Pharmacological evidence for tumor necrosis factor as a mediator of allergic inflammation in the airways

Journal of Pharmacology and Experimental Therapeutics

Volumn 278, Issue 2, 1996, Pages 847-853

  Renzetti, Louis M ^a   Paciorek, Peter M ^a   Tannu, Shahid A ^a   Rinaldi, Nancy C ^a   Tocker, Joel E ^a   Wasserman, Martin A ^a   Gater, Paul R ^a  

^a HOFFMANN LA ROCHE INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; DEXAMETHASONE; HYBRID PROTEIN; LENERCEPT; OVALBUMIN; SUBSTANCE P; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG;

AIRWAY; ALLERGIC REACTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; GUINEA PIG; INFLAMMATION; INFLAMMATORY INFILTRATE; INTRAPERITONEAL DRUG ADMINISTRATION; LUNG LAVAGE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SENSITIZATION;

ANIMALS; DEXAMETHASONE; DOSE-RESPONSE RELATIONSHIP, DRUG; GUINEA PIGS; INFLAMMATION MEDIATORS; MALE; RATS; RESPIRATORY SYSTEM; SUBSTANCE P; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030434267     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. ACKERMAN, V., MARINI, M., VITTORI, E., BELLINI, A., VASSALI, G. AND MATTOLI, S.: Detection of cytokines and their cell sources in bronchial biopsy specimens from asthmatic patients. Relationship to atopic status, symptoms, and level of airway hyperresponsiveness. Chest 105: 687-696, 1994.
2. AMDUR, M. O. AND MEAD, J.: Mechanics of respiration in unanesthetized guinea pigs. Am. J. Physiol. 192: 364-372, 1958.
3. AMRANI, Y., MARTINET, N. AND BRONNER, C.: Potentiation by tumour necrosis factor-alpha of calcium signals induced by bradykinin and carbachol in human tracheal smooth muscle. Br. J. Pharmacol. 114: 4-5, 1995.
4. ANDERSON, J. A., MILLER, F. N., SIMS, D. E. AND EDWARDS, M. J.: Tumor necrosis factor causes microvascular protein leakage independently of neutrophils or mast cells. J. Surg. Res. 56: 485-490, 1994.
5. ASHKENAZI, A., MARSTERS, S. A., CAPON, D. J., CHAMOW, S. M., FIGARI, I. S., PENNICA, D., GOEDDEL, D. V., PALLADINO, M. A. AND SMITH, D. H.: Protection against endotoxic shock by a tumor necrosis factor receptor immunoadhesin. Proc. Natl. Acad. Sci. 88: 10535-10539, 1991.
6. BLOEMEN, P. G., VAN DEN TWEEL, M. C., HENRICKS, P. A., ENGELS, F., WAGENAAF, S. S., RUTTEN, A. A. AND NIJKAMP, F. P.: Expression and modulation of adhesion molecules on human bronchial epithelial cells. Am. J. Respir. Cell Mol. Biol. 9: 586-593, 1993.
7. BOSCHETTO, P., ROGERS, D. F., FABRI, L. M. AND BARNES, P. J.: Coritcosteroid inhibition of airway microvascular leakage. Am. Rev. Respir. Dis. 143: 605-609, 1991.
8. BRADDING, P., ROBERTS, J. A., BRITTEN, K. M., MONTEFORT, S., DJUKANOVIC, R., MUELLER, R., HEUSSER, C. H., HOWARTH, P. H. AND HOLGATE, S. T.: Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines. Am. J. Respir. Cell Mol. Biol. 10: 471-480, 1994.
9. BROIDE, D. H., LOTZ, M., CUOMO, A. J., COBURN, D. A., FEDERMAN, E. C. AND WASSERMAN, S. I.: Cytokines in symptomatic asthma airways. J. Allergy Clin. Immunol. 89: 958-967, 1992.
10. CEMBRZYNSKA-NOWAK, M., SZKLARZ, E., INGLOT, A. D. AND TEODORCZYK-INJEYAN, J. A.: Elevated release of tumor necrosis factor-alpha and interferon-gamma by bronchoalveolar leukocytes from patients with bronchial asthma. Am. Rev. Respir. Dis. 147: 291-295, 1993.
11. COSTA, J. J., MATOSSIAN, K, RESNICK, M. B., BEIL, W. J., WONG, D. T., GORDON, J. R., DVORAK, A. M., WELLER, P. F. AND GALLI, S. J.: Human eosinophils can express the cytokines tumor necrosis factor-alpha and macrophage inflammatory protein-1 alpha. J. Clin. Invest. 91: 2673-2684, 1993.
12. CROMWELL, O., HAMID, Q., CORRIGAN, C. J., BARKANS, J., MENG, Q., COLLINS, P. D. AND KAY, A. B.: Expression and generation of interleukin-8, IL-6 and granulocyte-macrophage colony-stimulating factor by bronchial epithelial cells and enhancement by IL-1b and tumour necrosis factor-α. Immunology 77: 330-337, 1992.
13. DEVALIA, J. L., CAMPBELL, A. M., SAPSFORD, R. J., RUSZNAK, C., QUINT, D., GODARD, P., BOUSQUET, J. AND DAVIES, R. J.: Effect of nitrogen dioxide on synthesis of inflammatory cytokines expressed by human bronchial epithelial cells in vitro. Am. J. Respir. Cell Mol. Biol. 9: 271-278, 1993.
14. ELWOOD, W., LOTVALL, J. O., BARNES, P. J. AND CHUNG, K. F.; Effect of dexamethasone and cyclosporin A on allergen-induced airway hyperresponsiveness and inflammatory cell responses in sensitized Brown-Norway rats. Am. Rev. Respir. Dis. 145: 1289-1294, 1992.
15. FINOTTO, S., OHNO, I., MARSHALL, J. S., GAULDIE, J., DENBURG, J. A., DOLOVICH, J., CLARK, D. A. AND JORDANA, M.: TNF-alpha production by eosinophils in upper airways inflammation (nasal polyposis). Immunology 153: 2278-2289, 1994.
16. FISCHER, B. M., KRUNKOSKY, T. M., WRIGHT, D. T., DOLAN-O'KEEFE, M. AND ADLER, K. B.: Tumor necrosis factor-alpha [TNF-α] stimulates mucin secretion and gene expression in airway epithelium in vitro. Chest 107: 133S-135S, 1995.
17. GATER, P. R., WASSERMAN, M. A., PACIOREK, P. M. AND RENZETTI, L. M.: Inhibition of Sephadex-induced lung injury in the rat by Ro 45-2081, a tumor necrosis factor receptor fusion protein. Am. J. Respir. Cell Mol. Biol. 14: 454-460, 1996.
18. GORDON, J. R. AND GALLI, S. J.: Mast cells as a source of both preformed and immunologically inducible TNF-a/cachectin. Nature (Lond.), 346: 274-276, 1990.
19. GOSSET, P., TSICOPOULOS, A., WALLAERT, B., VANNIMENUS, C., JOSEPH, M., TONNEL, A. B. AND CAPRON, A.: Increased secretion of tumor necrosis factor alpha and interleukin-6 by alveolar macrophages consecutive to the development of the late asthmatic reaction. J. Allergy Clin. Immunol. 88: 561-571, 1991.
20. GOSSET, P., TSICOPOULOS, A., WALLAERT, B., JOSEPH, M., CAPRON, A. AND TONNEL, A. B.: Tumor necrosis factor alpha and interleukin-6 production by human mononuclear phagocytes from allergic asthmatics after IgE-dependent stimulation. Am. Rev. Respir. Dis. 146: 768-774, 1992.
21. GUNDEL, R. H., WEGNER, C. D., TORCELLINI, C. A. AND LETTS, L. G.: The role of intracellular adhesion molecule-1 in chronic airway inflammation. Clin. Exp. Allergy 22: 569-574, 1992.
22. KIPS, J. C., TAVERNIER, J. AND PAUWELS, R. A.: Tumor necrosis factor causes bronchial hyperresponsiveness in rats. Am. Rev. Respir. Dis. 145: 332-336, 1992.
23. KWON, O. J., AU, B. T., COLLINS, P. D., ADCOCK, I. M., MAK, J. C., ROBBINS, R. R., CHUNG, K. F. AND BARNES, P. J.: Tumor necrosis factor-induced interleukin-8 expression in cultured human airway epithelial cells. Am. J. Physiol. 267: L398-L405, 1994.
24. LESSLAUER, W., TABUCHI, H., REINER, G., BBOCKHAUS, M., SCHLAEGER, E. J., GRAU, G., PIGUET, P. F., POINTAIRE, P., VASSALLI, P. AND LOETSCHER, H.: Recombinant soluble tumor necrosis factor receptor proteins protect mice from lipopolysaccharide-induced lethality. Eur. J. Immunol. 21: 2883-2886, 1991.
25. LEVINE, S. J., LARIVEE, P., LOGUN, C., ANGUS, C. W., OGNIBENE, F. P. AND SHELHAMER, J. H.: Tumor necrosis factor-α induces mucin hypersecretion and MUC-2 gene expression by human airway epithelial cells. Am. J. Respir. Cell Mol. Biol. 12: 196-204, 1995.
26. LI, X. Y., DONALDSON, K., BROWN, D. AND MACNEE, W.: The role of tumor necrosis factor in increased airspace epithelial permeability in acute lung inflammation. Am. J. Respir. Cell Mol. Biol. 13: 185-195, 1995.
27. LOETSCHER, H., GRENTZ, R., ZULAUF, M., LUSTIG, A., TABUCHI, H., SCHLAERGER, E. J., BROCKHAUS, M., GALLATI, H., MANNEBERG, M. AND LESSLAUER, W.: Recombinant 55-kDa tumor necrosis factor receptor: Stoichiometry of binding to TNFα and TNFβ and inhibition of TNF activity. J. Biol. Chem. 266: 18324-18329, 1991.
28. LUKACS, N. W., STRIETER, R. M., CHENSUE, S. W., WIDMER, M. AND KUNKEL, S. L.: TNF-alpha mediates recruitment of neutrophils and eosinophils during airway inflammation. J. Immunol. 154: 5411-5417, 1995.
29. MATSUMOTO, T., ASHIDA, Y. AND TSUKUDA, R.: Pharmacological modulation of immediate and late airway response and leukocyte infiltration in the guinea pig. J. Pharmacol. Exp. Ther. 269: 1236-1244, 1994.
30. MYATT, N., COOHILL, G., MORRISON, K., JONES, D. AND CREE, I. A.: Detection of tumour necrosis factor alpha in sarcoidosis and tuberculosis granulomas using in situ hybridisation. J. Clin. Pathol. 47: 423-426, 1994.
31. NASH, J. R., MCLAUGHLIN, P. J., HOYLE, C. AND ROBERTS, D.: Immunolocalization of tumour necrosis factor alpha in lung tissue from patients dying with adult respiratory distress syndrome. Histopathology 19: 395-402, 1991.
32. O'DONNELL, M., GARIPPA, R. J., RINALDI, N., SELIG, W. M., SIMKO, B., RENZETTI, L., TANNU, S. A., WASSERMAN, M. A., WELTON, A. AND BOLIN, D. R.: Ro 25-1553: a novel, long-acting vasoactive intestinal peptide agonist. Part I: In vitro and in vivo bronchodilator studies. J. Pharmacol. Exp. Ther. 270: 1282-1288, 1994.
33. OHKAWARA, Y., YAMAUCHI, K., TANNO, Y., TAMURA, G., OHTANI, H., NAGURA, H., OHKUDA, K. AND TAKISHIMA, T.: Human lung mast cells and pulmonary macrophages produce tumor necrosis factor-alpha in sensitized lung tissue after IgE receptor triggering. Am. J. Respir. Cell Mol. Biol. 7: 385-392, 1992.
34. PILEWSKI, J. M., PANETTIERI, R. A., JR., KAISER, L. R. AND ALBELDA, S. M.: Expression of endothelial cell adhesion molecules in human bronchial xenografts. Am. J. Respir. Crit. Care Med. 150: 795-801, 1994.
35. ROBINSON, D., HAMID, Q., YING, S., BENTLEY, A., ASSOUFI, B., DURHAM, S. AND KAY, A. B.: Prednisolone treatment in asthma is associated with modulation of bronchoalveolar lavage cell interleukin-4, interleukin-5 and interferon-gamma cytokine gene expression. Am. Rev. Respir. Dis. 148: 401-406, 1993.
36. SCHLEIMER, R. P.: Effects of glucocorticoids on inflammatory cells relevant to their therapeutic applications in airway. Am. Rev. Respir. Dis. 141: 59-69, 1990.
37. SELIG, W. AND TOCKER, J.: Effect of interleukin-1 receptor antagonist on antigen-induced pulmonary responses in guinea pigs. Eur. J. Pharmacol. 213: 331-336, 1982.
38. SMART, S. J. AND CASALE, T. B.: TNF-alpha-induced transendothelial neutrophil migration is IL-8 dependent. Am. J. Physiol. 266: L238-L245, 1994.
39. THOMAS, P. S., YATES, D. H. AND BARNES, P. J.: Tumor necrosis factor-alpha increases airway responsiveness and sputum neutrophilia in normal human subjects. Am. J. Respir. Crit. Care Med. 152: 76-80, 1995.
40. TURNER, C. R., ANDRESEN, C. J., SMITH, W. B. AND WATSON, J. W.: Effects of rolipram on responses to acute and chronic antigen exposure in monkeys. Am. J. Respir. Crit. Care Med. 149: 1153-1159, 1994.
41. 4 and PAF receptor antagonists in decreasing antigen-induced airway microvascular leakage. Adv. Prostaglandin Thromboxane Leukotriene Res. 23: 271-273, 1995.
42. WATSON, M. L., SMITH, D., BOURNE, A. D., THOMPSON, R. C. AND WESTWICK, J.: Cytokines contribute to airway dysfunction in antigen-challenged guinea pigs: inhibition of airway hyperreactivity, pulmonary eosinophil accumulation, and tumor necrosis factor generation by pretreatment with an interleukin-1 receptor antagonist. Am. J. Respir. Cell Mol. Biol. 8: 365-369, 1993.
43. WERSHIL, B. K., FURATA, G. T., LAVIGNE, J. A., CHOUDHURY, A. R., WANG, Z-S AND GALLI, S.: J. Dexamethasone and cyclosporin A suppress mast cell-leukocyte cytokine cascades. J. Immunol. 154: 1391-1398, 1995.
44. WINDSOR, A. C., MULLEN, P. G., WALSH, C. J., FISHER, B. J., BLOCHER, C. R., JESMOK, G., FOWLER, A. A. AND SUGERMAN, H. J.: Delayed tumor necrosis factor alpha blockade attenuates pulmonary dysfunction and metabolic acidosis associated with experimental gram-negative sepsis. Arch. Surg. 129: 80-89, 1994.
45. YING. S., ROBINSON, D. S., VARNEY, V., MENG, Q., TSICOPOULOS, A., MOQBEL, R., DURHAM, S. R., KAY, A. B. AND HAMID, Q.: TNF alpha mRNA expression in allergic inflammation. Clin. Exp. Allergy 21: 745-750, 1991.
46. ZUANY-AMORIM, C., HAILE, S., LEDUC, D., DUMAREY, C., HUERRE, M., VARGAFTIG, B. B. AND PRETOLANI, M.: Interleukin-10 inhibits antigen-induced cellular recruitment into the airways of sensitized mice. J. Clin Invest. 95: 2644-2651, 1995.