-
1
-
-
0025847083
-
The influence of age on salicylate pharmacokinetics in humans
-
ABDALLAH, H. Y., MAYERSON, M. AND CONTRAD, K. A.: The influence of age on salicylate pharmacokinetics in humans. J. Clin. Pharmacol. 31: 380-387, 1991.
-
(1991)
J. Clin. Pharmacol.
, vol.31
, pp. 380-387
-
-
Abdallah, H.Y.1
Mayerson, M.2
Contrad, K.A.3
-
2
-
-
0027953515
-
Studies of the biochemical toxicology of uranyl nitrate
-
ANTHONY, M. L., GARTLAND, K. P. R., BEDDELL, C. R., LINDON, J. C. AND NICHOLSON J. K.: Studies of the biochemical toxicology of uranyl nitrate. Arch. Toxicol. 88: 43-53, 1994.
-
(1994)
Arch. Toxicol.
, vol.88
, pp. 43-53
-
-
Anthony, M.L.1
Gartland, K.P.R.2
Beddell, C.R.3
Lindon, J.C.4
Nicholson, J.K.5
-
3
-
-
0027199712
-
Predictability of the covalent binding of acidic drugs in man
-
BENET, L. Z., SPAHN-LANGGUTH, H., IWAKAWA, S., VOLLAND, C., MIZUMA, T., MAYER, S., MUTSCHLER, E. AND LIN, E. T.: Predictability of the covalent binding of acidic drugs in man. Life Sci. 53: 141-146, 1993.
-
(1993)
Life Sci.
, vol.53
, pp. 141-146
-
-
Benet, L.Z.1
Spahn-Langguth, H.2
Iwakawa, S.3
Volland, C.4
Mizuma, T.5
Mayer, S.6
Mutschler, E.7
Lin, E.T.8
-
4
-
-
0018828618
-
Renal clearance of salicylic acid and salicyluric acid in the rat and in the isolated perfused rat kidney
-
BEKERSKY, I., FISHMAN, L., KAPLAN, S. A. AND COLBURN, W. A.: Renal clearance of salicylic acid and salicyluric acid in the rat and in the isolated perfused rat kidney. J. Pharmacol. Exp. Ther. 212: 309-314, 1980.
-
(1980)
J. Pharmacol. Exp. Ther.
, vol.212
, pp. 309-314
-
-
Bekersky, I.1
Fishman, L.2
Kaplan, S.A.3
Colburn, W.A.4
-
5
-
-
0022349614
-
Effect of probenecid on the renal tubular secretion of salicyluric acid by the isolated perfused rat kidney
-
BEKERSKY, I. AND OLEJNIK, N.: Effect of probenecid on the renal tubular secretion of salicyluric acid by the isolated perfused rat kidney. Drug Metab. Dispos. 13: 630-633, 1985.
-
(1985)
Drug Metab. Dispos.
, vol.13
, pp. 630-633
-
-
Bekersky, I.1
Olejnik, N.2
-
7
-
-
0018356414
-
Decreased binding of drugs and dyes to plasma proteins from rats with acute renal failure: Effects of ureter ligation and intramuscular injection of glycerol
-
BOWMER, C. J. AND LINDUP, W. E.: Decreased binding of drugs and dyes to plasma proteins from rats with acute renal failure: Effects of ureter ligation and intramuscular injection of glycerol. Br. J. Pharmacol. 66: 275-281, 1979.
-
(1979)
Br. J. Pharmacol.
, vol.66
, pp. 275-281
-
-
Bowmer, C.J.1
Lindup, W.E.2
-
8
-
-
0025761679
-
Renal handling and effects of salicylic acid in the isolated perfused rat kidney
-
COX, P. G. F., MOONS, W. M., RUSSEL, F. G. M. AND VAN GINNEKEN, C. A. M.: Renal handling and effects of salicylic acid in the isolated perfused rat kidney. Pharmacol. Toxicol. 69: 322-328, 1991.
-
(1991)
Pharmacol. Toxicol.
, vol.69
, pp. 322-328
-
-
Cox, P.G.F.1
Moons, W.M.2
Russel, F.G.M.3
Van Ginneken, C.A.M.4
-
9
-
-
0024586649
-
The pharmacokinetics of salicylate in the pregnant Wistar rat
-
DEAN, M., PENGLIS, S. AND STOCK, B.: The pharmacokinetics of salicylate in the pregnant Wistar rat. Drug Metab. Dispos. 17: 87-90, 1989.
-
(1989)
Drug Metab. Dispos.
, vol.17
, pp. 87-90
-
-
Dean, M.1
Penglis, S.2
Stock, B.3
-
10
-
-
0028208711
-
Studies on the reactivity of acyl glucuronides. VII. Salicyl acyl glucuronide reactivity in vitro and covalent binding of salicylic acid to plasma protein of humans taking aspirin
-
DICKINSON, R. G., BAKER, P. V. AND KING, A. R.: Studies on the reactivity of acyl glucuronides. VII. Salicyl acyl glucuronide reactivity in vitro and covalent binding of salicylic acid to plasma protein of humans taking aspirin. Biochem. Pharmacol. 47: 469-476, 1994.
-
(1994)
Biochem. Pharmacol.
, vol.47
, pp. 469-476
-
-
Dickinson, R.G.1
Baker, P.V.2
King, A.R.3
-
11
-
-
0021707968
-
Properties of acyl glucuronides: Implications for studies of the pharmacokinetics and metabolism of acidic drugs
-
FAED, E. M.: Properties of acyl glucuronides: Implications for studies of the pharmacokinetics and metabolism of acidic drugs. Drug Metab. Rev. 15: 1213-1249, 1984.
-
(1984)
Drug Metab. Rev.
, vol.15
, pp. 1213-1249
-
-
Faed, E.M.1
-
12
-
-
0019422408
-
Evaluation of methods for producing renal dysfunction in rats
-
GIACOMINI, K. M., ROBERTS, S. M. AND LEVY, G.: Evaluation of methods for producing renal dysfunction in rats. J. Pharmaceut. Sci. 70: 117-121, 1981.
-
(1981)
J. Pharmaceut. Sci.
, vol.70
, pp. 117-121
-
-
Giacomini, K.M.1
Roberts, S.M.2
Levy, G.3
-
14
-
-
0019995539
-
Apparent intramolecular acyl migration of zomepirac glucuronide
-
HASEGAWA, J., SMITH, P. C. AND BENET, L. Z.: Apparent intramolecular acyl migration of zomepirac glucuronide. Drug Metab. Dispos. 10: 469-473, 1982.
-
(1982)
Drug Metab. Dispos.
, vol.10
, pp. 469-473
-
-
Hasegawa, J.1
Smith, P.C.2
Benet, L.Z.3
-
15
-
-
0022222072
-
The effects of age and sex on the disposition of acetyl salicylic acid and its metabolites
-
HO, P. C., TRIGGS, E. J. AND BOURNE, W. A.: The effects of age and sex on the disposition of acetyl salicylic acid and its metabolites. Br. J. Pharmacol. 18: 675-684, 1985.
-
(1985)
Br. J. Pharmacol.
, vol.18
, pp. 675-684
-
-
Ho, P.C.1
Triggs, E.J.2
Bourne, W.A.3
-
16
-
-
0023900516
-
Effect of pH on acyl migration and hydrolysis of tometin glucuronide
-
HYNECK, M. L., MUNAFO, A. AND BENET, L. Z.: Effect of pH on acyl migration and hydrolysis of tometin glucuronide. Drug Metab. Dispos. 16: 322-324, 1988.
-
(1988)
Drug Metab. Dispos.
, vol.16
, pp. 322-324
-
-
Hyneck, M.L.1
Munafo, A.2
Benet, L.Z.3
-
17
-
-
0020080143
-
Gastrointestinal and hepatic firstpass metabolism of aspirin in rats
-
IWAMOTO, K, TAKEI, M. AND WATANABE, J.: Gastrointestinal and hepatic firstpass metabolism of aspirin in rats. J. Pharm. Pharmacol. 34: 176-180, 1982.
-
(1982)
J. Pharm. Pharmacol.
, vol.34
, pp. 176-180
-
-
Iwamoto, K.1
Takei, M.2
Watanabe, J.3
-
18
-
-
0018635740
-
Pharmacokinetics of salicylate in man
-
LEVY, G.: Pharmacokinetics of salicylate in man. Drug Metab. Rev. 9: 3-19, 1979.
-
(1979)
Drug Metab. Rev.
, vol.9
, pp. 3-19
-
-
Levy, G.1
-
19
-
-
0030050780
-
Direct analysis of salicylic acid, salicylate acyl glucuronide, salicyluric acid and gentisic acid in human plasma and urine by high performance liquid chromatography
-
LIU, J. H. AND SMITH, P. C.: Direct analysis of salicylic acid, salicylate acyl glucuronide, salicyluric acid and gentisic acid in human plasma and urine by high performance liquid chromatography. J. Chromatogr. 675: 61-70, 1996.
-
(1996)
J. Chromatogr.
, vol.675
, pp. 61-70
-
-
Liu, J.H.1
Smith, P.C.2
-
20
-
-
0016224864
-
Kinetics of salicylate elimination in anephric patients
-
LOWENTHAL, D. T., BRIGGS, W. A. AND LEVY, G.: Kinetics of salicylate elimination in anephric patients. J. Clin. Invest. 54: 1221-1226, 1974.
-
(1974)
J. Clin. Invest.
, vol.54
, pp. 1221-1226
-
-
Lowenthal, D.T.1
Briggs, W.A.2
Levy, G.3
-
21
-
-
0021918123
-
Clinical pharmacokinetics of the salicylates
-
NEEDS, C. J. AND BROOKS, P. M.: Clinical pharmacokinetics of the salicylates. Clin. Pharmacokinetics 10: 164-177, 1985
-
(1985)
Clin. Pharmacokinetics
, vol.10
, pp. 164-177
-
-
Needs, C.J.1
Brooks, P.M.2
-
22
-
-
0013927465
-
Comparative pharmacokinetics of salicylate elimination in man and rats
-
NELSON, E., HANABU, M. AND LEVY, G.: Comparative pharmacokinetics of salicylate elimination in man and rats. J. Pharmacol. Exp. Ther. 153: 159-166, 1966.
-
(1966)
J. Pharmacol. Exp. Ther.
, vol.153
, pp. 159-166
-
-
Nelson, E.1
Hanabu, M.2
Levy, G.3
-
23
-
-
0025179702
-
Comparative metabolism of high doses of aspirin in man and rat
-
PATEL., D. K., NOTARIANNI, L. J. AND BENNETT, P. N.: Comparative metabolism of high doses of aspirin in man and rat. Xenobiotica 20: 847-854, 1990.
-
(1990)
Xenobiotica
, vol.20
, pp. 847-854
-
-
Patel, D.K.1
Notarianni, L.J.2
Bennett, P.N.3
-
24
-
-
0019189250
-
Differentiation of various experimentally-induced pathological processes in Wistar rats by serum protein electrophoresis using cellulose-acetate membranes
-
ROTHKOPF-ISCHEBECK, M.: Differentiation of various experimentally-induced pathological processes in Wistar rats by serum protein electrophoresis using cellulose-acetate membranes. Lab. Animals 14: 153-165, 1980.
-
(1980)
Lab. Animals
, vol.14
, pp. 153-165
-
-
Rothkopf-Ischebeck, M.1
-
25
-
-
0343977708
-
The chemical estimation of acyl glucuronides and its application to studies on the metabolism of benzoate and salicylate in man
-
SCHACHTER, D.: The chemical estimation of acyl glucuronides and its application to studies on the metabolism of benzoate and salicylate in man. J. Clin. Invest. 36: 297-302, 1957.
-
(1957)
J. Clin. Invest.
, vol.36
, pp. 297-302
-
-
Schachter, D.1
-
26
-
-
0006788437
-
Salicylate and salicyl conjugates: Fluorimetric estimation, biosynthesis and renal excretion in man
-
SCHACHTER, D. AND MANIS, J. G.: Salicylate and salicyl conjugates: Fluorimetric estimation, biosynthesis and renal excretion in man. J. Clin. Invest. 37: 800-807, 1958.
-
(1958)
J. Clin. Invest.
, vol.37
, pp. 800-807
-
-
Schachter, D.1
Manis, J.G.2
-
27
-
-
0028303466
-
Evaluation of hepatic metabolism of salicylic acid in perfused rat liver
-
SHETTY, B. V., BADR, M. AND MELETHIL, S.: Evaluation of hepatic metabolism of salicylic acid in perfused rat liver. J. Pharm. Sci. 83: 607-608, 1994.
-
(1994)
J. Pharm. Sci.
, vol.83
, pp. 607-608
-
-
Shetty, B.V.1
Badr, M.2
Melethil, S.3
-
28
-
-
0025116545
-
Covalent binding of zomepirac glucuronide to proteins: Evidence for a Schiff base mechanism
-
SMITH, P. C., BENET, L. Z. AND MCDONAGH, A. F.: Covalent binding of zomepirac glucuronide to proteins: Evidence for a Schiff base mechanism. Drug Metab. Dispos. 18: 639-644, 1990.
-
(1990)
Drug Metab. Dispos.
, vol.18
, pp. 639-644
-
-
Smith, P.C.1
Benet, L.Z.2
Mcdonagh, A.F.3
-
29
-
-
0021961277
-
Stability of acyl glucuronides in biological fluids: Studies with zomepirac
-
SMITH, P. C., HASEGAWA, J., LANGENDIJK, P. N. J. AND BENET, L. Z.: Stability of acyl glucuronides in biological fluids: Studies with zomepirac. Drug Metab. Dispos. 13: 110-112, 1985.
-
(1985)
Drug Metab. Dispos.
, vol.13
, pp. 110-112
-
-
Smith, P.C.1
Hasegawa, J.2
Langendijk, P.N.J.3
Benet, L.Z.4
-
30
-
-
0027158963
-
Covalent binding of suprofen acyl glucuronide to albumin in vitro
-
SMITH, P. C. AND LIU, J. H.: Covalent binding of suprofen acyl glucuronide to albumin in vitro. Xenobiotica 23: 337-348, 1993.
-
(1993)
Xenobiotica
, vol.23
, pp. 337-348
-
-
Smith, P.C.1
Liu, J.H.2
-
31
-
-
0029013346
-
Covalent binding of suprofen to renal tissue of rats correlates with excretion of its acyl glucuronide
-
SMITH, P. C. AND LIU, J. H.: Covalent binding of suprofen to renal tissue of rats correlates with excretion of its acyl glucuronide. Xenobiotica 25: 531-540, 1995.
-
(1995)
Xenobiotica
, vol.25
, pp. 531-540
-
-
Smith, P.C.1
Liu, J.H.2
-
32
-
-
0022477143
-
Irreversible binding of zomepirac to plasma protein in vitro and in vivo
-
SMITH, P. C., MCDONAGH, A. F. AND BENET, L. Z.: Irreversible binding of zomepirac to plasma protein in vitro and in vivo. J. Clin. Invest. 77: 934-939, 1986.
-
(1986)
J. Clin. Invest.
, vol.77
, pp. 934-939
-
-
Smith, P.C.1
Mcdonagh, A.F.2
Benet, L.Z.3
-
33
-
-
0026532030
-
Acyl glucuronides revisited: Is the glucuronidation process a toxification as well as a detoxification mechanism?
-
SPAHN-LANGGUTH, H. AND BENET, L. Z.: Acyl glucuronides revisited: Is the glucuronidation process a toxification as well as a detoxification mechanism? Drug Metab. Rev. 24: 5-48, 1992.
-
(1992)
Drug Metab. Rev.
, vol.24
, pp. 5-48
-
-
Spahn-Langguth, H.1
Benet, L.Z.2
-
34
-
-
0023553599
-
Proposed mechanisms of aspirin sensitivity reactions
-
STEVENSON, D. D AND LEWIS, R. A.: Proposed mechanisms of aspirin sensitivity reactions. J. Aller. Clin. Immunol. 80: 788-790, 1987.
-
(1987)
J. Aller. Clin. Immunol.
, vol.80
, pp. 788-790
-
-
Stevenson, D.D.1
Lewis, R.A.2
-
35
-
-
0021847237
-
Acylation of albumin by 1-O-acyl glucuronides
-
VAN BREEMAN, R. B. AND FENSELAU, C.: Acylation of albumin by 1-O-acyl glucuronides. Drug Metab. Dispos. 13: 318-320, 1985.
-
(1985)
Drug Metab. Dispos.
, vol.13
, pp. 318-320
-
-
Van Breeman, R.B.1
Fenselau, C.2
-
36
-
-
0015386488
-
Renal contribution to overall metabolism of drugs. II. Biotranaformation of salicylic acid to salicyluric acid
-
WAN, S. H. AND RIEGELMAN, S.: Renal contribution to overall metabolism of drugs. II. Biotranaformation of salicylic acid to salicyluric acid. J. Pharm. Sci. 61: 1284-1287, 1972.
-
(1972)
J. Pharm. Sci.
, vol.61
, pp. 1284-1287
-
-
Wan, S.H.1
Riegelman, S.2
-
37
-
-
0026583192
-
Studies of the reactivity of acyl glucuronides. III. Glucuronide-derived adducts of valproic acid and plasma protein and anti-adduct antibodies in humans
-
WILLIAMS, A. M., WORRALL, S., JERSEY, J. D. AND DICKINSON, R. G.: Studies of the reactivity of acyl glucuronides. III. Glucuronide-derived adducts of valproic acid and plasma protein and anti-adduct antibodies in humans. Biochem. Pharmacol. 43: 745-755, 1992.
-
(1992)
Biochem. Pharmacol.
, vol.43
, pp. 745-755
-
-
Williams, A.M.1
Worrall, S.2
Jersey, J.D.3
Dickinson, R.G.4
-
38
-
-
0028951167
-
Rat serum albumin modified by diflunisal acyl glucuronide is immunogenic in rats
-
WORRALL, S. AND DICKINSON, R. G.: Rat serum albumin modified by diflunisal acyl glucuronide is immunogenic in rats. Life Sci. 56: 1921-1930, 1995.
-
(1995)
Life Sci.
, vol.56
, pp. 1921-1930
-
-
Worrall, S.1
Dickinson, R.G.2
-
39
-
-
0017683821
-
Intraindividual relationships between protein binding of drugs in normal human subjects, patients with impaired renal function, and rats
-
YACOBI, A. AND LEVY, G.: Intraindividual relationships between protein binding of drugs in normal human subjects, patients with impaired renal function, and rats. J. Pharmaceut. Sci. 66: 1285-1288, 1977.
-
(1977)
J. Pharmaceut. Sci.
, vol.66
, pp. 1285-1288
-
-
Yacobi, A.1
Levy, G.2
-
40
-
-
0020049680
-
Pharmacokinetics, metabolism and disposition of salicylate in protein deficient rats
-
YUE, T. L. AND VARMA, D. R.: Pharmacokinetics, metabolism and disposition of salicylate in protein deficient rats. Drug Metab. Dispos. 10: 147-152, 1982.
-
(1982)
Drug Metab. Dispos.
, vol.10
, pp. 147-152
-
-
Yue, T.L.1
Varma, D.R.2
-
41
-
-
0028951036
-
Hypersensitivity to nonsteroidal anti-inflammatory drugs
-
ZIA-AMIRHOSSEINI, P., HARRIS, R. Z., BRODSKY, F. M. AND BENET, L. Z.: Hypersensitivity to nonsteroidal anti-inflammatory drugs. Natl. Med. 1: 2-4, 1995.
-
(1995)
Natl. Med.
, vol.1
, pp. 2-4
-
-
Zia-Amirhosseini, P.1
Harris, R.Z.2
Brodsky, F.M.3
Benet, L.Z.4
-
42
-
-
0027976283
-
Enhanced covalent binding of tolmetin to proteins in humans after multiple dosing
-
ZIA-AMIHHOSSEINI, P., OJINGWA, J. C., SPAHN-LANGGUTH, H., MCDONAGH, A. F. AND BENET, L. Z.: Enhanced covalent binding of tolmetin to proteins in humans after multiple dosing. Clin. Pharmacol. Ther. 55: 21-27, 1994.
-
(1994)
Clin. Pharmacol. Ther.
, vol.55
, pp. 21-27
-
-
Zia-Amihhosseini, P.1
Ojingwa, J.C.2
Spahn-Langguth, H.3
Mcdonagh, A.F.4
Benet, L.Z.5
|