The unique role of interferon-γ in the regulation of MHC expression on arterial endothelium

Transplantation

Volumn 62, Issue 12, 1996, Pages 1889-1894

  Goes, Nelson ^a   Urmson, Joan ^a   Hobart, Michael ^a   Halloran, Philip F ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANIMAL CELL; ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; CONFERENCE PAPER; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; ORGAN TRANSPLANTATION; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM;

ANIMALS; ANTIGENS, LY; ARTERIES; BIOLOGICAL MARKERS; ENDOTHELIUM, LYMPHATIC; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION; INTERCELLULAR ADHESION MOLECULE-1; INTERFERON TYPE II; INTERFERON-GAMMA, RECOMBINANT; MAJOR HISTOCOMPATIBILITY COMPLEX; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT;

EID: 0030443954     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199612270-00036     Document Type: Conference Paper

References (33)

1. Germain RN. MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation. Cell 1994; 76: 287.
2. Fleming KA, McMichael A, Morton JA, Woods J, McGee JO. Distribution of HLA class I antigens in normal human tissue and in mammary cancer. J Clin Pathol 1981; 34: 779.
3. Gervais AG. Detection of mouse histocompatibility antigens by immunofluorescence. Transplantation 1968; 6: 261.
4. Saunders DA, Beals TF, Schultz JS. Qualitative and quantitative evaluation of indirect immunofluorescent H-2 stain on tissue sections. Tissue Antigens 1979; 14: 73.
5. Mantovani A, Bussolino F, Dejana E. Cytokine regulation of endothelial cell function. FASEB J 1992; 6: 2591.
6. Farrar MA, Schreiber RD. The molecular cell biology of interferon-γ and its receptor. Annu Rev Immunol 1993; 11: 571.
7. Dalton DK, Pitts-Meek S, Keshav S, Figari IS, Bradley A, Stewart TA. Multiple defects of immune cell function in mice with disrupted interferon-γ genes. Science 1993; 259: 1739.
8. Huang S, Hendricks W, Althage A, et al. Immune response in mice that lack the interferon-γ receptor. Science 1993; 259: 1742.
9. Cooper AM, Dalton DK, Stewart TA, Griffin JP, Russell DG, Orme IM. Disseminated tuberculosis in interferon γ gene-disrupted mice. J Exp Med 1993; 178: 2243.
10. Goes N, Sims T, Urmson J, Vincent D, Ramassar V, Halloran PF. Disturbed MHC regulation in the interferon-γ knockout mouse. J Immunol 1995; 155: 4559.
11. Jephthah-Ochola J, Urmson J, Farkas S, Halloran PF. Regulation of MHC in vivo: bacterial lipopolysaccharide induces class I and II MHC products in mouse tissues by a T cell independent, cyclosporine sensitive mechanism. J Immunol 1988; 141: 792.
12. Palfree RGE, Dumont FJ, Hammerling U. Ly-6A.2 and Ly-6E.1 molecules are antithetical and identical to MALA-1. Immunogenetics 1986; 23: 197.
13. Cockfield SM, Ramassar V, Urmson J, Halloran PF. Multiple low dose streptozotocin induces systemic MHC expression in mice by triggering T cells to release IFN-γ. J Immunol 1989; 142: 1120.
14. Blake PG, Madrenas J, Halloran PF. Ly-6 in kidney is widely expressed on tubular epithelium and vascular endothelium and is upregulated by interferon gamma. J Am Soc Nephrol 1993; 4: 1140.
15. Hou J, Baichwal V, Cao Z. Regulatory elements and transcription factors controlling basal and cytokine-induced expression of the gene encoding intercellular adhesion molecule 1. Proc Natl Acad Sci USA 1994; 91: 11641.
16. Halloran PF, Urmson J, Farkas S, van der Meide P, Autenried P. Regulation of MHC expression in vivo: IFN-α/β inducers and recombinant IFN-α modulate MHC antigen expression in mouse tissues. J Immunol 1989; 142: 4241.
17. Halloran PF, Jephthah-Ochola J, Urmson J, Farkas S. Systemic immunologic stimuli increase class I and II antigen expression in mouse kidney. J Immunol 1985; 135: 1053.
18. Cockfield SM, Ramassar V, Noujaim J, van der Meide PH, Halloran PF. Regulation of IFN-γ expression in vivo: IFN-γ up-regulates expression of its mRNA in normal and lipopolysaccharide-stimulated mice. J Immunol 1993; 150: 717.
19. Halloran PF, Autenried P, Ramassar V, Urmson J, Cockfield S. Local T cell responses induce widespread MHC expression. Evidence that IFN-γ induces its own expression in remote sites. J Immunol 1992; 148: 3837.
20. de la Salle H, Hanau D, Fricker D, et al. Homozygous human TAP peptide transporter mutation in HLA class I deficiency. Science 1994; 265: 237.
21. Kelly A, Powis SH, Kerr LA, et al. Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex. Nature 1992; 355: 641.
22. Powis SJ, Townsend ARM, Deverson EV, Bastin J, Butcher GW, Howard JC. Restoration of antigen presentation to the mutant cell line RMA-S by an MHC-linked transporter. Nature 1991; 354: 528.
23. Epperson DE, Arnold D, Spies T, Cresswell P, Pober JS, Johnson DR. Cytokines increase transporter in antigen processing-1 expression more rapidly than HLA class I expression in endothelial cells. J Immunol 1992; 149: 3297.
24. Min W, Pober JS, Johnson DR. Kinetically coordinated induction of TAP1 and HLA class I by IFN-gamma. J Immunol 1996; 156: 3174.
25. Collins T, Korman AJ, Wake CT, et al. Immune interferon activates multiple class II histocompatibility complex genes and the associated invariant chain gene in human endothelial cells and dermal fibroblasts. Proc Natl Acad Sci USA 1984; 81: 4917.
26. Ihle JN. STATs: signal transducers and activators of transcription. Cell 1996; 84: 331.
27. Dumont FJ, Coker LZ. Interferon α/β enhances the expression of Ly-6 antigens on T cells in vivo and in vitro. Eur J Immunol 1986; 16: 735.
28. Dumont FJ, Dijkmans R, Palfree RGE, Boldtz RD, Coker L. Selective up-regulation by interferon-γ of surface molecules of the Ly-6 complex in resting T cells: the Ly-6A/E and TAP antigens are preferentially enhanced. Eur J Immunol 1987; 17: 1183.
29. Hart DNJ, Fuggle SV, Williams KA, Fabre JW, Ting A, Morris PJ. Localization of HLA-ABC and DR antigens in human kidney. Transplantation 1981; 31: 428.
30. Daar AS, Fuggle SV, Fabre JW, Ting A, Morris PJ. The detailed distribution of MHC class II antigens in normal human kidney. Transplantation 1984; 38: 293.
31. Daar AS, Fuggle SV, Fabre JW, Ting A, Morris PJ. The detailed distribution of HLA-A,B,C antigens in normal human kidney. Transplantation 1984; 38: 287.
32. de Waal RMW, Bogman MJJ, Maass CN, Cornelissen LMH, Tax WJM, Koene RAP. Variable expression of Ia antigens on the vascular endothelium of mouse skin allografts. Nature 1983; 303: 426.
33. Skoskiewicz M, Colvin RB, Schneeberger EE, Russell PS. Widespread and selective induction of major histocompatibility complex-determined antigens in vivo by γ interferon. J Exp Med 1985; 162: 1645.