Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 26, 1996, Pages 15030-15035

  Wu, Hao ^a   Myszka, David G ^b,d   Tendian, Susan W ^c   Brouillette, Christie G ^c   Sweet, Ray W ^b   Chaiken, Irwin M ^b,e   Hendrickson, Wayne A ^a  

^a Columbia University ^*  (United States)

^b GLAXOSMITHKLINE   (United Kingdom)

^c SOUTHERN RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CELL SURFACE RECEPTOR; ENVELOPE PROTEIN; GLYCOPROTEIN GP 120; T LYMPHOCYTE ANTIGEN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING KINETICS; CRYSTALLOGRAPHY; HUMAN IMMUNODEFICIENCY VIRUS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; T LYMPHOCYTE; THERMOSTABILITY; VIRUS ADSORPTION; VIRUS ENVELOPE;

ANTIGENS, CD4; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HIV ENVELOPE PROTEIN GP120; HUMANS; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; THERMODYNAMICS; UREA;

EID: 0030446301     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.26.15030     Document Type: Article

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