Liposomal amphotericin B as early empiric antimycotic therapy of pneumonia in granulocytopenic patients

Mycoses

Volumn 39, Issue 11-12, 1996, Pages 419-426

  Böhme, Angelika ^a,b   Hoelzer, D ^a  

^a GOETHE UNIVERSITY   (Germany)

^b Med Klinik III/Infektiologie   (Germany)

Author keywords

AmBisome ; Amphotericin B; Aspergillosis; Liposomal preparation; Neutropenia; Pneumonia

Indexed keywords

AMPHOTERICIN B; AMPHOTERICIN B LIPID COMPLEX; ANTIBIOTIC AGENT; LIPOSOME;

ADULT; AGED; ARTICLE; ASPERGILLOSIS; ASPERGILLUS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG TOLERANCE; FEMALE; HUMAN; MALE; NEUTROPENIA; PNEUMONIA; PRIORITY JOURNAL;

ASPERGILLUS;

EID: 0030436738     PISSN: 09337407     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1439-0507.1996.tb00090.x     Document Type: Article

References (40)

1. Bodey, G. P., Bueltmann, B., Duguid, W. et al. (1992) Fungal infections in cancer patients: an international autopsy survey. Eur. J. Clin. Microbiol. Infect. Dis. 11, 99-109.
2. Meyers, J. D. (1990) Fungal infections in bone marrow transplant patients. Semin. Oncol. 17 (Suppl. 6), 10-13.
3. Saral, R. (1991) Candida and Aspergillus in immunocompromised patients: an overview. Rev. Inject. Dis. 13, 487-492.
4. Bodey, G. P. & Vartivarian, S. (1989) Aspergillosis. Eur. J. Clin. Microbiol. Infect. Dis. 8, 413-437.
5. Pannuti, C. S., Gingrich, R. D., Pfaller, M. & Wenzel, R. P. (1991) Nosocomial pneumonia in adult patients undergoing bone marrow transplantation: a 9 year study. J. Clin. Oncol. 9, 77-84.
6. Rinaldi, M. G. (1991) Problems in the diagnosis of invasive fungal diseases. Rev. Infect. Dis. 13, 493-495.
7. Rüchel, R. (1993) Diagnosis of invasive mycoses in severely immunosuppressed patients. Ann. Hematol. 67, 1-11.
8. Aisner, J., Schimpff, S. C. & Wiernik, P. H. (1977) Treatment of invasive aspergillosis: relation of early diagnosis and treatment to response. Ann. Int. Med. 86, 539-543.
9. Burch, P. A., Karp, J. E., Merz, W. G., Kuhlman, J. E. & Fishman, E. K. (1987) Favorable outcome of invasive aspergillosis in patients with acute leukemia. J. Clin. Oncol. 5, 1985-1993.
10. Böhme, A., Just-Nübling, G., Bergmann, L., Shah, P. M., Stille, W. & Hoelzer, D. (1995) A randomized study of imipenem compared to cefotaxime plus piperacillin as initial therapy of infections in granulocytopenic patients. Infection 23, 349-355.
11. Maschmeyer, G., Link, H. & Hiddemann, W. (1994) Pulmonary infiltrations in febrile patients with neutropenia. Cancer 73, 2296-2304.
12. Wegmann, T. (1989) Antimykotika. Der Internist 30, 46-50.
13. DeGregorio, M. W., Lee, W. M., Linker, C. A., Jacobs, R. A. & Ries, C. A. (1982) Fungal infections in patients with acute leukemia. Am. J. Med. 73, 543-548.
14. Arning, M. & Scharf, R. E. (1989) Prevention of amphotericin B-induced nephrotoxicity by loading with sodium chloride: a report of 1291 days of treatment with amphotericin B without renal failure. Klin. Wochenschrift 67, 1020-1028.
15. Wasan, K. M., Vadiel, K., Lopez-Berestein, G., Verani, L. & Luke, D. R. (1990) Pentoxifylline in amphotericin B toxicity rat model. Antimicrob. Agents Chemother. 34, 241-244.
16. Moreau, P., Milpied, N., Fayette, N., Ramee, J.-F. & Harousseau, J.-L. (1992) Reduced renal toxicity and improved clinical tolerance of amphotericin B mixed with Intralipid compared with conventional amphotericin B in neutropenic patients. J. Antimicrob. Chemother. 30, 535-541.
17. Ranchere, J. Y., Latour, J. F., Fuhrmann, C. & Loreuil, F. (1996) Amphotericin B intralipid formulation: stability and particle size. J. Antimicrob. Chemother. 37, 1165-1169.
18. Trissel, L. A. (1995) Amphotericin B does not mix with fat emulsion. Am. J. Health-Syst. Pharm. 52, 1463-1464.
19. Stevens, D. A. (1994) Overview of amphotericin B colloidal dispersion (Amphocil®). J. Infect. 28 (Suppl.), 45-49.
20. Walker, R. C. (1995) Renal-sparing effects of amphotericin B lipid complex in life-threatening mycoses. Can. J. Infect. Dis. 6 (Suppl. C), abstract no. 0633 286C.
21. Mills, W., Chopra, R., Linch, D. C. & Goldstone, A. H. (1994) Liposomal amphotericin B in the treatment of fungal infections in neutropenic patients: a single centre experience of 133 episodes in 116 patients. Br. J. Haematol. 86, 754-760.
22. Krüger, W., Stockschläder, M. & Rüssmann, B. (1995) Experience with liposomal amphotericin B in 60 patients undergoing high-dose therapy and bone marrow or peripheral blood stem cell transplantation. Br. J. Haematol. 91, 684-690.
23. Ringden, O., Meunier, F. & Tollemar, J. (1991) Efficacy of amphotericin B encapsulated in liposomes (AmBisome) in the treatment of invasive fungal infections in immunocompromised patients. J. Antimicrob. Chemother. 28 (Suppl.), 73-82.
24. Emminger, W., Graninger, W., Emminger-Schmidmeier, W. et al. (1994) Tolerances of high doses of amphotericin B by infusion of a liposomal formulation in children with cancer. Ann. Hematol. 68, 27-31.
25. Leslie, J., Innes, A. J., Helfinger, R. & Barker, T. (1993) Successful treatment of rhinomaxillary mucormycosis with high dose liposomal amphotericin B (AmBisome), XIIth Meeting of the International Society of Haematology (European and African Division), Vienna, Aug 28-Sep 3, 1993, abstract no. 585.
26. Proffitt, R. T., Satorius, A., Chiang, S.-M., Sullivan, L. & Adler-Moore, J. P. (1991) Pharmacology and toxicology of a liposomal formulation of amphotericin B (AmBisome) in rodents. J. Antimicrob. Chemother. 28 (Suppl. B), 49-61.
27. Heinemann, V., Forst, H. & Jehn, U. (1994) Enhanced pulmonary accumulation of liposomal amphotericin B (AmBisome) in acute liver transplant failure. Onkologie 17 (Suppl.), abstract no. 229.
28. Böhme, A. & Hoelzer, D. (1994) Liposomales Amphotericin B (AmBisome®) in der Therapie von pulmonalen Infiltraten bei granulozytopenischen Patienten. Bettelheim, P., Emminger, W. & Gladner, H. (eds) 28. Wissenschaftl. Tagung Deutschspr. Mykolog. Gesellschaft, Montreux, Wien: Robidruck, abstract no. P 28.
29. Kuhlman, J. E., Fishman, E. K., Burch, P. A., Karp, J. E., Zerhouni, E. A. & Siegelman, S. S. (1987) Invasive pulmonary aspergillosis in acute leukemia: the contribution of CT to early diagnosis and aggressive management. Chest 92, 95-99.
30. Orr, D. P., Myerowitz, R. L. & Dubois, P. J. (1978) Patho-radiologic correlation of invasive pulmonary aspergillosis in the compromised host. Cancer 41, 2028-2039.
31. Roos, N., Fahrenkamp, A., v. Eiff, M., Diederich, S., Boemmelburg, T., Ritter, J. et al. (1991) Diagnostic value of radiologic imaging methods in detection and follow-up of invasive pulmonary aspergillosis. Mycoses 34 (Suppl.), 37-41.
32. Robertson, M. J. & Larson, R. A. (1988) Recurrent fungal pneumonias in patients with acute nonlymphocytic leukemia undergoing multiple courses of intensive chemotherapy. Am. J. Med. 84, 233-239.
33. Silling-Engelhardt, G., Zühlsdorf, M., Aguion-Freire-Innig, E., Griesinger, F., Büchner, T. & van de Loo, J. (1992) Efficacy of liposomal amphotericin B (AmBisome) in neutropenic patients with fungal infection (abstract). Ann. Hematol. 64 (Suppl.), abstract no. 150.
34. Karp, J. E., Merz, W. G. & Charache, P. (1991) Response to empiric amphotericin B during antileukemic therapy-induced granulocytopenia. Rev. Inject. Dis. 13, 592-599.
35. Sugar, A. M. (1990) Empiric treatment of fungal infections in the neutropenic host. Arch. Int. Med. 150, 2258-2264.
36. Pizzo, P. A. (1993) Management of fever in patients with cancer and treatment-induced neutropenia. N. Engl. J. Med. 328, 1323-1332.
37. Arning, M., Heer-Sonderhoff, A. H., Wehmeier, A. & Schneider, W. (1995) Pulmonary toxicity during infusion of liposomal amphotericin B in two patients with acute leukemia. Eur. J. Microbiol. Infect. Dis. 14, 41-43.
38. Prentice, H. G., Catovsky, D., Aoun, M. et al. (1995) AmBisome versus amphotericin B in patients with fever unresponsive to antibiotic therapy for 96 hours, or with confirmed fungal infection. Klastersky, J. (ed.) 2nd International Symposium on Febrile Neutropenia, Waterloo: Vase Frères, Brussels, abstract no. 35.
39. Hahn, U., Deboben, A., Egerer, G., Goldschmidt, H., Haas, R. & Hunstein, W. (1992) Liposomal amphotericin B (AmBisome®) in patients with severe neutropenia and antibiotic resistant fever (abstract). Ann. Hematol. 64 (Suppl.), abstract no. 149.
40. Ritter, J., Ahlke, E., Boos, J. & Jürgens, H. (1995) Prophylactic use of liposomal amphotericin B (AmBisome) in neutropenic children with hematological malignancies and high risk for invasive fungal infection. Onkologie 18 (Suppl. 2), abstract no. 690.