Recombinant allergens for immunotherapy

Advances in Experimental Medicine and Biology

Volumn 409, Issue , 1996, Pages 85-93

  Thomas, W R ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; EPITOPE; HOUSE DUST ALLERGEN; IMMUNOGLOBULIN E; RECOMBINANT PROTEIN;

ALLERGY; CONFERENCE PAPER; GENETIC POLYMORPHISM; HUMAN; IMMUNOGLOBULIN PRODUCTION; IMMUNOTHERAPY; NONHUMAN; PEPTIDE ANALYSIS; POLYCLONAL ACTIVATION; PRIORITY JOURNAL; RECOMBINANT DNA TECHNOLOGY; SEQUENCE HOMOLOGY; T LYMPHOCYTE ACTIVATION;

EID: 0030437529     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-5855-2_12     Document Type: Conference Paper

References (78)

1. Thomas, W.R., G.A. Stewart, R.J. Simpson, K.Y. Chua, T.M. Plozza, R.J. Dilworth, A. Nisbet, and K.J. Turner. 1988. Cloning and expression of DNA coding for the major house dust mite allergen Der p I in Escherichia coli. Int Arch Allergy Appl Immunol. 85:127-9.
2. Chua, K.Y., G.A. Stewart, W.R. Thomas, R.J. Simpson, R.J. Dilworth, T.M. Plozza, and K.J. Turner. 1988. Sequence analysis of cDNA coding for a major house dust mite allergen, Der p I. Homology with cysteine proteases. J Exp Med. 167:175-82.
3. Fang, K.S.F., M. Vitale, P. Fehlner, and T.P. King. 1988. cDNA cloning and primary structure of a white-faced hornet venom allergen. Proc Natl Acad Sci. 85:895-899.
4. Seiberler, S., O. Scheiner, D. Kraft, D. Lonsdale, and R. Valenta. 1994. Characterization of a birch pollen allergen, Bet v III, representing a novel class of Ca2+ binding proteins: specific expression in mature pollen and dependence of patients' IgE binding on protein-bound Ca2+. EMBO. 13:3481-6.
5. Valenta, R., M. Duchene, K. Pettenburger, C. Sillaber, P. Valent, P. Bettelheim, M. Breitenbach, H. Rumpold, D. Kraft, and O. Scheiner. 1991. Identification of profilin as a novel pollen allergen; IgE-autoreactivity in sensitized individuals. Science. 253:557-58.
6. Breiteneder, H., K. Pettenburger, A. Bito, R. Valenta, D. Kraft, H. Rumpold, O. Scheiner, and M. Breitenbach. 1989. The gene coding for the major birch pollen allergen Bet v I, is highly homologous to a pea disease resistance response gene. Embo J. 8:1935-8.
7. Laffer, S., S. Vrtala, M. Duchene, R. van Ree, D. Kraft, O. Scheiner, and R. Valenta. 1994. IgE-binding capacity of recombinant timothy grass (Phleum pratense) pollen allergens. J Allergy Clin Immunol. 94:88-94.
8. Vrtala, S., W.R. Sperr, I. Reirnitzer, R. van Ree, S. Laffer, W.D. Muller, P. Valent, K. Lechner, H. Rumpold, and D. Kraft. 1993. cDNA cloning of a major allergen from timothy grass (Phleum pratense) pollen; characterization of the recombinant Ph1 pV allergen. J Immunol. 151:4773-81.
9. Singh, M.B., T. Hough, P. Theerakulpisut, A. Avjioglu, S. Davies, P.M. Smith, P. Taylor, R.J. Simpson, L.D. Ward, J. McCluskey, R. Puy, and R.B. Knox. 1991. Isolation of cDNA encoding a newly identified major allergenic protein of rye-grass pollen: Intracellular targeting to the amyloplast. Proc Natl Acad Sci USA. 88:1384-8.
10. Perez, M., G.Y. Ishioka, L.E. Walker, and R.W. Chesnut. 1990. cDNA cloning and immunological charaterisation of the rye grass allergen Lol p I. J. Biol. Chem. 265:16210-15.
11. Griffith, I.J., P.M. Smith, J. Pollock, P. Theerakulpisut, A. Avjioglu, S. Davis, T. Hough, M.B. Singh, R.J. Simpson, L.D. Ward, and R.B. Knox. 1991. Cloning and sequencing of Lol p I, the major allergenic protein of rye-grass pollen. FEBS Letters. 279:210-15.
12. Mohapatra, S.S., R. Hill, J. Astwood, A.K. Ekramoddoullah, E. Olsen, A. Silvanovitch, T. Hatton, F.T. Kisil, and A.H. Schon. 1990. Isolation and characterization of a cDNA clone encoding an IgE-binding protein from Kentucky bluegrass (Poa pratensis) pollen. Int Arch Allergy Appl Immunol. 91:362-8.
13. Silvanovitch, A., J. Astwood, L. Zang, E. Olsen, F. Kisil, A. Sehon, S.S. Mohapatra, and R.D. Hill. 1991. Nucleotide sequence analysis of three Poa p IX isoallergens of Kentucky bluegrass pollen. J. Biol. Chem. 266:1204-10.
14. Morgenstern, J.P., I.J. Griffith, A.W. Brauer, B.L. Rogers, J.F. Bond, M.D. Chapman, and M.C. Kuo. 1991. Amino acid sequence of Fel d I, the major allergen of the domestic cat: Protein sequence analysis and cDNA cloning. Poc Natl Acad Sci USA. 88:9690-94.
15. Rafnar, T., I.J. Griffith, M. Kuo, J.F. Bond, B.L. Rogers, and D.G. Klapper. 1991. Cloning of Amb a I (Antigen E), the major allergen family of short Ragweed pollen. J Biol Chem. 266:1229-36.
16. Rogers, B.L., J.P. Morgenstern, I.J. Griffith, X. Yu, C.M. Counsell, A.W. Brauer, T.P. King, R.D. Garman, and M. Kuo. 1991. Complete sequence of the allergen Amb a II. Recombinant expression and reactivity with T cells from Ragweed allergic patients. J Immunol. 147:2547-52.
17. Ghosh, B., M.P. Perry, and D.G. Marsh. 1991. Cloning the cDNA encoding the Amb t V allergen from giant ragweed (Ambrosia tridida). Gene. 101:231-8.
18. Chapman, M.D. 1993. Dissecting cockroach allergens. Clin Exp Allergy. 23:459-61.
19. Vijay, H.M., in Recent Trends in Aerobiology, Allergy and Immunology S.N. Agashe, Eds. (Oxford and IBH Publishing Co, New Dehli, 1994) pp. 247-77.
20. King, T.P., D. Hoffman, H. Løwenstein, D.G. Marsh, T.A.E. Platts-Mills, and W.R. Thomas. 1994. Allergen nomenclature. Int Arch Allergy Immunol. 105:224-233.
21. Aki, T., K. Ono, P. Soon-Young, T. Wada, T. Jyo, S. Shigeta, Y. Murooka, and S. Oka. 1994. Cloning and characterization of cDNA coding for a new allergen from the house dust mite, Dermatophagoides farinae. Int Arch Allergy Immunol. 103:349-56.
22. Aki, T., A. Fujikawa, T. Wada, T. Jyo, S. Shigeta, Y. Murooka, S. Oka, and K. Ono. 1994. Cloning and expression of cDNA coding for a new allergen from the house dust mite, Dermatophagoides farinae: homology with human heat shock cognate proteins in the heat shock protein 70 family. J Biochem. 115:435-40.
23. O'Neill, G., G.R. Donovan, and B.A. Baldo. 1994. Identification of a major allergen of the house dust mite, Dermatophagoides pteronyssinus, homologous with glutathione-S-transferase. Biochim Biophys Acta. 1219:521-524.
24. Bousquet, J. 1994. Specific immunotherapy in asthma: Is it effective? J Allergy Clin Immunol. 94:1-11.
25. Norman, P.S. 1980. An overview of immunotherapy: Implications for the future. J Allergy Clin Immunol. 65:87-96.
26. Ipsen, H., and H. Løwenstein. 1983. Isolation and immunochemical charaterisation of the major allergen of birch pollen (Betula verrucosa). J Allergy Clin Immunol. 72:150-159.
27. Schou, C. 1993. Defining allergens of mammalian origin. Clin Exp Allergy. 23:7-14.
28. King, T.P. 1976. Chemical and biological properties of atopic allergens. Adv Immunol. 23:77-105.
29. 1. J Immunol. 125:587-92.
30. Van der Zee, J.S., P. van Swieten, H.M. Jansen, and R.C. Aalberse. 1988. Skin tests and histamine release with P1-depleted Dermatophagoides pteronyssinus body extracts and purified P1. J Allergy Clin Immunol. 81:884-95.
31. Meyer, C.H., J.F. Bond, M. Chen, and M.T. Kasaian. 1994. Comparison of the levels of the major allergens Der p I and Der p II in standardised extract of the house dust mite, Dermatophagoides pteronyssinus. Clin Exp Allergy. 24:1041-48.
32. Smith, P.M., M.B. Singh, and R.B. Knox, in Molecular biology and immunology of allergens D. Kraft, A. Sehon, Eds. (CRC Press, Boca Raton, 1993) pp. 157-160.
33. Stewart, G.A., L.D. Ward, R.J. Simpson, and P.J. Thompson. 1992. The group III allergen from the house dust mite Dermatophagoides pteronyssinus is a trypsin-like enzyme. Immunology. 75:29-35.
34. Tovey, E.R., M.C. Johnson, A.L. Roche, G.S. Cobon, and B.A. Baldo. 1989. Cloning and sequencing of a cDNA expressing a recombinant house dust mite protein that binds human IgE and corresponds to an important low molecular weight allergen published erratum appears in J Exp Med 1990 Apr 1;171(4):1387:. J Exp Med. 170:1457-62.
35. Lin, K.L., K.Y. Chua, W.R. Thomas, B.L. Chiang, and K.H. Hsieh. 1994. Characterisation of Der p V allergen. cDNA analysis and IgE-mediated reactivity to the recombinant protein. J Allergy Clin Immunol. 94:989-996.
36. Shen, H.D., K.Y. Chua, K.L. Lin, K.H. Hsieh, and W.R. Thomas. 1993. Molecular cloning of a house dust mite allergen with common antibody binding specificities with multiple components in mite extracts. Clin Exp Allergy. 23:934-40.
37. Tovey, E.R., and B.A. Baldo. 1987. Comparison by electroblotting of IgE-binding components in extracts of house dust mite bodies and spent mite culture. J Allergy Clin Immunol. 79:93-102.
38. Shibasaki, M., S. Isoyama, and H. Takita. 1994. Influence of age on IgE responsiveness to Dermatophagoides farinae: An immunoblot study. Int Arch Allergy Immunol. 103:53-58.
39. O'Brien, R.M., and W.R. Thomas. 1994. Immune reactivity to Der p I and Der p II in house dust mite sensitive patients attending paediatric and adult allergy clinics. Clin Exp Allergy. 24:737-42.
40. Miller, A., O. Lider, and H.L. Weiner. 1991. Antigen-driven bystander suppression after oral administration of antigens. J Exp Med. 174:791-98.
41. Briner, T.J., M.C. Kuo, K.M. Keating, B.L. Rogers, and J.L. Greenstein. 1993. Peripheral T cell tolerance reduced in naive and primed mice by subcutaneous injection of peptides from the major□ cat allergen, Fel d I. Proc Nat Acad Sci. 90:7609-12.
42. Hoyne, G.F., R.E. O'Hehir, D.C. Wraith, W.R. Thomas, and J.R. Lamb. 1993. Inhibition of T-cell and antibody responses to house dust mite allergen by inhalation or the dominant epitope in naive and sensitised mice. J Exp Med. 178:1783-88.
43. Hoyne, G.F., Callow, M.G., Kuo, M-C. & Thomas, W.R. 1994. Inhibition of T-cell responses by feeding peptides containing major and cryptic epitopes: studies with the Der p I allergen. Immunology: 83:190-95.
44. Osterballe, O. 1982. Immunotherapy with grass pollen major allergens. Clinical results from a prospective 3-year double blind study. Allergy. 37:379-388.
45. Norman, P.S., W.L. Winkenwerder, and L.M. Lichtenstein. 1968. Immunotherapy of hayfever with ragweed antigen E: Comparison with whole pollen extract and placebos. J Allergy. 42:93-108.
46. Greene, W.K., J.G. Cyster, K.Y. Chua, R.M. O'Brien, and W.R. Thomas. 1991. IgE and IgG binding of peptides expressed from fragments of cDNA encoding the major house dust mite allergen Der p I. J Immunol. 147:3768-73.
47. Chua, K.Y., W.K. Greene, P. Kehal, and W.R. Thomas. 1991. IgE binding studies with large peptides expressed from Der p II cDNA constructs. Clin Exp Allergy. 21:161-166.
48. Van't Hof, W., P.C. Driedijk, M. Van den Berg, A.G. Beck-Sickinger, G. Jung, and R.C. Aalberse. 1991. Epitope mapping of the Dermatophagoides pteronyssinus house dust mite major allergen Der p II using overlapping synthetic peptides. Mol Immunol. 28:1225-32.
49. Rogers, B.L., J.L. Bond, S.J. Craig, A.K. Nault, D.B. Segal, J.P. Morgenstern, M. Chen, C.B. Bizinkauskas, C.M. Counsell, A.M. Lussier, T. Luby, M. Kuo, T.J. Briner, and R.D. Garman. 1994. Potential therapeutic recombinant proteins comprised of peptides containing recombined T cell epitoopes. Mol Immunol. 31:955-66.
50. O'Hehir, R.E., A. Verhoef, E. Panagiotopoulou, S. Keswani, J.D. Hayball, W.R. Thomas, and J.R. Lamb. 1993. Analysis of human T cell responses to the group II allergen of Dermatophagoides species : Localisation of major antigenic sites. J Allergy Clin Immunol. 92:105-33.
51. Yssel, H., K.E. Johnson, P.V. Schneider, J. Wideman, A. Terr, R. Kastelein, and J.E. De Vries. 1992. T cell activation-inducing epitopes of the house dust mite allergen Der p I. Proliferation and lymphokine production patterns by Der p I-specific CD4+ T cell clones. J Immunol. 148:738-45.
52. O'Hehir, R.E., G.F. Hoyne, W.R. Thomas, and J.R. Lamb. 1993. House dust mite allergy:from T cell epitopes to immunotherapy. Europ J Clin Invest. 23:763-72.
53. Higgins, J.E., C.J. Thorpe, R.E. Hayball, J.R.J.D. Lamb, and O'Hehir. 1994. Overlapping T-cell epiopes in the group I allergen of Dermatophagoides species restricted by HLA-DP and HLA-DR class II molecules. J Allergy Clin Immunol. 93:891-99.
54. Upham, J.W., B.J. Holt, M.J. Baron-Hay, A. Yabuhara, B.J. Hales, W.R. Thomas, R.K.S. Loh, P. O'Keefe, L. Palmer, P. Le Souef, P.D. Sly, P.R. Burton, B.W.S. Robinson, and P.G. Holt. 1995. Allergen-specific T-cell reactivity is detecable in close to 100% of atopic and normal individuals: covert responses are unmasked by serum-free medium. Clun Exp Allergy.
55. O'Brien, R.M., W.R. Thomas, and A.M. Wootton. 1992. T cell responses to the purified major allergens from the house dust mite Dermatophagoides pteronyssinus. J Allergy Clin Immunol. 89:1021-31.
56. Rawle, F.C., E.B. Mitchell, and T.A.E. Platts-Mills. 1984. T-cell response to the major allergen from the house dust mite, Dermatophagoides pteronyssinus, antigen P1: comparison of patients with asthma, atopic dermatitis and perennial rhinitis. J Immunol. 133:195-201.
57. Thomas, W.R., and K.Y. Chua, in Molecular Biology and Immunology of Allergens D. Kraft, Eds. (CRC Press, Boca Raton, 1992) pp. 21-29.
58. Topham, C.M., N. Srinivasan, C.J. Thorpe, H. Overington, and N.A. Kalsheker. 1994. Comparative modelling of major house dust mite allergen Der p I: structure validation using an extended environmental amino acid propensity table. Protein Engineering. 7:869-94.
59. Greene, W.K., K.Y. Chua, G.A. Stewart, and W.R. Thomas. 1990. Antigenic analysis of group I house dust mite allergens using random fragments of Der p I expressed by recombinant DNA libraries. Int Arch Allergy Appl Immunol. 92:30-8.
60. Dilworth, R.J., K.Y. Chua, and W.R. Thomas. 1991. Sequence analysis of cDNA coding for a major house dust mite allergen, Der f I. Clin Exp Allergy. 21:25-32.
61. Kent, N.A., M.R. Hill, J.N. Keen, P.W.H. Holland, and B.J. Hart. 1992. Molecular characterisation of group I allergen Eur m I from house dust mite Euroglyphus maynei. Int Arch Allergy Appl Immunol. 99:150-152.
62. Kemeny, D.M., and D. Diaz-Sanchez. 1993. The role of CD8+ T cells in the regulation of IgE. Clin Exp Allergy. 23:466-470.
63. McMenamin, C., and P.G. Holt. 1993. The natural immune response to inhaled soluble protein antigens involves major histocompatibility (MHC) class I resticted CD8+ T cell mediated butMHC class II dependent immune deviation resulting in selective suppression of immunoglobulain E production. J Exp Med. 178:889-99.
64. Renz, H., G. Lack, J. Saloga, R. Schwinzer, K. Bradley, J. Loader, A. Kupfer, G.L. Larsen, and E.W. Gelfand. 1994. Inhibition of IgE production and normaalisation of airways responsiveness by sensitized CD8 T cells in a mouse model of allergen sensitization. J Immunol. 152.
65. McMenamin, C., C. Pim, M. McKellar, and P.G. Holt. 1994. Regulation of IgE responses to inhaled antigen by antigen specific gamma delta T cells. Science. 265:1869-71.
66. Hoyne, G.F., M.G. Callow, M.-C. Kuo, and W.R. Thomas. 1993. Characterisation of T cell responses to the house dust mite allergen Der p II in mice. Evidence for major and cryptic epitopes. Immunology. 78:65-73.
67. Higgins, P.J., and H.L. Weiner. 1988. Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin basic protein and its fragments. J. Immunol. 144:441-45.
68. Griffith, I.J., J. Pollock, D.G. Klapper, B.L. Rogers, and A.K. Nault. 1991. Sequence polymorphism of Amb a I and Amb a II, the major allergens in Ambrosia artemisiifolia (Short Ragweed). Int Arch Allergy Appl Immunol. 96:296-304.
69. Laemmli, U.K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:680-82.
70. Larsen, J.N., P. Stroman, and H. Ipsen. 1992. PCR based cloning and sequencing of isogenes encoding the tree pollen major allergen Car b I from Carpinus betulis, Hornbeam. Mol Immunol. 29:703-11.
71. Breiteneder, H., F. Ferreira, K. Hoffmann-Sommergruber, C. Ebner, M. Breitenbach, H. Rumpold, D. Kraft, and O. Scheiner. 1993. Four recombinant isoforms of Cor a I, the major allergen of hazel pollen, show different IgE-binding properties. Eur J Biochem. 212:355-62.
72. Griffith, I.J., S. Craig, J. Pollock, X. Yu, J.P. Morgenstern, and B.L. Rogers. 1992. Expression and genomic structure of the genes encoding Fel d I, the major allergen from the domestic cat. Gene. 113:263-68.
73. Chua, K.Y., P.K. Kehal, and W.R. Thomas. 1993. Sequence polymorphisms of cDNA clones encoding the mite allergen Der p I. Int Arch Allergy Appl Immunol. 101:364-68.
74. Thomas, W.R., K.Y. Chua, and W.A. Smith. 1992. Molecular polymorphisms of house dust mite allergens. Exp Appl Acarology. 16:153-64.
75. Yuuki, T., Y. Okumura, T. Ando, H. Yamakawa, M. Suko, M. Haida, and H. Okudaira. 1990. Cloning and sequencing of cDNAs corresponding to mite major allergen Der f II. Arerugi. 39:557-61.
76. Nishiyama, C., T. Yuuki, Y. Usui, N. Iwamoto, Y. Okumura, and H. Okudaira. 1994. Effects of amino acid variations in recombinant Der f II on its human IgE and mouse IgG recognition. Int Arch Allergy Immunol. 105:62-9.
77. Trudinger, M., K.Y. Chua, and W.R. Thomas. 1991. cDNA encoding the major mite allergen Der f II. Clin Exp Allergy. 21:33-7.
78. Colloff, M.J., G.A. Stewart, and P.J. Thompson. 1991. House dust mite acarofauna and Der p I equivalent in Australia: the relative importance of Dermatophagoides pteronyssinus and Euroglyphus maynei. Clin Exp Allergy. 21:225-30.