Does lead provoke the peroxidation process in rat brain synaptosomes?

Molecular and Chemical Neuropathology

Volumn 29, Issue 2-3, 1996, Pages 127-139

  Dabrowska Bouta, Beata ^a   Struzyńska, Lidia ^a   RafaŁowska, Urszula ^a  

^a MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

Author keywords

brain; Lead; liver; peroxidation; synaptosomes

Indexed keywords

FREE RADICAL; LEAD ACETATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN EDEMA; BRAIN HEMORRHAGE; BRAIN MICROSOME; BRAIN SYNAPTOSOME; CEREBRAL PALSY; CONTROLLED STUDY; LEAD POISONING; LIVER INJURY; MALE; NERVE ENDING; NONHUMAN; PEROXIDATION; PRIORITY JOURNAL; RAT;

EID: 0030446874     PISSN: 10447393     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02814997     Document Type: Article

References (8)

1. Andesirk G. (1990) Effects of heavy metals on neuronal calcium channels, in Focus on Biological Effects of Heavy Metals (Foulkes E. C., ed.), CRC, Boca Raton, FL, pp. 1-18.
2. Andesirk G. (1993) Electrophysiology of lead intoxication: Effects on voltage-sensitive ion channels. NeuroToxicology 14 (2-3), 137-148.
3. Asakawa T. and Matsushita S. (1980) Coloring conditions of thiobarbituric acid test for detecting lipid hydroperoxidas. Lipids 15, 137-140.
4. Bligh E. G. and Dyer W. J. (1959) A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37, 911-917.
5. Booth R. F. G. and Clark J. B. (1978) A rapid method for the preparation of relatively pure, metabolically competent synaptosomes from rat brain. Biochem. J. 176, 365-370.
6. Bradbury M. W. B. and Deane R. (1993) Permeability of the blood-brain barrier to lead. NeuroToxicoIogy 14 (2-3), 131-136.
7. Bucher J. R., Tien M., and Aust S. D. (1983) The requirement for ferric in the initiation of lipid peroxidation by chelated ferrous iron. Biochem. Biophys. Res.f Commun. 111, 777-784.
8. Da̧browska-Bouta B., Struzyńska L., and Rafatowska U. (1994) Peroxidation in the synaptosomes under lead-toxicity conditions. 17th Annual Meeting of ENA, Vienna.