Evaluation of the early processing routes of N-linked oligosaccharides of glycoproteins through the characterization of Man8GlcNAc2 isomers: Evidence that endomannosidase functions in vivo in the absence of a glucosidase blockade

Glycobiology

Volumn 6, Issue 8, 1996, Pages 861-868

  Weng, Shuai ^a   Spiro, Robert G ^a  

^a JOSLIN DIABETES CENTER   (United States)

Author keywords

Endomannosidase; Glycoprotein processing; Kifunensine; Man8GlcNAc2 isomers; Mannosidase

Indexed keywords

KIFUNENSINE; MANNOSIDASE;

ANIMAL CELL; ARTICLE; CARBOHYDRATE SYNTHESIS; CELL CULTURE; CELL STRAIN HEPG2; CELL STRAIN HL 60; CONTROLLED STUDY; DOG; ENZYME ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; KIDNEY CELL; LIVER CELL; LYMPHOMA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; STEREOCHEMISTRY; THIN LAYER CHROMATOGRAPHY;

ACETYLGLUCOSAMINE; ANIMALS; DOGS; GLYCOPROTEINS; HUMANS; ISOMERISM; MANNOSE; MANNOSIDASES; OLIGOSACCHARIDES; PROTEIN PROCESSING, POST-TRANSLATIONAL; TUMOR CELLS, CULTURED;

EID: 0030445531     PISSN: 09596658     EISSN: None     Source Type: Journal    
DOI: 10.1093/glycob/6.8.861     Document Type: Review

References (28)

1. Bischoff, J. and Kornfeld, R. (1983) Evidence for an α-mannosidase in endoplasmic reticulum of rat liver. J. Biol. Chem., 258, 7907-7910.
2. Daniel, P.F., Winchester, B. and Warren, C.D. (1994) Mammalian α-mannosidases - multiple forms but a common purpose? Glycobiology, 4, 551-566.
3. Elbein, A.D., Tropea, J.E., Mitchell, M. and Kaushal, G.P. (1990) Kifunensine, a potent inhibitor of the glycoprotein processing mannosidase I. J. Biol. Chem., 265, 15599-15605.
4. Godelaine, D., Spiro, M.J. and Spiro, R.G. (1981) Processing of the carbohydrate units of thyroglobulin. J. Biol. Chem., 256, 10161-10168.
5. Grinna, L.S. and Robbins, P.W. (1980) Substrate specificities of rat liver microsomol glucosidases which process glycoproteins. J. Biol. Chem., 255, 2255-2258.
6. Hase, S., Ibuki, T. and Ikenaka, T. (1984) Re-examination of the pyridylamination used for fluorescence labeling of oligosaccharides and its application to glycoproteins. J. Biochem. (Tokyo), 95, 197-203.
7. Hickman, S., Theodorakis, J.L., Greco, J.M. and Brown, P.H. (1984) Processing of MOPC 315 immunoglobin A oligosaccharides: evidence for the endoplasmic reticulum and trans Golgi α1,2 -mannosidase activity. J. Cell Biol., 98, 407-416.
8. Hiraizumi, S , Spohr, U. and Spiro, R.G. (1993) Characterization of endomannosidase inhibitors and evaluation of their effect on N-linked oligosaccharide processing during glycoprotein biosynthesis. J. Biol. Chem., 268, 9927-9935
9. Kabcenell, A.K. and Atkinson, P.H. (1985) Processing of the rough endoplasmic reticulum membrane glycoproteins of rotavirus SA11. J. Cell Biol., 101, 1270-1280.
10. Knowles, B.B., Howe, C.C. and Aden, D.P. (1980) Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen Science, 209, 497-499.
11. Leelavathi, D.E., Estes, L.W., Feingold, D.S. and Lombardi, B. (1970) Isolation of a Golgi- rich fraction from rat liver Biochim. Biophys. Acta, 211, 124-138.
12. Lewis, M.J., Turco, S.J. and Green, M. (1985) Structure and assembly of the endoplasmic reticulum. Biosynthetic sorting of endoplasmic reticulum proteins. J. Biol. Chem., 260, 6926-6931.
13. Lubas, W A., and Spiro, R.G. (1987) Golgi endo-α-mannosidase from rat liver, a novel N-linked carbohyrate unit processing enzyme. J. Biol. Chem., 262, 3775-3781.
14. Lubas, W.A. and Spiro, R.G. (1988) Evaluation of the role of rat liver Golgi endo-α-D-mannosidase in processing N-linked oligosaccharides. J. Biol. Chem., 263, 3990-3998.
15. Moore, S.E.H., and Spiro, R.G. (1990) Demonstration that Golgi endo-α-D-mannosidase provides a glucosidase-independent pathway for the formation of complex N-linked oligosaccharides of glycoproteins. J. Biol. Chem., 265, 13104-13112.
16. Moremen, K.W., Trimble, R.B. and Herscovics, A. (1994) Glycosidases of the asparagine-linked oligosaccharide processing pathway. Glycobiology, 4, 113-125.
17. Peterson, G.L. (1977) A simplification of the protein assay method of Lowry et al. which is more generally applicable. Anal. Biochem., 83, 346-356.
18. Rabouille, C. and Spiro, R.G. (1992) Nonselective utilization of the endomannosidase pathway for processing glycoproteins by human hepatoma (HepG2) cells. J. Biol. Chem., 261, 11573-11578.
19. Rosenfeld, M.G., Marcantonio, E.E., Hakimi, J., Ort, V.M., Atkinson, P., Sabatini, D., and Kreibich, G. (1984) Biosynthesis and processing of ribophorin in the endoplasmic reticulum. J. Cell Biol., 99, 1076-1082.
20. Spiro, M.J. and Spiro, R.G. (1985) Effect of anion-specific inhibitors on the utilization of sugar nucleotides for N-linked carbohydrate unit assembly by thyroid endoplasmic reticulum vesicles. J. Biol. Chem , 260, 5808-5815.
21. Spiro, M.J., Spiro, R.G. and Bhoyroo, V.D. (1976) Lipid-saccharide intermediates in glycoprotein biosynthesis. I. Formation of an oligosaccharide-lipid by thyroid slices and evaluation of its role in protein glycosylation. J. Biol. Chem., 251, 6400-6408.
22. Spiro, R.G., Zhu, Q., Bhoyroo, V. and Soling, H.D. (1996) Definition of the lectin-like properties of the molecular chaperone, calreticulin, and demonstration of its copurification with endomannosidase from rat liver Golgi. J. Biol. Chem , 271, 11588-11594.
23. Tulsiani, D.R.P., Opheim, D.J. and Touster, O. (1977) Purification and characterization of α-mannosidase from rat liver Golgi membranes. J. Biol. Chem., 252, 3227-3233.
24. Tulsiani, D.R.P. and Touster, O. (1988) The purification and characterization of mannosidase IA from rat liver Golgi membranes. J. Biol. Chem., 263, 5408-5417.
25. Varki, A. and Kornfeld, S. (1983) The spectrum of anionic oligosaccharides released by endo-β-N-acetylglucosominidase H from glycoproteins. Structural studies and interactions with the phosphomannosyl receptor J. Biol. Chem., 258, 2808-2818.
26. Velasco, A., Hendricks, L., Moremen, K.W., Tulsiani, D.R.P., Touster, O. and Farquhar, M.G. (1993) Cell type-dependent variations in the subcellular distribution of α-mannosidase I and II. J. Cell Biol., 122, 39-51.
27. Weng, S. and Spiro, R.G. (1993) Demonstration that a kifunensine-resistant α-mannosidase with a unique action on N-linked oligosaccharides occurs in rat liver endoplasmic reticulum and various cultured cells. J. Biol. Chem., 268, 25656-25663.
28. Weng, S. and Spiro, R.G. (1996) Endoplasmic reticulum kifunensine-resistant α-mannosidase is enzymatically and immunalogically related to the cytosolic α-mannosidase. Arch. Biochem. Biophys., 325, 113-123.