메뉴 건너뛰기




Volumn 137, Issue 12, 1996, Pages 5624-5633

Steady-state regulation of whole-body thyroid hormone pool sizes and interconversion rates in hypothyroid and moderately T3-stimulated rats

Author keywords

[No Author keywords available]

Indexed keywords

LIOTHYRONINE; THYROID HORMONE; THYROXINE; TRACER;

EID: 0030445805     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.12.8940393     Document Type: Article
Times cited : (10)

References (44)
  • 1
    • 0017962719 scopus 로고
    • 3 receptors and acute inhibition of TSH release
    • 3 receptors and acute inhibition of TSH release. J Clin Invest 61:1247-1259
    • (1978) J Clin Invest , vol.61 , pp. 1247-1259
    • Silva, J.E.1    Larsen, P.R.2
  • 2
    • 0018890825 scopus 로고
    • The effect of graded doses of thyroxine on plasma thyrotropin concentration in rats made hypothyroid by thyroidectomy or propylthiouracil
    • Tonooka N, Greer MA 1980 The effect of graded doses of thyroxine on plasma thyrotropin concentration in rats made hypothyroid by thyroidectomy or propylthiouracil. Endocrinology 106:818-822
    • (1980) Endocrinology , vol.106 , pp. 818-822
    • Tonooka, N.1    Greer, M.A.2
  • 3
    • 0018866216 scopus 로고
    • Feedback effectiveness of periodic vs. constant triiodothyronine replacement
    • Connors JM, Hedge GA 1980 Feedback effectiveness of periodic vs. constant triiodothyronine replacement. Endocrinology 106:911-917
    • (1980) Endocrinology , vol.106 , pp. 911-917
    • Connors, J.M.1    Hedge, G.A.2
  • 4
    • 0019463989 scopus 로고
    • Effect of continuous thyroxine administration on thyrotropin secretion in thyroidectomized rats
    • Connors JM and Hedge GA 1981 Effect of continuous thyroxine administration on thyrotropin secretion in thyroidectomized rats. Endocrinology 108:2198-2102
    • (1981) Endocrinology , vol.108 , pp. 2198-12102
    • Connors, J.M.1    Hedge, G.A.2
  • 5
    • 0024603950 scopus 로고
    • Serum thyrotropin concentrations are more highly correlated with serum triiodothyronine concentrations than with serum thyroxine concentrations in thyroid hormone-infused thyroidectomized rats
    • Emerson CH, Lew R, Braverman LE, DeVito WJ 1989 Serum thyrotropin concentrations are more highly correlated with serum triiodothyronine concentrations than with serum thyroxine concentrations in thyroid hormone-infused thyroidectomized rats. Endocrinology 124:2415-2418
    • (1989) Endocrinology , vol.124 , pp. 2415-2418
    • Emerson, C.H.1    Lew, R.2    Braverman, L.E.3    DeVito, W.J.4
  • 6
    • 0019490398 scopus 로고
    • Hypothyroidism in severely iodinedeficient rats
    • Okamura K, Taurog A, Krulich L 1981 Hypothyroidism in severely iodinedeficient rats. Endocrinology 109:464-468
    • (1981) Endocrinology , vol.109 , pp. 464-468
    • Okamura, K.1    Taurog, A.2    Krulich, L.3
  • 7
    • 0014871130 scopus 로고
    • Feedback regulation of TSH secretion in rats with hypothalamic lesions
    • Martin JB, Boshans R, Reichlin S 1970 Feedback regulation of TSH secretion in rats with hypothalamic lesions. Endocrinology 87:1032-1039
    • (1970) Endocrinology , vol.87 , pp. 1032-1039
    • Martin, J.B.1    Boshans, R.2    Reichlin, S.3
  • 8
    • 0023103073 scopus 로고
    • Replacement dose, metabolism and bioavailability of levothyroxine in the treatment of hypothyroidism: Role of triiodothyronine in pituitary feedback in humans
    • Fish LH, Schwartz HL, Cavanaugh J, Steffes MW, Bantle JP, Oppenheimer JH 1987 Replacement dose, metabolism and bioavailability of levothyroxine in the treatment of hypothyroidism: role of triiodothyronine in pituitary feedback in humans. N Engl J Med 3161:764-770
    • (1987) N Engl J Med , vol.3161 , pp. 764-770
    • Fish, L.H.1    Schwartz, H.L.2    Cavanaugh, J.3    Steffes, M.W.4    Bantle, J.P.5    Oppenheimer, J.H.6
  • 9
    • 0019754949 scopus 로고
    • Relationships between circulating and intracellular thyroid hormones: Physiological and clinical implications
    • Larsen PR, Silva JE, Kaplan MM 1981 Relationships between circulating and intracellular thyroid hormones: physiological and clinical implications. Endocr Rev 2:87-102
    • (1981) Endocr Rev , vol.2 , pp. 87-102
    • Larsen, P.R.1    Silva, J.E.2    Kaplan, M.M.3
  • 11
    • 0003126433 scopus 로고
    • Regulatory influences on iodothyronine deiodination in animal tissues
    • Hennemann G (ed) Marcel Dekker, New York
    • Kaplan MM 1985 Regulatory influences on iodothyronine deiodination in animal tissues. In: Hennemann G (ed) Thyroid Hormone Metabolism. Marcel Dekker, New York, pp 231-253
    • (1985) Thyroid Hormone Metabolism , pp. 231-253
    • Kaplan, M.M.1
  • 12
    • 0018177742 scopus 로고
    • The contribution of local tissue thyroxine monodeiodination to the nuclear 3,5,3′-triiodothyronine in pituitary, liver, and kidney of euthyroid rats
    • Silva JE, Dick TE, Larsen PR 1978 The contribution of local tissue thyroxine monodeiodination to the nuclear 3,5,3′-triiodothyronine in pituitary, liver, and kidney of euthyroid rats. Endocrinology 103:1196-1207
    • (1978) Endocrinology , vol.103 , pp. 1196-1207
    • Silva, J.E.1    Dick, T.E.2    Larsen, P.R.3
  • 13
    • 0018838537 scopus 로고
    • 3 binding in rat cerebral cortex and cerebellum
    • 3 binding in rat cerebral cortex and cerebellum. J Clin Invest 65:935-938
    • (1980) J Clin Invest , vol.65 , pp. 935-938
    • Crantz, F.R.1    Larsen, P.R.2
  • 14
    • 0020051327 scopus 로고
    • 3 specifically bound to nuclear receptors in rat cerebral cortex and cerebellum
    • 3 specifically bound to nuclear receptors in rat cerebral cortex and cerebellum. Endocrinology 110:367-375
    • (1982) Endocrinology , vol.110 , pp. 367-375
    • Crantz, F.R.1    Silva, J.E.2    Larsen, P.R.3
  • 15
    • 0021131139 scopus 로고
    • Production rates and turnover of T3 in rat-developing cerebral cortex and cerebellum: Responses to hypothyroidism
    • Silva JE, Mathews PS 1984 Production rates and turnover of T3 in rat-developing cerebral cortex and cerebellum: responses to hypothyroidism. J Clin Invest 74:1035-1049
    • (1984) J Clin Invest , vol.74 , pp. 1035-1049
    • Silva, J.E.1    Mathews, P.S.2
  • 17
    • 0020032672 scopus 로고
    • Effects of congenital hypothyroidism and partial and complete food deprivation on phenolic and tyrosyl ring iodothyronine doiodination in rat brain
    • Kaplan MM, Yaskoski KA 1982 Effects of congenital hypothyroidism and partial and complete food deprivation on phenolic and tyrosyl ring iodothyronine doiodination in rat brain. Endocrinology 110:761-767
    • (1982) Endocrinology , vol.110 , pp. 761-767
    • Kaplan, M.M.1    Yaskoski, K.A.2
  • 18
    • 0021090933 scopus 로고
    • Sources and quantity of 3,5,3′-triiodothyronine in several tissues of the rat
    • van Doom J, van del Heide D, Roelfsema F 1983 Sources and quantity of 3,5,3′-triiodothyronine in several tissues of the rat. J Clin Invest 72:1778-1792
    • (1983) J Clin Invest , vol.72 , pp. 1778-1792
    • Van Doom, J.1    Van Del Heide, D.2    Roelfsema, F.3
  • 19
    • 0022472190 scopus 로고
    • Conversion of thyroxine to 3,5,3′ -triiodothyronine in several rat tissues in vivo: The effect of hypothyroidism
    • Copenh
    • van Doom J, Roelfsema F, van der Heide D 1986 Conversion of thyroxine to 3,5,3′ -triiodothyronine in several rat tissues in vivo: the effect of hypothyroidism. Acta Endocrinol (Copenh) 113:59-64
    • (1986) Acta Endocrinol , vol.113 , pp. 59-64
    • Van Doom, J.1    Roelfsema, F.2    Van Der Heide, D.3
  • 20
    • 0021247950 scopus 로고
    • The contribution of local thyroxine monodeiodination to intracellular 3,5,3′-triiodothyronine in several tissues of hyperthyroid rats at isotopic equilibrium
    • van Doorn J, van der Heide D, Roelfsema F 1984 The contribution of local thyroxine monodeiodination to intracellular 3,5,3′-triiodothyronine in several tissues of hyperthyroid rats at isotopic equilibrium. Endocrinology 115:174-182
    • (1984) Endocrinology , vol.115 , pp. 174-182
    • Van Doorn, J.1    Van Der Heide, D.2    Roelfsema, F.3
  • 21
    • 0021802634 scopus 로고
    • Concentrations of thyroxine and 3,5,3′-triiodothyronine at 34 different sites in euthyroid rats as determined by an isotopic equilibrium technique
    • van Doorn J, Roelfsema F, van der Heide D 1985 Concentrations of thyroxine and 3,5,3′-triiodothyronine at 34 different sites in euthyroid rats as determined by an isotopic equilibrium technique. Endocrinology 117:1201-1208
    • (1985) Endocrinology , vol.117 , pp. 1201-1208
    • Van Doorn, J.1    Roelfsema, F.2    Van Der Heide, D.3
  • 24
    • 0023900392 scopus 로고
    • A multicompartmental model for iodide, thyroxine, and triiodothyronine metabolism in normal and spontaneously hyperthyroid cats
    • Hays MT, Broome MR, Turrel JM 1988 A multicompartmental model for iodide, thyroxine, and triiodothyronine metabolism in normal and spontaneously hyperthyroid cats. Endocrinology 122:2444-2461
    • (1988) Endocrinology , vol.122 , pp. 2444-2461
    • Hays, M.T.1    Broome, M.R.2    Turrel, J.M.3
  • 25
    • 0028255964 scopus 로고
    • Direct measurement of whole body thyroid hormone pool sizes and conversion rates in fasted rats: Hormone regulation implications
    • Yen Y-M, DiStefano III JJ, Yamada H, Nguyen TT 1994 Direct measurement of whole body thyroid hormone pool sizes and conversion rates in fasted rats: hormone regulation implications. Endocrinology 134:1700-1709
    • (1994) Endocrinology , vol.134 , pp. 1700-1709
    • Yen, Y.-M.1    DiStefano III, J.J.2    Yamada, H.3    Nguyen, T.T.4
  • 29
    • 0037954295 scopus 로고
    • Modeling approaches and models of the distribution and disposal of thyroid hormones
    • Hennemann G (ed) Marcel Dekker, New York
    • DiStefano III JJ 1985 Modeling approaches and models of the distribution and disposal of thyroid hormones. In: Hennemann G (ed) Thyroid Hormone Metabolism. Marcel Dekker, New York, pp 39-76
    • (1985) Thyroid Hormone Metabolism , pp. 39-76
    • DiStefano III, J.J.1
  • 30
    • 0019963614 scopus 로고
    • Noncompartmental vs. compartmental modeling: Some bases for choice
    • DiStefano JJ III 1982 Noncompartmental vs. compartmental modeling: some bases for choice. Am J Physiol 243:R1-R6
    • (1982) Am J Physiol , vol.243
    • DiStefano III, J.J.1
  • 31
    • 0021436459 scopus 로고
    • Multiexponential, multicompartmental and noncompartmental modeling: Physiological data analysis and statistical considerations, part I: methodological and physiological interpretations
    • DiStefano JJ III, Landaw EM 1984 Multiexponential, multicompartmental and noncompartmental modeling: physiological data analysis and statistical considerations, part I: methodological and physiological interpretations. Am J Physiol 246:R651-664
    • (1984) Am J Physiol , vol.246
    • DiStefano III, J.J.1    Landaw, E.M.2
  • 32
    • 0023775733 scopus 로고
    • Comparative aspects of the distribution, metabolism and excretion of 6 iodothyronines in the rat
    • DiStefano III JJ and Feng D 1988 Comparative aspects of the distribution, metabolism and excretion of 6 iodothyronines in the rat. Endocrinology 123:2514-2525
    • (1988) Endocrinology , vol.123 , pp. 2514-2525
    • DiStefano III, J.J.1    Feng, D.2
  • 33
    • 0014773678 scopus 로고
    • The peripheral metabolism of triiodothyronine in normal subjects and in patients with hyperthyroidism
    • Woeber KA, Sobel RJ, Ingbar SH, Sterling K 1970 The peripheral metabolism of triiodothyronine in normal subjects and in patients with hyperthyroidism. J Clin Invest 49:643-649
    • (1970) J Clin Invest , vol.49 , pp. 643-649
    • Woeber, K.A.1    Sobel, R.J.2    Ingbar, S.H.3    Sterling, K.4
  • 35
    • 0015605433 scopus 로고
    • The effect of hypothyroidism and thyrotoxicosis on thyroxine metabolism in the rat
    • Cullen MJ, Doherty GF, Ingbar SH 1973 The effect of hypothyroidism and thyrotoxicosis on thyroxine metabolism in the rat. Endocrinology 92:1028-103
    • (1973) Endocrinology , vol.92 , pp. 1028-1103
    • Cullen, M.J.1    Doherty, G.F.2    Ingbar, S.H.3
  • 36
    • 0020160569 scopus 로고
    • Comprehensive kinetics of thyroxine distribution and metabolism in blood and tissue pools of the rat from only six blood samples: Dominance of large, slowly exchanging tissue pools
    • DiStefano III JJ, Malone TK, Jang M 1982 Comprehensive kinetics of thyroxine distribution and metabolism in blood and tissue pools of the rat from only six blood samples: dominance of large, slowly exchanging tissue pools. Endocrinology 111:108-117
    • (1982) Endocrinology , vol.111 , pp. 108-117
    • DiStefano III, J.J.1    Malone, T.K.2    Jang, M.3
  • 39
    • 0021907155 scopus 로고
    • Decrease serum triiodothyronine in starving rat is due primarily to diminish thyroidal secretion of thyroxine
    • Kinlaw WB, Schwartz HL, Oppenheimer JH 1983 Decrease serum triiodothyronine in starving rat is due primarily to diminish thyroidal secretion of thyroxine. J Clin Invest 75:1238-1241
    • (1983) J Clin Invest , vol.75 , pp. 1238-1241
    • Kinlaw, W.B.1    Schwartz, H.L.2    Oppenheimer, J.H.3
  • 40
    • 0015056849 scopus 로고
    • Quantitation of extrathyroidal conversion of L-thyroxine to 3,5,3′-triiodo-E-thyronine in the rat
    • Schwartz HL, Surks MI, Oppenheimer JH 1971 Quantitation of extrathyroidal conversion of L-thyroxine to 3,5,3′-triiodo-E-thyronine in the rat. J Clin Invest 50:1124-1130
    • (1971) J Clin Invest , vol.50 , pp. 1124-1130
    • Schwartz, H.L.1    Surks, M.I.2    Oppenheimer, J.H.3
  • 41
    • 0018843495 scopus 로고
    • Alterations in monodeiodination of iodothyronines in the fasting rat: Effects of reduced nonprotein sulfahydryl groups and hypothyroidism
    • Chopra IJ 1980 Alterations in monodeiodination of iodothyronines in the fasting rat: effects of reduced nonprotein sulfahydryl groups and hypothyroidism. Metabolism 29:161-167
    • (1980) Metabolism , vol.29 , pp. 161-167
    • Chopra, I.J.1
  • 42
    • 0023392224 scopus 로고
    • Role of serum carrier proteins in the peripheral metabolism and tissue distribution of thyroid hormones in familial dysalbuminemic hyperthyroxinemia and congenital elevation of thyroxine-binding globulin
    • Bianchi R, Iervasi G, Pilo A, Vitek F, Fedeghini M, Cazzuola F, Giraudi G 1987 Role of serum carrier proteins in the peripheral metabolism and tissue distribution of thyroid hormones in familial dysalbuminemic hyperthyroxinemia and congenital elevation of thyroxine-binding globulin. J Clin Invest 80:522-534
    • (1987) J Clin Invest , vol.80 , pp. 522-534
    • Bianchi, R.1    Iervasi, G.2    Pilo, A.3    Vitek, F.4    Fedeghini, M.5    Cazzuola, F.6    Giraudi, G.7
  • 43
    • 0017650132 scopus 로고
    • Pituitary nuclear 3,5,3′-triiodothyronine and thyrotropin: An explanation for the effect of thyroxine
    • Silva JE, Larsen PR 1977 Pituitary nuclear 3,5,3′-triiodothyronine and thyrotropin: an explanation for the effect of thyroxine. Science 198:617-619
    • (1977) Science , vol.198 , pp. 617-619
    • Silva, J.E.1    Larsen, P.R.2
  • 44
    • 0017618522 scopus 로고
    • Comparison of the biological effects of thyroxine and triiodothyronine in the rat
    • Larsen PR, Frumess RD 1977 Comparison of the biological effects of thyroxine and triiodothyronine in the rat. Endocrinology 100:980-988
    • (1977) Endocrinology , vol.100 , pp. 980-988
    • Larsen, P.R.1    Frumess, R.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.