Alpha-1 adrenergic regulation of lactate production by white adipocytes

Journal of Pharmacology and Experimental Therapeutics

Volumn 277, Issue 1, 1996, Pages 235-238

  Faintrenie, G ^a   Geloen A ^a,b  

^a Lab Thermoregulation ME   (France)

^b UNIVERSITÉ LYON 1   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; BRIMONIDINE; CATECHOLAMINE; ISOPRENALINE; LACTIC ACID; NORADRENALIN; PHENYLEPHRINE; PRAZOSIN; RECEPTOR SUBTYPE;

ANIMAL CELL; ARTICLE; CATECHOLAMINE SYNTHESIS; CONTROLLED STUDY; GLUCONEOGENESIS; GLUCOSE METABOLISM; GLYCOGENOLYSIS; INSULIN RESISTANCE; LACTATE BLOOD LEVEL; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; WHITE ADIPOSE TISSUE;

ADIPOCYTES; ANIMALS; GLYCEROL; ISOPROTERENOL; LACTATES; LACTIC ACID; MALE; NOREPINEPHRINE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA-1;

EID: 0030430032     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. BURNS, T. W., LANGLEY, P. E., TERRY, B. E. AND BYLUND, D.: Pharmacological characterizations of adrenergic receptors in human adipocytes. J. Clin. Invest. 67: 467-475, 1981.
2. CHEN, Y. D. I., VARASTEH, B. B. AND REAVEN, G. M.: Plasma lactate concentration in obesity and type 2 diabetes. Diabete and Metabolisme 19: 348-354, 1993.
3. CONSOLI, A., NURJHAN, N. AND GERICH, J.: Rates of appearance and disappearance of plasma lactate after oral glucose: Implications for indirect-pathway hepatic glycogen repletion in man. Clin. Physiol. Biochem. 7: 70-78, 1989.
4. CRANDALL, D. L., FRIED, S. K., FRANCENDESE, A. A., NICKEL, M. AND DIGIROLAMO, M.: Lactate release from isolated rat adipocytes. Influence of cell size, glucose concentration, insulin and epinephrine. Horm. Metab. Res. 15: 326-329, 1983.
5. DIGIROLAMO, M., NEWBY, F. D. AND LOVEJOY, J.: Lactate production in adipose tissue: A regulated function with extra-adipose implications. FASEB J. 6: 2405-2412, 1992.
6. 2 effects of catecholamines. Life Sci. 26: 1183-1194, 1980.
7. FAIN, J. N. AND GARCIA-SAINZ, J. A.: Adrenergic regulation of adipocyte metabolism. J. Lip. Res. 24: 945-966, 1983.
8. GROFF, J. L., STUGARD, C. E., MAYS, C. J. AND DIGIROLAMO, M.: Glucose metabolism in isolated rat adipocytes: Estimate of total recovery by the product summation method. J. Lab. Clin. Med. 119: 216-220, 1992.
9. HONNOR, R. C., DHILLON, G. S. AND LONDOS, C.: cAMP-dependent protein kinase and lipolysis in rat adipocytes. Definition of steady-state relationship with lipolytic and antilipolytic modulators. J. Biol. Chem. 260: 15130-15138, 1985.
10. 1 adrenoceptor. J. Lip. Res. 32: 191-196, 1991.
11. LAFONTAN, M. AND BERLAN, M.: Fat cell adrenergic receptors and the control of white and brown fat cell function. J. Lip. Res. 34: 1057-1091, 1993.
12. LAWRENCE, J C. AND LARNER, J.: Evidence for alpha-adrenergic activation of phosphorylase and inactivation of glycogen synthase in rat adipocytes: Effects of alpha and beta-adrenergic agonists and antagonists on glycogen synthase and phosphorylase. Mol. Pharmacol. 13: 1060-1075, 1977.
13. LOVEJOY, J., MELLEN, B. AND DIGIROLAMO, M.: Lactate generation following glucose ingestion: Relation to obesity, carbohydrate tolerance and insulin sensitivity. Int. J. Obesity 14: 843-855, 1990.
14. NEWGARD, C. B., HIRSCH, L. J., FOSTER, D. W. AND MCGARRY, J. D.: Studies on the mechanism by which exogenous glucose is converted into liver glycogen in the rat. J. Biol. Chem. 258(13): 8046-8052, 1983.
15. PASSONEAU, V.: Metabolites: Carbohydrate metabolism, In Methods of Enzymatic Analysis, ed. by H. U. Bergmeryer, pp. 1468-1470, Verlag chemie, Weinheim and Academic Press, New-York, 1974.
16. RODBELL, M.: Metabolism of isolated fat cells. J. Biol. Chem. 239 (2): 375-380, 1964.
17. 1B-adrenoceptors. Mol. Pharmacol. 42: 403-406, 1992.
18. 2+ influx. Mol. Pharmacol. 36: 166-176, 1989.
19. WAHLEFELT, A. W.: Metabolites: Carbohydrate metabolism, In Methods of Enzymatic Analysis, ed. by H. U. Bergmeryer, pp. 1878-1880, Verlag chemie, Weinheim and Academic Press, New-York, 1974.
20. YKI-JARVINEN, H., BOGARDUS, C. AND FOLEY, J. E.: Regulation of plasma lactate concentration in resting human subjects. Metabolism 39(8): 859-864, 1990.