Recent developments in the genetics of bipolar disorder

Cold Spring Harbor Symposia on Quantitative Biology

Volumn 61, Issue , 1996, Pages 783-789

  Depaulo Jr , J R ^a   Mcmahon, F J ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; CHROMOSOME 18; CHROMOSOME 21; COMORBIDITY; CONFERENCE PAPER; HUMAN; MANIC DEPRESSIVE PSYCHOSIS; ONSET AGE; PHENOTYPE; PRIORITY JOURNAL; SCHIZOPHRENIA; ARTICLE; BIPOLAR DISORDER; GENETICS; MAJOR AFFECTIVE DISORDER; PHENOTYPIC VARIATION;

EID: 0030441741     PISSN: 00917451     EISSN: None     Source Type: Book Series    
DOI: 10.1101/sqb.1996.061.01.077     Document Type: Conference Paper

References (64)

1. Akiskal, H.S. 1994. The temperamental borders of affective disorders. Acta Psychiatr. Scand. Suppl. 379: 32.
2. Andreasen, N.C., W.M. Grove, R.W. Shapiro, M.B. Keller, R.M.A. Hirschfeld, and P. McDonald-Scott. 1981. Reliability of lifetime diagnosis: A multicenter collaborative perspective. Arch. Gen. Psychiatry 38: 400.
3. Ayuso-Gutierrez, J.L. and J.A. Ramos-Brieva. 1982. The course of manic-depressive illness: A comparative study of bipolar I and bipolar II patients. J. Affective Disord. 4: 9.
4. Baron, M. 1993. Manic-depression linkage to factor IX reconsidered (Letter; Comment). Ann. Genet. 36: 187.
5. _. 1994. Novel strategies in molecular genetics of mental illness (Editorial). Biol. Psychiatry 35: 757.
6. Baron, M., N. Risen, R. Hamburger, B. Mandel, S. Kushner, M. Newman, D. Drumer, and R.H. Belmaker. 1987. Genetic linkage between X-chromosome markers and bipolar affective illness. Nature 326: 289.
7. Baron, M., N.F. Freimer, N. Risch, B. Lerer, J.R. Alexander, R.E. Straub, S. Asokan, K. Das, A. Peterson, J. Amos, J. Endicott, J. Ott, and T.C. Gilliam. 1993. Diminished support for linkage between manic depressive illness and X-chromosome markers in three Israeli pedigrees. Nat. Genet. 3: 49.
8. Baron, M., J. Endicott, B. Lerer, J.E. Loth, J.R. Alexander, R. Simon, L. Sharpe, M. Gibbon, D. Hasin, B. Lilliston, S. Schacht, R. Blumenthal, J. Alexander, A. Verter, N. Tubi, R.R. Fieve, T.C. Gillian, T. Lehner, and J. Ott. 1994. A pedigree series for mapping disease genes in bipolar affective disorder sampling, assessment, and analytic considerations. Psychiatr. Genet. 4: 43.
9. Berrettini, W.H., T.N. Ferraro, L.R. Goldin, D.E. Weeks, S. Detera-Wadleigh, J.I. Nurnberger, Jr., and E.S. Gershon. 1994. Chromosome 18 DNA markers and manic-depressive illness: Evidence for a susceptibility gene. Proc. Natl. Acad. Sci. 91: 5918.
10. Berrettini, W.H., T.N. Ferraro, L.R. Goldin, S.D. Detera-Wadleigh, H. Choi, D. Muniec, J.G. Guroff, D.M. Kazuba, J.I. Nurnberger, Jr., W.-T. Hsieh, M.R. Hoehe, and E.S. Gershon. 1997. A linkage study of bipolar illness. Arch. Gen. Psychiatry 54: 27.
11. Blacker, D. and M.T. Tsuang. 1993. Unipolar relatives in bipolar pedigrees: Are they bipolar? Psychiatr. Genet. 3: 5.
12. Blackwood, D.H.R., L. He, S.W. Morris, A. McLean, C. Whitton, M. Thompson, M.T. Walker, K. Woodburn, C.M. Sharp, A.F. Wright, Y. Shibasaki, D.M. St. Clair, D.J. Porteous, and W.J. Muir. 1996. A locus for bipolar affective disorder on chromosome 4p. Nat. Genet. 12: 427.
13. Calzolari, E., V. Aiello, P. Palazzi, A. Sensi, S. Calzolari, D. Orrico, H. Holler, C. Marzi, S. Belli, F. Bernardi, and P. Patracchini. 1996. Psychiatric disorder in a familial 15-18 translocation and sublocalization of myelin basic protein to 18Q22.3. Am. J. Med. Genet. 67: 154.
14. Coon, H., J. Jensen, M. Hoff, J. Holik, R. Plaetke, F. Reimherr, P. Wender, M. Leppert, and W. Byerley. 1993. A genome-wide search for genes predisposing to manic depression, assuming autosomal dominant inheritance. Am. J. Hum. Genet 52: 1234.
15. Copeman, J.B., F. Cucca, C.M. Heame, R.J. Cornall, P.W. Reed, K.S. Rönningen, D.E. Undlien, L. Nistico, R. Buzzetti, R. Tosi, F. Pociot, J. Nerup, F. Cornélis, A.H. Barnett, S.C. Bain, and J.A. Todd. 1995. Linkage disequilibrium mapping of a type 1 diabetes susceptibility gene (IDDM7) to chromosome 2q31-q33. Nat. Genet. 9: 80.
16. DeBruyn, A., D. Souery, K. Mendelbaum, J. Mendlewicz, and C. Vanbroeckhoven. 1996. Linkage analysis of families with bipolar illness and chromosome 18 markers. Biol. Psychiatry 39: 679.
17. Detera-Wadleigh, S.D., J.A. Badner, L.R. Goldin, W.H. Berrettini, A.R. Sanders, D.Y. Rollins, G. Turner, T. Moses, H. Haerian, D. Muniec, J.I. Nurnberger, Jr., and E.S. Gershon. 1996. Affected-sib-pair analyses reveal support of prior evidence for a susceptibility locus for bipolar disorder, on 21q. Am. J. Hum. Genet. 58: 1279.
18. Dunner, D.L. and L.K. Tay. 1993. Diagnostic reliability of the history of hypomania in bipolar II patients and patients with major depression. Compr. Psychiatry 34: 303.
19. Egeland, J.A., D.S. Gerhard, D.L. Pauls, J.N. Sussex, K.K. Kidd, C.R. Allen, A.M. Hostetter, and D.E. Housman. 1987. Bipolar affective disorders linked to DNA markers on chromosome 11. Nature 325: 783.
20. Endicott, J., J. Nee, N. Andreason, P. Clayton, M. Keller, and W. Coryell. 1985. Bipolar II: Combine or keep separate? J. Affective Disord. 8: 17.
21. Freimer, N.B., V.I. Reus, M.A. Escamilla, L.A. McInnes, M. Spesny, P. Leon, S.K. Service, L.B. Smith, S. Silva, E. Rojas, A. Gallegos, L. Meza, E. Fournier, S. Baharloo, K. Blankenship, D.J. Tyler, S. Batki, S. Vinogradov, J. Weissenbach, S.H. Barondes, and L.A. Sandkuijl. 1996. Genetic mapping using haplotype, association and linkage methods suggests a locus for severe bipolar disorder (BPI) at 18q22-q23. Nat. Genet. 12: 436.
22. Gershon, E.S., J.H. Hamovit, J.J. Guroff, and J.I. Nurnberger. 1987. Birth-cohort changes in manic and depressive disorders in relatives of bipolar and schizoaffactive patients. Arch. Gen. Psychiatry 44: 314.
23. Gershon, E.S., J.A. Badner, S.D. Detera-Wadleigh, T.N. Ferraro, and W.H. Berrettini. 1996. Maternal inheritance and chromosome 18 allele sharing in unilineal bipolar illness pedigrees. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 67: 202.
24. Gershon, E.S., J. Hamovit, J.J. Guroff, J.I. Nurnberger, L.R. Goldin, and W.E. Bunney. 1982. A family study of schizoaffective, bipolar I, bipolar II, unipolar and normal control probands. Arch. Gen. Psychiatry 39: 1157.
25. Ginns, E.I., J. Ott, J.A. Egeland, C.R. Allen, C.S.J. Fann, D.L. Pauls, J. Weissenbach, J.P. Carulli, K.M. Falls, T.P. Keith, and S.M. Paul. 1996. A genome-wide search for chromosomal loci linked the bipolar affective disorder in the Old Order Amish. Nat. Genet. 12: 431.
26. Gurling, H.M.D. and T. Sharma. 1994. Genetic linkage analysis and clinical approaches to the resolution of heterogeneity in the schizophrenias. In Genetic approaches to mental disorders (ed. E.S. Gershon and C.R. Cloninger), p. 231. American Psychiatric Press, Washington, D.C.
27. Gurling, H., C. Smyth, G. Kalsi, E. Moloney, L. Rifkin, J. O'Neill, P. Murphy, D. Curtis, H. Petursson, and J. Brynjolfsson. 1995. Linkage findings in bipolar disorder (Letter). Nat. Genet. 10: 8.
28. Kelsoe, J.R., E.I. Ginns, J.A. Egeland, D.S. Gerhard, A.M. Goldstein, S.J. Bale, D.L. Pauls, R.T. Long, K.K. Kidd, and G. Conte. 1989. Re-evaluation of the linkage relationship between chromosome 11p loci and the gene for bipolar affective disorder in the Old Order Amish. Nature 342: 238.
29. Klerman, G.L. and M.M. Weissman. 1989. Increasing rates of depression (Comments; Review). J. Am. Med. Assoc. 261: 2229.
30. Kraepelin, E. 1921. Manic-depressive insanity and paranoia. E. & S. Livingstone, Edinburgh, Scotland.
31. Lander, E. and L. Kruglyak. 1996. Genetic dissection of complex traits (reply). Nat. Genet. 12:357.
32. MacKinnon, D.F., F.J. McMahon, S.G. Simpson, M.G. McInnis, and J.R. DePaulo. 1997. Panic disorder with familial bipolar disorder. Biol. Psychiatry (in press).
33. McInnis, M.G., F.J. McMahon, G. Chase, S.G. Simpson, C.A. Ross, and J.R. DePaulo, Jr. 1993. Anticipation in bipolar affective disorder. Am. J. Hum. Genet. 53: 385.
34. McMahon, F.J. and J.R. DePaulo. 1996. Genetics and age at onset. In Mood disorders across the life span (ed. K.I. Schulman et al.), p. 35. Wiley-Liss, New York.
35. McMahon, F.J., O.C. Stine, D.A. Meyers, S.G. Simpson, and J.R. DePaulo. 1995. Patterns of maternal transmission in bipolar affective disorder. Am. J. Hum. Genet. 56: 1277.
36. McMahon, F.J., J. Xu, C. Stine, S.G. Simpson, and J.R. DePaulo, Jr. 1996. Clinical features of bipolar disorder linked to chromosome 18. In Abstracts from the American Psychiatric Association Meeting (NR651). American Psychiatric Association, Washington, D.C.
37. McMahon, F.J., G.A. Chase, S.G. Simpson, D.A. Meyers, O.C. Stine, S.E. Folstein, and J.R. DePaulo, Jr. 1994. Influence of clinical subtype, sex, and lineality on age at onset of major affective disorder in a family sample. Am. J. Psychiatry 151: 210.
38. Mendlewicz, J. and J.D. Rainer. 1977. Adoption study supporting genetic transmission in manic-depressive illness. Nature 268: 327.
39. Mendlewicz, J., J.L. Fleiss, and R.R. Fieve. 1972. Evidence for X-linkage in the transmission of manic-depressive illness. J. Am. Med. Assoc. 222: 1624.
40. Mendlewicz, J., P. Linkoeski, and J. Wilmotte. 1980. Linkage between glucose-phosphate dehydrogenase deficiency and manic-depressive psychosis. Br. J. Psychiatry. 137: 337.
41. Mendlewicz, J., R.R. Fieve, J.D. Rainer, and M. Cataldo. 1973. Affective disorder on paternal and maternal sides: Observations in bipolar (manic-depressive) patients with and without a family history. Br. J. Psychiatry 122: 31.
42. Nothen, M.M., S. Cochon, N. Craddock, M. Albus, W. Maier, D. Lichtermann, B. Weigelt, E. Franzek, R. Rietschel, J. Korner, R. Fimmers, and P. Propping. 1996. Linkage studies of bipolar disorder to chromosome 18 markers. Biol. Psychiatry 39: 501.
43. O'Rourke, D.H., P. McGuffin, and T. Reich. 1983. Genetic analysis of manic-depressive illness. Am. J. Phys. Anthropol. 62: 51.
44. Pekkarinen, P., J. Terwilliger, P.E. Bredbacka, J. Lonnqvist, and L. Peltonen. 1995. Evidence of a predisposing locus to bipolar disorder on Xq24-q27 in an extended Finnish pedigree. Genome Res. 5: 105.
45. Penrose, L.S. 1948. The problem of anticipation in pedigrees of dystrophia myotonica. Ann. Eugen. 14: 125.
46. Perris, C. 1971. Abnormality on paternal and maternal sides: Observations in bipolar (manic-depressive) and unipolar depressive psychoses. Br. J. Psychiatry 118: 207.
47. Reich, T., P.J. Clayton, and G. Winokur. 1969. Family history studies: V. The genetics of mania. Am. J. Psychiatry 125: 1358.
48. Riccardi, V.M. and R.A. Lewis. 1988. Penetrance of von Recklinghausen neurofibromatosis: A distinction between predecessors and descendants. Am. J. Hum. Genet. 42: 284.
49. Rice, J.P., J. Endicott, M.A. Knesevich, and N. Rochberg. 1987. The estimation of diagnostic sensitivity using stability data: An application to major depressive disorder. J. Psychiatr. Res. 21: 337.
50. Rice, J.P., P. McDonald-Scott, J. Endicott, W. Coryell, W.M. Grove, M.B. Keller, and D. Altis. 1986. The stability of diagnosis with an application to bipolar II disorder. Psychiatry Res. 19: 285.
51. Risch, N. and M. Baron. 1982. X-linkage and genetic heterogeneity in bipolar-related major affective illness: Reanalysis of linkage data. Ann. Hum. Genet. 46: 153.
52. Risch, N. and D. Botstein. 1996. A manic depressive history. Nat. Genet. 12: 351.
53. Sherrington, R., J. Brynjolfsson, H. Petursson, M. Potter, K. Dudleston, B. Barraclough, J. Wasmuth, M. Dobbs, and H. Gurling. 1988. Localization of a susceptibility locus for schizophrenia on chromosome 5. Nature 336: 154.
54. Simpson, S.G., F.J. McMahon, M.G. McInnis, D.F. MacKinnon, and J.R. DePaulo, Jr. 1996. Reliability of the bipolar II diagnosis. Psychiatr. Genet. 5: S92.
55. Simpson, S.G., S.E. Folstein, D.A. Meyers, F.J. McMahon, D.M. Busco, and J.R. DePaulo, Jr. 1993. Bipolar II: The most common phenotype? Am. J. Psychiatry 150: 901.
56. Spence, A., H. Amali, A.D. Sadovnic, R.A. Remick, J.A. Bailey-Wilson, P. Flodman, and I.M.L. Yee. 1993. A single major locus is the best explanation for bipolar family data: Results of complex segregation analyses. Psychiatr. Genet. 3: 143.
57. Stine, O.C., J. Xu, R. Koskela, F.J. McMahon, M. Gschwend, C. Friddle, C.D. Clark, M.G. McInnis, S.G. Simpson, T.S. Breschel, E. Vishio, K. Riskin, H. Feilotter, E. Chen, S. Chen, S.E. Folstein, D.A. Meyers, D. Botstein, T.G. Marr, and J.R. DePaulo. 1995. Evidence for linkage of bipolar disorder to chromosome 18 with a parent-of-origin effect. Am. J. Hum. Genet. 57: 1384.
58. Straub, R.E., T. Lehner, Y. Luo, J.E. Loth, W. Shao, L. Sharpe, J.R. Alexander, K. Das, R. Simon, R.R. Fieve, B. Lerer, J. Endicott, J. Ott, T.C. Gilliam, and M. Baron. 1994. A possible vulnerability locus for bipolar affective disorder on chromosome 21q22.3. Nat. Genet. 8: 291.
59. Taylor, M.A. and R. Abrams. 1981. Early- and late-onset bipolar illness. Arch. Gen. Psychiatry 38: 58.
60. Wicki, W. and J. Angst. 1991. The Zurich study. X. Hypomania in a 28- to 30-year-old cohort. Eur. Arch. Psychiatry Clin. Neurosci. 240: 339.
61. Winokur, G. 1979. Unipolar depression. Is it divisible into autonomous subtypes? Arch. Gen. Psychiatry 36: 47.
62. Winokur, G., P.J. Clayton, and R. Reich. 1969. Manic-depressive illness. C.V. Mosby, St. Louis, Missouri.
63. Winokur, G., M. Tsuang, and R.R. Crowe. 1982. The Iowa 500: Affective disorder in relatives of manic and depressed patients. Am J. Psychiatry 139: 209.
64. Winokur, G., R. Cadoret, J. Dorzab, and M. Baker. 1971. Depressive disease. A genetic study. Arch. Gen. Psychiatry 24: 135.