Influence of the last amino acid in the nascent peptide on EF-Tu during decoding

Biochimie

Volumn 78, Issue 11-12, 1996, Pages 953-958

  Mottagui Tabar, S ^a   Isaksson, L A ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

EF Tu; Nascent peptide; Suppressor tRNA; Translation termination

Indexed keywords

ELONGATION FACTOR TU; MUTANT PROTEIN; RIBOSOME PROTEIN; TRANSFER RNA; TRANSLATION TERMINATION FACTOR;

AMINO ACID SEQUENCE; CARBOXY TERMINAL SEQUENCE; CODON; CONFERENCE PAPER; CONTROLLED STUDY; NONHUMAN; PROTEIN RNA BINDING; PROTEIN STRUCTURE; STOP CODON; TRANSLATION REGULATION;

EID: 0030432485     PISSN: 03009084     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-9084(97)86717-X     Document Type: Conference Paper

References (26)

1. 1 Tapio S, Isaksson LA (1988) Antagonistic effects of mutant elongation factor Tu and ribosomal protein S12 on control of transnational accuracy, suppression and cellular growth. Biochimie 70, 273-281
2. 2 Tapio S, Isaksson LA (1989) Antisuppression by mutations in elongation factor Tu. Eur J Bioch 188, 339-346
3. 3 Rydén SM, Isaksson LA (1984) A temperature-sensitive mutant of Escherichia coli that shows enhanced misreading of UAG/A and increase efficiency for some tRNA nonsense suppressors. Mol Gen Genet 193, 38-45
4. 4 Mikuni O, Kawakami K, Nakamura Y (1991) Sequence and functional analysis of mutations in the gene encoding peptide-chain-release factor-2 of Escherichia coli. Biochimie 73, 1509-1516
5. 5 Kirsebom LA, Isaksson LA (1986) Functional interactions in vivo between suppressor tRNA and mutationally altered ribosomal protein S4. Mol Gen Genet 205, 240-247
6. 6 Bilgin N, Cleasen F, Pahverk H, Ehrenberg M (1992) Kinetic properties of Escherichia coli ribosomes with altered forms of S12. J Mol Biol 224 1011-1027
7. 7 Fáxen M, Kirsebom L, Isaksson LA (1988) Is efficiency of suppressor tRNA controlled at the level of ribosomal proofreading in vivo? J Bacteriol 170, 3756-3760
8. 8 Brown CM, Tate WP (1994) Direct recognition of mRNA stop signals by Escherichia coli polypeptide chain release factor two. J Biol Chem 269, 33164-33170
9. 9 Yarus M, Cline SW, Wier P, Breen L, Thompson RC (1986) Actions of the anticodon arm in translation on the phenotypes of RNA mutants. J Mol Biol 192, 235-255
10. 10 Yarus M, Smith D (1993) Transfer RNA on the ribosome: a waggle theory, In: Transfer RNA (Söll D, Rajbhandary U, eds) American Society for Microbiology Washington DC, 451-454
11. 11 Buckingham RH, Sörensen P, Pagel FT, Hijazi KA, Mims BH, Brechemier-Baey D, Murgola EJ (1990) Third position base changes in codons 5′ and 3′ adjacent UGA codons affect UGA suppression in vivo. Biochim Biophys Acta 1050, 259-260
12. 12 Curran JF (1994) Decoding with the A:I wobble pair is inefficient. Nucleic Acids Res 9, 29-32
13. 13 Björnsson A, Mottagui-Tabar S, Isaksson LA (1996) Structure of the C-terminal end of the nascent peptide influences translation termination. EMBO J 15, 1696-1704
14. 14 Mottagui-Tabar S, Björnsson A, Isaksson LA (1994) The second to the last amino acid in the nascent peptide as a codon context determinant. EMBO J 13, 249-257
15. 6A37 in tRNA, mutation in rpsD (S4) or streptomycin. J Mol Biol 232, 1017-1029
16. 16 Björnsson A, Isaksson LA (1988) Test system for measurement of transiational activity in vivo. Nucleosides Nucleotides 7, 565-569
17. 17 Vijgenboom E, Vink T, Kraal B, Bosch L (1985) Mutants of elongation factor EF-Tu, a new class of nonsense suppressors. EMBO J 4, 1049-1052
18. 18 Abdulkarim F, Tuohy TMF, Buckingham RH, Hughes D (1991) Missense substitutions lethal to essential functions of EF-Tu. Biochimie 73, 1457-1464
19. 19 Vacher J, Grosjean H, Houssier C, Buckingham RH (1984) The effect of point mutations affecting Escherichia coli tryptophan tRNA on anticodoncodon interactions and on UGA suppression. J Mol Biol 177, 329-342
20. 20 Zhang SP, Rydén Aulin M, Isaksson LA (1996) Functional interaction between release factor one and P-site peptidyl-tRNA on the ribosome. J Mol Biol 261, 98-107
21. 21 Nakamura Y, Ito K, Isaksson LA (1996) Emerging understanding of translation termination. Cell 87, 147-150
22. 22 Ito K, Ebihara K, Uno M, Nakamura Y (1996) Conserved motifs in prokaryotic and eukaryotic polypeptide release factors: tRNA-protein mimicry hypothesis. Proc Natl Acad Sci USA 93, 5443-5448
23. 23 Miller JH (1972) In: Experiments in Molecular Genetics. Cold Spring Harbor Laboratory, CHSL Press, New York
24. 24 Tubulekas I, Hughes D (1993) Suppression of rpsL phenotypes by tuf mutations reveals a unique relationship between translation elongation and growth rate. Mol Microbiol 7, 275-284
25. 25 Creighton TE, (1993) In: Proteins: Structures, 2nd edn. WH Freeman and Company, NY, 4
26. 26 Hardy PM (1985) The protein amino acids. In: Chemistry and biochemistry of the amino acids. (Barrett GC, ed) Chapmann and Hall Ltd, London, 7-24