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Volumn 21, Issue 2, 1996, Pages 111-120

Amino acid metabolism during batch culture of a murine hybridoma, AFP-27

Author keywords

Batch culture; Enriched media; Extracellular and intracellular amino acids; Glucose; Hybridoma; Lactate

Indexed keywords


EID: 0030446530     PISSN: 09209069     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02215661     Document Type: Article
Times cited : (3)

References (25)
  • 1
    • 27844434068 scopus 로고
    • Animal cell culture, in International patent no. WO 87/00195
    • Birch JR and Boraston RC (1987) Animal cell culture, in International patent no. WO 87/00195.
    • (1987)
    • Birch, J.R.1    Boraston, R.C.2
  • 2
    • 0027909376 scopus 로고
    • A three-phase pattern in growth, monoclonal antibody production and metabolite exchange in a hybridoma bioreactor culture
    • Bushell ME, Bell SL, Scott MF, Snell K, Spier RE, Wardell JN and Sanders PG (1993) A three-phase pattern in growth, monoclonal antibody production and metabolite exchange in a hybridoma bioreactor culture. Biotechnol Bioeng 42: 133-139.
    • (1993) Biotechnol Bioeng , vol.42 , pp. 133-139
    • Bushell, M.E.1    Bell, S.L.2    Scott, M.F.3    Snell, K.4    Spier, R.E.5    Wardell, J.N.6    Sanders, P.G.7
  • 3
    • 0026066794 scopus 로고
    • Molecular mechanisms involved in the regulation of amino acid transport
    • Cheeseman CI (1991) Molecular mechanisms involved in the regulation of amino acid transport Prog Biophys Molec Biol 55: 71-84.
    • (1991) Prog Biophys Molec Biol , vol.55 , pp. 71-84
    • Cheeseman, C.I.1
  • 4
    • 0021963336 scopus 로고
    • On the strategy of kinetic discrimination of amino acid transport systems
    • Christensen HN (1985) On the strategy of kinetic discrimination of amino acid transport systems. J. Membrane 84: 97-103.
    • (1985) J. Membrane , vol.84 , pp. 97-103
    • Christensen, H.N.1
  • 5
    • 27844602869 scopus 로고
    • eRDF medium enhances antibody production of IgG and IgM secreting hybridomas
    • (Proceedings of the 5th International Meeting of the Japanse Association for Animal Cell Technology, Nov. 30 - Dec. 4, Omiya, Japan), Kaminogawa S, Ametani A and Hachimura S (eds), Kluwer, Dordrecht
    • Chua F, OH SKW, Yap M and Teo WK (1992) eRDF medium enhances antibody production of IgG and IgM secreting hybridomas. In Animal Cell Technology: Basic and Applied Aspects, Vol. 5, pp. 391-396 (Proceedings of the 5th International Meeting of the Japanse Association for Animal Cell Technology, Nov. 30 - Dec. 4, Omiya, Japan), Kaminogawa S, Ametani A and Hachimura S (eds), Kluwer, Dordrecht.
    • (1992) Animal Cell Technology: Basic and Applied Aspects , vol.5 , pp. 391-396
    • Chua, F.1    Oh, S.K.W.2    Yap, M.3    Teo, W.K.4
  • 6
    • 0025438136 scopus 로고
    • Cell volume measurement as an estimation of mammalian cell biomass
    • Frame KK and Hu W-S (1990) Cell volume measurement as an estimation of mammalian cell biomass. Biotechnol Bioeng 36: 191-197.
    • (1990) Biotechnol Bioeng , vol.36 , pp. 191-197
    • Frame, K.K.1    Hu, W.-S.2
  • 7
    • 0026218150 scopus 로고
    • Hybridoma growth and monoclonal antibody production in iron-rich protein-free medium: Effect of nutrient concentration
    • Franek F and Dolnikova J (1991) Hybridoma growth and monoclonal antibody production in iron-rich protein-free medium: effect of nutrient concentration. Cytotechnology 7: 33-38 : 1041-1048.
    • (1991) Cytotechnology , vol.7 , pp. 33-38
    • Franek, F.1    Dolnikova, J.2
  • 8
    • 0002548987 scopus 로고
    • The energetics of glutaminolysis - A theoretical evaluation
    • Spier RE, Griffiths JB and Maignier B (eds.), Butterworth-Heinemann, Oxford
    • Haggstrom L (1991) The energetics of glutaminolysis - a theoretical evaluation. In Production of biologicals from animal cells in culture. Spier RE, Griffiths JB and Maignier B (eds.), Butterworth-Heinemann, Oxford pp. 79-81.
    • (1991) Production of Biologicals from Animal Cells in Culture , pp. 79-81
    • Haggstrom, L.1
  • 9
    • 0025701084 scopus 로고
    • Balanced nutrient fortification enables high-density hybridoma cell culture in batch culture
    • Jo E-C, Park H-J, Park J-M and Kim K-H (1990) Balanced nutrient fortification enables high-density hybridoma cell culture in batch culture Biotechnol Bioeng 36 717-722.
    • (1990) Biotechnol Bioeng , vol.36 , pp. 717-722
    • Jo, E.-C.1    Park, H.-J.2    Park, J.-M.3    Kim, K.-H.4
  • 10
    • 84984086633 scopus 로고
    • The cultivation of animal cells at controlled dissolved oxygen partial pressure
    • Kilburn DG and Webb C (1968) The cultivation of animal cells at controlled dissolved oxygen partial pressure. Biotechnol Bioeng 10: 801-814.
    • (1968) Biotechnol Bioeng , vol.10 , pp. 801-814
    • Kilburn, D.G.1    Webb, C.2
  • 12
    • 0026484670 scopus 로고
    • Glutamine-limited fed-batch culture reduces the overflow metabolism of amino acids in myeloma cells
    • Ljunggren J and Haggstrom L (1992) Glutamine-limited fed-batch culture reduces the overflow metabolism of amino acids in myeloma cells. Cytotechnology 8(1): 45-56.
    • (1992) Cytotechnology , vol.8 , Issue.1 , pp. 45-56
    • Ljunggren, J.1    Haggstrom, L.2
  • 13
    • 0011210335 scopus 로고
    • Strategies to extend the longetivity of hybridomas in culture and promote yield of monoclonal antibodies
    • Luan YT, Mutharasan R and Magee WE (1987) Strategies to extend the longetivity of hybridomas in culture and promote yield of monoclonal antibodies. Biotechnol Letts 9(10): 691-696.
    • (1987) Biotechnol Letts , vol.9 , Issue.10 , pp. 691-696
    • Luan, Y.T.1    Mutharasan, R.2    Magee, W.E.3
  • 14
    • 27844557879 scopus 로고
    • Fed-batch propagation of mouse hybridoma and human lymphoblastoid cell lines
    • Kaminogawa S, Ametani A and Hachimura S (eds.)
    • Marquis CP, Barford JP and Harbour C (1993a) Fed-batch propagation of mouse hybridoma and human lymphoblastoid cell lines. In Animal Cell Technology : Basic and Applied Aspects: Vol. 5, Kaminogawa S, Ametani A and Hachimura S (eds.), pp. 425-431.
    • (1993) Animal Cell Technology : Basic and Applied Aspects , vol.5 , pp. 425-431
    • Marquis, C.P.1    Barford, J.P.2    Harbour, C.3
  • 15
    • 0027130125 scopus 로고
    • Evaluation of the batch kinetics of the amino acid metabolism of a mouse hybridoma and human lymphoblastoid cell line using a pre-column FDNDEA derivitisation, HPLC technique
    • Marquis CP, Barford JP, Harbour C and Nobbs D (1993b) Evaluation of the batch kinetics of the amino acid metabolism of a mouse hybridoma and human lymphoblastoid cell line using a pre-column FDNDEA derivitisation, HPLC technique. Biotechnol Techn 7(11): 799-804.
    • (1993) Biotechnol Techn , vol.7 , Issue.11 , pp. 799-804
    • Marquis, C.P.1    Barford, J.P.2    Harbour, C.3    Nobbs, D.4
  • 16
    • 27844538351 scopus 로고
    • Specific productivity of antibody producing cells in batch culture
    • submitted for publication
    • Marquis CP, Barford JP, Harbour C and Fletcher A (1995a) Specific productivity of antibody producing cells in batch culture. J Biotechnol (submitted for publication).
    • (1995) J Biotechnol
    • Marquis, C.P.1    Barford, J.P.2    Harbour, C.3    Fletcher, A.4
  • 17
    • 0030446771 scopus 로고    scopus 로고
    • Carbohydrate and amino acid metabolism during batch culture of a human kymphoblastoid cell line, BTSN6
    • Marquis CP, Barford JP, Harbour C and Fletcher A (1996) Carbohydrate and amino acid metabolism during batch culture of a human kymphoblastoid cell line, BTSN6. Cytotechnology (see this issue).
    • (1996) Cytotechnology , Issue.THIS ISSUE
    • Marquis, C.P.1    Barford, J.P.2    Harbour, C.3    Fletcher, A.4
  • 18
    • 0028765762 scopus 로고
    • Induction of apoptosis in nutrient-deprived cultures of hybridoma and myeloma cell
    • Mercille S and Massie B (1994) Induction of apoptosis in nutrient-deprived cultures of hybridoma and myeloma cell. Biotechnol Bioeng 44: 1140-1154.
    • (1994) Biotechnol Bioeng , vol.44 , pp. 1140-1154
    • Mercille, S.1    Massie, B.2
  • 19
    • 0024483833 scopus 로고
    • Serum-free media used for cultivation of hybridomas
    • Alan R Liss Inc. new York
    • Murakami H (1989) Serum-free media used for cultivation of hybridomas in: Monoclonal antibodies : production and application, Alan R Liss Inc. new York, pp. 107-141.
    • (1989) Monoclonal Antibodies : Production and Application , pp. 107-141
    • Murakami, H.1
  • 20
    • 0025514467 scopus 로고
    • Effects of dissolved oxygen on hybridoma cell growth metabolism and antibody production kinetics in continuous culture
    • Ozturk SS and Palsson BO (1990) Effects of dissolved oxygen on hybridoma cell growth metabolism and antibody production kinetics in continuous culture. Biotechnol Prog 6: 437-446.
    • (1990) Biotechnol Prog , vol.6 , pp. 437-446
    • Ozturk, S.S.1    Palsson, B.O.2
  • 21
    • 0023870346 scopus 로고
    • Glucose and glutamine metabolism in human peripheral lymphocytes
    • Salleh M and Ardawi M (1988) Glucose and glutamine metabolism in human peripheral lymphocytes. Metabolism 37(1): 99-103.
    • (1988) Metabolism , vol.37 , Issue.1 , pp. 99-103
    • Salleh, M.1    Ardawi, M.2
  • 22
    • 0019796746 scopus 로고
    • Neutral amino acid transport systems in Chinese hamster ovary cells
    • Shotwell MA, Jayma DW, Kilberg MS and Oxender DL (1981) Neutral amino acid transport systems in Chinese hamster ovary cells. J Biol Chem 256(11): 5422-5427.
    • (1981) J Biol Chem , vol.256 , Issue.11 , pp. 5422-5427
    • Shotwell, M.A.1    Jayma, D.W.2    Kilberg, M.S.3    Oxender, D.L.4
  • 23
    • 0027033717 scopus 로고
    • Monitoring hybridoma metabolism in continuous suspension culture at the intracellular level
    • Schmid G and Keller T (1992) Monitoring hybridoma metabolism in continuous suspension culture at the intracellular level. Cytotechnology 9(1-3): 217-229.
    • (1992) Cytotechnology , vol.9 , Issue.1-3 , pp. 217-229
    • Schmid, G.1    Keller, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.