Acquisition of the ts Phenotype by a Chemically Mutagenized Cold-passaged Human Respiratory Syncytial Virus Vaccine Candidate Results from the Acquisition of a Single Mutation in the Polymerase (L) Gene

Virus Genes

Volumn 13, Issue 3, 1996, Pages 269-273

  Crowe Jr , James E ^a   Firestone, Cai Yen ^a   Whitehead, Stephen S ^a   Collins, Peter L ^a   Murphy, Brian R ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Respiratory syncytial virus; Temperature sensitive mutant; Viral polymerase

Indexed keywords

RESPIRATORY SYNCYTIAL VIRUS VACCINE; RNA POLYMERASE; VIRUS ENZYME;

ANIMAL CELL; ARTICLE; CHEMICAL MUTAGENESIS; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PHENOTYPE; PRIORITY JOURNAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; STRUCTURAL GENE; TEMPERATURE SENSITIVE MUTANT; VIRUS ATTENUATION; VIRUS MUTANT;

ANIMALS; BASE SEQUENCE; CERCOPITHECUS AETHIOPS; COLD; DNA, VIRAL; DNA-DIRECTED RNA POLYMERASES; GENES, VIRAL; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PHENOTYPE; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; VERO CELLS; VIRAL PROTEINS; VIRAL VACCINES;

EID: 0030445267     PISSN: 09208569     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00366988     Document Type: Article

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