Neutrophils and the adaptive immune response to Candida albicans

Research in Immunology

Volumn 147, Issue 8-9, 1996, Pages 512-518

  Romani, L ^a   Mencacci, A ^a   Cenci, E ^a   Puccetti, P ^b   Bistoni, F ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

^b Pharmacol Sect of the Univ of T   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CANDIDA ALBICANS VACCINE; INTERLEUKIN 10; INTERLEUKIN 12;

CANDIDA ALBICANS; CANDIDIASIS; CONFERENCE PAPER; HELPER CELL; IMMUNOREGULATION; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

EID: 0030440484     PISSN: 09232494     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0923-2494(97)85216-9     Document Type: Conference Paper

References (43)

1. Ashman, R.B. & Papadimitriou, J.M. (1991), Susceptibility of beige mutant mice to candidiasis may be linked to a defect in granulocyte production by bone marrow stem cells. Infect. Immun., 59, 2140-2146.
2. Ashman, R.B. & Papadimitriou, J.M. (1995), Production and function of cytokines in natural and acquired immunity to Candida albicans. Microbiol. Rev., 59, 646-672.
3. Bodey, G.P., Buckley, M., Sathe, Y.S. & Freireich, E.J. (1966), Quantitative relationships between circulating leukocytes and infection in patients with acute leukemia. Ann. Inter. Med., 64, 328-340.
4. Campbell, P.A. (1990), The neutrophil, a professional killer of bacteria, may be controlled by T cells. Clin. Exp. Immunol., 79, 141-143.
5. Cassatella, M.A. (1995), The production of cytokines by polymorphonuclear neutrophils. Immunol. Today, 16, 21-26.
6. Cassatella, M.A., Meda, L., Gasperini, S., D'Andrea, A., Ma, X. & Trinchieri, G. (1995), Interleukin-12 production by human polymorphonuclear leukocytes. Eur. J. Immunol., 25, 1-5.
7. Cenci, E., Romani, L., Mencacci, A., Spaccapelo, R., Schiaffella, E., Puccetti, P. & Bistoni, F. (1993), Interleukin-4 and interleukin-10 inhibit nitric oxide-dependent macrophage killing of Candida albicans. Eur. J. Immunol., 23, 1034-1038.
8. Conlan, J.W. & North, R.J. (1994), Neutrophils are essential for early anti-Listeria defense in the liver, but not in the spleen or the peritoneal cavity as revealed by a granulocyte-depleting monoclonal antibody. J. Exp. Med., 179, 259-268.
9. Cutler, J.E. (1991), Putative virulence factors of Candida albicans, Annu, Rev. Microbiol., 45, 187-218.
10. Diamond, R.D., Clark, R.A. & Haudenschild, C.C. (1980), Damage to Candida albicans hyphae and pseudohyphae of the myeloperoxidase system and oxidative products of neutrophil metabolism in vitro. J. Clin. Invest., 66, 908-917.
11. Djeu, J.Y. (1993), Modulators of immune responses to fungi, in "Fungal infections and immune responses" (Murphy, J.W., Friedman, H., Bendinelli, M.) (pp. 521-532). Plenum Press, New York.
12. Djeu, J.Y., Lieu, J.H., Wei, S., Rui, H., Pearson, C.A., Leonard, W.L. & Blanchard, D.K. (1993), Function associated with IL-2 receptor β on human neutrophils. Mechanism of activation of antifungal activity against Candida albicans by IL-2. J. Immunol., 150, 960-970.
13. Fidel, P.L., Jr. & Sobel, J.D. (1994), The role of cell-mediated immunity in candidiasis. Trends Microbiol., 6, 202-206.
14. Finkelman, F.D., Madden, K.B., Cheever, A.W., Katona, I.M., Morris, S.C., Gately, M.K., Hubbard, B.R., Gause, W.C. & Urban, J.F., Jr. (1994), Effects of interleukin 12 on immune response and host protection in mice with intestinal nematode parasites. J. Exp. Med., 179, 1563-1572.
15. Fossiez, F., Djossou, O., Chomarat, P., Romo-Flores, L., Ait-Yahia, S., Maat, C., Pin, J.J., Garrone, P., Garcia, E., Saeland, S., Blanchard, D., Gaillard, C., Das Mahapatra, B., Rouvier, E., Golstein, P., Banchereau, J. & Lebeque, S. (1996), T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines. J. Exp. Med., 183, 2593-2603.
16. Heufler, C., Koch, F., Stanzl, U., Topar, G., Wysocka, M., Trinchieri, G., Enk, A., Steinman, R.M., Romani, N. & Schuler, G. (1996), Interleukin-12 is produced by dendritic cells and mediates T helper 1 development as well as interferon-γ production by T helper 1 cells. Eur. J. Immunol., 26, 659-668.
17. Jensen, J., Warner, T. & Balish, E. (1993), Resistance of SCID mice to Candida albicans administered intravenously or colonizing the gut: role of polymorphonuclear leukocytes and macrophages. J. Infect. Dis., 167, 912-919.
18. Lehrer, R.I. (1970), Measurement of candidacidal activity of specific leukocytes types in mixed cell populations. - I. Normal myeloperoxidase deficient and chronic granulomatous disease neutrophils. Infect. Immun., 2, 42-47.
19. Lilic, D., Cant, A.J., Abinun, M., Calvert, J.E. & Spickett, G.P. (1996a), Chronic mucocutaneous candidiasis. -I. Altered antigen-stimulated IL-2, IL-4, IL-6 and interferon-gamma (IFN-γ) production. Clin. Exp. Immunol., 105, 205-212.
20. Lilic, D., Cant, A.J., Abinun, M., Calvert, J.E. & Spickett, G.P (1996b), Chronic mucocutaneous candidiasis. -II. Class and subclass of antibody responses in vivo and in vitro. Clin. Exp. Immunol., 105, 205-212.
21. Lloyd, A.R. & Oppenheim, J.J. (1992), Poly's lament. The neglected role of polymorphonuclear neutrophil in different limbs of the immune response. Immunol. Today, 13, 169-172.
22. Mencacci, A., Cenci, E., Boclaert, J.R., Bucci, P., Mosci, P., Fé d'Ostiani, C., Bistoni, F. & Romani, L. (1997), Iron overload alters innate and T helper cell responses to Candida albicans in mice. J. Infect. Dis. (in press).
23. Mencacci, A., Cenci, E., Spaccapelo, R., Tonnetti, L., Del Sero, G., Fe d'Ostani, C., Bistoni, F. & Romani, L. (1996a), Neutrophils producing IL-10 antagonize the effect of IL-12 in mice with candidiasis, in Annals of the New York Academy of Sciences (in press).
24. + T-helper-cell responses in mice with low-level Candida albicans infection. Infect. Immun., 64, 4907-4914.
25. Nelson, R.D., Shibata, N., Podzorski, R.P. & Herron, M.J. (1991), Candida mannan: Chemistry, suppression of cell-mediated immunity, and possible mechanisms of action. Clin. Microbiol. Rev., 4, 1-19.
26. Odds, F.C. (1988), Candida and candidosis, 2nd ed. (pp. 124-152). Baillière-Tindall, London.
27. Pericle, F., Liu, J.H., Diaz, J.I., Blanchard, D.K., Wei, S., Forni, G. & Djeu, J.Y. (1994), Interleukin-2 prevention of apoptosis in human neutrophils. Eur. J. Immunol., 24, 440-444.
28. Puccetti, P., Romani, L. & Bistoni, F. (1995), A TH1-TH2-like switch in candidiasis: new perspectives for therapy. Trends Microbiol., 3, 237-240.
29. Rogers, H.W. & Unanue, E.R. (1993), Neutrophils are involved in acute, nonspecific resistance to Listeria monocytogenes in mice. Infect. Immun., 61, 5090-5096.
30. Romani, L., Bistoni, F., Mencacci, A., Cenci, E., Spaccapelo, R. & Puccetti, P. (1995a), IL12 in Candida albicans infections, in "62nd Forum on Immunology" (G. Trinchieri and P. Scott). Res. Immunol., 146, 532-538.
31. Romani, L. & Howard, D.H. (1995), Mechanisms of resistance to fungal infections. Curr. Opin. Immunol, 7, 517-523.
32. + T helper subset selection in mice with candidiasis. J. Immunol. (in press).
33. + T helper cell 1 development in interleukin 6-deficient mice infected with Candida albicans. J. Exp. Med., 183, 1345-1355.
34. Romani, L., Mencacci, A., Tonnetti, L., Spaccapelo, R., Cenci, E., Puccetti, P., Wolf, S.F. & Bistoni, F. (1994a), Interleukin-12 is both required and prognostic in vivo for T helper type 1 differentiation in murine candidiasis. J. Immunol., 153, 5167-5175.
35. Romani, L., Mocci, S., Bietta, C., Lanfaloni, L., Puccetti, P. & Bistoni, F. (1991), Th1 and Th2 cytokine secretion patterns in murine candidiasis: association of Th1 responses with acquired resistance. Infect. Immun., 59, 4647-4654.
36. Romani, L., Puccetti, P. & Bistoni, F. (1995b), Biological role of helper T-cell subsets in candidiasis. Chem. Immunol., 63, 113-137.
37. Romani, L., Puccetti, P., Mencacci, A., Cenci, E., Spaccapelo, R., Tonnetti, L., Grohmann, U. & Bistoni, F. (1994b), Neutralization of IL-10 upregulates nitric oxide production and protects susceptible mice from challenge with Candida albicans. J. Immunol., 152, 3514-3521.
38. Savolainen, J., Koivikko, A., Kalimo, K., Nieminen, E. & Viander, M. (1990), IgE, IgA and IgG antibodies and delayed skin responses towards Candida albicans antigens in atopics with and without saprophytic growth. Clin. Exp. Allergy, 20, 549-554.
39. Schaffner, A., Davis, C.E., Schaffner, T., Markert, M., Douglas, H. & Braude, A.I. (1986), In vitro susceptibility of fungi to killing by neutrophil granulocytes discriminates between primary pathogenicity and opportunism. J. Clin. Invest., 78, 511-524.
40. Spaccapelo, R., Del Sero, G., Mosci, P., Bistoni, F. & Romani, L. (1997), Early T cell unresponsiveness in mice with candidiasis and reversal by IL-2. Effect on T helper cell development. J. Immunol. (in press).
41. Walsh, T.J., Hiemenz, J. & Pizzo, P.A. (1994), Evolving risk factors for invasive fungal infections. All neutropenic patients are not the same. Clin. Infect. Dis., 18, 793-798.
42. Witkin, S.S., Jeremias, J. & Ledger, W.J. (1989), Vaginal eosinophils and IgE antibodies to Candida albicans in women with recurrent vaginitis. J. Med. Vet. Mycol., 27, 57-58.
43. Wynn, T.A., Eltoum, I., Oswald, I.P., Cheever, A.W. & Sher, A. (1994), Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma Mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology. J. Exp. Med., 179, 1551-1561.