Neurochemical and behavioral recovery after colchicine lesions of the nucleus basalis magnocellularis in rats

Restorative Neurology and Neuroscience

Volumn 10, Issue 3, 1996, Pages 135-146

  Shaughnessy, Laura W ^a   Barone Jr , Stanley ^b   Mundy, William R ^b   Tilson, Hugh A ^b  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

ChAT activity; lesion induced compensation; nucleus basalis; passive avoidance; water maze

Indexed keywords

CHOLINE ACETYLTRANSFERASE; COLCHICINE;

ANIMAL EXPERIMENT; ARTICLE; AVOIDANCE BEHAVIOR; BEHAVIOR; BRAIN INJURY; LEARNING; MAGNOCELLULAR NUCLEUS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TASK PERFORMANCE;

EID: 0030446150     PISSN: 09226028     EISSN: None     Source Type: Journal    
DOI: 10.3233/rnn-1996-10302     Document Type: Article

References (56)

1. Alheid, G.F. and Heimer, L., New perspectives in basal forebrain organization of special relevance for neuropsychiatric disorders: The striatopallidal, amygdaloid, and corticopetal components of substantia innominata, Neurosci., 27 (1988) 1-39.
2. Barone, S. Jr., Bonner, M., Tandon, P., McGinty, J.F. and Tilson, H.A., The neurobiological effects of colchicine: modulation by nerve growth factor, Brain Res. Bull., 28 (1992) 265-274.
3. Bartus, R.T., Dean, R.L., Pontecorvo, M.J. and Flicker, C., The cholinergic hypothesis: a historical overview, current perspective, and future directions, Ann. N.Y. Acad. Sci., 444 (1985a) 332-358.
4. Bartus, R.T., Flicker, C., Dean, R.L., Pontecorvo, M.J., Figueiredo, M.J. and Fisher, S.K., Selective memory loss following nucleus basalis lesions: Long term behavioral recovery despite persistent cholinergic deficiencies, Pharm. Biochem. Behav., 23 (1985b) 125-135.
5. Baskerville, K.A., Chang, H.T. and Herron, P., Topography of cholinergic afferents from the nucleus basalis of meynert to representational areas of sensorimotor cortices in the rat, J. Comp. Neurol., 335 (1993) 552-562.
6. Berger-Sweeney, J., Heckers, S., Mesulam, M.-M., Wiley, R.G., Lappi, D.A. and Sharma, M., Differential effects on spatial navigation of immunotoxin-induced cholinergic lesions of the medial septal area and nucleus basalis magnocellularis, J. Neurosci., 14 (1994) 4507-4519.
7. Boegman, R.J., Cockhill, J., Jhamandas, K. and Beninger, R.J., Excitotoxic lesions of rat basal forebrain: Differential effects of choline acetyltransferase in the cortex and amygdala, Neurosci., 51 (1992) 129-135.
8. Book, A.A, Wiley, R.G. and Schweitzer, J.B., Specificity of 192 IgG-saporin for NGF receptor-positive cholinergic basal forebrain neurons in the rat, Brain Res., 590 (1992) 350-355.
9. Connor, D.J., Thal, L.J., Mandel, R.J., Langlais, P.J. and Masliah, E., Independent and nucleus basalis magnocellularis lesion: Maze learning, cortical neurochemistry, and morphometry, Behav. Neurosci., 106 (1992) 776-788.
10. Cossette, P., Umbriaco, D., Zamar, N., Hamel, E. and Descarries, L., Recovery of choline acetyltransferase activity without sprouting of the residual acetylcholine innervation in adult rat cerebral cortex after lesion of the nucleus basalis, Brain Res., 630 (1993) 195-206.
11. Dekker, A.J.A.M., Connor, D.J. and Thal, L.J., The role of cholinergic projections from the nucleus basalis in memory, Neurosci. Biobehav. Rev., 15 (1991) 299-317.
12. Deutsch, J.A., The cholinergic synapse and the site of memory, Science, 174 (1971) 788-794.
13. Dunnett, S.B., Whishaw, I.Q., Jones, G.H. and Bunch, S.T., Behavioral, biochemical and histochemical effects of different neurotoxic amino acids injected into nucleus basalis magnocellularis of rats, Neurosci., 20 (1987) 653-669.
14. Fibiger, H.C., The organization and some projections of cholinergic neurons of the mammalian forebrain, Brain Res. Rev., 4 (1982) 327-388.
15. Fonnum, F., A rapid radiochemical method of the determination of choline acetyltransferase, J. Neurochem., 24 (1975) 407-409.
16. Gardiner, I.M., De Belleroche, J., Premi, B.K. and Hamilton, M.H., Effect of lesion of the nucleus basalis of rat on acetylcholine release in cerebral cortex: time course of compensatory events, Brain Res., 407 (1987) 263-271.
17. Hedreen, J.C., Bacon, S.J. and Price, D.L., A modified histochemical technique to visualize acetylcholinesterase-containing axons, J. Histochem., 33 (1985) 134-140.
18. Hong, J.S., Yang, H.-Y.T., Fratta, W. and Costa, E., Determination of methionine enkephalin in discrete regions of rat brain, Brain Res., 134 (1977) 383-386.
19. Kesner, R.P., Berman, R.F. and Tardif, R., Place and taste aversion learning: role of basal forebrain, parietal cortex, and amygdala, Brain Res. Bull., 29 (1992) 345-355.
20. Kharlamov, A., Zivkovic, I., Polo, A., Armstrong, D.M., Costa, E. and Guidotti, A., LIGA20, a lyso derivative of ganglioside GM1, given orally after cortical thrombosis reduces infarct size and associated cognition deficit, Proc. Nat. Acad. Sci. USA, 91 (1994) 6303-6307.
21. Kramer, C.V., Extension of multiple range tests to group means with unequal numbers of replications, Biometrics, 12 (1956) 307-310.
22. Lowry, O.H., Rosebrough, N.J., Farr, A.I. and Randall, R.J., Protein measurement with folin-phenol reagent, J. Biol. Chem., 193 (1951) 265-275.
23. Mandel, R.J., Gage, F.H. and Thal, L.J., Enhanced detection of nucleus basalis magnocellularis lesion-induced spatial learning deficits by modification of training regimen, Behav. Brain Res., 31 (1989) 221-229.
24. Mesulam, M.-M., Mufson, E.J., Wainer, B.H. and Levy, A.I., Central cholinergic pathways in the rat: An overview based on an alternative nomenclature (Ch1-Ch6), Neurosci., 10 (1983) 1185-1201.
25. Morris, R.G.M., Spatial localization does not require the presence of local cues, Learning and Motivation, 12 (1981) 236-260.
26. Mugnaini, E. and Oertel, W.H., In A. Björklund and T. Hökfelt (eds.), Handbook of Chemical Neuroanatomy, Vol 4, GABA and neuropeptides in CNS Pt I, Elsevier, New York, 1985, pp 436-608.
27. Mundy, W.R. and Tilson, H.A., Neurochemical recovery in the neocortex after colchicine lesions of the nucleus basalis magnocellularis in rats, Brain Res. Bull., 25 (1990) 207-209.
28. Mundy, W.R., Barone, S. and Tilson, H.A., Neurotoxic lesions of the nucleus basalis induced by colchicine: effects on spatial navigation in the water maze, Brain Res., 512 (1990) 221-228.
29. Nagai, T., Kimura, H., Maeda, T., McGeer, P.L. Peng, F. and McGeer, E.G., Cholinergic projections from the basal forebrain of the rat to the amygdala, J. Neurosci., 2 (1982) 513-520.
30. Nakamura, S. and Ishihara, T., Task-dependent memory loss and recovery following unilateral nucleus basalis lesion: behavioral and neurochemical correlation, Behav. Brain Res., 39 (1990) 113-122.
31. Nitta, A., Hayashi, K., Hasegawa, T. and Nabeshima, T., Development of plasticity of brain function with repeated trainings and passage of time after basal forebrain lesions in rats, J. Neural Transm., 93 (1993) 37-46.
32. Opello, K.D., Stackman, R.W., Ackerman, S. and Walsh., T.J., AF64A (Ethylcholine mustard aziridinium) impairs acquisition and performance of a spatial, but not a cued water maze task: relation to cholinergic hypofunction, Physiol. Behav., 54 (1993) 1227-1233.
33. Page, K.J., Everitt, B.J., Robbins, B.W., Marston, H.M. and Wilkinson L.S., Dissociable effects on spatial maze and passive avoidance acquisition and retention following AMPA- and ibotenic acid-induced excitotoxic lesions of the basal forebrain in rats: differential dependence on cholinergic neuronal loss, Neurosci., 43 (1991) 457-472.
34. Pang, K., Williams, M.J., Egeth, H. and Olton, D.S., Nucleus basalis magnocellularis and attention: effects of muscimol infusions, Behav. Neurosci., 107 (1993) 1031-1038.
35. Parent M.B. and McGaugh, J.L., Posttraining infusion of lidocaine into the amygdala basolateral complex impairs retention of inhibitory avoidance training, Brain Res., 661 (1994) 97-103.
36. Paxinos, G. and Watson, C., The Rat Brain in Stereotaxic Coordinates, Academic, New York, 1986.
37. Perry, E.K., Tomlinson, B.E., Blessed, G., Bergmann, K., Gibson, P.H. and Perry, R.H., Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia, Br. Med. J., 2 (1978) 1457-1459.
38. Reiter, L.W., Anderson, G.E., Laskey, J.W. and Cahill, D.F., Developmental and behavioral changes in the rat during chronic exposure to lead, Environ. Health Perspectives, 12 (1975) 119-123.
39. Riekkinen, P. Jr., Riekkinen, M. and Sirviö, J., Cholinergic drugs regulate passive avoidance performance via the amygdala, J. Pharm. Exp. Therapeutics, 267 (1993) 1484-1492.
40. Robbins, T.W., Everitt, B.J., Marston, H.M., Wilkinson, J., Jones, G.H. and Page K.J., Comparative effects of ibotenic acid-and quisqualic acid-induced lesions of the substantia innominata on attentional function in the rat: implications for the role of the cholinergic neurons of the nucleus basalis in cognitive processes, Behav. Brain Res., 35 (1989) 221-240.
41. Roßner, S., Schliebs, R. and Bigl, V., Ibotenic acid lesion of nucleus basalis magnocellularis differentially affects cholinergic, glutamatergic and GABAergic markers in cortical rat brain regions, Brain Res., 668 (1994) 85-99.
42. Rye, D.B., Wainer, B.H., Mesulam, M.-M., Mufson, E.J. and Saper, C.B., Cortical projections arising from the basal forebrain: A study of cholinergic and non-cholinergic components employing combined retrograde tracing and immunohistochemical localization of choline acetyltransferase, Neurosci., 13 (1984) 627-643.
43. Saper, C.B., Organization of cerebral cortical afferent systems in the rat. II. Magnocellular basal nucleus, J. Comp. Neurol., 222 (1984) 313-342.
44. Sarter, M. and Dudchenko, P., Dissociative effects of ibotenic and quisqualic acid- induced basal forebrain lesions on cortical acetylcholinesterase-positive fiber density and cytochrome oxidase activity, Neurosci., 41 (1991) 729-738.
45. SAS Institute Inc., SAS/STAT User's Guide, Version 6, Fourth Edition, Volume 2. Cary, NC: SAS Institute Inc., 1989, pp. 846.
46. Shaughnessy, L.W., Barone, S. Jr., Mundy, W.R., Herr, D.W. and Tilson, H.A., Comparison of intracranial infusions of colchicine and ibotenic acid as models of neurodegeneration in the basal forebrain, Brain Res., 637 (1994) 15-26.
47. Simantov, R., Kuhar, M.J. and Snyder, S.H., Opioid peptide enkephalins: immunohistochemical mapping in the rat central nervous system, Proc. Nat. Acad. Sci., 14 (1977) 2167-2171.
48. Smith, G., Animal models of Alzheimer's disease: experimental cholinergic denervation, Brain Res. Rev., 13 (1988) 103-118.
49. Stephens, P.H., Tagari, P.C. and Cuello, A.C., Age-related variations in plasticity of rat basal forebrain cholinergic neurons after cortical lesions, Brain Res., 448 (1988) 320-324.
50. Steward, O., Goldschmidt, R.B. and Sutula, T., Neurotoxicity of colchicine and other tubulin-binding agents: a selective vulnerability of certain neurons to the disruption of microtubules, Life Sci., 35 (1984) 43-51.
51. Tilson, H.A., McLamb, R.L. Shaw, S., Rogers, B.C., Pediaditaskis, P. and Cook L., Radial-arm maze deficits produced by colchicine administered into the area of the nucleus basalis are ameliorated by cholinergic agents, Brain Res., 438 (1988) 83-94.
52. Torres, E.M., Perry, T.A., Blokland, A., Wilkinson, L.S., Wiley, R.G., Lappi, D.A. and Dunnett, S.B., Behavioral, histochemical and biochemical consequences of selective immunolesions in discrete regions of the basal forebrain cholinergic system, Neurosci., 63 (1994) 95-122.
53. Wenk, G.L. and Olton, D.S., Recovery of neocortical choline acetyltransferase activity following ibotenic acid injection into the nucleus basalis of Meynert in rats, Brain Res., 293 (1984) 184-186.
54. Whitehouse, P.J., Price, D.L., Struble, R.G., Clark, A.W., Coyle, J.T., and Delong, M.R., Alzheimer's disease and senile dementia: Loss of neurons in the basal forebrain, Science, 215 (1982) 1237-1239.
55. Wilcock, G.L., Esiri, M.M., Bowen, D.M. and Smith, C.C.T., Alzheimer's disease: Correlation of cortical choline acetyltransferase activity with severity of dementia and histological abnormalities, J. Neurol. Sci., 57 (1982) 407-417.
56. Winkler, J., Suhr, S.T., Gage, F.H., Thal, L.J. and Fisher, L.J., Essential role of neocortical acetylcholine in spatial memory, Nature, 375 (1995) 484-487.