-
1
-
-
0026316096
-
Growth factors and cancer
-
S. A. AARONSON, Growth factors and cancer, Science 254, 1146-1153 (1991).
-
(1991)
Science
, vol.254
, pp. 1146-1153
-
-
Aaronson, S.A.1
-
2
-
-
0027318445
-
Cancer progression and growth: Relationship of paracrine and autocrine growth mechanisms to organ preference of metastasis
-
G. L. NICOLSON, Cancer progression and growth: relationship of paracrine and autocrine growth mechanisms to organ preference of metastasis, Exptl. Cell. Res. 204, 171-180 (1993).
-
(1993)
Exptl. Cell. Res.
, vol.204
, pp. 171-180
-
-
Nicolson, G.L.1
-
3
-
-
0026010995
-
Molecular themes in oncogenesis
-
J. M. BISHOP, Molecular themes in oncogenesis, Cell 64, 235-248 (1991).
-
(1991)
Cell
, vol.64
, pp. 235-248
-
-
Bishop, J.M.1
-
4
-
-
0026069474
-
Oncogenes and signal transduction
-
L. C. LANTLEY, K. R. AUGER, C. CARPENTER, B. DUCKWORTH, A. BRAZIANI, R. KAPELLER and S. SOLTOFF, Oncogenes and signal transduction, Cell 64, 281-302 (1991).
-
(1991)
Cell
, vol.64
, pp. 281-302
-
-
Lantley, L.C.1
Auger, K.R.2
Carpenter, C.3
Duckworth, B.4
Braziani, A.5
Kapeller, R.6
Soltoff, S.7
-
5
-
-
0027536907
-
Cell-signaling targets for antitumor drug development
-
V. G. BRUNTON and P. WORKMAN, Cell-signaling targets for antitumor drug development, Cancer Chemother. Pharmacol. 32, 1-19 (1993).
-
(1993)
Cancer Chemother. Pharmacol.
, vol.32
, pp. 1-19
-
-
Brunton, V.G.1
Workman, P.2
-
6
-
-
0142050676
-
The potential for molecular oncology to define new drug targets
-
(P. WORKMAN and D. J. KERR, eds.), Boca Raton L., CRC Press
-
G. POWIS, The potential for molecular oncology to define new drug targets, pp. 1-29 in New Molecular Targets for Cancer Chemotherapy. (P. WORKMAN and D. J. KERR, eds.), Boca Raton L., CRC Press (1994).
-
(1994)
New Molecular Targets for Cancer Chemotherapy
, pp. 1-29
-
-
Powis, G.1
-
7
-
-
0028000069
-
Signal-transduction therapy. A novel approach to disease management
-
A. LEVITZKI, Signal-transduction therapy. A novel approach to disease management, Eur. J. Biochem. 226, 1-13 (1994).
-
(1994)
Eur. J. Biochem.
, vol.226
, pp. 1-13
-
-
Levitzki, A.1
-
8
-
-
0026335802
-
Inhibitory effect of bombesin/gastrin-releasing peptide antagonist RC-3095 and high dose of somatostatin analogue RC-160 on nitrosamine-induced pancreatic cancers in hamsters
-
K. SZEPESHAZI, A. V. SCHALLY, R. Z. CAI, S. RADULOVIC, S. MILOVANOVIC and B. SZOKE, Inhibitory effect of bombesin/gastrin-releasing peptide antagonist RC-3095 and high dose of somatostatin analogue RC-160 on nitrosamine-induced pancreatic cancers in hamsters, Cancer Res. 51, 5980-5986 (1991).
-
(1991)
Cancer Res.
, vol.51
, pp. 5980-5986
-
-
Szepeshazi, K.1
Schally, A.V.2
Cai, R.Z.3
Radulovic, S.4
Milovanovic, S.5
Szoke, B.6
-
9
-
-
0027052939
-
Growth inhibition of estrogen-dependent and estrogen-independent MXT mammary cancers in mice by the bombesin and gastrin-releasing peptide antagonist RC-3095
-
K. SZEPESHAZI, A. V. SCHALLY, G. HALMOS, K. GROOT and S. RADULOVIC, Growth inhibition of estrogen-dependent and estrogen-independent MXT mammary cancers in mice by the bombesin and gastrin-releasing peptide antagonist RC-3095, J. Natl. Cancer. Inst. 84, 1915-1922 (1992).
-
(1992)
J. Natl. Cancer. Inst.
, vol.84
, pp. 1915-1922
-
-
Szepeshazi, K.1
Schally, A.V.2
Halmos, G.3
Groot, K.4
Radulovic, S.5
-
10
-
-
0026752724
-
Inhibition of growth of PC-82 human prostate cancer line xenografts in nude mice by bombesin antagonist RC-3095 or combination of agonist [D-Trp6]-luteinizing hormone-releasing hormone and somatostatin analog RC-160
-
S. MILOVANOVIC, S. RADULOVIC, K. GROOT and A. V. SCHALLY, Inhibition of growth of PC-82 human prostate cancer line xenografts in nude mice by bombesin antagonist RC-3095 or combination of agonist [D-Trp6]-luteinizing hormone-releasing hormone and somatostatin analog RC-160, Prostate 20, 269-280 (1992).
-
(1992)
Prostate
, vol.20
, pp. 269-280
-
-
Milovanovic, S.1
Radulovic, S.2
Groot, K.3
Schally, A.V.4
-
11
-
-
0025297203
-
Suramin: A new therapeutic concept
-
J. P. ARMAND and E. CVITKOVIC, Suramin: A new therapeutic concept, Eur. J. Cancer 26, 417-419 (1990).
-
(1990)
Eur. J. Cancer
, vol.26
, pp. 417-419
-
-
Armand, J.P.1
Cvitkovic, E.2
-
12
-
-
0024593227
-
Suramin: An anticancer drug with a unique mechanism of action
-
C. A. STEIN, R. V. LAROCCA, R. THOMAS, N. McATEE and C. E. MYERS, Suramin: An anticancer drug with a unique mechanism of action, J. Clin. Oncol. 7, 499-508 (1989).
-
(1989)
J. Clin. Oncol.
, vol.7
, pp. 499-508
-
-
Stein, C.A.1
Larocca, R.V.2
Thomas, R.3
McAtee, N.4
Myers, C.E.5
-
13
-
-
0027471478
-
Suramin, an active drug for prostate cancer: Interim observations in a phase I trial
-
M. A. EISENBERGER, L. M. REYNO, D. I. JODRELL, V. J. SINIBALDI, K. H. TKACZUK, R. SRIDHARA, E. G. ZUHOWSKI, M. H. LOWITT, S. C. JACOBS and M. J. EGORIN, Suramin, an active drug for prostate cancer: interim observations in a phase I trial, J. Natl. Cancer Inst. 85, 611-621 (1993).
-
(1993)
J. Natl. Cancer Inst.
, vol.85
, pp. 611-621
-
-
Eisenberger, M.A.1
Reyno, L.M.2
Jodrell, D.I.3
Sinibaldi, V.J.4
Tkaczuk, K.H.5
Sridhara, R.6
Zuhowski, E.G.7
Lowitt, M.H.8
Jacobs, S.C.9
Egorin, M.J.10
-
14
-
-
0026517614
-
Suramin, an active nonhormonal cytotoxic drug for treatment of prostate cancer: Compelling reasons for testing in patients with hormone refractory breast cancer
-
M. A. EISENBERGER and J. A. FONTANA, Suramin, an active nonhormonal cytotoxic drug for treatment of prostate cancer: compelling reasons for testing in patients with hormone refractory breast cancer, J. Natl. Cancer Inst. 84, 3-5 (1992).
-
(1992)
J. Natl. Cancer Inst.
, vol.84
, pp. 3-5
-
-
Eisenberger, M.A.1
Fontana, J.A.2
-
15
-
-
0026426157
-
Phase I and imaging trial of indium 111-labeled anti-epidermal growth factor receptor monoclonal antibody 225 in patients with squamous cell lung carcinoma
-
C. R. DIVGI, S. WELT, M. KRIS, F. X. REAL, S. D. YEH, R. GRALLA, B. MERCHANT, S. SCHWEIGHAR, M. UNGER and S. M. LARSON, Phase I and imaging trial of indium 111-labeled anti-epidermal growth factor receptor monoclonal antibody 225 in patients with squamous cell lung carcinoma, J. Natl. Cancer Inst. 83, 97-104 (1991).
-
(1991)
J. Natl. Cancer Inst.
, vol.83
, pp. 97-104
-
-
Divgi, C.R.1
Welt, S.2
Kris, M.3
Real, F.X.4
Yeh, S.D.5
Gralla, R.6
Merchant, B.7
Schweighar, S.8
Unger, M.9
Larson, S.M.10
-
16
-
-
0026486446
-
Selective inhibition of tumor cell growth by a recombinant single-chain antibody-toxin specific for the erbB-2 receptor
-
W. WELS, I. M. HARWERTH, M. MUELLER, B. GRONER and N. E. HYNES, Selective inhibition of tumor cell growth by a recombinant single-chain antibody-toxin specific for the erbB-2 receptor, Cancer Res. 52, 6310-6317 (1992).
-
(1992)
Cancer Res.
, vol.52
, pp. 6310-6317
-
-
Wels, W.1
Harwerth, I.M.2
Mueller, M.3
Groner, B.4
Hynes, N.E.5
-
17
-
-
0026458235
-
Tyrphostins: Tyrosine kinase blockers as novel antiproliferative agents and dissectors of signal transduction
-
A. LEVITZKI, Tyrphostins: tyrosine kinase blockers as novel antiproliferative agents and dissectors of signal transduction, FASEB J. 6, 3275-3282 (1992).
-
(1992)
FASEB J.
, vol.6
, pp. 3275-3282
-
-
Levitzki, A.1
-
18
-
-
0343825554
-
Discovery and design of inhibitors of oncogenic tyrosine kinases
-
(P. WORKMAN, ed.) Springer, Berlin
-
P. WORKMAN, V. G. BRUNTON and D. J. ROBINS, Discovery and design of inhibitors of oncogenic tyrosine kinases, pp. 55-70 in New Approaches in Cancer Pharmacology: Drug Design and Development (P. WORKMAN, ed.) Springer, Berlin (1994).
-
(1994)
New Approaches in Cancer Pharmacology: Drug Design and Development
, pp. 55-70
-
-
Workman, P.1
Brunton, V.G.2
Robins, D.J.3
-
19
-
-
0028180234
-
4,5-Dianilinophthalimide: A protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitumor activity
-
E. BUCHDUNGER, U. TRINKS, H. METT, U. REGENASS, M. MULLER, T. MEYER, E. McGLYNN, L. A. PINNA, P. TRAXLER and N. B. LYDON, 4,5-Dianilinophthalimide: a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitumor activity, Proc. Natl. Acad. Sci. U.S.A 91, 2334-2338 (1994).
-
(1994)
Proc. Natl. Acad. Sci. U.S.A
, vol.91
, pp. 2334-2338
-
-
Buchdunger, E.1
Trinks, U.2
Mett, H.3
Regenass, U.4
Muller, M.5
Meyer, T.6
McGlynn, E.7
Pinna, L.A.8
Traxler, P.9
Lydon, N.B.10
-
20
-
-
0024552224
-
Effects of activators of protein kinase C, including bryostatins 1 and 2, on the growth of A549 human lung carcinoma cell
-
I. L. DALE and A. GESCHER, Effects of activators of protein kinase C, including bryostatins 1 and 2, on the growth of A549 human lung carcinoma cell, Int. J. Cancer 43, 158-163 (1989).
-
(1989)
Int. J. Cancer
, vol.43
, pp. 158-163
-
-
Dale, I.L.1
Gescher, A.2
-
22
-
-
0024379951
-
A derivative of staurosporine (CGP 41251) shows selectivity for protein kinase C inhibition and in vitro anti-proliferative as well as in vivo anti-tumor activity
-
T. MEYER, U. REGENASS, D. FABBRO, E. ALTERI, J. ROSEL, M. MULLER, G. CARAVATTI and A. MATTER, A derivative of staurosporine (CGP 41251) shows selectivity for protein kinase C inhibition and in vitro anti-proliferative as well as in vivo anti-tumor activity, Int. J. Cancer 43, 851-856 (1989).
-
(1989)
Int. J. Cancer
, vol.43
, pp. 851-856
-
-
Meyer, T.1
Regenass, U.2
Fabbro, D.3
Alteri, E.4
Rosel, J.5
Muller, M.6
Caravatti, G.7
Matter, A.8
-
23
-
-
0027016222
-
Involvement of protein kinase C in the growth regulation of human breast cancer cells
-
D. FABBRO, W. KUNG, S. D. COSTA, C. BORNER, U. REGENASS and U. EPPENBERGER, Involvement of protein kinase C in the growth regulation of human breast cancer cells, Cancer Treat. Res. 61, 229-248 (1992).
-
(1992)
Cancer Treat. Res.
, vol.61
, pp. 229-248
-
-
Fabbro, D.1
Kung, W.2
Costa, S.D.3
Borner, C.4
Regenass, U.5
Eppenberger, U.6
-
24
-
-
0027435064
-
The potential of protein kinase C as a target for anticancer treatment
-
A. BASU, The potential of protein kinase C as a target for anticancer treatment, Pharmacol. Ther. 59, 257-280 (1993).
-
(1993)
Pharmacol. Ther.
, vol.59
, pp. 257-280
-
-
Basu, A.1
-
25
-
-
0027274935
-
Inhibition of binding of phospholipase C gamma 1 SH2 domains to phosphorylated epidermal growth factor receptor by phosphorylated peptides
-
D. J. McNAMARA, E. M. DOBRUSIN, G. ZHU, S. J. DECKER and A. R. SALTIEL, Inhibition of binding of phospholipase C gamma 1 SH2 domains to phosphorylated epidermal growth factor receptor by phosphorylated peptides, Int. J. Pept. Protein Res. 42, 240-248 (1993).
-
(1993)
Int. J. Pept. Protein Res.
, vol.42
, pp. 240-248
-
-
McNamara, D.J.1
Dobrusin, E.M.2
Zhu, G.3
Decker, S.J.4
Saltiel, A.R.5
-
26
-
-
0028130221
-
Peptide inhibitors of src SH3-SH2-phosphoprotein interaction
-
T. GILMER, M. RODRIGUES, S. JORDAN, R. CROSBY, K. ALLIGOOD, M. GREEN, M. KIMERY, C. WAGNER, D. KINDER and P. CHARIFSON, Peptide inhibitors of src SH3-SH2-phosphoprotein interaction, J. Biol. Chem. 269, 31711-31719 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 31711-31719
-
-
Gilmer, T.1
Rodrigues, M.2
Jordan, S.3
Crosby, R.4
Alligood, K.5
Green, M.6
Kimery, M.7
Wagner, C.8
Kinder, D.9
Charifson, P.10
-
27
-
-
0027996649
-
Suppression of H-ras-mediated transformation in NIH 3T3 cells by a ras ribozyme
-
T. FUNATO, T. SHITARA, T. TONE, L. JIAO, M. KASHANI-SABET and K. J. SCANLON, Suppression of H-ras-mediated transformation in NIH 3T3 cells by a ras ribozyme, Biochem. Pharmacol. 48, 1471-1475 (1994).
-
(1994)
Biochem. Pharmacol.
, vol.48
, pp. 1471-1475
-
-
Funato, T.1
Shitara, T.2
Tone, T.3
Jiao, L.4
Kashani-Sabet, M.5
Scanlon, K.J.6
-
28
-
-
0025736802
-
Short modified antisense oligonucleotides directed against Ha-ras point mutation induce selective cleavage of the mRNA and inhibit T24 cells proliferation
-
T. SAISON BEHMOARAS, B. TOCQUE, I. REY, M. CHASSIGNOL, N. T. THUONG and C. HELENE, Short modified antisense oligonucleotides directed against Ha-ras point mutation induce selective cleavage of the mRNA and inhibit T24 cells proliferation, EMBO J. 10, 1111-1118 (1991).
-
(1991)
EMBO J.
, vol.10
, pp. 1111-1118
-
-
Behmoaras, T.S.1
Tocque, B.2
Rey, I.3
Chassignol, M.4
Thuong, N.T.5
Helene, C.6
-
29
-
-
0025868669
-
Specific inhibition of K-ras expression and tumorigenicity of lung cancer cells by antisense RNA
-
T. MUKHOPADHYAY, M. TAINSKY, A. CAVENDER and J. A. ROTH, Specific inhibition of K-ras expression and tumorigenicity of lung cancer cells by antisense RNA, Cancer Res. 51, 1744-1748 (1991).
-
(1991)
Cancer Res.
, vol.51
, pp. 1744-1748
-
-
Mukhopadhyay, T.1
Tainsky, M.2
Cavender, A.3
Roth, J.A.4
-
30
-
-
0028331587
-
Farnesyl-transferase inhibitors: Ras research yields a potential cancer therapeutic
-
J. B. GIBBS, A. OLIFF and N. E. KOHL, Farnesyl-transferase inhibitors: Ras research yields a potential cancer therapeutic, Cell 77, 175-178 (1994).
-
(1994)
Cell
, vol.77
, pp. 175-178
-
-
Gibbs, J.B.1
Oliff, A.2
Kohl, N.E.3
-
31
-
-
0028343655
-
Structure-activity relationships among monoterpene inhibitors of protein isoprenylation and cell proliferation
-
P. L. CROWELL, Z. REN, S. LIN, E. VEDEJS and M. N. GOULD, Structure-activity relationships among monoterpene inhibitors of protein isoprenylation and cell proliferation, Biochem. Pharmacol. 47, 1405-1415 (1994).
-
(1994)
Biochem. Pharmacol.
, vol.47
, pp. 1405-1415
-
-
Crowell, P.L.1
Ren, Z.2
Lin, S.3
Vedejs, E.4
Gould, M.N.5
-
32
-
-
0028912593
-
A non-peptide mimetic of Ras-CAAX: Selective inhibition of farnesyltransferase and ras processing
-
A. VOGT, Y. QUIANS, M. A. BLASKOVICH, R. D. FOSSUM, A. D. HAMILTON and S. M. SEBTI, A non-peptide mimetic of Ras-CAAX: selective inhibition of farnesyltransferase and ras processing, J. Biol. Chem. 270, 660-664 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 660-664
-
-
Vogt, A.1
Quians, Y.2
Blaskovich, M.A.3
Fossum, R.D.4
Hamilton, A.D.5
Sebti, S.M.6
-
33
-
-
0026624967
-
Inhibition of cancer cell growth by calcium channel antagonists in the athymic mouse
-
J. M. TAYLOR and R. U. SIMPSON, Inhibition of cancer cell growth by calcium channel antagonists in the athymic mouse, Cancer Res. 52, 2413-2418 (1992).
-
(1992)
Cancer Res.
, vol.52
, pp. 2413-2418
-
-
Taylor, J.M.1
Simpson, R.U.2
-
34
-
-
0028205812
-
Structure function analysis of signal and growth inhibition by carboxyamidotriazole, CAI
-
E. C. KOHN, C. C. FELDER, W. JACOBS, K. A. HOLMES, A. DAY, R. FREER and L. A. LIOTTA, Structure function analysis of signal and growth inhibition by carboxyamidotriazole, CAI, Cancer Res. 54, 935-942 (1994).
-
(1994)
Cancer Res.
, vol.54
, pp. 935-942
-
-
Kohn, E.C.1
Felder, C.C.2
Jacobs, W.3
Holmes, K.A.4
Day, A.5
Freer, R.6
Liotta, L.A.7
-
35
-
-
0026740712
-
In vivo efficacy of a novel inhibitor of selected signal-transduction pathways including calcium, arachidonate, and inositol phosphates
-
E. K. KOHN, M. A. SANDEEN and L. A. LIOTTA, In vivo efficacy of a novel inhibitor of selected signal-transduction pathways including calcium, arachidonate, and inositol phosphates, Cancer Res. 52, 3208-3212 (1992).
-
(1992)
Cancer Res.
, vol.52
, pp. 3208-3212
-
-
Kohn, E.K.1
Sandeen, M.A.2
Liotta, L.A.3
-
36
-
-
0026742177
-
Selective inhibition of phosphatidylinositol phospholipase C by cytotoxic ether lipid analogues
-
G. POWIS, M. J. SEEWALD, C. GRATAS, D. MELDER, J. RIEBOW and E. J. MODEST, Selective inhibition of phosphatidylinositol phospholipase C by cytotoxic ether lipid analogues, Cancer Res. 52, 2835-2840 (1992).
-
(1992)
Cancer Res.
, vol.52
, pp. 2835-2840
-
-
Powis, G.1
Seewald, M.J.2
Gratas, C.3
Melder, D.4
Riebow, J.5
Modest, E.J.6
-
37
-
-
0025963780
-
Hexadecylphosphocholine inhibits inositol phosphate formation and protein kinase C activity
-
F. ÜBERALL, H. OBERHUBER, K. MALY, J. ZAKNUN, L. DEMUTH and H. H. GRUNICKE, Hexadecylphosphocholine inhibits inositol phosphate formation and protein kinase C activity, Cancer Res. 51, 807-812 (1991).
-
(1991)
Cancer Res.
, vol.51
, pp. 807-812
-
-
Überall, F.1
Oberhuber, H.2
Maly, K.3
Zaknun, J.4
Demuth, L.5
Grunicke, H.H.6
-
38
-
-
0029161730
-
Interference of new alkylphospholipid analogues with mitogenic signal transduction
-
K. MALY, F. ÜBERALL, C. SCHUBERT, E. KINDLER, J. STEKAR, H. BRACHWITZ and H. H. GRUNICKE, Interference of new alkylphospholipid analogues with mitogenic signal transduction, Anti Cancer Drug Design 10, 411-425 (1995).
-
(1995)
Anti Cancer Drug Design
, vol.10
, pp. 411-425
-
-
Maly, K.1
Überall, F.2
Schubert, C.3
Kindler, E.4
Stekar, J.5
Brachwitz, H.6
Grunicke, H.H.7
-
39
-
-
0342954535
-
Inhibition of phospholipase C and cell growth by ether lipid analogues of phosphatidylinositol
-
F. W. PERELLA, C. PIANTADOSE, C. J. MARASCO and E. J. MODEST, Inhibition of phospholipase C and cell growth by ether lipid analogues of phosphatidylinositol, Proc. Am. Assoc. Cancer Res. 31, 409 (1990).
-
(1990)
Proc. Am. Assoc. Cancer Res.
, vol.31
, pp. 409
-
-
Perella, F.W.1
Piantadose, C.2
Marasco, C.J.3
Modest, E.J.4
-
40
-
-
0025989557
-
D-3-deoxy-3-substituted myo-inositol analogues as inhibitors of cell growth
-
G. POWIS, I. A. AKSOY, D. C. MELDER, S. AKSOY, H. EICHINGER, A. H. FAUQ and A. P. KOZIKOWSKI, D-3-Deoxy-3-substituted myo-inositol analogues as inhibitors of cell growth, Cancer Chemother. Pharmacol. 29, 95-104 (1991).
-
(1991)
Cancer Chemother. Pharmacol.
, vol.29
, pp. 95-104
-
-
Powis, G.1
Aksoy, I.A.2
Melder, D.C.3
Aksoy, S.4
Eichinger, H.5
Fauq, A.H.6
Kozikowski, A.P.7
-
41
-
-
0028217223
-
Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase
-
G. POWIS, R. BONJOUKLIAN, M. M. BERGGREN, A. GALLEGOS, R. ABRAHAM, C. ASHENDEL, L. ZALKOW, W. F. MATTER, J. DODGE and G. GRINDEY, Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase, Cancer Res. 54, 2419-2423 (1994).
-
(1994)
Cancer Res.
, vol.54
, pp. 2419-2423
-
-
Powis, G.1
Bonjouklian, R.2
Berggren, M.M.3
Gallegos, A.4
Abraham, R.5
Ashendel, C.6
Zalkow, L.7
Matter, W.F.8
Dodge, J.9
Grindey, G.10
-
42
-
-
0028170210
-
A specific inhibitor of phosphatidyl-inositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
-
C. J. VLAHOS, W. F. MATTER, K. Y. HUI and R. F. BROWN, A specific inhibitor of phosphatidyl-inositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J. Biol. Chem. 269, 5241-5248 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 5241-5248
-
-
Vlahos, C.J.1
Matter, W.F.2
Hui, K.Y.3
Brown, R.F.4
-
43
-
-
0027250493
-
Activation of the cryptic DNA binding function of mutant forms of p53
-
T. R. HUPP, D. W. MEEK, C. A. MIDGLEY and D. P. LANE, Activation of the cryptic DNA binding function of mutant forms of p53, Nucleic Acids Res. 21, 3167-3174 (1993).
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 3167-3174
-
-
Hupp, T.R.1
Meek, D.W.2
Midgley, C.A.3
Lane, D.P.4
-
44
-
-
0027983669
-
Crystal structure of a p53 tumor suppressor-DNA complex: Understanding tumorigenic mutations
-
Y. CHO, S. GORINA, P. D. JEFFREY and N. P. PAVLETICH, Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations, Science 265, 346-355 (1994).
-
(1994)
Science
, vol.265
, pp. 346-355
-
-
Cho, Y.1
Gorina, S.2
Jeffrey, P.D.3
Pavletich, N.P.4
-
45
-
-
0018573286
-
Alykllysophospholipid induced suppression of human lymphocyte response to mitogens and selective killing of lymphoblasts
-
R. ANDREESEN, M. MODOLELL, H. U. WELTZIEN and P. G. MUNDER, Alykllysophospholipid induced suppression of human lymphocyte response to mitogens and selective killing of lymphoblasts, Immunobiol. 156, 498 (1979).
-
(1979)
Immunobiol.
, vol.156
, pp. 498
-
-
Andreesen, R.1
Modolell, M.2
Weltzien, H.U.3
Munder, P.G.4
-
46
-
-
0021356708
-
Tumor cytotoxicity of human macrophages after incubation with synthetic analogs of 2-lysophosphatidylcholine
-
R. ANDREESEN, J. OSTERHOLZ, G. A. LUCKENBACH, U. COSTABEL, A. SCHULZ, V. SPETH, P. G. MUNDER and G. W. LÖHR, Tumor cytotoxicity of human macrophages after incubation with synthetic analogs of 2-lysophosphatidylcholine, J. Natl. Cancer Inst. 72, 53-59 (1984).
-
(1984)
J. Natl. Cancer Inst.
, vol.72
, pp. 53-59
-
-
Andreesen, R.1
Osterholz, J.2
Luckenbach, G.A.3
Costabel, U.4
Schulz, A.5
Speth, V.6
Munder, P.G.7
Löhr, G.W.8
-
47
-
-
0025861450
-
Membrane-interactive lipids as experimental anticancer drugs
-
W. E. BERDEL, Membrane-interactive lipids as experimental anticancer drugs, British J. Cancer 64, 208 (1991).
-
(1991)
British J. Cancer
, vol.64
, pp. 208
-
-
Berdel, W.E.1
-
48
-
-
0027241784
-
Alkylphosphocholines: A new class of membrane-active anticancer agents
-
P. HILGARD, T. KLENNER, J. STEKAR and C. UNGER, Alkylphosphocholines: a new class of membrane-active anticancer agents, Cancer Chemother. Pharmacol. 32, 90 (1993).
-
(1993)
Cancer Chemother. Pharmacol.
, vol.32
, pp. 90
-
-
Hilgard, P.1
Klenner, T.2
Stekar, J.3
Unger, C.4
-
49
-
-
0024412493
-
The protein kinase C family: Heterogeneity and its implications
-
U. KIKKAWA, A. KISHIMOTO and Y. NISHIZUKA, The protein kinase C family: heterogeneity and its implications, Annu. Rev. Biochem. 58, 31-44 (1989).
-
(1989)
Annu. Rev. Biochem.
, vol.58
, pp. 31-44
-
-
Kikkawa, U.1
Kishimoto, A.2
Nishizuka, Y.3
-
51
-
-
0028492597
-
Protein kinase C - An enzyme and its relatives
-
S. STABEL, Protein kinase C - an enzyme and its relatives, Cancer Biol. 5, 277-284 (1994).
-
(1994)
Cancer Biol.
, vol.5
, pp. 277-284
-
-
Stabel, S.1
-
52
-
-
0026451081
-
Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C
-
Y. NISHIZUKA, Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C, Science 258, 607-614 (1992).
-
(1992)
Science
, vol.258
, pp. 607-614
-
-
Nishizuka, Y.1
-
53
-
-
0027322679
-
Protein kinase C isoenzymes: Divergence in signal transduction?
-
H. HUG and T. F. SARRE, Protein kinase C isoenzymes: divergence in signal transduction? Biochem. J. 291, 329-343 (1993).
-
(1993)
Biochem. J.
, vol.291
, pp. 329-343
-
-
Hug, H.1
Sarre, T.F.2
-
54
-
-
0027182090
-
The epsilon isoform of protein kinase C is an oncogene when overexpressed in rat fibroblasts
-
A. M. CACACE, S. N. GUADAGNO, R. S. KRAUSS, D. FABBRO and I. B. WEINSTEIN, The epsilon isoform of protein kinase C is an oncogene when overexpressed in rat fibroblasts, Oncogene 8, 2095-2104 (1993).
-
(1993)
Oncogene
, vol.8
, pp. 2095-2104
-
-
Cacace, A.M.1
Guadagno, S.N.2
Krauss, R.S.3
Fabbro, D.4
Weinstein, I.B.5
-
55
-
-
0027178812
-
Protein kinase C zeta isoform is critical for mitogenic signal transduction
-
E. BERRA, M. T. DIAZ MECO, I. DOMINGUEZ, M. M. MUNICIO, L. SANZ, J. LOZANO, R. S. CHAPKIN and J. MOSCAT, Protein kinase C Zeta isoform is critical for mitogenic signal transduction, Cell 74, 555-563 (1993).
-
(1993)
Cell
, vol.74
, pp. 555-563
-
-
Berra, E.1
Diaz Meco, M.T.2
Dominguez, I.3
Municio, M.M.4
Sanz, L.5
Lozano, J.6
Chapkin, R.S.7
Moscat, J.8
-
56
-
-
0028176502
-
Zeta PKC induces phosphorylation and inactivation of I K B-alpha in vitro
-
M. T. DIAZ MECO, I. DOMINGUEZ, L. SANZ, P. DENT, J. LOZANO, M. M. MUNICIO, E. BERRA, R. T. HAY, T. W. STURGILL and J. MOSCAT, zeta PKC induces phosphorylation and inactivation of I K B-alpha in vitro, EMBO J. 13, 2842-2848 (1994).
-
(1994)
EMBO J.
, vol.13
, pp. 2842-2848
-
-
Diaz Meco, M.T.1
Dominguez, I.2
Sanz, L.3
Dent, P.4
Lozano, J.5
Municio, M.M.6
Berra, E.7
Hay, R.T.8
Sturgill, T.W.9
Moscat, J.10
-
57
-
-
0026453081
-
Activation of the c-Raf protein kinase by protein kinase C phosphorylation
-
O. SÖZERI, K. VOLLMER, M. LIYANAGE, D. FRITH, G. KOUR, G. E. MARK and S. STABEL, Activation of the c-Raf protein kinase by protein kinase C phosphorylation, Oncogene 7, 2259-2262 (1992).
-
(1992)
Oncogene
, vol.7
, pp. 2259-2262
-
-
Sözeri, O.1
Vollmer, K.2
Liyanage, M.3
Frith, D.4
Kour, G.5
Mark, G.E.6
Stabel, S.7
-
58
-
-
0027326410
-
Protein kinase Ca activates RAF-1 by direct phosphorylation
-
W. KOLCH, G. HEIDECKER, G. KOCHS, R. HUMMEL, H. VAHIDI, H. MISCHAK, G. FINKENZELLER, D. MARME and U. R. RAPP, Protein kinase Ca activates RAF-1 by direct phosphorylation, Nature 364, 249-252 (1993).
-
(1993)
Nature
, vol.364
, pp. 249-252
-
-
Kolch, W.1
Heidecker, G.2
Kochs, G.3
Hummel, R.4
Vahidi, H.5
Mischak, H.6
Finkenzeller, G.7
Marme, D.8
Rapp, U.R.9
-
59
-
-
0026078253
-
Effects of hexadecylphosphocholine on protein kinase C and TPA-induced differentiation of HL60 cells
-
M. SHOJI, R. L. RANOR, E. A. M. FLEER, H. EIBL, W. R. VOGLER and J. F. KUO, Effects of hexadecylphosphocholine on protein kinase C and TPA-induced differentiation of HL60 cells, Lipids 26, 145-149 (1991).
-
(1991)
Lipids
, vol.26
, pp. 145-149
-
-
Shoji, M.1
Ranor, R.L.2
Fleer, E.A.M.3
Eibl, H.4
Vogler, W.R.5
Kuo, J.F.6
-
60
-
-
0025296440
-
Inhibition of protein kinase C, (sodium plus potassium)-activated adenosine triphosphatase, and sodium pump by synthetic phospholipid analogues
-
B. ZHENG, K. OISHI, M. SHOJI, H. EIBL, W. E. BERDEL, J. HAJDU, W. R. VOGLER and J. F. KUO, Inhibition of protein kinase C, (sodium plus potassium)-activated adenosine triphosphatase, and sodium pump by synthetic phospholipid analogues, Cancer Res. 50, 3025-3031 (1990).
-
(1990)
Cancer Res.
, vol.50
, pp. 3025-3031
-
-
Zheng, B.1
Oishi, K.2
Shoji, M.3
Eibl, H.4
Berdel, W.E.5
Hajdu, J.6
Vogler, W.R.7
Kuo, J.F.8
-
61
-
-
0026315413
-
The phospholipid analogue, hexadecylphosphocholine, inhibits protein kinase C in vitro and antagonizes phorbol ester-stimulated cell proliferation
-
C. C. GEILEN, R. HAASE, K. BUCHNER, T. WIEDER, F. HUCHO and W. REUTTER, The phospholipid analogue, hexadecylphosphocholine, inhibits protein kinase C in vitro and antagonizes phorbol ester-stimulated cell proliferation, Eur. J. Cancer 21, 1650-1653 (1991).
-
(1991)
Eur. J. Cancer
, vol.21
, pp. 1650-1653
-
-
Geilen, C.C.1
Haase, R.2
Buchner, K.3
Wieder, T.4
Hucho, F.5
Reutter, W.6
-
62
-
-
0026516946
-
Inhibition of PKC by ether-linked lipids is not correlated with their antineoplastic activity on WEHI-3B and R6X-B15 cells
-
H. SALARI, P. DRYDEN, R. DAVENPORT, S. HOWARD, K. JONES and R. BITTMAN, Inhibition of PKC by ether-linked lipids is not correlated with their antineoplastic activity on WEHI-3B and R6X-B15 cells, Biochim. Biophys. Acta 1134, 81-88 (1992).
-
(1992)
Biochim. Biophys. Acta
, vol.1134
, pp. 81-88
-
-
Salari, H.1
Dryden, P.2
Davenport, R.3
Howard, S.4
Jones, K.5
Bittman, R.6
-
64
-
-
0026445085
-
Phospholipases C and D in mitogenic signal transduction
-
S. J. COOK and M. J. WAKELAM, Phospholipases C and D in mitogenic signal transduction, Rev. Physiol. Biochem. Pharmacol. 119, 13-45 (1992).
-
(1992)
Rev. Physiol. Biochem. Pharmacol.
, vol.119
, pp. 13-45
-
-
Cook, S.J.1
Wakelam, M.J.2
-
65
-
-
0028296793
-
Phosphatidylcholine breakdown and signal transduction
-
S. H. EXTON, Phosphatidylcholine breakdown and signal transduction, Biochim. Biophys. Acta 1212, 26-42 (1994).
-
(1994)
Biochim. Biophys. Acta
, vol.1212
, pp. 26-42
-
-
Exton, S.H.1
-
66
-
-
0028269446
-
Phospholipase D activation in fibroblast membranes by the alpha and beta isoforms of protein kinase C
-
K. M. CONRICODE, J. L. SMITH, D. J. BURNS and J. H. EXTON, Phospholipase D activation in fibroblast membranes by the alpha and beta isoforms of protein kinase C, FEBS Lett. 342, 149-153 (1994).
-
(1994)
FEBS Lett.
, vol.342
, pp. 149-153
-
-
Conricode, K.M.1
Smith, J.L.2
Burns, D.J.3
Exton, J.H.4
-
68
-
-
0027397544
-
Inositol trisphosphate and calcium signalling
-
M. J. BERRIDGE, Inositol trisphosphate and calcium signalling, Nature 361, 315-325 (1993).
-
(1993)
Nature
, vol.361
, pp. 315-325
-
-
Berridge, M.J.1
-
69
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assay
-
T. MOSMAN, Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assay, J. Immunol. Meth. 65, 55-63 (1983).
-
(1983)
J. Immunol. Meth.
, vol.65
, pp. 55-63
-
-
Mosman, T.1
-
70
-
-
0024320738
-
+-antiporter by a protein kinase C-independent mechanism
-
+-antiporter by a protein kinase C-independent mechanism, J. Biol. Chem. 264, 11839-11842 (1989).
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 11839-11842
-
-
Maly, K.1
Überall, F.2
Loferer, H.3
Doppler, W.4
Oberhuber, H.5
Groner, B.6
Grunicke, H.H.7
-
71
-
-
0026035523
-
Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
-
T. K. H. VU, D. T. HUNG, V. I. WHEATON and S. R. COUGHLIN, Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation, Cell 64, 1057-1063 (1991).
-
(1991)
Cell
, vol.64
, pp. 1057-1063
-
-
Vu, T.K.H.1
Hung, D.T.2
Wheaton, V.I.3
Coughlin, S.R.4
-
73
-
-
0025293705
-
Phospholipase C-mediated hydrolysis of phosphatidylcholine is an important step in PDGF-stimulated DNA synthesis
-
P. LARRODERA, M. E. CORNET, M. T. DIAZ-MECO, M. LOPEZ-BARAHONA, I. DIAZ-LAVIADA, P. H. GUDDAL, T. JOHANSEN and J. MOSCAT, Phospholipase C-mediated hydrolysis of phosphatidylcholine is an important step in PDGF-stimulated DNA synthesis, Cell 61, 1113-1120 (1990).
-
(1990)
Cell
, vol.61
, pp. 1113-1120
-
-
Larrodera, P.1
Cornet, M.E.2
Diaz-Meco, M.T.3
Lopez-Barahona, M.4
Diaz-Laviada, I.5
Guddal, P.H.6
Johansen, T.7
Moscat, J.8
-
74
-
-
0027057976
-
Phospholipase C mimics platelet-derived growth factor as a competence factor in vascular smooth muscle cells
-
T. KONDO, H. INUI, F. KONISHI and T. INAGAMI, Phospholipase C mimics platelet-derived growth factor as a competence factor in vascular smooth muscle cells, J. Biol. Chem. 267, 23609-23616 (1992).
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 23609-23616
-
-
Kondo, T.1
Inui, H.2
Konishi, F.3
Inagami, T.4
-
75
-
-
0026658539
-
Purification and characterization of the zeta isoform of protein kinase C from bovine kidney
-
H. NAKANISHI and J. H. EXTON, Purification and characterization of the zeta isoform of protein kinase C from bovine kidney, J. Biol. Chem. 267, 16347-16354 (1992).
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 16347-16354
-
-
Nakanishi, H.1
Exton, J.H.2
-
76
-
-
0023927798
-
Kinetic analysis of 1,2-diacylglycerol mass levels in cultured fibroblasts. Comparison of stimulation by alpha-thrombin and epidermal growth factor
-
T. M. WRIGHT, L. A. RANGAN, H. S. SHIN and D. M. RABEN, Kinetic analysis of 1,2-diacylglycerol mass levels in cultured fibroblasts. Comparison of stimulation by alpha-thrombin and epidermal growth factor, J. Biol. Chem. 263, 9374-9380 (1988).
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 9374-9380
-
-
Wright, T.M.1
Rangan, L.A.2
Shin, H.S.3
Raben, D.M.4
-
77
-
-
0025133161
-
Kinetic and molecular species analyses of mitogen-induced increases in diglycerides: Evidence for stimulated hydrolysis of phosphoinositides and phosphatidylcholine
-
D. M. RABEN, M. S. PESSIN, L. A. RANGAN and T. M. WRIGHT, Kinetic and molecular species analyses of mitogen-induced increases in diglycerides: evidence for stimulated hydrolysis of phosphoinositides and phosphatidylcholine, J. Cell. Biochem. 44, 117-125 (1990).
-
(1990)
J. Cell. Biochem.
, vol.44
, pp. 117-125
-
-
Raben, D.M.1
Pessin, M.S.2
Rangan, L.A.3
Wright, T.M.4
-
78
-
-
0025317855
-
Molecular species analysis of mitogen-stimulated 1,2-diglycerides in fibroblasts. Comparison of alpha-thrombin, epidermal growth factor, and platelet-derived growth factor
-
M. S. PESSIN, J. J. BALDASSARE and D. M. RABENTI, Molecular species analysis of mitogen-stimulated 1,2-diglycerides in fibroblasts. Comparison of alpha-thrombin, epidermal growth factor, and platelet-derived growth factor, J. Biol. Chem. 265, 7959-7966 (1990).
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 7959-7966
-
-
Pessin, M.S.1
Baldassare, J.J.2
Rabenti, D.M.3
-
79
-
-
0028567280
-
Phosphatidic acid activation of protein kinase C-zeta overexpressed in COS cells: Comparison with other protein kinase C isotypes and other acidic lipids
-
C. LIMATOLA, D. SCHAAP, W. H. MOOLENAAR and W. J. VAN-BLITTERSWIJK, Phosphatidic acid activation of protein kinase C-zeta overexpressed in COS cells: comparison with other protein kinase C isotypes and other acidic lipids, Biochem. J. 304, 1001-1008 (1994).
-
(1994)
Biochem. J.
, vol.304
, pp. 1001-1008
-
-
Limatola, C.1
Schaap, D.2
Moolenaar, W.H.3
Van-Blitterswijk, W.J.4
-
80
-
-
0001245670
-
A second generation of alkylphospholipids with high antineoplastic activity
-
J. STEKAR, P. HILGARD, T. KLENNER, G. NOESSNER and W. SCHUMACHER, A second generation of alkylphospholipids with high antineoplastic activity, Proc. Am. Assoc. Cancer Res. 34, 335 (1993).
-
(1993)
Proc. Am. Assoc. Cancer Res.
, vol.34
, pp. 335
-
-
Stekar, J.1
Hilgard, P.2
Klenner, T.3
Noessner, G.4
Schumacher, W.5
-
81
-
-
0027320780
-
Antineoplastic activity and tolerability of a novel heterocyclic alkylphospholipid, D-20133
-
J. STEKAR, P. HILGARD, R. VOEGELI, H. R. MAURER, J. ENGEL, B. KUTSCHER, G. NÖSSNER and W. SCHUMACHER, Antineoplastic activity and tolerability of a novel heterocyclic alkylphospholipid, D-20133, Cancer Chemother. Pharmacol. 32, 437-444 (1993).
-
(1993)
Cancer Chemother. Pharmacol.
, vol.32
, pp. 437-444
-
-
Stekar, J.1
Hilgard, P.2
Voegeli, R.3
Maurer, H.R.4
Engel, J.5
Kutscher, B.6
Nössner, G.7
Schumacher, W.8
-
82
-
-
0343389916
-
A novel alkylphospholipid with arsenic substituting for nitrogen (D-21805)
-
J. STEKAR, P. HILGARD, T. KLENNER, B. KUTSCHER, G. NÖSSNER and R. VOEGELI, A novel alkylphospholipid with arsenic substituting for nitrogen (D-21805), J. Cancer Res. Clin. Oncol. 120 (Suppl): R164 (1994).
-
(1994)
J. Cancer Res. Clin. Oncol.
, vol.120
, Issue.SUPPL.
-
-
Stekar, J.1
Hilgard, P.2
Klenner, T.3
Kutscher, B.4
Nössner, G.5
Voegeli, R.6
-
83
-
-
0025978171
-
Platelet derived growth factor increases the in vivo activity of phospholipase C-gamma 1 and phospholipase C-gamma 2
-
L. SULTZMAN, C. ELLIS, L. L. LIN, T. PAWSON and J. KNOPF, Platelet derived growth factor increases the in vivo activity of phospholipase C-gamma 1 and phospholipase C-gamma 2, Mol. Cell. Biol. 11, 2018-2025 (1991).
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 2018-2025
-
-
Sultzman, L.1
Ellis, C.2
Lin, L.L.3
Pawson, T.4
Knopf, J.5
-
84
-
-
0027211693
-
Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal
-
M. VALIUS and A. KAZLAUSKAS, Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal, Cell 73, 321-334 (1993).
-
(1993)
Cell
, vol.73
, pp. 321-334
-
-
Valius, M.1
Kazlauskas, A.2
-
85
-
-
0025816451
-
Oncogenic forms of the neu/HER2 tyrosine kinase are permanently coupled to phospholipase C gamma
-
E. PELES, R. B. LEVY, E. OR, A. ULLRICH and Y. YARDEN, Oncogenic forms of the neu/HER2 tyrosine kinase are permanently coupled to phospholipase C gamma, EMBO J. 10, 2077-2086 (1991).
-
(1991)
EMBO J.
, vol.10
, pp. 2077-2086
-
-
Peles, E.1
Levy, R.B.2
Or, E.3
Ullrich, A.4
Yarden, Y.5
-
86
-
-
0002741730
-
Specific expression of phospholipase C-γ in human glial tumors
-
N. HAAS, H. McDANEL and A. GODWIN, Specific expression of phospholipase C-γ in human glial tumors, Proc. Am. Assoc. Cancer Res. 32, 17 (1991).
-
(1991)
Proc. Am. Assoc. Cancer Res.
, vol.32
, pp. 17
-
-
Haas, N.1
McDanel, H.2
Godwin, A.3
-
87
-
-
0005356220
-
Increased phospholipase C (PLC)-γ, activity in human non-small cell lung (NSCLC) and renal cell (RCC) carcinomas correlated with elevated EGF receptor levels
-
J. B. ROBERTSON, S. D. HURD and M. O. KOCH, Increased phospholipase C (PLC)-γ, activity in human non-small cell lung (NSCLC) and renal cell (RCC) carcinomas correlated with elevated EGF receptor levels, Proc. Am. Assoc. Cancer Res. 33, 89 (1992).
-
(1992)
Proc. Am. Assoc. Cancer Res.
, vol.33
, pp. 89
-
-
Robertson, J.B.1
Hurd, S.D.2
Koch, M.O.3
-
88
-
-
0024673503
-
S-phase induction and transformation of quiescent NIH 3T3 cells by microinjection of phospholipase C
-
M. R. SMITH, S. H. RYU, P. G. SUH, S. G. RHEE and H. F. KUNG, S-phase induction and transformation of quiescent NIH 3T3 cells by microinjection of phospholipase C, Proc. Natl. Acad. Sci. U.S.A 86, 3659-3663 (1989).
-
(1989)
Proc. Natl. Acad. Sci. U.S.A
, vol.86
, pp. 3659-3663
-
-
Smith, M.R.1
Ryu, S.H.2
Suh, P.G.3
Rhee, S.G.4
Kung, H.F.5
-
89
-
-
0025855010
-
Muscarinic acetylcholine receptor subtypes as agonist-dependent oncogenes
-
J. S. GUTKIND, E. A. NOVOTNY, M. R. BRANN and K. C. ROBBINS, Muscarinic acetylcholine receptor subtypes as agonist-dependent oncogenes, Proc. Natl. Acad. Sci. U.S.A 88, 4703-4707 (1991).
-
(1991)
Proc. Natl. Acad. Sci. U.S.A
, vol.88
, pp. 4703-4707
-
-
Gutkind, J.S.1
Novotny, E.A.2
Brann, M.R.3
Robbins, K.C.4
-
90
-
-
0027503305
-
Muscarinic receptor-mediated tyrosine phosphorylation of phospholipase C-gamma. An alternative mechanism for cholinergic-induced phosphoinositide breakdown
-
F. GUSOVSKY, J. E. LUEDERS, E. C. KOHN and C. C. FELDER, Muscarinic receptor-mediated tyrosine phosphorylation of phospholipase C-gamma. An alternative mechanism for cholinergic-induced phosphoinositide breakdown, J. Biol. Chem. 268, 7768-7772 (1993).
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 7768-7772
-
-
Gusovsky, F.1
Lueders, J.E.2
Kohn, E.C.3
Felder, C.C.4
-
91
-
-
0026731562
-
2+ flux but not mitogenesis
-
2+ flux but not mitogenesis, Nature 358, 678-681 (1992).
-
(1992)
Nature
, vol.358
, pp. 678-681
-
-
Peters, K.G.1
Marie, J.2
Wilson, E.3
Ives, H.E.4
Escobedo, J.5
Del-Rosario, M.6
Mirda, D.7
Williams, L.T.8
-
93
-
-
0026654469
-
Regulation of inositol phospholipid-specific phospholipase C isozymes
-
S. G. RHEE and K. D. CHOI, Regulation of inositol phospholipid-specific phospholipase C isozymes, J. Biol. Chem. 267, 12393-12396 (1992).
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 12393-12396
-
-
Rhee, S.G.1
Choi, K.D.2
-
94
-
-
0028296793
-
Phosphatidylcholine breakdown and signal transduction
-
J. H. EXTON, Phosphatidylcholine breakdown and signal transduction, Biochim. Biophys. Acta 1212, 26-42 (1994).
-
(1994)
Biochim. Biophys. Acta
, vol.1212
, pp. 26-42
-
-
Exton, J.H.1
-
95
-
-
0026770104
-
Crosstalk among multiple signal-activated phospholipases
-
M. LISCOVITCH, Crosstalk among multiple signal-activated phospholipases, Trends Biochem. Sci. 17, 393-399 (1992).
-
(1992)
Trends Biochem. Sci.
, vol.17
, pp. 393-399
-
-
Liscovitch, M.1
-
96
-
-
0023735168
-
Antiproliferative effect of verapamil alone on brain tumor cells in vitro
-
W. F. SCHMIDT, K. R. HUBER, R. S. ETTINGER and R. W. NEUBERG, Antiproliferative effect of verapamil alone on brain tumor cells in vitro, Cancer Res. 48, 3617-3621 (1988).
-
(1988)
Cancer Res.
, vol.48
, pp. 3617-3621
-
-
Schmidt, W.F.1
Huber, K.R.2
Ettinger, R.S.3
Neuberg, R.W.4
-
97
-
-
0026624967
-
Inhibition of cancer cell growth by calcium channel antagonists in the athymic mouse
-
J. M. TAYLOR and R. U. SIMPSON, Inhibition of cancer cell growth by calcium channel antagonists in the athymic mouse, Cancer Res. 52, 2413-2418 (1992).
-
(1992)
Cancer Res.
, vol.52
, pp. 2413-2418
-
-
Taylor, J.M.1
Simpson, R.U.2
-
98
-
-
0023819705
-
2+-mobilizing system to serum growth factors by Ha-ras and v-mos
-
2+-mobilizing system to serum growth factors by Ha-ras and v-mos, Molecular and Cellular Biology 8, 4212-4216 (1988).
-
(1988)
Molecular and Cellular Biology
, vol.8
, pp. 4212-4216
-
-
Maly, K.1
Doppler, W.2
Oberhuber, H.3
Meusburger, H.4
Hofmann, J.5
Jaggi, R.6
Grunicke, H.H.7
-
99
-
-
0021750054
-
Inositol trisphosphate, a novel second messenger in cellular signal transduction
-
M. J. BERRIDGE and R. F. IRVINE, Inositol trisphosphate, a novel second messenger in cellular signal transduction, Nature 312, 315-321 (1984).
-
(1984)
Nature
, vol.312
, pp. 315-321
-
-
Berridge, M.J.1
Irvine, R.F.2
|