The novel UGT1 gene complex links bilirubin, xenobiotics, and therapeutic drug metabolism by encoding UDP-glucuronosyltransferase isozymes with a common carboxyl terminus

Journal of Pharmacokinetics and Biopharmaceutics

Volumn 24, Issue 5, 1996, Pages 491-508

  Owens, Ida S ^a   Ritter, Joseph K ^a   Yeatman, Matthew T ^a   Chen, Fan ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

Bilirubin UDP glucuronosyltransferase; Genetic defects; Gentic locus; Therapeutic drugs; Xenobiotics

Indexed keywords

BILIRUBIN; GLUCURONOSYLTRANSFERASE; ISOENZYME; MESSENGER RNA; PARACETAMOL; PHENOBARBITAL; XENOBIOTIC AGENT;

ARTICLE; DRUG METABOLISM; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; PRIORITY JOURNAL;

ANIMALS; CLONING, MOLECULAR; CRIGLER-NAJJAR SYNDROME; DNA; FEMALE; GENOTYPE; GILBERT DISEASE; GLUCURONOSYLTRANSFERASE; HUMANS; HYPERBILIRUBINEMIA, HEREDITARY; MALE; MOLECULAR SEQUENCE DATA; PHARMACEUTICAL PREPARATIONS; PHENOTYPE; RATS; RATS, GUNN; RNA; XENOBIOTICS;

EID: 0030433005     PISSN: 0090466X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02353476     Document Type: Article

References (16)

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