLE; BINDING SITE; CONTROLLED STUDY; ENANTIOMER; MOLECULAR MODEL; STRUCTURE ACTIVITY RELATION;

AMINOGLUTETHIMIDE; AROMATASE; AROMATASE INHIBITORS; BINDING SITES; COMPUTER SIMULATION; FADROZOLE; HEME; LIGANDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PYRIDINES; STEREOISOMERISM; STEROIDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030447388     PISSN: 10559612     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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