Differential regulation of TGF-β2 by hormones in rat uterus and mammary gland

Journal of Reproductive Immunology

Volumn 32, Issue 2, 1996, Pages 125-144

  Schneider, Sara L ^a   Gollnick, Sandra O ^a   Grande, Catherine ^a   Pazik, James E ^a   Tomasi, Thomas B ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

Mammary gland; TGF 2; Uterus

Indexed keywords

ESTROGEN; MESSENGER RNA; PROLACTIN; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BREAST EPITHELIUM; BREAST MILK; CONTROLLED STUDY; FEMALE; HORMONAL REGULATION; LACTATION; MAMMARY GLAND; MATERNAL PLASMA; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; RAT; RNA TRANSCRIPTION; UTERUS; UTERUS FLUID;

ANIMALS; ENZYME-LINKED IMMUNOSORBENT ASSAY; ESTRADIOL; FEMALE; GONADAL STEROID HORMONES; MAMMARY GLANDS, ANIMAL; MILK; ORGAN SPECIFICITY; PREGNANCY; PROLACTIN; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA; UTERUS;

EID: 0030446262     PISSN: 01650378     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0378(96)00997-7     Document Type: Article

References (67)

1. Altman, D.J., Schneider, S.L., Thompson, D.A., Cheng, H-L. and Tomasi, T.B. (1990) A TGF-β2-like immunosuppressive factor in amniotic fluid and localization of TGF-β2 mRNA in the pregnant uterus. J. Exp. Med. 172, 1391-1401.
2. Aronica, S.M., Kraus, W.L. and Katzenellenbogen, B.S. (1994) Estrogen action via the cAMP signaling pathway: Stimulation of adenylate cyclase and cAMP-regulated gene transcription. Proc. Natl. Acad. Sci. USA 91, 8517-8521.
3. Arrick, B.A., Korc, M. and Derynck, R. (1990) Differential regulation of three transforming growth factor β species in human breast cancer cell lines by estradiol. Cancer Res. 50, 299-303.
4. Bascom, C.C., Wolfshohl, J.R., Coffey, R.J., Jr., Madisen, L., Webb, N.R., Purchio, A.R., Derynck, R. and Moses, H.L. (1989) Complex regulation of transforming growth factor β1, β2, β3 mRNA expression in mouse fibroblasts and keratinocytes transforming growth factors β1 and β2. Mol. Cell. Biol. 9, 5508-5515.
5. Burt, D.W., Paton, I.R. and Dey, B.R. (1991) Comparative analysis of human and chicken transforming growth factor-β2 and β3 promoters. J. Mol. Endocrinol. 7, 175-183.
6. Cheng, H-L., Schneider, S.L., Kane, C.M., Gollnick, S.O., Grande, C., Thompson, D., Pietrzak, E. and Tomasi, T.B. (1993) TGF-β2 gene and protein expression in maternal and fetal tissues at various stages of murine development. J. Reprod. Immunol. 25, 133-148.
7. Chomczynski, P. and Sacchi, N. (1987) Single step method of RNA isolation by acid guanidinium thiocynate-phenol-chloroform extract. Anal. Biochem. 162, 152-159.
8. Clark, D.A., Flanders, K.C., Banwatt, D., Millar-Book, W., Manuel, J., Stedronska-Clark, J. and Rowley, B. (1990) Murine pregnancy decidua produces a unique immunosuppressive molecule related to transforming growth factor β-2. J. Immunol. 144, 3008-3014.
9. Clark, D.A., Flanders, K.C., Hirte, H., Dasch, J.R., Coker, R., McAnulty, R.J. and Laurent, G.J. (1995) Characterization of murine pregnancy decidua transforming growth factor beta. I. Transforming growth factor beta 2-like molecules of unusual molecular size released in bioactive form. Biol. Reprod. 52, 1380-1388.
10. Cooke, N.W. (1995) Prolactin: Basic physiology. In: Endocrinology, Vol. 1 (DeGroot, L.J. et al., eds.), 3rd edn. pp. 368-393. W.B. Saunders, Philadelphia, PA, USA.
11. Cox, D. and Burk, R.R. (1991) Isolation and characterisation of milk growth factor, a transforming-growth-factor-β2-related polypeptide, from bovine milk. Eur. J. Biochem. 197, 353-358.
12. Daniel, C.W. and Robinson, S.D. (1992) Regulation of mammary growth and function by TGF-β. Mol. Reprod. Development 32, 145-151.
13. Danielpour, D. (1993) Improved sandwich enzyme-linked immunosorbent assays for transforming growth factor β1. J. Immunol. Methods 158, 17-25.
14. Danielpour, D., Kim, K.Y., Dart, L.L., Watanabe, S., Roberts, A.B. and Sporn, M.B. (1990) Evidence for differential regulation of TGFβ and TGFβ2 expression in vivo by sandwich enzyme-linked immunosorbent assays. Annals NY Acad. Sci. 593, 300-302.
15. Das, S.K., Flanders, K.C., Andrews, G.K. and Dey, S.K. (1992) Expression of transforming growth factor-β isoforms (β2 and β3) in the mouse uterus: Analysis of the periimplantation period and effects of ovarian steroids. Endocrinol, 130, 3459-3466.
16. Dasch, J.R., Pace, D.R., Waegell, W., Inenaga, D. and Ellingsworth, L. (1989) Monoclonal antibodies recognizing transforming growth factor-β, bioactivity neutralization and transforming growth factor β2 affinity purification. J. Immunol, 142, 1536-1541.
17. +) RNA on oligo (dT) cellulose. In: Basic Methods in Molecular Biology, pp. 139-142. Academic Press, New York.
18. Decks, S., Richards, J. and Nandi, S. (1988) Maintenance of normal rat mammary epithelial cells by insulin and insulin-like growth factor 1. Exp. Cell Res. 174, 448-460.
19. Geiser, A.G., Busam, K.J., Kim, S.J., Lafyatis, R., O'Reilly, M.A., Webbink, R., Roberts, A.B. and Sporn, M.B. (1993) Regulation of the transforming growth factor-β1 and β3 promoters by transcription factor Spl. Gene 129, 223-228.
20. Geiser, A.G., Kim, S.J., Roberts, A.B. and Sporn, M.B. (1991) Characterization of the mouse transforming growth factor -β1 promoter and activation by the Ha-ras oncogene. Mol. Cell Biol. 11, 84-92.
21. Kalra, P.S., Fawcett, C.P., Krulich, L. and McCann, S.M. (1973) The effects of gonadal steroids on plasma gonadotropins and prolactin in the rat. Endocrinol. 92, 1256-1268.
22. Kameda, T., Matsuzaki, N., Sawai, K., Okada, T., Saji, F., Matsuda, T., Hirano, T., Kishimoto, T. and Tanizawa, O. (1990) Production of interleukin-6 by normal human trophoblast. Placenta II, 205-213.
23. Katz, J., Wals, P.A. and Van de Velde, R.L. (1974) Lipogenesis by Acini from mammary gland of lactating rats. J. Biol. Chem. 249, 7348-7357
24. Kelly, D., O'Reilly, M.A. and Rizzino, A. (1992) Differential regulation of the transforming growth factor type-β2 gene promoter in embryonal carcinoma cells and their differentiated cells. Develop. Biol. 153, 172-175.
25. Kim, S-J., Glick, A., Sporn, M.B. and Roberts, A.B. (1989) Characterization of the promoter region of the human transforming growth factor-β1 gene. J. Biol. Chem. 264, 402-408.
26. Kim, S-J., Park, K., Koeller, D., Kim, K.Y., Wakefield, L.M., Sporn, M.B. and Roberts, A.B. (1992) Post-transcriptional regulation of the human transforming growth factor-β gene. J. Biol. Chem. 267, 13702-13707.
27. Kopp, A., Jonat, W., Schmahl, M. and Knabbe, C. (1995) Transforming growth factor β2 (TGF-β2) levels in plasma of patients with metastatic breast cancer treated with tamoxifen. Cancer Res. 55, 4512-4515.
28. 4. Nature 227, 680-685.
29. Lafyatis, R., Denhez, F., Williams, T., Sporn, M.B. and Roberts, A.B. (1991) Sequence specific protein binding to and activation of the TGF-β3 promoter through a repeated TCCC motif. Nucleic Acids Res. 19, 6419-6425.
30. Lafyatis, R., Lechleider, R., Kim, S.J., Jakowlew, S., Roberts, A.B. and Sporn, M.B. (1990) Structural and functional characterization of the transforming growth factor β3 promoter. J. Biol. Chem. 265, 19128-19136.
31. Larson, B.L. and Jorgensen, G.N. (1974) Biosynthesis of the milk proteins. In: Lactation, a Comprehensive Treatise, Vol. II, Biosynthesis and Secretion of Milk/Diseases, (Larson, B.L. and Smith, V.R., eds.), pp. 115-146. Academic Press, New York.
32. Letterio, J.J., Geiser, A.G., Kulkarni, A.B., Roche, N.S., Sporn, M.B. and Roberts, A.B. (1994) Maternal rescue of transforming growth factor-β1 null mice. Sci. 264, 1936-1938.
33. Lin, H., Mosmann, T.R., Guilbert, L., Tuntipopipat, S. and Wegmann, T.G. (1993) Synthesis of T helper 2-type cytokines at the maternal-fetal interface. J. Immunol. 151, 4562-4573.
34. Madisen, L., Webb, N.R., Rose, T.M., Marquardt, H., Ikeda, T., Twardzik, D., Seyedin, S. and Purchio, A.F. (1988) Transforming growth factor-β2: cDNA cloning and sequence analysis. DNA 7, 1-8.
35. Malipiero, U., Holler, M., Werner, U. and Fontana, A. (1990) Sequence analysis of the promoter region of the glioblastoma derived T cell suppressor factor/transforming growth factor (TGF)-β2 gene reveals striking differences to the TGF-β1 and β3 genes. Biochem. Biophys. Res. Comm. 171, 1145-1147.
36. Maurer, R.A. and Gorski, J. (1977) Effects of estradiol-17β and pimozide on prolactin synthesis in male and female rats. Endocrinology 101, 76-84.
37. McGuire, M.K., Butler, W.R. and Rasmussen, K.M. (1992) Chronic food restriction amplifies the effect of lactation on the duration of postpartum anestrus in rats. J. Nutrition 122, 1726-1730.
38. Meyuhas, O. and Perry, R.P. (1980) Contraction and identification of cDNA clones for mouse ribosomal proteins: Application for the study of r-protein gene expression. Gene 10, 113-129.
39. Mitchell, M.D., Trautman, M.S. and Dudley, D.J. (1993) Cytokine networking in the placenta. Placenta 14, 249-275.
40. Nishino, E., Matsuzaki, N., Masuhiro, K., Kameda, T., Taniguchi, T., Takagi, T., Saji, F. and Tanizawa, O. (1990) Trophoblast-derived interleukin-6 (IL-6) regulates human chorionic gonadotropin release through IL-6 receptor on human trophoblasts. J. Clin. Endocrinol. Metabol. 71, 436-441.
41. Noma, T., Glick, A.B., Geiser, A.G., O'Reilly, M.A., Miller, J., Roberts, A.B. and Sporn, M.B. (1991) Molecular cloning and structure of the human transforming growth factor-β2 gene promoter. Growth Factors 4, 247-255.
42. Ohta, M., Greenberger, J.S., Anklesaria, P., Bassols, A. and Massague, J. (1987) Two forms of transforming growth factor-β distinguished by multipotential haematopoietic progenitor cells. Nature 329, 539-541.
43. O'Reilly, M.A., Geiser, A.G., Kim, S.J., Bruggeman, L.A., Luu, A.X., Roberts, A.B. and Sporn, M.B. (1992) Identification of an activating transcription factor (ATF) binding site in the human transforming growth factor-β2 promoter. J. Biol. Chem. 267, 19938-19943.
44. Pollard, J.W., Bartocci, A., Arceci, R., Orlofsky, A., Ladner, M.B. and Stanley, E.R. (1987) Apparent role of the macrophage growth factor, CSF-1, in placental development. Nature 330, 484-486.
45. Rennison, M.E., Kerr, M., Addey, C.V.P., Handel, S.E., Turner, M.D., Wilde, C.J. and Burgoyne, R.D. (1993) Inhibition of constitutive protein secretion from lactating mouse mammary epithelial cells by FIL (feedback inhibitor of lactation), a secreted milk protein. J. Cell Sci. 106, 641-648.
46. Roberts, A.B. and Sporn, M.B. (1992) Differential expression of the TGF-β isoforms in embryogenesis suggests specific roles in developing and adult tissues. Mol. Reprod. Develop. 32, 91-98.
47. Robertson, S.A., Mayrhofer, G. and Seamark, R.F. (1992) Uterine epithelial cells synthesize GM-CSF and IL-6 in pregnant and nonpregnant mice. Biol. Reprod. 46, 1069-1079.
48. Robinson, S.D., Roberts, A.B. and Daniel, C.W. (1993) TGFβ suppresses casein synthesis in mouse mammary explants and may play a role in controlling milk levels during pregnancy. J. Cell Biol. 120, 245-251.
49. Robinson, S.D., Silberstein, G.B., Roberts, A.B., Flanders, K.C. and Daniel, C.W. (1991) Regulated expression and growth inhibitory effects of transforming growth factor-β isoforms in mouse mammary gland development. Development 113, 867-878.
50. Rosa, F., Roberts, A.B., Danielpour, D., Dart, L.L., Sporn, M.B. and Dawid, I.G. (1988) Mesoderm induction in amphibians: The role of TGF-β2-like factors. Science 239, 783-785.
51. Saacke, R.G. and Heald, C.W. (1974) Cytological aspects of milk formation and secretion. In: Lactation, a Comprehensive Treatise, Vol. II, Biosynthesis and Secretion of Milk/Diseases, (Larson, B.L. and Smith, V.R. eds.), pp. 147-189. Academic Press, New York.
52. Sanderson, N., Factor, V., Nagy, P., Kopp, J., Kondaiah, P., Wakefield, L., Roberts, A.B., Sporn, M.B. and Thorgeirsson, S.S. (1995) Hepatic expression of mature transforming growth factor β1 in transgenic mice results in multiple tissue lesions. Proc. Natl. Acad. Sci. USA 92, 2572-2576.
53. Schmid, P., Cox, D., Bilbe, G., Maier, R. and McMaster, G.K. (1991) Differential expression of TGF-β1, β2, and β3 genes during mouse embryogenesis. Development 111, 117-130.
54. Scotto, L. and Assoian, R.K. (1993) A GC-rich domain with bifunctional effects on mRNA and protein levels: Implications for control of transforming growth factor β1 expression. Mol. Cell. Biol. 13, 3588-3597.
55. Shen, M.M. and Leder, P. (1992) Leukemia inhibitory factor is expressed by the preimplantation uterus and selectively blocks primitive ectoderm formation in vitro. Proc. Natl. Acad. Sci. USA 89, 8240-8244.
56. Springer, T., Galfre, G., Secher, D.S. and Milstein, C. (1979) Mac 1: a macrophage differentiation antigen identified by monoclonal antibody. Eur. J. Immunol. 9, 301-306.
57. Terranova, P.F., Hunter, V.J., Roby, K.F. and Hunt, J.S. (1995) Tumor necrosis factor-alpha in the female reproductive tract. Proc. Soc. Exp. Biol. Med. 209, 325-342.
58. Tokuyama, H. and Tolluyama, Y. (1989) Bovine colostric transforming growth factor-β-like peptide that induces growth inhibition and changes in morphology of human osteogenic sarcoma cells (MG-63). Cell Biol. Int. Rep. 13, 251-258.
59. Tora, L., Gaub, M.P., Mader, S., Dierich, A., Bellard, M. and Chambon, P. (1988) Cell-specific activity of a GGTCA half-palindromic oestrogen-responsive element in the chicken ovalbumin gene promoter. EMBO J. 7, 3771-3778.
60. Van der Schoot, P., Lankhorst, R., De Roo, J.A. and De Greef, W.J. (1978) Suckling stimulus, lactation, and suppression of ovulation in the rat. Endocrinol. 103, 949-956.
61. Wager, R.E. and Assoian, R.K. (1990) A phorbol ester-regulated ribonuclease system controlling transforming growth factor β1 gene expression in hematopoietic cells. Mol. Cell. Biol. 10, 5983-5990.
62. Wakefield, L., Kim, S-J., Glick, A., Winokur, T., Colletta, A. and Sporn, M. (1990) Regulation of transforming growth factor-β subtypes by members of the steroid hormone superfamily. J. Cell Sci. Suppl. 13, 139-148.
63. Wakefield, L.M., Letterio, J.J., Chen, T., Danielpour, D., Allison, R.S.H., Pai, L.H., Denicoff, A.M., Noone, M.H., Cowan, K.H., O'Shaughnessy, A. and Sporn, M.B. (1995) Transforming growth factor-β1 circulates in normal human plasma and is unchanged in advanced metastatic breast cancer. Clin. Cancer Res. 1, 129-136.
64. 2-macroglobulin. J. Biol. Chem. 269, 30402-30406.
65. Wilde, C.J., Addey, C.V.P., Boddy, L.M. and Peaker, M. (1995) Autocrine regulation of milk secretion by a protein in milk. Biochem. J. 305, 51-58.
66. Wira, C.R., BodwelL J.E. and Prabhala, R.H. (1991) In vivo response of secretory component in the rat uterus to antigen, IFN-γ, and estradiol. J. Immunol. 146, 1893-1899.
67. Wira, C.R., Sullivan, D.A. and Sandoe, C.P. (1983) Estrogen-mediated control of the secretory immune system in the uterus of the rat. Ann. NY Acad. Sci. 409, 534-551.