Lysosomal enzyme activities in gallbladder mucosa of gallstone-free subjects and patients with gallstones

Journal of Hepatology

Volumn 25, Issue 6, 1996, Pages 895-899

  Sahlin, Staffan ^a   Glauman, Hans ^b   Danielsson, Åke ^c   Einarsson, Kurt ^b  

^a DANDERYD HOSPITAL   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c NONE

Author keywords

Cholecystectomy; Cholesterol gallstone; Cholesterol saturation; Liver parenchyma; Mucin

Indexed keywords

CHOLESTEROL; LYSOSOME ENZYME;

ADULT; ARTICLE; CHOLESTEROL STONE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GALLBLADDER DISEASE; GALLBLADDER MUCOSA; GALLSTONE; HUMAN; LIVER; MALE; PRIORITY JOURNAL;

EID: 0030445275     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(96)80294-7     Document Type: Article

References (32)

1. 1. Hofmann AF. Pathogenesis of cholesterol gallstones. J Clin Gastroenterol 1988; 10 (suppl 2): S1-11.
2. 2. Lamont JT, Carey MC. Cholesterol gallstone formation. 2. Pathobiology and pathomechanics. Progr Liver Dis 1992; 10: 165-91.
3. 3. Holan KR, Holzbach RT, Hermann RE, Cooperman AM, Claffey WJ. Nucleating time: a key factor in pathogenesis of cholesterol gallstone disease. Gastroenterology 1979; 77: 611-7.
4. 4. Sahlin S, Ahlberg J, Angelin B, Reihnér E, Einarsson K. Nucleation time of gallbladder bile in gallstone patients: influence of bile acid treatment. Gut 1991; 32: 1554-7.
5. 5. Holzbach RT. Recent progress in understanding cholesterol crystal nucleation as a precursor to human gallstone formation. Hepatology 1986; 6: 1403-6.
6. 6. Doty JE, Pitt HA, Kuchenbecker SL, Porter-Fink V, DenBesten LW. Role of gallbladder mucus in the pathogenesis of cholesterol gallstones. Am J Surg 1983; 145: 54-61.
7. 7. Zac RA, Frenkiel PG, Marks JW, Bonorris GG, Allen A, Schoenfield LJ. Cyclic nucleotides and glycoproteins during formation of cholesterol gallstones in prairie dogs. Gastroenterology 1984; 87: 263-9.
8. 8. LaMont JT, Smith BF, Moore JRL. Role of gallbladder mucin in pathophysiology of gallstones. Hepatology 1984; 4: S51-6.
9. 9. LaMorte WW, Booker ML, Scott TE, Williams LF Jr. Increases in gallbladder prostaglandin synthesis before the formation of cholesterol gallstones. Surgery 1985; 98: 445-51.
10. 10. Li YF, Moody FG, Weisbrodt NW, Zalewsky CA, Coelho JCU, Senninger ND. Gallbladder contractility and mucus secretion after cholesterol feeding in the prairie dog. Surgery 1986; 100: 900-4.
11. 11. Bouchier IAD, Cooperband SR, El Kodsi BM. Mucous substances and viscosity of normal and pathological human bile. Gastroenterology 1965; 49: 343-53.
12. 12. Lee SP, Lim TH, Scott AJ. Carbohydrate moieties of glycoproteins in human hepatic and gallbladder bile, gallbladder mucosa and gall stones. Clin Sci 1979; 56: 533-8.
13. 13. Gallinger S, Harvey PRC, Petrunka CN, Ilson RG, Strasberg SM. Biliary proteins and the nucleation defect in cholesterol cholelithiasis. Gastroenterology 1987; 92: 867-75.
14. 14. Sahlin S, Danielsson Angelin B, Reihnér E, Henriksson R, Einarsson K. Mucin in gallbladder bile of gall stone patients: influence of treatment with chenodeoxycholic acid and ursodeoxycholic acid. Gut 1988; 29: 1506-10.
15. 15. Mingrone G, Greco AV, Finotti E, Passi S. Free fatty acids: a stimulus for mucin hypersecretion in cholesterol gallstone biles. Biochim Biophys Acta 1988; 958: 52-9.
16. 16. Swobodnik W, Wenk H, Janowitz P, Hagert N, Kratzer W, Berghold J, Zhang Y, Bittner R, Schusdiziarra V, Ott R, Kuhn K, Classen M. Total biliary protein, mucus glycoproteins, cyclic-AMP, and apolipoproteins in the gallbladder bile of patients with cholesterol gallstones and stone-free controls. Scand J Gastroenterol 1991; 26: 771-8.
17. 17. Sahlin S, Ahlberg J, Einarsson K, Henriksson R, Danielsson Å. Quantitative ultrastructural studies of gallbladder epithelium in gallstone-free subjects and patients with gallstones. Gut 1990; 31: 100-5.
18. 18. Trotman BW, Ostrow JD, Soloway RD. Pigment v cholesterol cholelithiasis: comparison of stone and bile composition. Am J Dig Dis 1974; 19: 585-90.
19. 19. Whiting MJ, Down RH, Watts JMcK. Biliary crystals and granules, the cholesterol saturation index, and the prediction of gallstone type. Surg Gastroenterol 1982; 1: 17-21.
20. 20. Tera H, Stratification of human gallbladder bile in vivo. Acta Chir Scand 1960; Suppl 256: 4-65.
21. 21. Roda A, Festi D, Sama C, Mazzeli G, Aldiní R, Roda E, et al. Enzymatic determination of cholesterol in bile. Clin Chim Acta 1975; 64: 337-41.
22. 22. Rouser G, Sidney F, Akira Y. Two dimensional thin-layer chromatography separation of polar lipids and determination of phospholipids by phosphorus analysis of spots. Lipids 1975; 5: 494-6.
23. 23. Fausa O, Skålhegg BA. Quantitative determination of bile acids and their conjugates using thin-layer chromatography and purified 3-α-hydroxysteroid dehydrogenase. Scand J Gastroent 1974; 9: 249-54.
24. 24. Carey MC. Critical tables for calculating the cholesterol saturation of native bile. J Lipid Res 1978; 19: 945-55.
25. 25. Sahlin S. Total protein content in human gallbladder bile: relation to cholesterol gallstone disease and effects of bile acid and aspirin treatment. Eur J Surg 1996; 162: 463-9.
26. 26. Barrett AJ, Kirschke H. Cathepsin B, cathepsin H and cathepsin L. Meth Enzymol 1981; 80: 535-81.
27. 27. Bowers WE, Finkelstaedt JT, de Duve C. Lysosomes in lymphoid tissue. 1. The measurement of hydrolytic activities in whole homogenates. J Cell Biol 1967; 32: 325-41.
28. 28. Kouroumalis E, Hopwood D, Ross PE, Milne G, Bouchier IAD. Gallbladder epithelial acid hydolases in human cholecystis. J Pathol 1983; 139: 179-91.
29. 29. Kouroumalis E, Hopwood D, Ross PE, Bouchier IAD. Human gallbladder epithelium; non-specific esterases in cholecystitis. J Pathol 1984; 142: 151-9.
30. 30. Strasberg SM, Toth JL, Gallinger S, Harvey PRC. High protein and total lipid concentration are associated with reduced metastability of bile in an early stage of cholesterol gallstone formation. Gastroenterology 1990; 98: 739-46.
31. 31. Yu L, Guan-Zang L. Qualitative and quantitative comparison of gallbladder protein from patients with and without cholesterol gallstones. Dig Dis Sci 1990; 35: 47-9.
32. 32. Jungst D, Lang T, von Ritter C, Paumgartner G. Role of high total protein in gallbladder bile in the formation of cholesterol gallstones. Gastroenterology 1991; 100: 1724-9.