Molecular analysis of transient cytogenetic relapse after allogeneic bone marrow transplantation for chronic myeloid leukaemia

Bone Marrow Transplantation

Volumn 18, Issue 6, 1996, Pages 1147-1152

  Lin, F ^a   Kirkland, M A ^a   Van Rhee, F ^a   Chase, A ^a   Coulthard, S ^a   Bungey, J ^a   Goldman, J M ^a   Cross, N C P ^a,b  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

BMT; CML; PCR; Relapse

Indexed keywords

ALEMTUZUMAB; BCR ABL PROTEIN; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; MESSENGER RNA; METHOTREXATE;

ADULT; ALLOGENIC BONE MARROW TRANSPLANTATION; ARTICLE; B LYMPHOCYTE; CHRONIC MYELOID LEUKEMIA; CLINICAL PROTOCOL; CYTOGENETICS; EARLY DIAGNOSIS; FEMALE; HEMATOLOGY; HUMAN; HUMAN CELL; IMMUNOSUPPRESSIVE TREATMENT; LEUKEMIA REMISSION; LYMPHOID CELL; MAJOR CLINICAL STUDY; MALE; MINIMAL RESIDUAL DISEASE; PHILADELPHIA 1 CHROMOSOME; PRIORITY JOURNAL; RELAPSE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK; RNA TRANSCRIPTION; T LYMPHOCYTE;

ADULT; BONE MARROW TRANSPLANTATION; FEMALE; FOLLOW-UP STUDIES; FUSION PROTEINS, BCR-ABL; HUMANS; LEUKEMIA, MYELOID, PHILADELPHIA-POSITIVE; MALE; NEOPLASM CIRCULATING CELLS; NEOPLASM, RESIDUAL; POLYMERASE CHAIN REACTION; RECURRENCE; REMISSION INDUCTION; TIME FACTORS; TRANSPLANTATION CONDITIONING; TRANSPLANTATION, HOMOLOGOUS; TUMOR MARKERS, BIOLOGICAL; TUMOR STEM CELL ASSAY; TUMOR STEM CELLS;

EID: 0030444375     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Kolb HJ, Mittermuller S, Clemm Ch et al. Donor leukocyte transfusions for treatment of recurrent chronic myelogenous leukemia in marrow transplant patients. Blood 1990; 76: 2642-2650.
2. Porter DL, Roth MS, McGarigle C et al. Induction of graftversus-host disease as immunotherapy for chronic myeloid leukemia relapsed after allogeneic bone marrow transplantation. New Engl J Med 1993; 330; 100-106.
3. van Rhee F, Lin F, Cullis JO et al. Relapse of chronic myeloid leukemia after allogeneic bone marrow transplant: the case for giving donor leukocyte transfusions before the onset of hematologic relapse. Blood 1994; 83: 3377-3383.
4. Kolb HJ, Schattenberg A, Goldman JM et al. Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients. Blood 1995; 86: 2041-2050.
5. Sawyers CL, Timson L, Kawasaki ES et al. Molecular relapse in chronic myelogenous leukemia patients after bone marrow transplantation detected by polymerase chain reaction. Proc Natl Acad Sci USA 1990; 87: 563-567.
6. Delage R, Soiffer RJ, Dear K et al. Clinical significance of bcr-ab1 gene rearrangement detected by polymerase chain reaction after allogeneic bone marrow transplantation in chronic myelogenous leukemia. Blood 1991; 78: 2759-2767.
7. Roth MS, Antin JH, Ash R et al. Prognostic significance of Philadelphia chromosome-positive cells detected by the polymerase chain reaction after allogeneic bone marrow transplant for chronic myelogenous leukemia. Blood 1992; 79: 276-282.
8. Cross NCP, Hughes TP, Feng L et al. Minimal residual disease after allogeneic bone marrow transplantation for chronic myeloid leukaemia in first chronic phase, correlations with acute graft-versus-host disease and relapse. Br J Haematol 1993; 84: 67-74.
9. Miyamura K, Tahara T, Tanimoto M et al. Long persistent bcr-abl positive transcript detected by polymerase chain reaction after marrow transplant for chronic myelogenous leukemia without clinical relapse: a study of 64 patients. Blood 1993; 81: 1089-1093.
10. Miyamura K, Barrett AJ, Kodera Y et al. Minimal residual disease after bone marrow transplantation for chronic myelogenous leukemia and implications for graft-versus-leukemia effect: a review of recent results. Bone Marrow Transplant 1994; 14: 201-209.
11. Cross NCP, Lin F, Chase A et al. Competitive polymerase chain reaction to estimate the number of BCR-ABL transcripts in chronic myeloid leukemia patients after bone marrow transplantation. Blood 1993; 82: 1929-1936.
12. Lion T, Henn T, Gaiger A et al. Early detection of relapse after bone marrow transplantation in patients with chronic myelogenous leukaemia. Lancet 1993; 341: 275-276.
13. Lin F, van Rhee F, Goldman JM et al. Kinetics of increasing BCR-ABL transcript numbers in chronic myeloid leukemia patients who relapse after bone marrow transplantation, Blood 1996; 87: 4473-4478.
14. Apperley JF, Rassool F, Parreira A et al. Philadelphia-positive metaphases in the marrow after bone marrow transplantation for chronic granulocytic leukemia. Am J Hematol 1986; 22: 199-204.
15. Arthur CK, Apperley JF, Guo AP et al. Cytogenetic events after bone marrow transplantation for chronic myeloid leukemia in chronic phase. Blood 1988; 71: 1179-1186.
16. Zaccaria A, Rosti G, Sessarego M et al. Relapse after allogeneic bone marrow transplantation for Philadelphia chromosome positive chronic myeloid leukemia: cytogenetic analysis of 24 patients. Bone Marrow Transplant 1988; 3: 413-423.
17. Arcese W, Goldman JM, D'Arcangelo E et al. Outcome for patients who relapse after allogeneic bone marrow transplantation for chronic myeloid leukemia. Chronic Leukemia Working Party. European Bone Marrow Transplantation Group. Blood 1993; 82: 3211-3219.
18. Marks DI, Cullis JO, Ward KN et al. Allogeneic bone marrow transplantation for chronic myeloid leukemia using sibling and volunteer unrelated donors. Ann Intern Med 1993; 119: 207-216.
19. van Rhee F, Marks DI, Lin F et al. Quantification of residual disease in Philadelphia-positive acute lymphoblastic leukemia - comparison of blood and bone marrow. Leukemia 1995; 9: 329-335.
20. Kirkland MA, Spencer A, Davidson RJ et al. Quantitation of mafosfamide-resistant pre-colony-forming units in allogeneic bone marrow transplantation: relationship with rate of engraftment and evidence for long-lasting reduction in stem cell numbers. Blood 1996; 87: 3963-3969.
21. Gordon MY. Plastic-adherent cells in human bone marrow generate long-term hematopoiesis in vitro. Leukemia 1994; 8: 865-870.
22. Lin F, Chase A, Bungey J et al. Correlation between the proportion of Philadelphia chromosome positive metaphases and levels of BCR-ABL mRNA in chronic myeloid leukaemia. Genes Chromosom Cancer 1995; 13: 110-114.
23. Horowitz MM, Gale RP, Sondel PM et al Graft-versus-leukemia reactions after bone marrow transplantation. Blood 1990; 75: 555-562.