Neurotrophin-3 gene polymorphisms and schizophrenia: No evidence for linkage or association

Psychiatric Genetics

Volumn 6, Issue 4, 1996, Pages 183-186

  Gill, M ^a,e   Hawi, Z ^a   O'Neill, F A ^b   Walsh, D ^c   Straub, R E ^d   Kendler, K S ^d  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^c HEALTH RESEARCH BOARD   (Ireland)

^d VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e ST JAMES S HOSPITAL   (Ireland)

Author keywords

Association; Genetics; Linkage; Schizophrenia

Indexed keywords

NEUROTROPHIN 3;

ALLELE; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; GENE MUTATION; GENETIC LINKAGE; HUMAN; MAJOR CLINICAL STUDY; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NEUROPATHOLOGY; PRIORITY JOURNAL; PROMOTER REGION; SCHIZOPHRENIA; TEMPORAL LOBE;

EID: 0030440205     PISSN: 09558829     EISSN: None     Source Type: Journal    
DOI: 10.1097/00041444-199624000-00002     Document Type: Article

References (18)

1. Barde YA (1989) Trophic factors and neuronal survival, Neuron, 2, 1525-1534.
2. Bogerts B (1993) Recent advances in the neuropathology of schizophrenia. Schizophrenia Bulletin, 19, 431-445.
3. Bogerts B, Meertz E and Schonfeldt-Bausch R (1985) Basal ganglia and limbic system pathology in schizophrenia: A morphometric study of brain volume and shrinkage. Archives of General Psychiatry, 42, 784-791.
4. Brown R, Colter M, Corsellis JAN, Crow TJ, Frith CD, Johnstone EC, Owens DG and Roberts GW (1986) Postmortem evidence of structural brain changes in schizophrenia. Archives of General Psychiatry, 43, 36-42.
5. Dawson E, Powell JF, Sham PC, Nothen M, Crocq M-A, Propping P, Korner J, Rietschel M, van Os J, Wright P, Murray RM and Gill M (1995) An association study of a neurotrophin-3 (NT-3) gene polymorphism with schizophrenia. Acta Psychiatrica Scandinavica, in press.
6. Eagles JM, Gibson I, Bremner MH, Clunie F, Ebmeier KP and Smith NC (1990) Obstetric complications in DSM-III schizophrenics and their siblings. Lancet, 335, 1139-1141.
7. Hattori M and Nanko S (1995) Association of neurotrophin-3 gene variant with severe forms of schizophrenia. Biochemical and Biophysical Research Communications, 209, 513-518.
8. Kendler KS, Lieberman JA and Walsh D (1989) The structures interview for schizotypy (SIS): a preliminary report. Schizophrenia Bulletin, 15, 559-571.
9. Kendler KS, O'Neill FA, Bourke J, Murphy B, Duke F, Straub RE, Shinkwin R, Ni Nuallain M, MacLean CJ and Walsh D (1996) The Irish Study of high density schizophrenia families: field methods and power to detect linkage. Neuropsychiatric Genetics, 57, 179-190.
10. deKok YJ, van der Maarel SM, Bitner-Glindzicz M, Huber I, Monaco A, Malcome S, Pembrey M, Ropers H-H and Cremers FP (1995) Association between X-linked mixed deafness and mutations in the POLJ domain gene POU3F4. Science, 267, 685-687.
11. Maisonpierre PC, Belluscio L, Friedman B, Alderson RF, Wigund SJ, Furth ME, Lindsay R and Yancopoulos GD (1990) NT3, BDNF and NGF in the developing rat nervous system: parallel as well as reciprocal patterns of expression. Neuron, 5, 501-509.
12. Nanko S, Hattori M, Kuwara S, Sasaki T, Fukuda R, Dai XY, Yarnaguchi K, Shibata Y and Kazamatsuri H (1994) Neurotrophin-3 gene polymorphism associated with schizophrenia. Acta Psychiatrica Scandinavica, 89, 390-392.
13. O'Callaghan E, Sham P, Glover G, Takei N and Murray R (1991) Schizophrenia after prenatal exposure to the 1959 A2 influenza epidemic. Lancet, 377, 1248-1250
14. O'Callaghan E, Gibson T, Colohan HA, Buckley P, Walsh DG, Larking C, Waddington JL (1992) Risk of schizophrenia in adults born after obstetric complications and their association with early onset of illness: a case controlled study. British Medical Journal. 305, 1256-1259.
15. Spitzer RL, Williams JB, Gibbon M and First MB (1992) the structured clinical interview for DSM-III-R (SCID): History, rationale, and description. Archives of General Psychiatry, 49, 624-629.
16. Straub R, MacLean C, O'Neill A, Burke J, Murphy B, Duke F, Shinkwin R, Webb B, Zhang J, Walsh D and Kendler KS (1996) A potential vulnerability locus for schizophrenia on chromosome 6p24-22: evidence for genetic heterogeneity. Nature Genetics, 11, 287-292.
17. Susser ES and Lin SP (1992) Schizophrenia after prenatal exposure to the Dutch hunger winter of 1944-1945. Archives of General Psychiatry, 49, 983-988.
18. Wright P, Gill M and Murray RM (1993) Genetics and the maternal immune response to viral infection. American Journal of Medical Genetics (Neuropsychiatrie Genetics), 48, 40-46.