Molecular cytogenetic characterization and physical mapping of 12q13-15 amplification in human cancers

Genes Chromosomes and Cancer

Volumn 17, Issue 4, 1996, Pages 205-214

  Elkahloun, Abdel G ^a   Bittner, Michael ^a   Hoskins, Kent ^b   Gemmill, Robert ^c   Meltzer, Paul S ^a,d  

^a NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF DENVER   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE;

ARTICLE; BRAIN TUMOR; CANCER; CENTROMERE; CHROMOSOME 12Q; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE MAPPING; GENETIC ANALYSIS; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL; SARCOMA; SEQUENCE ANALYSIS; SOUTHERN BLOTTING; TELOMERE; YEAST ARTIFICIAL CHROMOSOME;

BASE SEQUENCE; BLOTTING, SOUTHERN; CHROMOSOMES, ARTIFICIAL, YEAST; CHROMOSOMES, HUMAN, PAIR 12; GENE AMPLIFICATION; HISTIOCYTOMA, BENIGN FIBROUS; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MOLECULAR SEQUENCE DATA; NEUROBLASTOMA; RHABDOMYOSARCOMA; TUMOR CELLS, CULTURED;

EID: 0030446485     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2264(199612)17:4<205::AID-GCC2>3.0.CO;2-7     Document Type: Article

References (31)

1. Albertsen HM, Abderrahim H, Cann HM, Dausset J, Le Paslier D, Cohen D (1990) Construction and characterization of a yeast artificial chromosome library containing seven haploid human genome equivalents. Proc Natl Acad Sci USA 87:4256-4260.
2. Ashar HR, Fejzo MS, Tkachenko A, Zhou X, Fletcher JA, Weremowicz S, Morton CC, Chada K (1995) Disruption of the architectural factor HMGI-C: DNA-binding AT hook motifs fused in lipomas to distinct transcriptional regulatory domains. Cell 82:57-65.
3. Carle GF, Olson MV (1985) An electrophoretic karyotype for yeast. Proc Natl Acad Sci USA 82:3756-3760.
4. Cowell JK, Miller OJ (1983) Occurrence and evolution of homogeneously staining regions may be due to breakage-fusion-bridge cycles following telomere loss. Chromosoma 88:216-221.
5. Dong JT, Lamb PW, Rinker-Schaeffer CW, Vukanovic J, Ichikawa T, Isaacs JT, Barrett JC (1995) KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2. Science 268:884-886.
6. el Deiry W, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW, Vogelstein B (1993) WAF1, a potential mediator of p53 tumor suppression. Cell 75:817-825.
7. Elkahloun A, Vernet C, Jouanolle AM, Boretto J, Mauvieux V, Le Gall JY, David V, Pontarotti P (1992) A continuous restriction map from HLA-E to HLA-F. Structural comparison between different HLA-A haplotypes. Immunogenetics 35:183-189.
8. Elkahloun AG, Meltzer PS, Guan XY, McNinch JS, Trent JM, de Jong PJ (1996) Isolation of a cosmid sublibrary for a region of chromosome 12 frequently amplified in human cancers using a complex chromosome microdissection probe. Genomics 31:343-347.
9. Forus A, Florenes VA, Maelandsmo GM, Meltzer PS, Fodstad O, Myklebost O (1993) Mapping of amplification units in the q13-14 region of chromosome 12 in human sarcomas: Some amplica do not include MDM2. Cell Growth Diff 4:1065-1070.
10. Green ED, Olson MV (1990) Systematic screening of yeast artificial-chromosome libraries by use of the polymerase chain reaction. Proc Natl Acad Sci USA 87:1213-1217.
11. Guan XY, Meltzer PS, Cao J, Trent JM (1992) Rapid generation of region-specific genomic clones by chromosome microdissection: Isolation of DNA from a region frequently deleted in malignant melanoma. Genomics 14:680-684.
12. Guan XY, Meltzer PS, Dalton WS, Trent JM (1994) Identification of cryptic sites of DNA sequence amplification in human breast cancer by chromosome microdissection. Nature Genet 8:155-161.
13. Heighway J, Mitchell EL, Jones D, White GR, Santibanez Koref MF (1994) A transcribed polymorphism and sub-localisation of MDM2. Hum Genet 93:611-612.
14. Imai T, Olson MV (1990) Second-generation approach to the construction of yeast artificial-chromosome libraries. Genomics 8:297-303.
15. Jankowski SA, Mitchell DS, Smith SH, Trent JM, Meltzer PS (1994) SAS, a gene amplified in human sarcomas, encodes a new member of the transmembrane 4 superfamily of proteins. Oncogene 9:1205-1211.
16. Kallioniemi OP, Kallioniemi A, Sudar D, Rutovitz D, Gray JW, Waldman F, Pinkel D (1993) Comparative genomic hybridization: A rapid new method for detecting and mapping DNA amplification in tumors. Semin Cancer Biol 4:41-46.
17. Khatib ZA, Matsushime H, Valentine M, Shapiro DN, Sherr CJ, Look AT (1993) Coamplification of the CDK4 gene with MDM2 and GLI in human sarcomas. Cancer Research 53:5535-5541.
18. Kinzler KW, Bigner SH, Bigner DD, Trent JM, Law ML, O'Brien SJ, Wong AJ, Vogelstein B (1987) Identification of an amplified, highly expressed gene in a human glioma. Science 236:70-73.
19. Leach FS, Tokino T, Meltzer P, Burrell M, Oliner JD, Smith S, Hill DE, Sidransky D, Kinzler KW, Vogelstein B (1993) p53 Mutation and MDM2 amplification in human soft tissue sarcomas. Cancer Res 53:2231-2234.
20. Meltzer PS, Jankowski SA, Dal Cin P, Sandberg AA, Paz IB, Coccia MA (1991) Identification and cloning of a novel amplified DNA sequence in human malignant fibrous histiocytoma derived from a region of chromosome 12 frequently rearranged in soft tissue tumors. Cell Growth Diff 2:495-501.
21. Mendez MJ, Klapholz S, Brownstein BH, Gemmill RM (1991) Rapid screening of a YAC library by pulsed-field gel Southern blot analysis of pooled YAC clones. Genomics 10:661-665.
22. Mitchell D, Guan X-Y, Meltzer PS (1994) Detection of chromosome 12q amplification in sarcomas by chromosome microdissection and interphase FISH. Int J Oncol 5:787-792.
23. Oliner JD, Kinzler KW, Meltzer PS, George DL, Vogelstein B (1992) Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature 358:80-83.
24. Pedeutour F, Suijkerbuijk RF, Forus A, Van Gaal J, Van de Klundert W, Coindre JM, Nicolo G, Collin F, Van Haelst U, Huffermann K, et al. (1994) Complex composition and coamplification of SAS and MDM2 in ring and giant rod marker chromosomes in well differentiated liposarcoma. Genes Chromosom Cancer 10:85-94.
25. Pinkel D, Straume T, Gray JW (1986) Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization. Proc Natl Acad Sci USA 83:2934-2938.
26. Reifenberger G, Liu L, Ichimura K, Schmidt EE, Collins VP (1993) Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations. Cancer Res 53:2736-2739.
27. Reifenberger G, Reifenberger J, Ichimura K, Meltzer PS, Collins VP (1994) Amplification of multiple genes from chromosomal region 12q13-14 in human malignant gliomas: Preliminary mapping of the amplicons shows preferential involvement of CDK4, SAS, and MDM2. Cancer Res 54:4299-4303.
28. Riou G, Barrois M, Prost S, Terrier M, Theodore C, Levine AJ (1995) The p53 and mdm-2 genes in human testicular germ-cell tumors. Mol Carcinogen 12:124-131.
29. Roberts WM, Douglass EC, Peiper SC, Houghton PJ, Look AT (1989) Amplification of the gli gene in childhood sarcomas. Cancer Res 49:5407-5413.
30. Smith SH, Weiss SW, Jankowski SA, Coccia MA, Meltzer PS (1992) SAS amplification in soft tissue sarcomas. Cancer Res 52:3746-3749.
31. Su YA, Trent JM, Guan XY, Meltzer PS (1994) Direct isolation of genes encoded within a homogeneously staining region by chromosome microdissection. Proc Natl Acad Sci USA 91:9121-9125.