Specific serological response by active immunization with GD3-bearing liposomes

Journal of Pharmacology and Experimental Therapeutics

Volumn 278, Issue 3, 1996, Pages 1114-1120

  Masso O ^a,c   Alino S F ^b   Lejarreta, M ^b   Blasco, F ^a   Piulats, J ^a  

^a Laboratorio de Bioinvestigación   (Spain)

^b UNIVERSITY OF VALENCIA   (Spain)

^c S A Laboratorio de Bioinvestigacion   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; DICETYL PHOSPHATE; FREUND ADJUVANT; GANGLIOSIDE GD3; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LIPOSOME; PERTUSSIS VACCINE; SPHINGOMYELIN; VACCINE;

ACTIVE IMMUNIZATION; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; BORDETELLA PERTUSSIS; DRUG FORMULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOGENICITY; IMMUNOREACTIVITY; INTRAPERITONEAL DRUG ADMINISTRATION; LIPID COMPOSITION; MOUSE; PRIORITY JOURNAL; SALMONELLA MINNESOTA;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODY FORMATION; CANCER VACCINES; FLOW CYTOMETRY; GANGLIOSIDES; HUMANS; IMMUNITY, CELLULAR; LIPOSOMES; MELANOMA; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; TUMOR CELLS, CULTURED;

EID: 0030437933     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. ALIÑO, S. F., LEJARRETA, M., ALFARO, J., IRUARRIZAGA, A., BOBADILLA, M., BLAYA, C. AND CRESPO, J.: Antimetastasic effect of immunization with liposome-encapsulated tumor cell-membrane proteins obtained from experimental tumors. Immunopharmacol. Immunotoxicol. 17: 419-436, 1995.
2. ALVING, C. R.: Liposomes as carriers of antigens and adjuvants. J. Immunol. Meth. 140: 1-13, 1991.
3. BANGHAM, A. D.: Membrane models with phospholipids. Prog. Biophys. Mol. Biology 18: 29-33, 1968.
4. CHEUNG, H. K. V., LAZARUS, H., MIRALDI, F. D., ABRAMOWSKI, C. R., KALLICK, S. AND SAARINEN, U. M.: Ganglioside GD2 specific monoclonal antibody 3F8: A phase I study in patients with neuroblastoma and malignant melanoma. J. Clin. Oncol. 5: 1430-1441, 1987.
5. DIPPOLD, W. G., BERNHARD, H., DIENES, H. P. AND MEYER, K.: Treatment of patients with malignant melanoma by monoclonal antibodies against gangliosides. Eur. J. Cancer Clin. Oncol. 24: 67-77, 1988.
6. GARCON, N. M. AND SIX, H. R.: Universal vaccine carrier. Liposomes that provide T-dependent help to weak antigens. J. Immunol. 146: 3697-3707, 1991.
7. GREGORIADIS, G.: Immunological adjuvants: A role for liposomes. Immunol. Today 11: 89-97, 1990.
8. HARADA, Y., SAAKTSUME, M., NORES, G. AND HAKOMORI, S.: Density of GM3 with normal primary structure determines mouse melanoma antigenicity. Jpn. J. Cancer Res. 80: 988-992, 1989.
9. HELLING, F., SHANG, A., CALVES, M., ZHANG, S., REN, S., YU, R. K., OETTGEN, H. F. AND LIVINGSTON, P. O.: GD3 vaccines for melanoma: Superior immunogenicity of Keyhole Limpet Hemocyanin conjugate vaccines. Cancer Res. 54: 197-203, 1994.
10. LIVINGSTON, P. O., CALVES, M. J., HELLING, F., ZOLLINGER, W. D., BLAKE, M. S. AND LOWELL, G. H.: GD3/proteosome vaccines induce consistent IgM antibodies against the ganglioside GD3. Vaccine 11: 1199-1204, 1993.
11. LIVINGSTON, P. O., CALVES, M. J. AND NATOLI, E. J.: Approaches to augmenting the immunogenicity of the ganglioside GM2 in mice: Purified GM2 is superior to whole cells. J. Immunol. 138: 1524-1529, 1987a.
12. LIVINGSTON, P. O., NATOLI, E. J., CALVES, M. J., STOCKERT, E., OETTGEN, H. F. AND OLD, L. I.: Vaccines containing purified GM2 ganglioside elicit GM2 antibodies in melanoma patients. Proc. Natl. Acad. Sci. U.S.A. 84: 2911-2915, 1987b.
13. LIVINGSTON, P. O., RITTER, G. AND CALVES, M. J.: Antibody response after immunization with ganglioside GM1, GM2, GM3, GD2 and GD3 in the mouse. Cancer Immunol. Immunother. 29: 179-184, 1989.
14. LLOYD, K. O. AND OLD, L. I.: Human monoclonal antibodies to glycolipids and other cancer antigens: Dissection of the humoral immune response in cancer patients. Cancer Res. 49: 3445-3451, 1989.
15. MASSÓ, O., ALIÑO, S. F., GOMEZ, A., MITJANS, F., BLASCO, F. AND PIULATS, J.: Immunogenicity of GD3 ganglioside associated in liposomes. Inmunologia 9: suppl. 1, 50-51, 1990.
16. NEW, R. R. C.: Preparation of liposomes. In Liposomes, a Practical Approach, ed. by R. R. C. New, pp. 33-39, IRL Press at Oxford University Press, Oxford, 1990a.
17. NEW, R. R. C.: Structure of liposomes, chemical constituents. In Liposomes, a Practical Approach, ed. by R. R. C. New, pp. 1-31, IRL Press at Oxford University Press, Oxford, 1990b.
18. RITTER, G., BOOSFELD, E., ADLURI, R., CALVES, M., OETTGEN, H. F., OLD, L. I. J. AND LIVINGSTON, PH.: Antibody responses to immunization with ganglioside GD3 and GD3 congeners (lactones, amide and gangliosidol) in patients with malignant melanoma. Int. J. Cancer 48: 379-385, 1991.
19. SELL, S.: Cancer associated carbohydrates identified by monoclonal antibodies. Hum. Pathol. 21: 1003-1019, 1990.
20. SINGHAL, A. AND HAKOMORI, S. I.: Molecular changes in carbohydrate antigens associated with cancer. Bioessays 12: 223-230, 1990.
21. TSUCHIDA, T., SAXTON, R. E., MORTON, D. L. AND IRIE, F.: Gangliosides of human melanoma. Cancer 63; 1166-1174, 1989.
22. VAN ROOIJEN, N. AND SU, S.: Immunoadjuvant action of liposomes. In Immunological Adyuvants and Vaccines, ed. by G. Gregoriadis, A. C. Allison, G. Poste, pp. 95-123 Plenum Press, New York, 1989.
23. WATARAI, S., HANDA, S., TADAKUMA, T. AND YASUDA, T.: Application of liposomes to generation of monoclonal antibody to glycosphigolipid: Production of monoclonal antibody to GgOse4Cer. J. Biochem. 102: 59-67, 1987.