Metal lothionein Induction in Calcifying Growth Plate Cartilage Chondrocytes

Connective Tissue Research

Volumn 35, Issue 42008, 1996, Pages 189-195

  Litchfield, Theresa M ^a   Sauer, Glenn R ^a  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Cadmium; cell culture; dexamethasone; vitamin D; zinc

Indexed keywords

BUTYRIC ACID; BUTYRIC ACID DERIVATIVE; CADMIUM CHLORIDE; CHLORIDE; CYSTEINE; DEXAMETHASONE; DIHYDROXYCOLECALCIFEROL; INTERLEUKIN 1; METALLOTHIONEIN; METHIONINE; ZINC CHLORIDE; ZINC DERIVATIVE;

ANIMAL; BIOSYNTHESIS; CELL CULTURE; CHICKEN; CONFERENCE PAPER; CULTURE MEDIUM; CYTOLOGY; DRUG EFFECT; GROWTH PLATE; METABOLISM;

ANIMALS; BUTYRIC ACID; BUTYRIC ACIDS; CADMIUM CHLORIDE; CELLS, CULTURED; CHICKENS; CHLORIDES; CULTURE MEDIA; CYSTEINE; DEXAMETHASONE; DIHYDROXYCHOLECALCIFEROLS; GROWTH PLATE; INTERLEUKIN-1; METALLOTHIONEIN; METHIONINE; ZINC COMPOUNDS;

ANIMALIA; GALLUS GALLUS;

EID: 0030431195     PISSN: 03008207     EISSN: 16078438     Source Type: Journal    
DOI: 10.3109/03008209609029191     Document Type: Article

References (20)

1. Guggenheim K., Caster D. The role of manganese, copper, and zinc in the physiology of bone and teeth. Biological Mineralization, I. Zipkin. John Wiley & Sons, New York 1981; 443 – 462
2. Bird E. D., Thomas W. C. Effect of various metals on mineralization in vitro. Proc. Soc. Exp. Biol. Med. 1963; 112: 640 – 643
3. Nogawa K. ltai-itai disease and follow-up studies. Cadmium in the Environment, Part II, J. O. Nriagu. John Wiley & Sons, New York 1981; 1 – 37
4. Genge B. R., Sauer G. R., Wu L. N. Y., Mclean F. M., Keller P. J., Wuthier R. E. Correlation between loss of alkaline phosphatase activity and accumulation of calcium during matrix vesicle-mediated mineralization. J. Biol. Chem. 1988; 263: 18513 – 18519
5. Sauer G. R., Genge B. R., Wu L. N. Y., Donachy J. E. A facilitative role for carbonic anhydrase activity in matrix vesicle mineralization. Bone & Mineral 1994; 26: 69 – 79
6. Sauer G. R., Genge B. R., Adkisson H. D., Wuthier R. E. Regulatory effect of endogenous zinc, and inhibitory effect of toxic metal ions on calcium accumulation by matrix vesicles in vitro. Bone & Mineral 1989; 7: 233 – 244
7. Hamer D. H. Metallothionein. Ann. Rev. Biochem. 1986; 55: 913 – 951
8. Wu Licia N. Y., Ishikawa I., Sauer G. R., Genge B. R., Mwale F., Mishima H., Wuthier R. E. Morphological and biochemical characterization of mineralizing primary cultures of avian growth plate chondrocytes: Evidence for cellular processing of Ca2+ and Pi prior to matrix mineralization. J. Cell. Biochem. 1995; 57: 218 – 237
9. Eaton D. L., Cherian M. G. Determination of metallothionein in tissues by cadmium-hemoglobin affinity assay. Meth. Enzymol. 1991; 205: 83 – 88
10. Zafarullah M., Su S., Gedamu L. Basal and inducible expression of metallothionein and heat shock protein 70 genes in bovine articular chondrocytes. Exp. Cell. Res. 1993; 208: 371 – 377
11. Klaasen C. D., Liu J. Induction of metallothionein in primary rat hepatocyte cultures. Meth. Enzymol. 1991; 205: 567 – 574
12. Angel C. R., Thomas D. J., Swanson S. A. Toxicity of cadmium to rat osteosarcoma cells (ROS 17/2.8): Protective effect of 1α, 25-dihydroxyvitamin D3. Toxicol. Appl. Pharmacol 1990; 103: 113 – 120
13. Thomas D. J., Angel C. R., Swanson S. A., Caffrey C. A. Effect of sodium butyrate on metallothionein induction and cadmium cytotoxicity in ROS 17/2.8 cells. Toxicol 1991; 66: 35 – 46
14. Wei D., Andrews G. K. Molecular cloning of chicken metallothionein. Deduction of the complete amino acid sequence and analysis of expression using cloned cDNA. Nucl Acid. Res. 1988; 16: 537 – 553
15. Cousins R. J. Metal elements and gene expression. Annu. Rev. Nutr. 1994; 14: 449 – 469
16. Takeda A., Norris J. S., Iversen P. L., Ebadi M. Antisense oligonucleotide of c-myc discriminates between zinc- and dexamethasone-induced synthesis of metallothionein. Pharmacol 1994; 48: 119 – 126
17. Stein G. S., Lian J. B. Molecular mechanisms mediating developmental and hormone-regulated expression of genes in osteoblasts: An integrated relationship of cell growth and differentiation. Cellular and Molecular Biology of Bone, M. Noda. Academic Press, New York 1993; 48 – 95
18. Iwamoto M., Yagami K., LuValle P., Olsen B. R. Expression and role of c-myc in chondrocytes undergoing endochondral ossification. J. Biol. Chem. 1993; 268: 9645 – 9652
19. Subramaniam M., Colvard D., Keeting P. E., Rasmussen K. Glucocorticoid regulation of alkaline phosphatase, osteocalcin, and proto-oncogenes in normal human osteoblast-like cells. J. Cell. Biochem. 1992; 50: 411 – 424
20. Rhee K., Bresnahan W., Hirai A., Hirai M., Thompson E. A. c-Myc and cyclin D3 (CcnD3) genes are independent targets for glucocorticoid inhibition of lymphoid cell proliferation. Cancer Res. 1995; 55: 4188 – 4195