메뉴 건너뛰기




Volumn 15, Issue 6, 1996, Pages 406-429

A Risk-Benefit Assessment of Anthracycline Antibiotics in Antineoplastic Therapy

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE ANTIBIOTIC AGENT; CARUBICIN; DAUNORUBICIN; DOXORUBICIN; EPIRUBICIN; ESORUBICIN; IDARUBICIN; LIPOSOME; RAZOXANE; VALRUBICIN; ZORUBICIN;

EID: 0030444894     PISSN: 01145916     EISSN: None     Source Type: Journal    
DOI: 10.2165/00002018-199615060-00005     Document Type: Article
Times cited : (35)

References (208)
  • 1
    • 0019501881 scopus 로고
    • The anthracycline antineoplastic drugs
    • Young RC, Ozols RF, Myers CE. The anthracycline antineoplastic drugs. N Engl J Med 1981; 305 (3): 139-53
    • (1981) N Engl J Med , vol.305 , Issue.3 , pp. 139-153
    • Young, R.C.1    Ozols, R.F.2    Myers, C.E.3
  • 2
    • 0014473575 scopus 로고
    • Adriamycin NSC-123,127: A new antibiotic with untitumor activity
    • Di Marco A, Gaetani F, Scarpinoto B. Adriamycin NSC-123,127: a new antibiotic with untitumor activity. Cancer Chemother Rep 1969; 53: 33-7
    • (1969) Cancer Chemother Rep , vol.53 , pp. 33-37
    • Di Marco, A.1    Gaetani, F.2    Scarpinoto, B.3
  • 3
    • 0007958821 scopus 로고
    • Un novel antibiotique a proprietes cytostatiques: La rudidomycin
    • Dubost M,. Gaetani M, Dorigotto L, et al. Un novel antibiotique a proprietes cytostatiques: la rudidomycin. CR Hebd Scances Acad Sci 1965; 257: 1813-5
    • (1965) CR Hebd Scances Acad Sci , vol.257 , pp. 1813-1815
    • Dubost, M.1    Gaetani, M.2    Dorigotto, L.3
  • 4
    • 0014603427 scopus 로고
    • Adriamycin: 14 hydroxydaunomycin, a new antitumor antibiotic from S. peucetius var. caesius
    • Arcamone F, Cassinelli G, Fantini G, et al. Adriamycin: 14 hydroxydaunomycin, a new antitumor antibiotic from S. peucetius var. caesius. Biotechnol Bioeng 1969; 11: 1101-10
    • (1969) Biotechnol Bioeng , vol.11 , pp. 1101-1110
    • Arcamone, F.1    Cassinelli, G.2    Fantini, G.3
  • 5
    • 0017276466 scopus 로고
    • The cardiotoxicity of adriamycin and daunomycin in children
    • Giladaga AC, Manuel C, Tan CT, et al. The cardiotoxicity of adriamycin and daunomycin in children. Cancer 1976; 37: 1070-8
    • (1976) Cancer , vol.37 , pp. 1070-1078
    • Giladaga, A.C.1    Manuel, C.2    Tan, C.T.3
  • 6
    • 0015849162 scopus 로고
    • A clinico-pathological analysis of adriamycin cardiotoxicity
    • Lefrak EA, Pitha J, Rosenheem S, et al. A clinico-pathological analysis of adriamycin cardiotoxicity. Cancer 1973; 32: 302-14
    • (1973) Cancer , vol.32 , pp. 302-314
    • Lefrak, E.A.1    Pitha, J.2    Rosenheem, S.3
  • 7
  • 8
    • 0018192615 scopus 로고
    • Comparative mammalian metabolism of adriamycin and daunomycin
    • Loveless H, Arena E, Felstead RL, et al. Comparative mammalian metabolism of adriamycin and daunomycin. Cancer Res 1978; 38: 593-8
    • (1978) Cancer Res , vol.38 , pp. 593-598
    • Loveless, H.1    Arena, E.2    Felstead, R.L.3
  • 9
    • 0021247277 scopus 로고
    • Metabolism of 4′ modified analogs of doxorubicin's unique glucuronidation pathway to 4 epidoxorubicin
    • Weenan H, Van Maanen JMS, De Planque MM, et al. Metabolism of 4′ modified analogs of doxorubicin's unique glucuronidation pathway to 4 epidoxorubicin. Eur J Cancer Clin Oncol 1984; 20: 919-26
    • (1984) Eur J Cancer Clin Oncol , vol.20 , pp. 919-926
    • Weenan, H.1    Van Maanen, J.M.S.2    De Planque, M.M.3
  • 10
    • 0028558733 scopus 로고
    • Dose optimization of anthracyclines
    • De Valeriola D. Dose optimization of anthracyclines. Anticancer Res 1994, 14: 2307-14
    • (1994) Anticancer Res , vol.14 , pp. 2307-2314
    • De Valeriola, D.1
  • 11
    • 0027787743 scopus 로고
    • Pharmacokinetics and metabolism of anthracyclines
    • Robert J, Gianni L. Pharmacokinetics and metabolism of anthracyclines. Cancer Surv 1993; 17: 219-52
    • (1993) Cancer Surv , vol.17 , pp. 219-252
    • Robert, J.1    Gianni, L.2
  • 12
    • 0025020585 scopus 로고
    • Comparative pharmacokinetics of escalating doses of doxorubicin in patients with metastatic breast cancer
    • Bronchud MH, Margison JM, Howell A, et al. Comparative pharmacokinetics of escalating doses of doxorubicin in patients with metastatic breast cancer. Cancer Chemother Pharmacol 1990; 25; 435-9
    • (1990) Cancer Chemother Pharmacol , vol.25 , pp. 435-439
    • Bronchud, M.H.1    Margison, J.M.2    Howell, A.3
  • 13
    • 0021840229 scopus 로고
    • Comparative pharmacokinetics and metabolism of doxorubicin and epirubicin in patients with metastatic breast cancer
    • Robert J, Vrignaud P, Nguyen-Ngoc T, et al. Comparative pharmacokinetics and metabolism of doxorubicin and epirubicin in patients with metastatic breast cancer. Cancer Treat Rep 1985; 69: 633-40
    • (1985) Cancer Treat Rep , vol.69 , pp. 633-640
    • Robert, J.1    Vrignaud, P.2    Nguyen-Ngoc, T.3
  • 14
    • 0026714331 scopus 로고
    • The anthracyclines: Will we ever find a better doxorubicin?
    • Weiss RB. The anthracyclines: will we ever find a better doxorubicin? Semin Oncol 1992; 19 (6): 670-86
    • (1992) Semin Oncol , vol.19 , Issue.6 , pp. 670-686
    • Weiss, R.B.1
  • 15
  • 16
    • 84947886894 scopus 로고
    • Liquid chromatographic analysis of adriamycin and daunorubicin and their hydroxyl metabolites in biological fluids
    • Israel M, Pegge WJ, Wilkinson PM. Liquid chromatographic analysis of adriamycin and daunorubicin and their hydroxyl metabolites in biological fluids. Liquid Chromatog 1978; 1: 795-809
    • (1978) Liquid Chromatog , vol.1 , pp. 795-809
    • Israel, M.1    Pegge, W.J.2    Wilkinson, P.M.3
  • 17
    • 0016800963 scopus 로고
    • Preliminary pharmacokinetics model for adriamycin
    • Harris PA, Gross JF. Preliminary pharmacokinetics model for adriamycin. Cancer Chemother Rep 1975; 59: 819-27
    • (1975) Cancer Chemother Rep , vol.59 , pp. 819-827
    • Harris, P.A.1    Gross, J.F.2
  • 18
    • 0015494420 scopus 로고
    • Stereochemistry of intercalation: Interactions of daunomycin with DNA
    • Pigram WJ, Fuller W, Hamilton LD. Stereochemistry of intercalation: interactions of daunomycin with DNA. Nature 1972; 235: 17-9
    • (1972) Nature , vol.235 , pp. 17-19
    • Pigram, W.J.1    Fuller, W.2    Hamilton, L.D.3
  • 19
    • 0024468481 scopus 로고
    • DNA topoisomerase II mediated interaction of doxorubicin and daunorubicin congeners with DNA
    • Badley A, Liu LF, Israel M, et al. DNA topoisomerase II mediated interaction of doxorubicin and daunorubicin congeners with DNA. Cancer Res 1989; 49: 5969-78
    • (1989) Cancer Res , vol.49 , pp. 5969-5978
    • Badley, A.1    Liu, L.F.2    Israel, M.3
  • 20
    • 0026047307 scopus 로고
    • Contribution of glutathione and glutathione dependant enzymes in the reversal of adriamycin resistance in colon carcinoma cell lines
    • Lai GM, Moscow JA, Alvarez MG, et al. Contribution of glutathione and glutathione dependant enzymes in the reversal of adriamycin resistance in colon carcinoma cell lines. Int J Cancer 1991; 49: 688-95
    • (1991) Int J Cancer , vol.49 , pp. 688-695
    • Lai, G.M.1    Moscow, J.A.2    Alvarez, M.G.3
  • 21
    • 0023130297 scopus 로고
    • Adnamycin-stimulated hydroxyl formation in human breast tumour cells
    • Sinha BK, Katki AG, Batist G, et al. Adnamycin-stimulated hydroxyl formation in human breast tumour cells. Biochem Pharmacol 1987; 36: 793-6
    • (1987) Biochem Pharmacol , vol.36 , pp. 793-796
    • Sinha, B.K.1    Katki, A.G.2    Batist, G.3
  • 22
    • 0018915753 scopus 로고
    • Enzymatic defences of the mouse heart against reactive oxygen metabolites
    • Doroshow JH, Locker GY, Myers CE. Enzymatic defences of the mouse heart against reactive oxygen metabolites. J Clin Invest 1980; 65: 128-35
    • (1980) J Clin Invest , vol.65 , pp. 128-135
    • Doroshow, J.H.1    Locker, G.Y.2    Myers, C.E.3
  • 23
    • 0027343763 scopus 로고
    • Strategies for prevention of anthracycline cardiotoxicity
    • Basser RL, Green MD. Strategies for prevention of anthracycline cardiotoxicity. Cancer Treat Symp 1993; 19: 57-77
    • (1993) Cancer Treat Symp , vol.19 , pp. 57-77
    • Basser, R.L.1    Green, M.D.2
  • 24
    • 0019992950 scopus 로고
    • Oxidative destruction of erythrocyte ghost membranes catalyzed by the doxorubicin-iron complex
    • Myers CE, Gianna L, Simone CB, et al. Oxidative destruction of erythrocyte ghost membranes catalyzed by the doxorubicin-iron complex. Biochemistry 1982; 21: 1707-13
    • (1982) Biochemistry , vol.21 , pp. 1707-1713
    • Myers, C.E.1    Gianna, L.2    Simone, C.B.3
  • 25
    • 0022979812 scopus 로고
    • The role of iron in adriamycin biochemistry
    • Myers CE, Gianna L, Zwerer JL, et al. The role of iron in adriamycin biochemistry. Fed Proc 1986; 45: 2792-7
    • (1986) Fed Proc , vol.45 , pp. 2792-2797
    • Myers, C.E.1    Gianna, L.2    Zwerer, J.L.3
  • 26
    • 0021284858 scopus 로고
    • ++ complex to membrane phospholipids
    • ++ complex to membrane phospholipids. Eur J Biochem 1984; 142: 571-5
    • (1984) Eur J Biochem , vol.142 , pp. 571-575
    • Demant, E.J.1
  • 27
    • 0021349406 scopus 로고
    • Acute doxorubicin toxicity: Relationship to pre-treatment liver function response and pharmacokinetics in patients with acute non-lymphocytic leukaemia
    • Brenner DE, Wiernik PH, Wesley M, et al. Acute doxorubicin toxicity: relationship to pre-treatment liver function response and pharmacokinetics in patients with acute non-lymphocytic leukaemia. Cancer 1984; 53; 1042-8
    • (1984) Cancer , vol.53 , pp. 1042-1048
    • Brenner, D.E.1    Wiernik, P.H.2    Wesley, M.3
  • 28
    • 0015987706 scopus 로고
    • Adriamycin chemotherapy-efficacy, safety and pharmacological basis of an intermittent single high dose schedule
    • Benjamin RS, Wiernik PH, Bachur NR. Adriamycin chemotherapy-efficacy, safety and pharmacological basis of an intermittent single high dose schedule. Cancer 1974; 33: 19-25
    • (1974) Cancer , vol.33 , pp. 19-25
    • Benjamin, R.S.1    Wiernik, P.H.2    Bachur, N.R.3
  • 29
    • 0026577549 scopus 로고
    • Clinical efficacy and toxicity of standard dose adriamycin in hyperbilirubinaemic patients with hepatocellular carcinoma; relation to liver tests and pharmacokinetic parameters
    • Johnson PJ, Dobbs N, Kalayci C, et al. Clinical efficacy and toxicity of standard dose adriamycin in hyperbilirubinaemic patients with hepatocellular carcinoma; relation to liver tests and pharmacokinetic parameters. Br J Cancer 1992; 65: 751-5
    • (1992) Br J Cancer , vol.65 , pp. 751-755
    • Johnson, P.J.1    Dobbs, N.2    Kalayci, C.3
  • 30
    • 1842660531 scopus 로고
    • Hepatotoxicity of chemotherapeutic agents
    • Perry MC, editor. Orlando: Grune and Stratton
    • Perry MC, Yarbro JN. Hepatotoxicity of chemotherapeutic agents. In: Perry MC, editor. Toxicity of chemotherapy. 1st ed. Orlando: Grune and Stratton, 1984: 297-315
    • (1984) Toxicity of Chemotherapy. 1st Ed. , pp. 297-315
    • Perry, M.C.1    Yarbro, J.N.2
  • 31
    • 0017098634 scopus 로고
    • A randomised comparison of doxorubicin dose with a combination of daunorubicin (NSC 82151) alone, cytosine arabinoside (NSC 63878), thioguanine (NSC 752) and pyrimethamine (NSC 3061) for the treatment of acute non-lymphocytic leukaemia
    • Wiernik PH, Schimpff SC, Schiffer CA, et al. A randomised comparison of doxorubicin dose with a combination of daunorubicin (NSC 82151) alone, cytosine arabinoside (NSC 63878), thioguanine (NSC 752) and pyrimethamine (NSC 3061) for the treatment of acute non-lymphocytic leukaemia. Cancer Treat Rep 1976; 60: 41-53
    • (1976) Cancer Treat Rep , vol.60 , pp. 41-53
    • Wiernik, P.H.1    Schimpff, S.C.2    Schiffer, C.A.3
  • 32
    • 0018373277 scopus 로고
    • A comparative trial of daunomycin, ara-c, thioguanine and a combination of the three agents for the treatment of acute myelocytic leukaemia
    • Wiernik PS, Glidewell WJ, Hoagland HL, et al. A comparative trial of daunomycin, ara-c, thioguanine and a combination of the three agents for the treatment of acute myelocytic leukaemia. Med Pediatr Oncol 1979; 6: 261-77
    • (1979) Med Pediatr Oncol , vol.6 , pp. 261-277
    • Wiernik, P.S.1    Glidewell, W.J.2    Hoagland, H.L.3
  • 33
    • 0015721940 scopus 로고
    • Cytosine arabinoside (NSC 63878) and daunorubicin (NSC 83142) in acute N.L.L
    • Yates JW, Wallace Jr MT, Ellison RR, et al. Cytosine arabinoside (NSC 63878) and daunorubicin (NSC 83142) in acute N.L.L. Cancer Chemother Rep 1973; 57: 485-7
    • (1973) Cancer Chemother Rep , vol.57 , pp. 485-487
    • Yates, J.W.1    Wallace Jr., M.T.2    Ellison, R.R.3
  • 34
    • 0019979989 scopus 로고
    • Cytosine-arabinoside with daunorubicin or adriamycin for therapy of AML: A CALGB study
    • Yates JW, Glidewell OJ, Wiernik PH. Cytosine-arabinoside with daunorubicin or adriamycin for therapy of AML: a CALGB study. Blood 1982; 60: 454-62
    • (1982) Blood , vol.60 , pp. 454-462
    • Yates, J.W.1    Glidewell, O.J.2    Wiernik, P.H.3
  • 35
  • 36
    • 0025878611 scopus 로고
    • Does more intensive treatment cure more patients with AML?
    • Reiffers J, Maraninchi F, Rigal-Huguet M, et al. Does more intensive treatment cure more patients with AML? Semin Hematol 1991; 29 (3) Suppl. 4: 90-92
    • (1991) Semin Hematol , vol.29 , Issue.3-4 SUPPL. , pp. 90-92
    • Reiffers, J.1    Maraninchi, F.2    Rigal-Huguet, M.3
  • 37
    • 1842811552 scopus 로고    scopus 로고
    • Idarubicin in the treatment of relapsed or refractory AML
    • 198
    • Harousseau JL, Hurteloup P, Reiffers J, et al. Idarubicin in the treatment of relapsed or refractory AML [letter]. Cancer Treat Rep 198; 7: 991-2
    • Cancer Treat Rep , vol.7 , pp. 991-992
    • Harousseau, J.L.1    Hurteloup, P.2    Reiffers, J.3
  • 38
    • 0023750607 scopus 로고
    • Phase I trial of orally administered 4-demethoxy-daunorubicin (idarubicin), with pharmacokinetic and in-vitro drug sensitivity testing in children with refractory leukaemia
    • Pui CH, Seibold SN, de Graaf SS, et al. Phase I trial of orally administered 4-demethoxy-daunorubicin (idarubicin), with pharmacokinetic and in-vitro drug sensitivity testing in children with refractory leukaemia. Cancer Res 1988; 48: 5348-52
    • (1988) Cancer Res , vol.48 , pp. 5348-5352
    • Pui, C.H.1    Seibold, S.N.2    De Graaf, S.S.3
  • 39
    • 0025907179 scopus 로고
    • Results of a randomised trial comparing idarubicin and cytosine arabinoside with daunorubicin and cytosine arabinoside in adult patients with newly diagnosed acute myelogenous leukaemia
    • Berman E, Heller G, Santorsa JA, et al. Results of a randomised trial comparing idarubicin and cytosine arabinoside with daunorubicin and cytosine arabinoside in adult patients with newly diagnosed acute myelogenous leukaemia. Blood 1991; 77: 1666-74
    • (1991) Blood , vol.77 , pp. 1666-1674
    • Berman, E.1    Heller, G.2    Santorsa, J.A.3
  • 40
    • 0026650021 scopus 로고
    • A phase III trial comparing idarubicin and daunorubicin in combination with cytarabine in acute myelogenous leukaemia: A South Eastern Cancer Study Group Study
    • Vogler WR, Velez-Garcia E, Weiner RS, et al. A phase III trial comparing idarubicin and daunorubicin in combination with cytarabine in acute myelogenous leukaemia: a South Eastern Cancer Study Group Study. J Clin Oncol 1992; 10: 1103-11
    • (1992) J Clin Oncol , vol.10 , pp. 1103-1111
    • Vogler, W.R.1    Velez-Garcia, E.2    Weiner, R.S.3
  • 41
    • 0026586008 scopus 로고
    • Cytarabine plus idarubicin or daunorubicin as induction and consolidation therapy for previously untreated adult patients with acute myeloid leukaemia
    • Wiernik PH, Banks PLC, Case DC, et al. Cytarabine plus idarubicin or daunorubicin as induction and consolidation therapy for previously untreated adult patients with acute myeloid leukaemia. Blood 1992; 79: 313-9
    • (1992) Blood , vol.79 , pp. 313-319
    • Wiernik, P.H.1    Banks, P.L.C.2    Case, D.C.3
  • 42
    • 0018139450 scopus 로고
    • Intermittent combination chemotherapy with adriamycin for childhood acute lymphoblastic leukaemia: Clinical results
    • Sallon SE, Camitta BM, Cassady JR, et al. Intermittent combination chemotherapy with adriamycin for childhood acute lymphoblastic leukaemia: clinical results. Blood 1975; 51: 425-33
    • (1975) Blood , vol.51 , pp. 425-433
    • Sallon, S.E.1    Camitta, B.M.2    Cassady, J.R.3
  • 43
    • 0022461554 scopus 로고
    • The impact of induction anthracycline in long term failure free survival in childhood acute lymphoblastic leukaemia
    • Hitchcock-Bryan S, Gelber R, Cassady JR, et al. The impact of induction anthracycline in long term failure free survival in childhood acute lymphoblastic leukaemia. Med Pediatr Oncol 1986; 14 (4): 211-5
    • (1986) Med Pediatr Oncol , vol.14 , Issue.4 , pp. 211-215
    • Hitchcock-Bryan, S.1    Gelber, R.2    Cassady, J.R.3
  • 44
    • 0021199739 scopus 로고
    • Current status of A.L.L./A.U.L. therapy in adults
    • Hoelzer D. Current status of A.L.L./A.U.L. therapy in adults. Recent Results Cancer Res 1984; 93: 182-203
    • (1984) Recent Results Cancer Res , vol.93 , pp. 182-203
    • Hoelzer, D.1
  • 45
    • 0026083129 scopus 로고
    • Chemotherapy of adult acute lymphoblastic leukaemia
    • Stryckmans P, Debusscher L. Chemotherapy of adult acute lymphoblastic leukaemia. Baillieres Clin Haematol 1991; 4: 115-30
    • (1991) Baillieres Clin Haematol , vol.4 , pp. 115-130
    • Stryckmans, P.1    Debusscher, L.2
  • 47
    • 0017132731 scopus 로고
    • Hydroxyl-daunomycin (adriamycin) combination chemotherapy in malignant lymphoma
    • McKelvey EM, Gottlieb JA, Wilson HE, et al. Hydroxyl-daunomycin (adriamycin) combination chemotherapy in malignant lymphoma. Cancer 1976; 38: 1484
    • (1976) Cancer , vol.38 , pp. 1484
    • McKelvey, E.M.1    Gottlieb, J.A.2    Wilson, H.E.3
  • 48
    • 0018341716 scopus 로고
    • Superiority of adriamycin containing combination chemotherapy in the treatment of diffuse lymphoma: A Southwest Oncology Group Study
    • Jones SE, Grozea PN, Metz EN, et al. Superiority of adriamycin containing combination chemotherapy in the treatment of diffuse lymphoma: a Southwest Oncology Group Study. Cancer 1979; 43: 417-25
    • (1979) Cancer , vol.43 , pp. 417-425
    • Jones, S.E.1    Grozea, P.N.2    Metz, E.N.3
  • 49
    • 0021971630 scopus 로고
    • Chemotherapy with cyclophosphamide, doxorubicin, vincristine and prednisone alone or without levamisole plus BCG for malignant lymphoma: A Southwest Oncology Group Study
    • Jones SE, Grozea PN, Muller TP. Chemotherapy with cyclophosphamide, doxorubicin, vincristine and prednisone alone or without levamisole plus BCG for malignant lymphoma: a Southwest Oncology Group Study [abstract]. J Clin Oncol 1985; 3: 1318
    • (1985) J Clin Oncol , vol.3 , pp. 1318
    • Jones, S.E.1    Grozea, P.N.2    Muller, T.P.3
  • 50
    • 0020694073 scopus 로고
    • Improved complete remission rate and survival for patients with large cell lymphoma treated with chemo-immunotherapy: A Southwest Oncology Group study
    • Jones SE, Grozea PN, Metz EN. Improved complete remission rate and survival for patients with large cell lymphoma treated with chemo-immunotherapy: a Southwest Oncology Group study [abstract]. Cancer 1983; 51: 108
    • (1983) Cancer , vol.51 , pp. 108
    • Jones, S.E.1    Grozea, P.N.2    Metz, E.N.3
  • 51
    • 0028205941 scopus 로고
    • Efficacy of intensive high dose anthracycline based therapy in intermediate and high grade lymphoma
    • Zuckerman KS. Efficacy of intensive high dose anthracycline based therapy in intermediate and high grade lymphoma. Semin Oncol 1994; 21 (1): 59-64
    • (1994) Semin Oncol , vol.21 , Issue.1 , pp. 59-64
    • Zuckerman, K.S.1
  • 52
    • 0027394689 scopus 로고
    • Comparison of a standard regimen (CHOP), with three dose intensive chemotherapy regimens for advanced NHL
    • Fisher RJ, Gaynor ER, Dahlberg S, et al. Comparison of a standard regimen (CHOP), with three dose intensive chemotherapy regimens for advanced NHL. N Engl J Med 1993; 328; 1002-6
    • (1993) N Engl J Med , vol.328 , pp. 1002-1006
    • Fisher, R.J.1    Gaynor, E.R.2    Dahlberg, S.3
  • 53
    • 0028293076 scopus 로고
    • Randomised comparison of MACOP-B with CHOP in patients with intermediate grade non-Hodgkin's Lymphoma
    • Cooper IA, Wolf MW, Robertson TI, et al. Randomised comparison of MACOP-B with CHOP in patients with intermediate grade non-Hodgkin's Lymphoma. J Clin Oncol 1994; 12 (4): 769-78
    • (1994) J Clin Oncol , vol.12 , Issue.4 , pp. 769-778
    • Cooper, I.A.1    Wolf, M.W.2    Robertson, T.I.3
  • 54
    • 0026760539 scopus 로고
    • Comparison of a second generation combination chemotherapeutic regimen (m-BACOD) with a standard regimen (CHOP) for advanced diffuse non-Hodgkins Lymphoma
    • Gordon LI, Harrington D, Anderson J. Comparison of a second generation combination chemotherapeutic regimen (m-BACOD) with a standard regimen (CHOP) for advanced diffuse non-Hodgkins Lymphoma. N Engl J Med 1994 327: 1342-9
    • (1994) N Engl J Med , vol.327 , pp. 1342-1349
    • Gordon, L.I.1    Harrington, D.2    Anderson, J.3
  • 55
    • 0028115736 scopus 로고
    • Chemotherapy of non-Hodgkins aggressive lymphoma
    • Salles G, Shipp MA, Coiffer B. Chemotherapy of non-Hodgkins aggressive lymphoma. Semin Hematol 1994; 31(1): 46-69
    • (1994) Semin Hematol , vol.31 , Issue.1 , pp. 46-69
    • Salles, G.1    Shipp, M.A.2    Coiffer, B.3
  • 56
    • 1842660527 scopus 로고
    • Dose intensity (DI): Relationship to prognostic factors for diffuse large cell lymphoma (DLCL)
    • Kwak L, Olshen RA, Halpernm J, et al. Dose intensity (DI): relationship to prognostic factors for diffuse large cell lymphoma (DLCL) [abstract]. Proc Am Soc Clin Oncol 1988; 7: 226
    • (1988) Proc Am Soc Clin Oncol , vol.7 , pp. 226
    • Kwak, L.1    Olshen, R.A.2    Halpernm, J.3
  • 57
    • 0025363033 scopus 로고
    • Prognostic significance of actual dose intensity in diffuse large cell lymphoma: Results of a tree-structured survival analysis
    • Kwak LW, Halper J, Olshen RA, et al. Prognostic significance of actual dose intensity in diffuse large cell lymphoma: results of a tree-structured survival analysis. J Clin Oncol 1990; 8: 963-77
    • (1990) J Clin Oncol , vol.8 , pp. 963-977
    • Kwak, L.W.1    Halper, J.2    Olshen, R.A.3
  • 58
    • 0025865531 scopus 로고
    • Low dose ACOP-B and VABE: Weekly chemotherapy for elderly patients with advanced stage DLCL
    • O'Reilly SE, Klimo P, Connors, JM. Low dose ACOP-B and VABE: weekly chemotherapy for elderly patients with advanced stage DLCL. J Clin Oncol 1991; 9: 741-7
    • (1991) J Clin Oncol , vol.9 , pp. 741-747
    • O'Reilly, S.E.1    Klimo, P.2    Connors, J.M.3
  • 59
    • 0023137367 scopus 로고
    • Long term results of combined chemotherapy-radiotherapy approach in Hodgkin's disease - Superiority of ABVD plus radiotherapy versus MOPP plus radiotherapy
    • Santoro A, Bonadonna G, Valagussa P, et al. Long term results of combined chemotherapy-radiotherapy approach in Hodgkin's disease - superiority of ABVD plus radiotherapy versus MOPP plus radiotherapy. J Clin Oncol 1987; 5: 27-38
    • (1987) J Clin Oncol , vol.5 , pp. 27-38
    • Santoro, A.1    Bonadonna, G.2    Valagussa, P.3
  • 60
    • 0026439199 scopus 로고
    • Chemotherapy of advanced Hodgkin's disease with MOPP/ABVD or MOPP alternating with ABVD
    • Canellos GP, Anderson JR, Propert KJ, et al. Chemotherapy of advanced Hodgkin's disease with MOPP/ABVD or MOPP alternating with ABVD. N Engl J Med 1992; 327: 1478-84
    • (1992) N Engl J Med , vol.327 , pp. 1478-1484
    • Canellos, G.P.1    Anderson, J.R.2    Propert, K.J.3
  • 61
    • 0026474220 scopus 로고
    • Use of combination chemotherapy in the treatment of early stage Hodgkin's disease
    • de Vita VT, Hellman S, Rosenberg SA, editors Philadelphia: JB Lippincott Co.
    • Lango DL, De Vita VT. Use of combination chemotherapy in the treatment of early stage Hodgkin's disease. In: de Vita VT, Hellman S, Rosenberg SA, editors. Important advances in oncology. Philadelphia: JB Lippincott Co., 1992: 155-65
    • (1992) Important Advances in Oncology , pp. 155-165
    • Lango, D.L.1    De Vita, V.T.2
  • 62
    • 0024494139 scopus 로고
    • VAD Chemotherapy for refractory multiple myeloma
    • Lokhurst HM, Meuwissen OJ, Bast EJ, et al. VAD Chemotherapy for refractory multiple myeloma. Br J Haematol 1989; 71: 25-30
    • (1989) Br J Haematol , vol.71 , pp. 25-30
    • Lokhurst, H.M.1    Meuwissen, O.J.2    Bast, E.J.3
  • 63
    • 0021322023 scopus 로고
    • Effective treatment of advanced multiple myeloma refractory to alkylating agents
    • Barlogie B, Smith L, Alexanian R. Effective treatment of advanced multiple myeloma refractory to alkylating agents. N Engl J Med 1987; 310: 1353-6
    • (1987) N Engl J Med , vol.310 , pp. 1353-1356
    • Barlogie, B.1    Smith, L.2    Alexanian, R.3
  • 65
    • 0023933689 scopus 로고
    • Therapy of small cell lung cancer: A perspective on two decades of clinical research
    • Seifter EJ, Ihde DC. Therapy of small cell lung cancer: a perspective on two decades of clinical research. Semin Oncol 1988; 15: 278-99
    • (1988) Semin Oncol , vol.15 , pp. 278-299
    • Seifter, E.J.1    Ihde, D.C.2
  • 66
    • 0025898914 scopus 로고
    • Randomised trial of cyclophosphamide, doxorubicin and vincristine versus cisplatin and etoposide versus alternation of these regimens in SCLC
    • Fukuoka M, Furuse K, Saija N, et al. Randomised trial of cyclophosphamide, doxorubicin and vincristine versus cisplatin and etoposide versus alternation of these regimens in SCLC. J Natl Cancer Inst 1991; 83: 855-61
    • (1991) J Natl Cancer Inst , vol.83 , pp. 855-861
    • Fukuoka, M.1    Furuse, K.2    Saija, N.3
  • 67
    • 0026500785 scopus 로고
    • Randomised study of cyclophosphamide plus doxorubicin plus vincristine versus etoposide plus cisplatin versus alternation of these two regimens in extensive small cell lung cancer: A phase III trial of the South Eastern Cancer Study Group
    • Roth BJ, Johnson DH, Einhorn LH, et al. Randomised study of cyclophosphamide plus doxorubicin plus vincristine versus etoposide plus cisplatin versus alternation of these two regimens in extensive small cell lung cancer: a phase III trial of the South Eastern Cancer Study Group. J Clin Oncol 1992; 10: 282-91
    • (1992) J Clin Oncol , vol.10 , pp. 282-291
    • Roth, B.J.1    Johnson, D.H.2    Einhorn, L.H.3
  • 68
    • 0022409779 scopus 로고
    • VP-16 and cisplatin as first line therapy for SCLC
    • Evans WK, Shepherd FA, Feld R, et al. VP-16 and cisplatin as first line therapy for SCLC. J Clin Oncol 1985; 3: 1471-7
    • (1985) J Clin Oncol , vol.3 , pp. 1471-1477
    • Evans, W.K.1    Shepherd, F.A.2    Feld, R.3
  • 69
    • 0023684506 scopus 로고
    • Etoposide and split dose cisplatin in small cell lung cancer
    • Wilke H, Achterrath W, Schmall H, et al. Etoposide and split dose cisplatin in small cell lung cancer. Am J Clin Oncol 1988; 11: 572-8
    • (1988) Am J Clin Oncol , vol.11 , pp. 572-578
    • Wilke, H.1    Achterrath, W.2    Schmall, H.3
  • 70
    • 0022005984 scopus 로고
    • The effect of treatment in fractionated schedules with the combination of X-irradiation and six cytotoxic drugs on the RIF-1 tumour and normal mouse skin
    • Lelieveld P, Scole MA, Brow JM, et al. The effect of treatment in fractionated schedules with the combination of X-irradiation and six cytotoxic drugs on the RIF-1 tumour and normal mouse skin. Int J Radiat Oncol Biol Phys 1985; 11: 111-21
    • (1985) Int J Radiat Oncol Biol Phys , vol.11 , pp. 111-121
    • Lelieveld, P.1    Scole, M.A.2    Brow, J.M.3
  • 71
    • 0023145358 scopus 로고
    • Survival from first recurrences: Relative importance of prognostic factors in 1015 breast cancer patients
    • Clark GM, Sledge GJ, Osborne CK, et al. Survival from first recurrences: relative importance of prognostic factors in 1015 breast cancer patients. J Clin Oncol 1987; 5: 55-61
    • (1987) J Clin Oncol , vol.5 , pp. 55-61
    • Clark, G.M.1    Sledge, G.J.2    Osborne, C.K.3
  • 72
    • 0024503143 scopus 로고
    • Diverse prognosis in metastalic breast cancer: Who should be offered alternative therapies?
    • Mick R, Begg CP, Antman K, et al. Diverse prognosis in metastalic breast cancer: who should be offered alternative therapies? Breast Cancer Res Treat 1989; 13: 33-8
    • (1989) Breast Cancer Res Treat , vol.13 , pp. 33-38
    • Mick, R.1    Begg, C.P.2    Antman, K.3
  • 73
    • 0027471578 scopus 로고
    • Chemotherapy and survival in advanced breast cancers; the inclusion of doxorubicin in Cooper type regimens
    • A'Hern RP, Smith IE, Ebbs SR. Chemotherapy and survival in advanced breast cancers; the inclusion of doxorubicin in Cooper type regimens. Br J Cancer 1993; 67: 801-5
    • (1993) Br J Cancer , vol.67 , pp. 801-805
    • A'Hern, R.P.1    Smith, I.E.2    Ebbs, S.R.3
  • 74
    • 0027179964 scopus 로고
    • Design and rationale of a randomised comparison of cyclophosphamide, methotrexate and 5-fluorouracil vs 5-fluorouracil, epirubicin and cyclophosphamide in node positive premenopausal women with operable breast cancer - A trial of the International Co-operative Cancer Group
    • Wils J, Coombes RC, Marty M, et al. Design and rationale of a randomised comparison of cyclophosphamide, methotrexate and 5-fluorouracil vs 5-fluorouracil, epirubicin and cyclophosphamide in node positive premenopausal women with operable breast cancer - a trial of the International Co-operative Cancer Group. Drugs 1993; 45 Suppl. 12: 46-50
    • (1993) Drugs , vol.45 , Issue.12 SUPPL. , pp. 46-50
    • Wils, J.1    Coombes, R.C.2    Marty, M.3
  • 75
    • 0027186526 scopus 로고
    • Present status of anthracyclines in the adjuvant treatment of breast cancer
    • Hortobagyi GN, Buzdar AU. Present status of anthracyclines in the adjuvant treatment of breast cancer. Drugs 1993; 45 Suppl. 2: 4-9
    • (1993) Drugs , vol.45 , Issue.2 SUPPL. , pp. 4-9
    • Hortobagyi, G.N.1    Buzdar, A.U.2
  • 76
    • 0027102835 scopus 로고
    • Systemic therapy of advanced disease
    • Mourisden H. Systemic therapy of advanced disease. Drugs 1992; 44 Suppl. 4: 17-28
    • (1992) Drugs , vol.44 , Issue.4 SUPPL. , pp. 17-28
    • Mourisden, H.1
  • 77
    • 0023510233 scopus 로고
    • Chemotherapy versus chemoimmunotherapy (CAF v CAFVP v CMF each +/- MER) for metastatic carcinoma of the breast: A CALGB study
    • Aisner J, Weinberg V, Perloff M. Chemotherapy versus chemoimmunotherapy (CAF v CAFVP v CMF each +/- MER) for metastatic carcinoma of the breast: a CALGB study. J Clin Oncol 1987; 5: 1523-33
    • (1987) J Clin Oncol , vol.5 , pp. 1523-1533
    • Aisner, J.1    Weinberg, V.2    Perloff, M.3
  • 78
    • 0018139865 scopus 로고
    • A randomised comparative trial of adriamycin versus methotrexate in combination drug therapy
    • Bull JM, Tormey DC, Li SH, et al. A randomised comparative trial of adriamycin versus methotrexate in combination drug therapy. Cancer 1978; 41: 1649-57
    • (1978) Cancer , vol.41 , pp. 1649-1657
    • Bull, J.M.1    Tormey, D.C.2    Li, S.H.3
  • 79
    • 0344225819 scopus 로고
    • A randomised study of CAF + TAM (tamoxifen) versus CMF + TAM in metastatic breast cancer
    • Brincker H, Rose C, van der Maase H, et al. A randomised study of CAF + TAM (tamoxifen) versus CMF + TAM in metastatic breast cancer [abstract]. Proc Am Soc Clin Oncol 1984; 3: 113
    • (1984) Proc Am Soc Clin Oncol , vol.3 , pp. 113
    • Brincker, H.1    Rose, C.2    Van Der Maase, H.3
  • 80
    • 0018241926 scopus 로고
    • Adriamycin versus methotrexate in five-drug combination chemotherapy for advanced breast cancer: A randomised clinical trial
    • Muss MB, White DR, Richards F, et al. Adriamycin versus methotrexate in five-drug combination chemotherapy for advanced breast cancer: a randomised clinical trial. Cancer 1978; 42: 2141-8
    • (1978) Cancer , vol.42 , pp. 2141-2148
    • Muss, M.B.1    White, D.R.2    Richards, F.3
  • 81
    • 0021253206 scopus 로고
    • A comparison of intermittent vs continuous and of adriamycin vs MTX five drug chemotherapy for advanced breast cancer: A Cancer and Leukaemia Group B study
    • Tormey DC, Weinberg VE, Leone LA, et al. A comparison of intermittent vs continuous and of adriamycin vs MTX five drug chemotherapy for advanced breast cancer: a Cancer and Leukaemia Group B study. Am J Clin Oncol 1989; 7: 231-9
    • (1989) Am J Clin Oncol , vol.7 , pp. 231-239
    • Tormey, D.C.1    Weinberg, V.E.2    Leone, L.A.3
  • 83
    • 0009510870 scopus 로고
    • 2 D1, D8 prolongs time to progress with respect to IV CMF D1,D8 given at equi-myelosuppressive doses as first line chemotherapy of metastatic breast cancer (MBC): A randomised multinational mullicentre phase III trial
    • 2 D1, D8 prolongs time to progress with respect to IV CMF D1,D8 given at equi-myelosuppressive doses as first line chemotherapy of metastatic breast cancer (MBC): a randomised multinational mullicentre phase III trial [abstract]. Proc Am Soc Clin Oncol 1995; 14: 114
    • (1995) Proc Am Soc Clin Oncol , vol.14 , pp. 114
    • Colajori, E.1    Ackland, S.2    Anton, A.3
  • 84
    • 0023525906 scopus 로고
    • CAF in metastatic breast cancer: Standard therapy or another effective regimen
    • Hayes DF, Henderson IC. CAF in metastatic breast cancer: standard therapy or another effective regimen. J Clin Oncol 1987; 5: 1497-9
    • (1987) J Clin Oncol , vol.5 , pp. 1497-1499
    • Hayes, D.F.1    Henderson, I.C.2
  • 85
    • 0023617472 scopus 로고
    • Improving the quality of life during chemotherapy for advanced breast cancer: A comparison of intermittent and continuous treatment strategies
    • Coates A, Gebski V, Bishop JF, et al. Improving the quality of life during chemotherapy for advanced breast cancer: a comparison of intermittent and continuous treatment strategies. N Engl J Med 1987; 317: 1490-5
    • (1987) N Engl J Med , vol.317 , pp. 1490-1495
    • Coates, A.1    Gebski, V.2    Bishop, J.F.3
  • 86
    • 0019236291 scopus 로고
    • A comparison of subjective responses in a trial comparing endocrine with cytotoxic treatment in advanced carcinoma of the breast
    • Mourisden BT, Palshof T, editors. London: Pergamon
    • Baume M, Priestmon T, West RR, et al. A comparison of subjective responses in a trial comparing endocrine with cytotoxic treatment in advanced carcinoma of the breast. In: Mourisden BT, Palshof T, editors. Breast cancer: experimental and clinical aspects. London: Pergamon, 1979: 223-6
    • (1979) Breast Cancer: Experimental and Clinical Aspects , pp. 223-226
    • Baume, M.1    Priestmon, T.2    West, R.R.3
  • 87
    • 0025940676 scopus 로고
    • Interrupted versus continuous chemotherapy in patients with metastatic breast cancer
    • Muss HB, Case DL, Richards F, et al. Interrupted versus continuous chemotherapy in patients with metastatic breast cancer. N Engl J Med 1991; 325: 1342-8
    • (1991) N Engl J Med , vol.325 , pp. 1342-1348
    • Muss, H.B.1    Case, D.L.2    Richards, F.3
  • 88
    • 0025836890 scopus 로고
    • Adjuvant chemotherapy with doxorubicin plus cyclophosphamide, methotrexate and fluorouracil in the treatment of resectable breast cancer with more than three positive axillary nodes
    • Buzzoni R, Bonadonna G, Valagussa P, et al. Adjuvant chemotherapy with doxorubicin plus cyclophosphamide, methotrexate and fluorouracil in the treatment of resectable breast cancer with more than three positive axillary nodes. J Clin Oncol 1991; 9: 2134-40
    • (1991) J Clin Oncol , vol.9 , pp. 2134-2140
    • Buzzoni, R.1    Bonadonna, G.2    Valagussa, P.3
  • 89
    • 0017087722 scopus 로고
    • Ten year results of the treatment of operable breast cancer
    • Schottenfeld D, Nash AG, Robbins GF, et al. Ten year results of the treatment of operable breast cancer. Cancer 1976; 38: 1001-7
    • (1976) Cancer , vol.38 , pp. 1001-1007
    • Schottenfeld, D.1    Nash, A.G.2    Robbins, G.F.3
  • 90
    • 0026595133 scopus 로고
    • Systemic treatment of early breast cancer by hormonal, cytotoxic or immune therapy
    • Early Breast Cancer Triallists Collaborative Group. Systemic treatment of early breast cancer by hormonal, cytotoxic or immune therapy. Lancet 1992; 339: 1-15, 71-85
    • (1992) Lancet , vol.339 , pp. 1-15
  • 91
    • 0002124019 scopus 로고
    • Ten year results of the French Trial comparing adriamycin, vincristine, 5-fluorouracil and cyclophosphamide to standard CMF as adjuvant therapy for node positive breast cancer
    • Misset JL, Gil Delgado M, Challet PH, et al. Ten year results of the French Trial comparing adriamycin, vincristine, 5-fluorouracil and cyclophosphamide to standard CMF as adjuvant therapy for node positive breast cancer [abstract]. Proc Am Soc Clin Oncol 1992; 11: 55
    • (1992) Proc Am Soc Clin Oncol , vol.11 , pp. 55
    • Misset, J.L.1    Gil Delgado, M.2    Challet, P.H.3
  • 92
    • 0343046543 scopus 로고
    • Breast cancer adjuvant therapy trials of M.D. Anderson Hospital: Results of three studies
    • Salmon SE, editor. Orlando: Grune and Stratton Inc.
    • Buzdar AU, Hortobagyi GN, Kau SW, et al. Breast cancer adjuvant therapy trials of M.D. Anderson Hospital: results of three studies. In: Salmon SE, editor. Adjuvant therapy of cancer, 5th ed. Orlando: Grune and Stratton Inc., 1987: 411-8
    • (1987) Adjuvant Therapy of Cancer, 5th Ed. , pp. 411-418
    • Buzdar, A.U.1    Hortobagyi, G.N.2    Kau, S.W.3
  • 93
    • 0024522502 scopus 로고
    • Doxorubicin containing regimens for the treatment of stage II breast cancer: The national surgical adjuvant breast and bowel project experience
    • Fisher B, Redmond C, Wickerham DL, et al. Doxorubicin containing regimens for the treatment of stage II breast cancer: the national surgical adjuvant breast and bowel project experience. J Clin Oncol 1989; 7: 572-82
    • (1989) J Clin Oncol , vol.7 , pp. 572-582
    • Fisher, B.1    Redmond, C.2    Wickerham, D.L.3
  • 95
    • 0025063119 scopus 로고
    • Two months of doxorubicin-cyclophosphamide with and without reinduction chemotherapy compared with 6 months of cyclophosphamide, methotrexate and fluorouracil in positive node breast cancer patients with tamoxifen-nonresponsive tumours: Results from the National Surgical Adjuvant Breast and Bowel Project B-15
    • Fisher B, Brown AM, Dimitrov NV, et al. Two months of doxorubicin-cyclophosphamide with and without reinduction chemotherapy compared with 6 months of cyclophosphamide, methotrexate and fluorouracil in positive node breast cancer patients with tamoxifen-nonresponsive tumours: results from the National Surgical Adjuvant Breast and Bowel Project B-15. J Clin Oncol 1990; 8: 1483-96
    • (1990) J Clin Oncol , vol.8 , pp. 1483-1496
    • Fisher, B.1    Brown, A.M.2    Dimitrov, N.V.3
  • 96
    • 0009478227 scopus 로고
    • Prospective randomised comparison of cyclophosphamide, doxorubicin (adriamycin) and fluorouracil (CAF) vs. cyclophosphamide, methotrexate and fluorouracil (CMF) for breast cancer with axillary nodes: Southwestern cancer study group
    • Carpenter JT, Valez-Garcia E, Aron BS, et al. Prospective randomised comparison of cyclophosphamide, doxorubicin (adriamycin) and fluorouracil (CAF) vs. cyclophosphamide, methotrexate and fluorouracil (CMF) for breast cancer with axillary nodes: southwestern cancer study group [abstract]. Proc Am Soc Clin Oncol 1991; 10: 45
    • (1991) Proc Am Soc Clin Oncol , vol.10 , pp. 45
    • Carpenter, J.T.1    Valez-Garcia, E.2    Aron, B.S.3
  • 97
    • 1842761109 scopus 로고
    • Second interim analysis of a randomised study comparing FEC with CMF in premenopausal patients with node positive resectable breast cancer
    • Wils J, Bliss J, Marty M, et al. Second interim analysis of a randomised study comparing FEC with CMF in premenopausal patients with node positive resectable breast cancer [abstract]. Annal Oncol 1992; 3 Suppl. 5: 202
    • (1992) Annal Oncol , vol.3 , Issue.5 SUPPL. , pp. 202
    • Wils, J.1    Bliss, J.2    Marty, M.3
  • 98
    • 0025884225 scopus 로고
    • Cyclophosphamide, methotrexate and fluorouracil with and without doxorubicin in the adjuvant treatment of resectable breast cancer, with one to three positive axillary nodes
    • Moliterni A, Bonadonna G, Valagussa P, et al. Cyclophosphamide, methotrexate and fluorouracil with and without doxorubicin in the adjuvant treatment of resectable breast cancer, with one to three positive axillary nodes. J Clin Oncol 1991; 9(7): 1124-30
    • (1991) J Clin Oncol , vol.9 , Issue.7 , pp. 1124-1130
    • Moliterni, A.1    Bonadonna, G.2    Valagussa, P.3
  • 99
    • 0028813358 scopus 로고
    • Sequential or alternating doxorubicin and CMF regimens in breast cancer with more than three positive nodes: Ten year results
    • Bonadonna G, Zambetti MT, Valagussa P. Sequential or alternating doxorubicin and CMF regimens in breast cancer with more than three positive nodes: ten year results. JAMA 1995: 542-7
    • (1995) JAMA , pp. 542-547
    • Bonadonna, G.1    Zambetti, M.T.2    Valagussa, P.3
  • 100
    • 0028267517 scopus 로고
    • Late cardiac effects of adjuvant therapy: Too soon to tell
    • Shapiro CL, Henderson IC. Late cardiac effects of adjuvant therapy: too soon to tell. Ann Oncol 1994; 5: 196-8
    • (1994) Ann Oncol , vol.5 , pp. 196-198
    • Shapiro, C.L.1    Henderson, I.C.2
  • 101
    • 0028296425 scopus 로고
    • Cardiac effects following adjuvant chemotherapy and breast irradiation in operable breast cancer
    • Valagussa P, Zambetti M, Biasi S, et al. Cardiac effects following adjuvant chemotherapy and breast irradiation in operable breast cancer. Ann Oncol 1994; 5: 196-8
    • (1994) Ann Oncol , vol.5 , pp. 196-198
    • Valagussa, P.1    Zambetti, M.2    Biasi, S.3
  • 102
    • 1842761112 scopus 로고
    • Cyclophosphamide, methotrexate, 5-fluorouracil (CMF), versus 5-fluorouracil, epirubicin, cyclophosphamide chemotherapy in pre-menopausal females with node positive breast cancer: Results of a randomised trial
    • Marty M, Bliss J, Coombes R, et al. Cyclophosphamide, methotrexate, 5-fluorouracil (CMF), versus 5-fluorouracil, epirubicin, cyclophosphamide chemotherapy in pre-menopausal females with node positive breast cancer: results of a randomised trial [abstract]. Proc Am Soc Clin Oncol 1994; 13
    • (1994) Proc Am Soc Clin Oncol , pp. 13
    • Marty, M.1    Bliss, J.2    Coombes, R.3
  • 104
    • 0024246020 scopus 로고
    • Dose response in the treatment of breast cancer: A critical review
    • Henderson IC, Hayes DF, Gelman R. Dose response in the treatment of breast cancer: a critical review. J Clin Oncol 1988; 6: 1501-15
    • (1988) J Clin Oncol , vol.6 , pp. 1501-1515
    • Henderson, I.C.1    Hayes, D.F.2    Gelman, R.3
  • 105
    • 0018931869 scopus 로고
    • Dose, a critical factor in cancer chemotherapy
    • Frei E, Canellos GP. Dose, a critical factor in cancer chemotherapy. Am J Med 1980; 69: 585-94
    • (1980) Am J Med , vol.69 , pp. 585-594
    • Frei, E.1    Canellos, G.P.2
  • 106
    • 0015362572 scopus 로고
    • Survival of haematopoietic and leukaemia colony forming cells in-vitro following the administration of daunorubicin or adriamycin
    • Razak E, Valeriote F, Vietti T. Survival of haematopoietic and leukaemia colony forming cells in-vitro following the administration of daunorubicin or adriamycin. Cancer Res 1972; 32: 1496-500
    • (1972) Cancer Res , vol.32 , pp. 1496-1500
    • Razak, E.1    Valeriote, F.2    Vietti, T.3
  • 107
    • 0018090494 scopus 로고
    • Amputation and adriamycin in primary osteosarcoma: A five year report
    • Cortes EP, Holland JF, Glidewell O. Amputation and adriamycin in primary osteosarcoma: a five year report. Cancer Treat Rep 1978; 62: 271-7
    • (1978) Cancer Treat Rep , vol.62 , pp. 271-277
    • Cortes, E.P.1    Holland, J.F.2    Glidewell, O.3
  • 108
    • 0019979989 scopus 로고
    • Activity of daunorubicin vs adriamycin induction and monthly vs bimonthly maintenance in AML
    • Yates JW, Glidewell O, Wiernik P, et al. Activity of daunorubicin vs adriamycin induction and monthly vs bimonthly maintenance in AML. Blood 1982; 60: 454-62
    • (1982) Blood , vol.60 , pp. 454-462
    • Yates, J.W.1    Glidewell, O.2    Wiernik, P.3
  • 109
    • 0022921982 scopus 로고
    • Analysis of dose intensity for adjuvant chemotherapy trials in stage II breast cancer
    • Hryniuk W, Levine MN. Analysis of dose intensity for adjuvant chemotherapy trials in stage II breast cancer. J Clin Oncol 1986; 4: 1162-70
    • (1986) J Clin Oncol , vol.4 , pp. 1162-1170
    • Hryniuk, W.1    Levine, M.N.2
  • 110
    • 0021744793 scopus 로고
    • The importance of dose intensity in chemotherapy of metastatic breast cancer
    • Hryniuk W, Bush H. The importance of dose intensity in chemotherapy of metastatic breast cancer. J Clin Oncol 1984; 2: 1281-8
    • (1984) J Clin Oncol , vol.2 , pp. 1281-1288
    • Hryniuk, W.1    Bush, H.2
  • 111
    • 0025337577 scopus 로고
    • How to improve cytotoxic therapy in advanced breast cancer
    • Bastholt HL, Mourisden HT. How to improve cytotoxic therapy in advanced breast cancer. Acta Oncol 1990; 29: 349-55
    • (1990) Acta Oncol , vol.29 , pp. 349-355
    • Bastholt, H.L.1    Mourisden, H.T.2
  • 112
    • 0028225388 scopus 로고
    • A pilot study of accelerated cyclophosphamide/epirubicin and 5-fluorouracil plus GCSF as adjuvant therapy in early breast cancer
    • Del Mastro L, Garrone O, Sertoli MR, et al. A pilot study of accelerated cyclophosphamide/epirubicin and 5-fluorouracil plus GCSF as adjuvant therapy in early breast cancer. Eur J Cancer 1994; 30A (5): 606-10
    • (1994) Eur J Cancer , vol.30 A , Issue.5 , pp. 606-610
    • Del Mastro, L.1    Garrone, O.2    Sertoli, M.R.3
  • 113
    • 0027483443 scopus 로고
    • High dose, dose intensive chemotherapy with doxorubicin and cyclophosphamide for the treatment of advanced breast cancer
    • Ferguson JE, Dodwell DJ, Seymour AM, et al. High dose, dose intensive chemotherapy with doxorubicin and cyclophosphamide for the treatment of advanced breast cancer. Br J Cancer 1993; 67: 825-9
    • (1993) Br J Cancer , vol.67 , pp. 825-829
    • Ferguson, J.E.1    Dodwell, D.J.2    Seymour, A.M.3
  • 114
    • 0028269421 scopus 로고
    • High-dose doxorubicin, etoposide and cyclophosphamide with stem cell reinfusion in patients with metastatic or high-risk primary breast cancer
    • Somlo G, Doroshow JH, Forman SJ, et al. High-dose doxorubicin, etoposide and cyclophosphamide with stem cell reinfusion in patients with metastatic or high-risk primary breast cancer. Cancer 1994; 73: 1678-85
    • (1994) Cancer , vol.73 , pp. 1678-1685
    • Somlo, G.1    Doroshow, J.H.2    Forman, S.J.3
  • 115
    • 0024413669 scopus 로고
    • Epirubicin high dose therapy in advanced breast cancer: Preliminary clinical data
    • Neri B, Pacini P, Bartalucci S, et al. Epirubicin high dose therapy in advanced breast cancer: preliminary clinical data. Int J Clin Pharmacol Ther 1989; 27: 338-91
    • (1989) Int J Clin Pharmacol Ther , vol.27 , pp. 338-391
    • Neri, B.1    Pacini, P.2    Bartalucci, S.3
  • 116
    • 1842761110 scopus 로고
    • Epirubicin as first line chemotherapy in disseminated breast cancer
    • Carmo-Pereira J, Costa EO, Henriques E, et al. Epirubicin as first line chemotherapy in disseminated breast cancer. Cancer Invest 1993; 11: 106-12
    • (1993) Cancer Invest , vol.11 , pp. 106-112
    • Carmo-Pereira, J.1    Costa, E.O.2    Henriques, E.3
  • 117
    • 0028268507 scopus 로고
    • Evaluation of the importance and relevance of dose intensity using epirubicin and cyclophosphamide in metastatic breast cancer: Interim analysis of a prospective randomised trial
    • Marschner N, Kreinberg R, Souchan R, et al. Evaluation of the importance and relevance of dose intensity using epirubicin and cyclophosphamide in metastatic breast cancer: interim analysis of a prospective randomised trial. Semin Oncol 1994; 21: 10-6
    • (1994) Semin Oncol , vol.21 , pp. 10-16
    • Marschner, N.1    Kreinberg, R.2    Souchan, R.3
  • 118
    • 0028791871 scopus 로고
    • Phase II study of high dose epirubicin in combination with cyclophosphamide in patients with advanced breast cancer
    • Levi JA, Beith JM, Snyder RD, et al. Phase II study of high dose epirubicin in combination with cyclophosphamide in patients with advanced breast cancer. Aust NZJ Med 1995; 25; 474-8
    • (1995) Aust NZJ Med , vol.25 , pp. 474-478
    • Levi, J.A.1    Beith, J.M.2    Snyder, R.D.3
  • 119
    • 0027288857 scopus 로고
    • Dose-response relationship of epirubicin-based first-line chemotherapy for advanced breast cancer: Prospective randomised trial
    • Focan C, Andrien JM, Closon M, et al. Dose-response relationship of epirubicin-based first-line chemotherapy for advanced breast cancer: prospective randomised trial. J Clin Oncol 1993: 11; 1253-63
    • (1993) J Clin Oncol , vol.11 , pp. 1253-1263
    • Focan, C.1    Andrien, J.M.2    Closon, M.3
  • 120
    • 0026032603 scopus 로고
    • Epirubicin at two dose level with prednisolone as treatment for advanced breast cancer: The results of a randomised clinical trial
    • Habeshaw T, Jones PR, Stallard S, et al. Epirubicin at two dose level with prednisolone as treatment for advanced breast cancer: the results of a randomised clinical trial. J Clin Oncol 1991; 9: 295-304
    • (1991) J Clin Oncol , vol.9 , pp. 295-304
    • Habeshaw, T.1    Jones, P.R.2    Stallard, S.3
  • 121
    • 0029116891 scopus 로고
    • High dose chemotherapy with haematopoietic rescue as primary treatment for metastatic breast cancer: A randomised trial
    • Bezwoda WR, Seymour L, Dansey RD. High dose chemotherapy with haematopoietic rescue as primary treatment for metastatic breast cancer: a randomised trial. J Clin Oncol 1995; 13: 2483-9
    • (1995) J Clin Oncol , vol.13 , pp. 2483-2489
    • Bezwoda, W.R.1    Seymour, L.2    Dansey, R.D.3
  • 122
    • 0028274962 scopus 로고
    • Dose and dose intensity of adjuvant chemotherapy for stage II node positive breast cancer
    • Wood WC, Budman DR, Karzun MS, et al. Dose and dose intensity of adjuvant chemotherapy for stage II node positive breast cancer. N Engl J Med 1994; 330 (18): 1253-9
    • (1994) N Engl J Med , vol.330 , Issue.18 , pp. 1253-1259
    • Wood, W.C.1    Budman, D.R.2    Karzun, M.S.3
  • 123
    • 0028282005 scopus 로고
    • Dose escalating induction chemotherapy supported by lenograstim preceding high dose consolidation chemotherapy for advanced breast cancer
    • Van Hoel MEHM, Baumann I, Lange C, et al. Dose escalating induction chemotherapy supported by lenograstim preceding high dose consolidation chemotherapy for advanced breast cancer. Ann Oncol 1994 5: 217-24
    • (1994) Ann Oncol , vol.5 , pp. 217-224
    • Van Hoel, M.E.H.M.1    Baumann, I.2    Lange, C.3
  • 124
    • 0028999640 scopus 로고
    • Adjuvant treatment of high risk breast cancer using multicycle high dose chemotherapy and filgrastim-mobilised peripheral blood progenitor cells
    • Basser RL, To LB, Begley G, et al. Adjuvant treatment of high risk breast cancer using multicycle high dose chemotherapy and filgrastim-mobilised peripheral blood progenitor cells. Clin Cancer Res 1995; 1: 715-21
    • (1995) Clin Cancer Res , vol.1 , pp. 715-721
    • Basser, R.L.1    To, L.B.2    Begley, G.3
  • 125
    • 0028354305 scopus 로고
    • C erb B-2 expression and response to adjuvant therapy in women with node positive early breast cancer
    • Muss HB, Thor AD, Berry DA, et al. C erb B-2 expression and response to adjuvant therapy in women with node positive early breast cancer. N Engl J Med 1994; 330: 1260-6
    • (1994) N Engl J Med , vol.330 , pp. 1260-1266
    • Muss, H.B.1    Thor, A.D.2    Berry, D.A.3
  • 126
    • 0028197512 scopus 로고
    • Dose intensive chemotherapy with cytokine support
    • Green M. Dose intensive chemotherapy with cytokine support. Semin Oncol 1994; 21 Suppl. 1: 1-6
    • (1994) Semin Oncol , vol.21 , Issue.1 SUPPL. , pp. 1-6
    • Green, M.1
  • 127
    • 0028707653 scopus 로고
    • Combination chemotherapy with taxol (paclitaxel) in metastatic breast cancer
    • Holmes FA. Combination chemotherapy with taxol (paclitaxel) in metastatic breast cancer. Ann Oncol 1994; 5 Suppl. 6: 523-2
    • (1994) Ann Oncol , vol.5 , Issue.6 SUPPL. , pp. 523-532
    • Holmes, F.A.1
  • 128
    • 0028877036 scopus 로고
    • Paclitaxel by 3-hour infusion in combination with bolus doxorubicin in women with untreated metastatic breast cancer: High antitumour efficiency and cardiac effects in a dose-finding and sequence-finding study
    • Gianni L, Munzone E, Capri G, et al. Paclitaxel by 3-hour infusion in combination with bolus doxorubicin in women with untreated metastatic breast cancer: high antitumour efficiency and cardiac effects in a dose-finding and sequence-finding study. J Clin Oncol 1995; 13(11): 2688-99
    • (1995) J Clin Oncol , vol.13 , Issue.11 , pp. 2688-2699
    • Gianni, L.1    Munzone, E.2    Capri, G.3
  • 129
    • 9044224027 scopus 로고    scopus 로고
    • Phase I/II study of 72 hour infusional paclitaxel and doxorubicin with granulocyte stimulating factor in patients with metastatic breast cancer
    • Fisherman JS, Cowan KH, Noone M, et al. Phase I/II study of 72 hour infusional paclitaxel and doxorubicin with granulocyte stimulating factor in patients with metastatic breast cancer. J Clin Oncol 1996; 14 (3): 774-82
    • (1996) J Clin Oncol , vol.14 , Issue.3 , pp. 774-782
    • Fisherman, J.S.1    Cowan, K.H.2    Noone, M.3
  • 130
    • 1842811543 scopus 로고
    • Cardiac function in breast cancer patients given paclitaxel (Taxol) by 3 hour infusion, and previous or concomitant doxorubicin
    • Munzone E, Gianni L, Capri G, et al. Cardiac function in breast cancer patients given paclitaxel (Taxol) by 3 hour infusion, and previous or concomitant doxorubicin [abstract]. Proc Am Soc Clin Oncol 1995; 14: 128
    • (1995) Proc Am Soc Clin Oncol , vol.14 , pp. 128
    • Munzone, E.1    Gianni, L.2    Capri, G.3
  • 131
    • 0029932522 scopus 로고    scopus 로고
    • Activity and safety of epirubicin plus paclitaxel in advanced breast cancer
    • Conte P, Michelotti A, Baldini E et al. Activity and safety of epirubicin plus paclitaxel in advanced breast cancer. Semin Oncol 1996; 23 Suppl. 1: 28-32
    • (1996) Semin Oncol , vol.23 , Issue.1 SUPPL. , pp. 28-32
    • Conte, P.1    Michelotti, A.2    Baldini, E.3
  • 132
    • 0000305022 scopus 로고    scopus 로고
    • Phase II study of paclitaxel and 4.epi-doxorubicin (epirubicin) as first line therapy in patients with metastatic breast cancer
    • Lück HJ, Thomssen C, du Bois A. Phase II study of paclitaxel and 4.epi-doxorubicin (epirubicin) as first line therapy in patients with metastatic breast cancer [abstract]. Proc Am Soc Clin Oncol 1996; 15: 120
    • (1996) Proc Am Soc Clin Oncol , vol.15 , pp. 120
    • Lück, H.J.1    Thomssen, C.2    Du Bois, A.3
  • 133
    • 0017744029 scopus 로고
    • Chemotherapy of advanced soft-tissue sarcomas in adults
    • Pinede HM, Kenis Y. Chemotherapy of advanced soft-tissue sarcomas in adults. Cancer Treat Rev 1977; 4: 67-86
    • (1977) Cancer Treat Rev , vol.4 , pp. 67-86
    • Pinede, H.M.1    Kenis, Y.2
  • 134
    • 0016749096 scopus 로고
    • An overview of studies of adriamycin (NSC-123127) in the United States
    • Blum RH. An overview of studies of adriamycin (NSC-123127) in the United States. Cancer Chemother Rep 1975; 6: 247-51
    • (1975) Cancer Chemother Rep , vol.6 , pp. 247-251
    • Blum, R.H.1
  • 135
    • 0029005580 scopus 로고
    • Doxorubicin versus CYVADIC versus doxorubicin plus ifosfamide in first-line treatment of advanced soft tissue sarcomas: A randomised study of the European Organisation for the Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group
    • Santoro A, Tursz T, Mourisden H, et al. Doxorubicin versus CYVADIC versus doxorubicin plus ifosfamide in first-line treatment of advanced soft tissue sarcomas: a randomised study of the European Organisation for the Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group. J Clin Oncol 1995; 13: 1537-45
    • (1995) J Clin Oncol , vol.13 , pp. 1537-1545
    • Santoro, A.1    Tursz, T.2    Mourisden, H.3
  • 136
    • 0028067566 scopus 로고
    • Salvage therapy for soft tissue sarcomas
    • Elias A. Salvage therapy for soft tissue sarcomas. Semin Oncol 1994; 21 (4 Suppl. 7): 76-81
    • (1994) Semin Oncol , vol.21 , Issue.4-7 SUPPL. , pp. 76-81
    • Elias, A.1
  • 137
    • 0026326203 scopus 로고
    • Adjuvant chemotherapy of high grade sarcoma of the extremity: Reported results of the Multi-Institutional Osteosarcoma Study
    • Link MP, Goorin AM, Horowitz M. Adjuvant chemotherapy of high grade sarcoma of the extremity: reported results of the Multi-Institutional Osteosarcoma Study. Clin Orthop 1991; 270: 8-14
    • (1991) Clin Orthop , vol.270 , pp. 8-14
    • Link, M.P.1    Goorin, A.M.2    Horowitz, M.3
  • 138
    • 0023125939 scopus 로고
    • Adjuvant chemotherapy for osteosarcoma: A randomised prospective trial
    • Eilber F, Guilano A,. Eckardt J. Adjuvant chemotherapy for osteosarcoma: a randomised prospective trial. J Clin Oncol 1987; 5: 21-6
    • (1987) J Clin Oncol , vol.5 , pp. 21-26
    • Eilber, F.1    Guilano, A.2    Eckardt, J.3
  • 139
    • 0023723063 scopus 로고
    • Chemotherapy of advanced gastric cancer: Present status, future prospects
    • Macdonald JS, Gohmann JJ. Chemotherapy of advanced gastric cancer: present status, future prospects. Semin Oncol 1988; 15 Suppl. 4: 42-9
    • (1988) Semin Oncol , vol.15 , Issue.4 SUPPL. , pp. 42-49
    • Macdonald, J.S.1    Gohmann, J.J.2
  • 140
    • 0018931354 scopus 로고
    • 5-fluorouracil, doxorubicin and mitomycin (FAM) combination chemotherapy for advanced gastric cancer
    • Macdonald JS, Scheers PS, Wadley PV, et al. 5-fluorouracil, doxorubicin and mitomycin (FAM) combination chemotherapy for advanced gastric cancer. Ann Intern Med 1980; 93: 533-6
    • (1980) Ann Intern Med , vol.93 , pp. 533-536
    • Macdonald, J.S.1    Scheers, P.S.2    Wadley, P.V.3
  • 141
    • 0027537350 scopus 로고
    • Combined doxorubicin and alpha-interferon therapy of advanced hepatocellular carcinoma
    • Kardinal CG, Moertel CG, Wieand HS, et al. Combined doxorubicin and alpha-interferon therapy of advanced hepatocellular carcinoma. Cancer 1993; 71 (7): 2187-90
    • (1993) Cancer , vol.71 , Issue.7 , pp. 2187-2190
    • Kardinal, C.G.1    Moertel, C.G.2    Wieand, H.S.3
  • 142
    • 0026333919 scopus 로고
    • Chemotherapy for invasive thymoma: A thirteen year experience
    • Fornasiera A, Danile O, Ghiotto C, et al. Chemotherapy for invasive thymoma: a thirteen year experience. Cancer 1991; 68: 30-3
    • (1991) Cancer , vol.68 , pp. 30-33
    • Fornasiera, A.1    Danile, O.2    Ghiotto, C.3
  • 143
    • 0017893372 scopus 로고
    • Comparison of adriamycin with cyclophosphamide in patients with advanced endometrial cancer
    • Horton J, Begg CB, Arsenault J, et al. Comparison of adriamycin with cyclophosphamide in patients with advanced endometrial cancer. Cancer Treat Rep 1978; 62: 159-61
    • (1978) Cancer Treat Rep , vol.62 , pp. 159-161
    • Horton, J.1    Begg, C.B.2    Arsenault, J.3
  • 144
    • 0018770793 scopus 로고
    • Phase II trial of advanced or recurrent endometrial cancer: A Gynaecologic Oncology Group Study
    • Thigpen JT, Buchsbaum HJ, Mangon C, et al. Phase II trial of advanced or recurrent endometrial cancer: a Gynaecologic Oncology Group Study. Cancer Treat Rep 1979; 63: 21-7
    • (1979) Cancer Treat Rep , vol.63 , pp. 21-27
    • Thigpen, J.T.1    Buchsbaum, H.J.2    Mangon, C.3
  • 145
    • 0000154296 scopus 로고
    • A randomised comparison ofl adnamycin with or without cyclophosphamide in the treatment of advanced or recurrent endometlrial cancer
    • Thigpen JT, Blessing J, Di Saia P, et al. A randomised comparison ofl adnamycin with or without cyclophosphamide in the treatment of advanced or recurrent endometlrial cancer [abstract]. Proc Am Soc Clin Oncol 1985; 4: 15
    • (1985) Proc Am Soc Clin Oncol , vol.4 , pp. 15
    • Thigpen, J.T.1    Blessing, J.2    Di Saia, P.3
  • 146
    • 0017656375 scopus 로고
    • Doxorubicin-cyclophosphamide: Effective chemotherapy for advanced endometrial adenocarcinoma
    • Muggia FM, Chia G, Reed LJ, et al. Doxorubicin-cyclophosphamide: effective chemotherapy for advanced endometrial adenocarcinoma. Am J Obstet Gynecol 1977; 128: 314-9
    • (1977) Am J Obstet Gynecol , vol.128 , pp. 314-319
    • Muggia, F.M.1    Chia, G.2    Reed, L.J.3
  • 147
    • 0025073788 scopus 로고
    • Treatment of advanced-recurrent adenocarcinoma of the endometrium with doxorubicin and cyclophosphamide
    • Campora E, Vidali A, Mammolitis S, et al. Treatment of advanced-recurrent adenocarcinoma of the endometrium with doxorubicin and cyclophosphamide. Eur J Gynaecol Oncol 1990; 11: 183-7
    • (1990) Eur J Gynaecol Oncol , vol.11 , pp. 183-187
    • Campora, E.1    Vidali, A.2    Mammolitis, S.3
  • 148
    • 0028948614 scopus 로고
    • Impact of doxorubicin on survival in advanced ovarian cancer
    • A'Hern RP, Gore ME. Impact of doxorubicin on survival in advanced ovarian cancer. J Clin Oncol 1995; 13: 726-32
    • (1995) J Clin Oncol , vol.13 , pp. 726-732
    • A'Hern, R.P.1    Gore, M.E.2
  • 149
    • 0015990773 scopus 로고
    • Adriamycin: A new anthracycline drug with significant clinical activity
    • Blum RH, Carter SK. Adriamycin: a new anthracycline drug with significant clinical activity. Ann Intern Med 1974; 80: 249-59
    • (1974) Ann Intern Med , vol.80 , pp. 249-259
    • Blum, R.H.1    Carter, S.K.2
  • 150
    • 1842660498 scopus 로고
    • Secondary leukaemia following adjuvant doxorubicin containing chemotherapy for stage II or III breast cancer
    • Buzdar A, Ivaniec J, Kau S, et al. Secondary leukaemia following adjuvant doxorubicin containing chemotherapy for stage II or III breast cancer [abstract]. Proc Am Soc Clin Oncol 1991; 10: 59
    • (1991) Proc Am Soc Clin Oncol , vol.10 , pp. 59
    • Buzdar, A.1    Ivaniec, J.2    Kau, S.3
  • 151
    • 0027056223 scopus 로고
    • Acute monocytic or myelomonocytic leukaemia with balanced chromosome translocations to band 11q23 after therapy with 4 epi-doxorubicin and cisplatin or cyclophosphamide for breast cancer
    • Pedersen-Bjergaard J, Sigsgoord T, Nielsen D, et al. Acute monocytic or myelomonocytic leukaemia with balanced chromosome translocations to band 11q23 after therapy with 4 epi-doxorubicin and cisplatin or cyclophosphamide for breast cancer. J Clin Oncol 1992; 10: 1444-51
    • (1992) J Clin Oncol , vol.10 , pp. 1444-1451
    • Pedersen-Bjergaard, J.1    Sigsgoord, T.2    Nielsen, D.3
  • 152
    • 0028863756 scopus 로고
    • Acute promyelocytic leukaemia with t(15,17) following inhibitor of DNA topoisomerase II
    • Pederson-Bjergaard J. Acute promyelocytic leukaemia with t(15,17) following inhibitor of DNA topoisomerase II [editorial] Ann Oncol 1995; 6: 751-3
    • (1995) Ann Oncol , vol.6 , pp. 751-753
    • Pederson-Bjergaard, J.1
  • 153
    • 24444456781 scopus 로고
    • Leukaemogenic potential of adjuvant chemotherapy for early stage breast cancer: The Eastern Cooperative Oncology Group (ECOG) experience
    • Tallman M, Gray B, Bennet J, et al. Leukaemogenic potential of adjuvant chemotherapy for early stage breast cancer: the Eastern Cooperative Oncology Group (ECOG) experience [abstract]. Blood 1993; 82 Suppl. 10: 48a
    • (1993) Blood , vol.82 , Issue.10 SUPPL.
    • Tallman, M.1    Gray, B.2    Bennet, J.3
  • 154
    • 0027270027 scopus 로고
    • Therapy related leukaemia: What is the role of 4 epi doxorubicin?
    • Riggi M, Riva M. Therapy related leukaemia: what is the role of 4 epi doxorubicin? J Clin Oncol 1993; 11: 1430-1
    • (1993) J Clin Oncol , vol.11 , pp. 1430-1431
    • Riggi, M.1    Riva, M.2
  • 156
    • 0025051505 scopus 로고
    • Doxorubicin cardiotoxicity: Analysis of prevailing hypotheses
    • Olson RD, Mushlin PS. Doxorubicin cardiotoxicity: analysis of prevailing hypotheses. FASEB J 1990; 4: 3076-86
    • (1990) FASEB J , vol.4 , pp. 3076-3086
    • Olson, R.D.1    Mushlin, P.S.2
  • 157
  • 158
    • 0017354816 scopus 로고
    • Daunomycin-induced cardiotoxicity in children and adults: A review of 110 cases
    • Von Hoff DD, Rozeneweig M, Layard M. Daunomycin-induced cardiotoxicity in children and adults: a review of 110 cases. Am J Med 1977; 62: 200-8
    • (1977) Am J Med , vol.62 , pp. 200-208
    • Von Hoff, D.D.1    Rozeneweig, M.2    Layard, M.3
  • 159
    • 0019413926 scopus 로고
    • Anthracycline-associated cardiac and renal damage in rabbits: Evidence for mediation by vasoactive substances
    • Bristow MR, Minobe WA, Billingham ME, et al. Anthracycline-associated cardiac and renal damage in rabbits: evidence for mediation by vasoactive substances. Lab Invest 1981; 45: 157-68
    • (1981) Lab Invest , vol.45 , pp. 157-168
    • Bristow, M.R.1    Minobe, W.A.2    Billingham, M.E.3
  • 161
    • 0018716636 scopus 로고
    • Risk factors for doxorubicin-induced congestive cardiac failure
    • Von Hoff DD, Layard MW, Basa P, et al. Risk factors for doxorubicin-induced congestive cardiac failure. Ann Intern Med 1979; 91: 710-7
    • (1979) Ann Intern Med , vol.91 , pp. 710-717
    • Von Hoff, D.D.1    Layard, M.W.2    Basa, P.3
  • 162
    • 0021878134 scopus 로고
    • Early and delayed clinical cardiotoxicity of doxorubicin
    • Buzdar AV, Marcus C, Smith TL, et al. Early and delayed clinical cardiotoxicity of doxorubicin. Cancer 1985; 55: 2761-5
    • (1985) Cancer , vol.55 , pp. 2761-2765
    • Buzdar, A.V.1    Marcus, C.2    Smith, T.L.3
  • 164
    • 0025850827 scopus 로고
    • Cardiac toxicity 4-20 years after completing anthracycline therapy
    • Steinherz LJ, Steinherz PG, Tan CT. Cardiac toxicity 4-20 years after completing anthracycline therapy. JAMA 1991; 266: 1672-7
    • (1991) JAMA , vol.266 , pp. 1672-1677
    • Steinherz, L.J.1    Steinherz, P.G.2    Tan, C.T.3
  • 165
    • 0030048913 scopus 로고    scopus 로고
    • Anthracycline cardiac toxicity by dexrazoxane: Breakthrough of a barrier - Sharpens anti-tumour profile and therapeutic index
    • Helleman K. Anthracycline cardiac toxicity by dexrazoxane: breakthrough of a barrier - sharpens anti-tumour profile and therapeutic index [editorial]. J Clin Oncol 1996; 14(2): 332-3
    • (1996) J Clin Oncol , vol.14 , Issue.2 , pp. 332-333
    • Helleman, K.1
  • 166
    • 0028989408 scopus 로고
    • Female sex and higher drug close as risk factors for late cardiotoxic effects of doxorubicin therapy for childhood cancer
    • Lipshultz S, Lipsitz S, Mone SM. Female sex and higher drug close as risk factors for late cardiotoxic effects of doxorubicin therapy for childhood cancer. N Engl J Med 1995; 332: 1738-43
    • (1995) N Engl J Med , vol.332 , pp. 1738-1743
    • Lipshultz, S.1    Lipsitz, S.2    Mone, S.M.3
  • 167
    • 1842710657 scopus 로고
    • Radiation induced myocardial changes
    • Muggia FM, Green MD, Speyer JL, editors. Baltimore: The John Hopkins University Press
    • Renzi RS, Straus KL, Glatstein E. Radiation induced myocardial changes. In: Muggia FM, Green MD, Speyer JL, editors. Cancer treatment and the heart. 1st ed. Baltimore: The John Hopkins University Press, 1992: 287-328
    • (1992) Cancer Treatment and the Heart. 1st Ed. , pp. 287-328
    • Renzi, R.S.1    Straus, K.L.2    Glatstein, E.3
  • 168
    • 0028000315 scopus 로고
    • Anthracyclines: Cardiotoxicity and its prevention
    • Hale JP, Lewis IJ. Anthracyclines: cardiotoxicity and its prevention. Arch Dis Child 1994; 71: 457-62
    • (1994) Arch Dis Child , vol.71 , pp. 457-462
    • Hale, J.P.1    Lewis, I.J.2
  • 169
    • 0021053071 scopus 로고
    • Sensitivity and specificity of radionucleotide ejection fraction in doxorubicin cardiotoxicity
    • McKillop JH, Brista MR, Gorus ML, et al. Sensitivity and specificity of radionucleotide ejection fraction in doxorubicin cardiotoxicity. Am Heart J 1983; 106: 1048-56
    • (1983) Am Heart J , vol.106 , pp. 1048-1056
    • McKillop, J.H.1    Brista, M.R.2    Gorus, M.L.3
  • 170
    • 0022375785 scopus 로고
    • Radionuclide ventriculography for the evaluation and prevention of doxorubicin cardiotoxicity
    • Steinberg JS, Wasserman AG. Radionuclide ventriculography for the evaluation and prevention of doxorubicin cardiotoxicity. Clin Ther 1985; 7: 660-7
    • (1985) Clin Ther , vol.7 , pp. 660-667
    • Steinberg, J.S.1    Wasserman, A.G.2
  • 171
    • 0021799404 scopus 로고
    • Doxorubicin hydrochloride (adriamycin) cardiotoxicity evaluated by sequential radionucleotide angiocardiography
    • Piver MS, Marchetti DI, Parthasarathy KL, et al. Doxorubicin hydrochloride (adriamycin) cardiotoxicity evaluated by sequential radionucleotide angiocardiography. Cancer 1985; 56: 76-80
    • (1985) Cancer , vol.56 , pp. 76-80
    • Piver, M.S.1    Marchetti, D.I.2    Parthasarathy, K.L.3
  • 172
    • 0018141890 scopus 로고
    • Serial studies of cardiac function in patients receiving adriamycin
    • Henderson JC, Sloss LJ, Jaffe N. Serial studies of cardiac function in patients receiving adriamycin. Cancer Treat Rep 1978; 62: 923-9
    • (1978) Cancer Treat Rep , vol.62 , pp. 923-929
    • Henderson, J.C.1    Sloss, L.J.2    Jaffe, N.3
  • 173
    • 0021356510 scopus 로고
    • A comparison of cardiac biopsy grades and ejection fraction estimation in patients receiving adriamycin
    • Ewer MS, Ali MK, Mackay B. A comparison of cardiac biopsy grades and ejection fraction estimation in patients receiving adriamycin. J Clin Oncol 1985; 2: 112-7
    • (1985) J Clin Oncol , vol.2 , pp. 112-117
    • Ewer, M.S.1    Ali, M.K.2    Mackay, B.3
  • 174
    • 0017199039 scopus 로고
    • Studies on adriamycin using a weekly regimen demonstrating its clinical effectiveness and lack of cardiac toxicity
    • Weiss AJ, Metter GE, Fletcher WS. Studies on adriamycin using a weekly regimen demonstrating its clinical effectiveness and lack of cardiac toxicity. Cancer Treal Rep 1976; 60: 813-22
    • (1976) Cancer Treal Rep , vol.60 , pp. 813-822
    • Weiss, A.J.1    Metter, G.E.2    Fletcher, W.S.3
  • 175
    • 0021063443 scopus 로고
    • Reduced cardiotoxicity of doxorubicin on a weekly schedule: Assessment by endomyocardial biopsy
    • Torti FM, Bristow MM, Howes AE. Reduced cardiotoxicity of doxorubicin on a weekly schedule: assessment by endomyocardial biopsy. Ann Intern Med 1985; 99: 745-9
    • (1985) Ann Intern Med , vol.99 , pp. 745-749
    • Torti, F.M.1    Bristow, M.M.2    Howes, A.E.3
  • 176
    • 0020038042 scopus 로고
    • Reduction of cardiotoxicity by prolonged continuous intra-venous infusion
    • Legha SS, Benjamin RS, Mackay B, et al. Reduction of cardiotoxicity by prolonged continuous intra-venous infusion. Ann Intern Med 1982; 96: 133-9
    • (1982) Ann Intern Med , vol.96 , pp. 133-139
    • Legha, S.S.1    Benjamin, R.S.2    Mackay, B.3
  • 177
    • 0026709749 scopus 로고
    • Infusional anthracyclines: Is slower better? if so why?
    • Workman P. Infusional anthracyclines: is slower better? If so why? Ann Oncol 1992; 3: 591-4
    • (1992) Ann Oncol , vol.3 , pp. 591-594
    • Workman, P.1
  • 178
    • 0024546425 scopus 로고
    • Decreased cardiac toxicity of doxorubicin administered by continuous intravenous infusion in combination chemotherapy for metastatic breast cancer
    • Hortobagyi GN, Frye RN, Buzdar AU. Decreased cardiac toxicity of doxorubicin administered by continuous intravenous infusion in combination chemotherapy for metastatic breast cancer. Cancer 1989; 63: 37-45
    • (1989) Cancer , vol.63 , pp. 37-45
    • Hortobagyi, G.N.1    Frye, R.N.2    Buzdar, A.U.3
  • 179
    • 0015337898 scopus 로고
    • Prevention of cardiotoxic effects of adriamycin and daunomycin in the isolated dog heart
    • Herman EH, Mhatare RM, Lee IP. Prevention of cardiotoxic effects of adriamycin and daunomycin in the isolated dog heart. Proc Soc Exp Biol Med 1972; 140: 234-49
    • (1972) Proc Soc Exp Biol Med , vol.140 , pp. 234-249
    • Herman, E.H.1    Mhatare, R.M.2    Lee, I.P.3
  • 180
    • 0025981636 scopus 로고
    • The enzymatic hydrolysis-activation of the adriamycin cardiomycin cardioprotective agent (+)-1,2-bis (3,5-dioxopiperazinyl-1-yl) propane
    • Hasinoff BB, Reinders FX, Clark V. The enzymatic hydrolysis-activation of the adriamycin cardiomycin cardioprotective agent (+)-1,2-bis (3,5-dioxopiperazinyl-1-yl) propane. Drug Metab Dispos 1991; 19: 74-80
    • (1991) Drug Metab Dispos , vol.19 , pp. 74-80
    • Hasinoff, B.B.1    Reinders, F.X.2    Clark, V.3
  • 181
    • 0026551924 scopus 로고
    • In vitro evidence for direct complexation of ADR-529/ICRF-187 [(+)-1,2-bis - (3,5-dioxopiperazin-1-yl) propane] onto an existing ferric-anthracycline complex
    • Sobol MM, Amiet RG, Green MD. In vitro evidence for direct complexation of ADR-529/ICRF-187 [(+)-1,2-bis - (3,5-dioxopiperazin-1-yl) propane] onto an existing ferric-anthracycline complex. Mol Pharmacol 1992; 41: 8-17
    • (1992) Mol Pharmacol , vol.41 , pp. 8-17
    • Sobol, M.M.1    Amiet, R.G.2    Green, M.D.3
  • 182
    • 0023693833 scopus 로고
    • Protective effect of the bispiperazinedione ICRF-187 against doxorubicin induced cardiotoxicity in women with advanced breast cancer
    • Speyer JL, Green MD, Kramer E, etl al. Protective effect of the bispiperazinedione ICRF-187 against doxorubicin induced cardiotoxicity in women with advanced breast cancer. N Engl J Med 1988; 319 (12): 745-52
    • (1988) N Engl J Med , vol.319 , Issue.12 , pp. 745-752
    • Speyer, J.L.1    Green, M.D.2    Kramer, E.3
  • 183
    • 0344309483 scopus 로고
    • ICRF-187 reduces doxorubicin-induced cardiotoxicity with no impact on response to chemotherapy
    • Wexler LH, Berg S, Andrich M, et al. ICRF-187 reduces doxorubicin-induced cardiotoxicity with no impact on response to chemotherapy [abstract]. Proc Am Soc Clin Oncol 1993; 12: 418
    • (1993) Proc Am Soc Clin Oncol , vol.12 , pp. 418
    • Wexler, L.H.1    Berg, S.2    Andrich, M.3
  • 185
    • 0013593629 scopus 로고
    • Prevention of adriamycin cardiomyopathy with dexrazoxane (ADR-529, ICRF-87)
    • York RM, Rosenfeld CS, Weisberg SR, et al. Prevention of adriamycin cardiomyopathy with dexrazoxane (ADR-529, ICRF-87) [abstract]. Proc Am Soc Clin Oncol 1992; 11: 62
    • (1992) Proc Am Soc Clin Oncol , vol.11 , pp. 62
    • York, R.M.1    Rosenfeld, C.S.2    Weisberg, S.R.3
  • 187
    • 0342909138 scopus 로고
    • Cardioxone (ICRF-187) protects against epirubicin (Epi) induced cardiomyopathy in advanced breast cancer (ABC) patients: A phase III study
    • Michelotti A, Venturini M, Conte PS, et al. Cardioxone (ICRF-187) protects against epirubicin (Epi) induced cardiomyopathy in advanced breast cancer (ABC) patients: a phase III study [abstract]. Proc Am Soc Clin Oncol 1995; 14: 98
    • (1995) Proc Am Soc Clin Oncol , vol.14 , pp. 98
    • Michelotti, A.1    Venturini, M.2    Conte, P.S.3
  • 188
    • 0019465060 scopus 로고
    • Phase I evaluation of ICRF-187 in patients with advanced malignancy
    • Liesmann J, Belt R, Haas C, et al. Phase I evaluation of ICRF-187 in patients with advanced malignancy. Cancer 1981; 47: 1959-62
    • (1981) Cancer , vol.47 , pp. 1959-1962
    • Liesmann, J.1    Belt, R.2    Haas, C.3
  • 189
    • 9044233260 scopus 로고    scopus 로고
    • Randomised trial of the Cardioprotective agent ICRF-187 in pediatric sarcoma patients treated with doxorubicin
    • Wexler LH, Andrich MP, Venzon D. Randomised trial of the Cardioprotective agent ICRF-187 in pediatric sarcoma patients treated with doxorubicin. J Clin Oncol 1996; 14 (2): 362-72
    • (1996) J Clin Oncol , vol.14 , Issue.2 , pp. 362-372
    • Wexler, L.H.1    Andrich, M.P.2    Venzon, D.3
  • 190
    • 0021029382 scopus 로고
    • Prevention of chronic doxorubicin cardiotoxicity in beagles by liposomal encapsulation
    • Herman EH, Rahman A, Ferrans VJ, et al. Prevention of chronic doxorubicin cardiotoxicity in beagles by liposomal encapsulation. Cancer Res 1983; 43: 5427-32
    • (1983) Cancer Res , vol.43 , pp. 5427-5432
    • Herman, E.H.1    Rahman, A.2    Ferrans, V.J.3
  • 191
    • 0003296412 scopus 로고    scopus 로고
    • Phase II dose find ing trial of Dox-SL (Stealth Liposomal Doxorubicin HCL) in the treatment of advanced breast cancer
    • Ranson M, O'Byrne K, Carmichael J, et al. Phase II dose find ing trial of Dox-SL (Stealth Liposomal Doxorubicin HCL) in the treatment of advanced breast cancer [abstract]. Proc Am Soc Clin Oncol 1996; 15: 161
    • (1996) Proc Am Soc Clin Oncol , vol.15 , pp. 161
    • Ranson, M.1    O'Byrne, K.2    Carmichael, J.3
  • 192
    • 0345070488 scopus 로고
    • Decreased cardiac toxicity by TLC D-9 (liposomal doxorubicin) in the treatment of metastatic breast cancer (MBC)
    • Fonseca GA, Valero A, Buzdar R. Decreased cardiac toxicity by TLC D-9 (liposomal doxorubicin) in the treatment of metastatic breast cancer (MBC) [abstract]. Proc Am Soc Clin Oncol 1995; 14: 99
    • (1995) Proc Am Soc Clin Oncol , vol.14 , pp. 99
    • Fonseca, G.A.1    Valero, A.2    Buzdar, R.3
  • 193
    • 0020512136 scopus 로고
    • 4′ Epi-doxorubicin, a new analogue of doxorubicin: A preliminary overview of pre-clinical and clinical data
    • Ganzina F. 4′ Epi-doxorubicin, a new analogue of doxorubicin: a preliminary overview of pre-clinical and clinical data. Cancer Treat Symp 1983; 10: 1-22
    • (1983) Cancer Treat Symp , vol.10 , pp. 1-22
    • Ganzina, F.1
  • 194
    • 0021833736 scopus 로고
    • A prospective randomised comparison of epirubicin and doxorubicin in patients with advanced breast cancer
    • Jain K K, Casper ES, Geller NL, et al. A prospective randomised comparison of epirubicin and doxorubicin in patients with advanced breast cancer. J Clin Oncol 1985; 3: 818-26
    • (1985) J Clin Oncol , vol.3 , pp. 818-826
    • Jain, K.K.1    Casper, E.S.2    Geller, N.L.3
  • 195
    • 0025155529 scopus 로고
    • Epirubicin Cardiotoxicity: Study of 135 patients with advanced breast cancer
    • Nielsen D, Jensen P, Dobernowski O, et al. Epirubicin Cardiotoxicity: study of 135 patients with advanced breast cancer. J Clin Oncol 1990; 8: 1806-10
    • (1990) J Clin Oncol , vol.8 , pp. 1806-1810
    • Nielsen, D.1    Jensen, P.2    Dobernowski, O.3
  • 196
    • 0026341564 scopus 로고
    • New anthracycline derivatives: What for?
    • Mross K. New anthracycline derivatives: what for? Eur J Cancer 1991; 27: 1542-4
    • (1991) Eur J Cancer , vol.27 , pp. 1542-1544
    • Mross, K.1
  • 197
    • 0025365946 scopus 로고
    • New cytotoxic drugs in the treatment of breast cancer
    • Mourisden HT. New cytotoxic drugs in the treatment of breast cancer. Acta Oncol 1990; 29: 343-7
    • (1990) Acta Oncol , vol.29 , pp. 343-347
    • Mourisden, H.T.1
  • 198
    • 0027159174 scopus 로고
    • Epirubicin: A review of its pharmacodynamic and pharmacokinetics properties and therapeutic use in cancer chemotherapy
    • Plosker GL, Faulds D. Epirubicin: a review of its pharmacodynamic and pharmacokinetics properties and therapeutic use in cancer chemotherapy. Drugs 1993; 45 (5): 788-856
    • (1993) Drugs , vol.45 , Issue.5 , pp. 788-856
    • Plosker, G.L.1    Faulds, D.2
  • 199
    • 0007863888 scopus 로고
    • Anthracycline analogues and carriers
    • Muggia FM, Green MD, Speyer JL, editors. Baltimore, Maryland: The Johns Hopkins University Press
    • McVie JG. Anthracycline analogues and carriers. In: Muggia FM, Green MD, Speyer JL, editors. Cancer treatment and the heart. 1st ed. Baltimore, Maryland: The Johns Hopkins University Press, 1992: 217-45
    • (1992) Cancer Treatment and the Heart. 1st Ed. , pp. 217-245
    • McVie, J.G.1
  • 200
    • 0024245881 scopus 로고
    • A randomised multicenter trial comparing mitoxantrone, cyclophosphamide and fluorouracil with doxorubicin, cyclophosphamide and fluorouracil in the therapy of metastatic breast carcinoma
    • Bennett JM, Muss HS, Doroshow JH, et al. A randomised multicenter trial comparing mitoxantrone, cyclophosphamide and fluorouracil with doxorubicin, cyclophosphamide and fluorouracil in the therapy of metastatic breast carcinoma. J Clin Oncol 1988; 6: 1611-20
    • (1988) J Clin Oncol , vol.6 , pp. 1611-1620
    • Bennett, J.M.1    Muss, H.S.2    Doroshow, J.H.3
  • 201
    • 0021738692 scopus 로고
    • Mitoxantrone cardiotoxicity: Results from the South-Eastern cancer study group
    • Gams RA, Wesler MJ. Mitoxantrone cardiotoxicity: results from the South-Eastern cancer study group. Cancer Treat Symp 1984; 3: 31-7
    • (1984) Cancer Treat Symp , vol.3 , pp. 31-37
    • Gams, R.A.1    Wesler, M.J.2
  • 202
    • 0021883906 scopus 로고
    • Mitoxantrone: An overview of safety and toxicity
    • Posner LE, Dukart G, Goldberg J, et al. Mitoxantrone: an overview of safety and toxicity. Invest New Drugs 1985; 3: 123-32
    • (1985) Invest New Drugs , vol.3 , pp. 123-132
    • Posner, L.E.1    Dukart, G.2    Goldberg, J.3
  • 203
    • 0024520987 scopus 로고
    • Randomised clinical trial comparing mitoxantrone with doxorubicin in previously treated patients with metastatic breast cancer
    • Henderson IC, Allegro JC, Woodcock T. Randomised clinical trial comparing mitoxantrone with doxorubicin in previously treated patients with metastatic breast cancer. J Clin Oncol 1989; 7 (5): 560-71
    • (1989) J Clin Oncol , vol.7 , Issue.5 , pp. 560-571
    • Henderson, I.C.1    Allegro, J.C.2    Woodcock, T.3
  • 204
    • 0026552469 scopus 로고
    • Results of a randomised study of previously untreated intermediate and high grade lymphomas using CHOP versus CNOP
    • Pavloski M, Santorelli MT, Erazo A, et al. Results of a randomised study of previously untreated intermediate and high grade lymphomas using CHOP versus CNOP. Ann Oncol 1992; 3: 205-9
    • (1992) Ann Oncol , vol.3 , pp. 205-209
    • Pavloski, M.1    Santorelli, M.T.2    Erazo, A.3
  • 205
    • 0024383072 scopus 로고
    • Phase I study of KRN 8602 (MX2), a new morpholino anthracycline
    • Tabata T, Ogawa M, Horikoshi N, et al. Phase I study of KRN 8602 (MX2), a new morpholino anthracycline. Jpn J Cancer Chemother 1989; 16 (7): 2361-6
    • (1989) Jpn J Cancer Chemother , vol.16 , Issue.7 , pp. 2361-2366
    • Tabata, T.1    Ogawa, M.2    Horikoshi, N.3
  • 206
    • 0022560064 scopus 로고
    • Uptake and retention of morphinyl anthracyclines by adriamycin sensitive and resistant P388 cells
    • Streeter DG, Johl JS, Gordon GR. Uptake and retention of morphinyl anthracyclines by adriamycin sensitive and resistant P388 cells. Cancer Chemother Pharmacol 1992; 16: 247-52
    • (1992) Cancer Chemother Pharmacol , vol.16 , pp. 247-252
    • Streeter, D.G.1    Johl, J.S.2    Gordon, G.R.3
  • 207
    • 1842710666 scopus 로고    scopus 로고
    • MX2 (KRN 8602): An active new agent in patients with high grade malignant glioma
    • Clarke K, Green MD, Mitchell P, et al. MX2 (KRN 8602): an active new agent in patients with high grade malignant glioma [abstract]. Proc Am Soc Clin Oncol 1996; 15: 29
    • (1996) Proc Am Soc Clin Oncol , vol.15 , pp. 29
    • Clarke, K.1    Green, M.D.2    Mitchell, P.3
  • 208
    • 0025040921 scopus 로고
    • Morpholinyl anthracyclines: Option for reversal of anthracycline resistance
    • de Vries EGE, Zijlstra JG. Morpholinyl anthracyclines: option for reversal of anthracycline resistance. Eur J Cancer 1990; 26 (6): 659-60
    • (1990) Eur J Cancer , vol.26 , Issue.6 , pp. 659-660
    • De Vries, E.G.E.1    Zijlstra, J.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.