Purinergic mechanisms in inflammation

Drug Development Research

Volumn 39, Issue 3-4, 1996, Pages 426-435

  Cronstein, Bruce N ^a,d   Bouma, Maarten G ^b   Becker, Bernhard F ^c  

^a NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c UNIVERSITY OF MUNICH   (Germany)

^d Division of Rheumatology   (United States)

Author keywords

Adenosine; Cytokines; Reactive oxygen

Indexed keywords

ADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE RECEPTOR; ANTIINFLAMMATORY AGENT; METHOTREXATE; SALAZOSULFAPYRIDINE;

CELL ADHESION; CONFERENCE PAPER; HUMAN; INFLAMMATION; NONHUMAN; VASCULAR ENDOTHELIUM;

EID: 0030428260     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2299(199611/12)39:3/4<426::AID-DDR24>3.0.CO;2-Y     Document Type: Conference Paper

References (75)

1. Agarwal KG (1993): Modulation of vasopressin actions on human platelets by plasma adenosine and theophylline: Gender differences. J Cardiovasc Pharmacol 21:1012-1018.
2. Baggott JE, Morgan SL, Ha T, Vaughn WH, Hine RJ (1992): Inhibition of folate-dependent enzymes by non-steroidal anti-inflammatory drugs. Biochem J 282:197-202.
3. Barankiewicz J, Ronlov G, Jimenez R, Gruber HE (1990a): Selective adenosine release from human B but not T lymphoid cell line. J Biol Chem 265:15738-15743.
4. Barankiewicz J, Jimenez R, Ronlov G, Magill M, Gruber HE (1990b): Alteration of purine metabolism by AICA-riboside in human B lymphoblasts. Arch Biochom Biophys 282:377-385.
5. Bardenbeuer HJ, Fabry A, Höfling B, Peter K (1994): Adenosine: A sensitive marker of myocardial ischemia in man. Cardiovasc Res 28:656-662.
6. Becker BF, Zahler S, Raschke P, Schwartz LM, Beblo S (1992): Adenosine enhances neutrophil sticking in the coronary system: A novel mechanism contributing to cardiac reperfusion damage. Pharm Pharmacol Lett 2:8-11.
7. Becker BF, Raschke P, Bardenheuer H, Gerlach E (1993): Gramilocytes, reactive oxygen species and uric acid: Their role in postischemic reperfusion damage of the heart. Pharm Pharmacol Lett 3:139-142.
8. Becker BE Seligmann C, Beblo S, Zahler S (1995): Physiologie und Pathophysiologie der Hämostase. In Baumann G (ed): Antikoagulantien und Thrombozytenaggregationshemmer bei kardialen Erkrankungen: Nutzen und Risiko. Nürnberg, Klaus Pia Verlag-sgesellsebaft, pp H-17.
9. Becker BF, Kupatt G, Raschke P, Zahler S (1996a): Microcirculatory disturbances due to activated leukocytes in ischemic and reperfusion injury. In Kamada T, Shiga T, McGuskey RS (eds): Tissue perfusion and organ function: Ischemia/reperfusion injury. Amsterdam: Elsevier Science Publishers, pp 97-107.
10. Becker BF, Zahler S, Seligmann C, Kupatt C, Habazettl H (1996b): Interaction of adenosine with leukocytes and blood platelets. Z Kardiol (in press).
11. Becker BE Zahler S, Kupatt G, Münch G, Richardt G (1996c): Importance of intracoronary adenosine concentration for modulation of leukocyte-endothelial interaction. Pflügers Arch 431 (Suppl 6):R128.
12. Boni GVR (1962): Aggregation of blood platelets by adenosine diphosphate and its reversal. Nature 194:927-929.
13. Bouma MG, Stad RK, van den Wildenberg FAJM, Buurman WA (1994): Differential regulatory effects of adenosine on cytokine release by activated human monocytes. J Immunol 153:4159-4168.
14. Brady AJB, Williams FM, Williams TJ (1992): Inflammatory injury in myocardial ischemia. Clin Sci 83:511-518.
15. Gronstein BN, Kramer SB, Weissmann G, Hirschhorn R (1983): Adenosine: A physiological modulator of superoxide anion generation by human neutrophils. J Exp Med 158:1160-1177.
16. Gronstein BN, Rosenstein ED, Kramer SB, Weissmann G, Hirschhorn R (1985): Adenosine: a physiologic modulator of superoxide anion generation by human neutrophils. Adenosine acts via an A2 receptor on human neutrophils. J Immunol 135:1366-1371.
17. Gronstein BN, Levin RI, Belanoff J, Weissmann G, Hirschhorn R (1986): Adenosine: An endogenous inhibitor of ncutrophil-mediated injury to eudothelial cells. J Glin Invest 78:760-770.
18. 2 receptors which promote chemotaxis and inhibit O2-generation, respectively. J Clin Invest 85:1150-1157.
19. Cronstein BN, Eberle MA, Gruber HE, Levin RI (1991): Methotrexale inhibits neutrophil function by stimulating adenosine release from connective tissue cells. Proc Natl Acad Sci USA 88:2441-2445.
20. 2 receptors. J Immunol 148:2201.
21. Cronstein BN, Naime D, Ostad E (1993): The antiinflammatory mechanism of methotrexate: Increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vivo model of inflammation. J Clin Invest 92:2675-2682.
22. Cronstein BN, Naime D, Firestein GS (1995): The antiinflammatory effects of an adenosine kinase inhibitor are mediated by adenosine. Arth Rheum 38:1040-1045.
23. Chabner BA, Allegra CJ, Curt GA, Clendeninn NJ, Baram J, Koizumi S, Drake JC, Jolivet J (1985): Polyglutamation of methotrexate: Is methotrexate a prodrug? J Clin Invest 76:907-912.
24. De Servi S, Mazzone A, Ricevuti G, Fioravanti A, Bramucci E, Angoli L, Stefano G, Sepecchia G (1990): Granulocyte activation after coronary angioplasty in humans. Circulation 82:140-146.
25. Engler R (1987): Consequences of activation and adenosine-mediated inhibition of granulocytes during myocardial ischemia. Fed Proc 46:2407.
26. Entman ML, Smith CW (1994): Postreperfusion inflammation: A model for reaction to injury in cardiovascular disease. Cardiovasc Res 28:1301-1311.
27. Firestein GS, Boyle D, Bullough DA, Gruber HE, Sajjadi EG, Montag A, Sambol B, Mullane K (1994): Protective effect of an adenosine kinase inhibitor in septic shock. J Immunol 152:5853-5859.
28. Firestein GS, Bullough DA, Erion MD, Jimenez R, RamirezWeinhouse M, Barankiewicz J, Smith CW, Gruber HE, Mullane KM (1995): Inhibition of neutrophil adhesion by adenosine and an adenosine kinase inhibitor: the role of selectins. J Immunol 154:326-334.
29. Fong Y, Lowry SF (1990): Tumor necrosis factor in the pathophysiology of infection and sepsis, Clin Immunol Immunopathol 55:157.
30. Furst DE (1995): Practical clinical pharmacology and drug interactions of low-dose methotrexate therapy in rheumatoid arthritis. Br J Rheum 34(Suppl 2):20-25.
31. Gadangi P, Longaker M, Naime D, Levin RI, Recht PA, Montesinos MC, Buckley MT, Carlin G, Cronstein BN (1996): The autiinflammatory mechanism of sulfasalazine is related to adenosine release at inflamed sites. J Immunol 156:1937-1941.
32. Gawaz M, Neumann F-J, Ott I, Schiessler A, Schömig A (1996): Platelet function in acute myocardial infarction treated with direct angioplasty. Circulation 93:229-237.
33. Gerlach E, Becker BF (1993): Interaktion von Blut und Gefäßwand: Hämostascologische Aspekte. Z Kardiol 82(Suppl 5):13-21.
34. Gerlach E, Deuticke B, Dreisbach RH (1963): Der Nukleotid-Abbau im Herzmuskel bei Sauerstoffmangel und seine mögliche Bedeutung für die Coronardurchblutung. Naturwissenschaften 50:228-229.
35. Gruber HE, Hoffer ME, McAllister DR, Laikind PK, Lane TA, Schmid-Schoenbein GW, Engler RL (1989): Increased adenosine concentration in blood from ischemic myocardium by AICA riboside: effects on flow, granulocytes and injury. Circulation 80:1400-1411.
36. Habazettl H, Kupatt C, Zahler S, Becker BF, Gerlach E, Messmer K (1996): Nitric oxide modulates post-ischemic venular leukocyte adhesion in isolated guinea pig hearts. In Messmer K, Kübler WM (eds): Proceedings 6th World Congress for Microcirculation. Bologna: Monduzzi Editore, pp 729-733.
37. Hansen PR (1995): Role of nentrophils in myocardial ischemia and reperfusion. Circulation 91:1872-1885.
38. Kupatt C, Zahler S, Seligmann C, Massoudy P, Becker BE Gerlach E (1996): Nitric oxide mitigates leukocyte adhesion and vascular permeability changes after myocardial ischemia. J Mol Cell Cardiol 28:643-654.
39. Le Moine O, Stordeur P, Schandené L, Marchant A, De Groote D, Goldman M, Devière J (1996): Adenosine enhances IL-10 secretion by human monocytes. J Immunol 156:4408.
40. 1-selective adenosine agonist on rat acute models of inflammation and neiitrophil function. Agents Actions 34:25-27.
41. Lorant DE, Patel KD, McIntyre TM, McEver RP, Prescott SM, Zimmerman GA (1991): Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of nentrophils. J Cell Biol 115:223-234.
42. Lucchesi BR (1994): Complement, nentrophils and free radicals: Mediators of reperfusion injury. Arzneim-Forsch/Drug Res 44:420-432.
43. Mantovani A, Dejana E (1989): Cytokines as communication signals between leukocytes and endothelial cells. Immunol Today 10:370.
44. Marts BC, Baudendistel LJ, Naunheim KS, Dahms TE (1993): Protective effect of 2-chloroadenosine on lung ischemia reperfusion injury. J Surg Res 54:523.
45. Morgan SL, Baggott JE, Vaughn WH, Young PK, Austin JV, Krumdieek CL, Alarcon GS (1990): The effect of folic acid supplementation on the toxicity of low-dose methotrexate in patients with Rheumatoid Arthritis. Arth Rheum 33:9-18.
46. Morgan SL, Baggott JE, Vaughn WH, Austin JS, Veitch TA, Lee JY, Koopman WJ, Krumdieck CL, Alarcon CS (1994): Supplementation with folic acid during methotrexate therapy for rheumatoid arthritis. A double-blind, placebo-controlled trial. Ann Int Med 121:833-841.
47. Nolte D, Lehr H-A, Messmer K (1991): Adenosine inhibits postischemic leukocyte-endothelium interaction in postcapillary venules of the hamster. Am J Physiol 261:11651-11655.
48. 2 receptor. Naunyn-Schmiedeberg's Arch Pharmacol 346:234-237.
49. Palabrica T, Lobb R, Furie BC, Aronovitz M, Benjamin C, Hsu Y-M, Sajer SA, Furie B (1992): Leukocyte accumulation promoting fibrin deposition is mediated in vivo by P-selectin on adherent platelets. Nature 359:848-851.
50. Parkinson FE, Clanachan AS (1991): Adenosine receptors and nucleoside transport sites in cardiac cells. Br J Pharmacol 104:399-405.
51. Parmely MJ, Zhou W-W, Edwards CK III, Borcherding DR, Silverstein R, Morrison DC (1993): Adenosine and a related carbocyclic nucleoside analogue selectively inhibit tumor necrosis factor-alpha production and protect mice against endotoxin challenge. J Immunol 151:389-396.
52. 2) receptor selective agonists. Int J Immunopharmacol 17:221-224.
53. Raschke P, Becker BF (1995): Adenosine and PAF-dependent mechanisms lead to myocardial reperfusion injury by polymorphonuclear neutrophils after brief ischaemia. Cardiovasc Res 29:569-576.
54. Raschke P, Becker BF, Leipert B, Schwartz LM, Zahler S, Gerlach E (1993): Postischemic dysfunction of the heart induced by small numbers of neutrophils via formation of hypochlorous acid. Basic Res Cardiol 88:321-339.
55. Roberts PA, Newby AC, Hallett MB, Campbell AK (1985): Inhibition by adenosine of reactive oxygen metabolite production by human polymorphonuclear leucocytes. Biochem J 227:669-674.
56. Rosengren S, Bong GW, Firestein CS (1995): Anti-inflammatory effects of an adenosine kinase inhibitor: decreased neutrophil accumulation and vascular leakage. J Immunol 154:5444-5451.
57. Ruggeri ZM (1994): Glycoprotein Ib and von Willebrand factor in the process of thrombus formation. Ann NY Acud Sci 714:200-210.
58. 3 adenosine receptors. J Immunol 156:3435-3442.
59. 2 receptors are inhibitory. J Immunol 145:2235-2240.
60. 1 receptors. J Immunol 151:2775.
61. Schrier DJ, Lesch ME, Wright CD, Gilbertsen RB (1990): The antiinflammatory effects of adenosine receptor agonists on the carrageenan-induced pleural inflammatory response in rats. J Immunol 145:1874-1879.
62. Schwartz LM, Raschke P, Becker BF, Gerlach E (1993): Adenosine contributes to neutrophil-mediated loss of myocardial function in postischemie guinea pig hearts. J Mol Cell Cardiol 25:927-938.
63. Seekamp A, Warren JS, Remick DG, Till GO, Ward PA (1993): Requirements for tumor necrosis factor-a and interleukin-1 in limb ischemia/reperfusion injury and associated lung injury. Am J Pathol 143:453.
64. Seligmann C, Becker BF Knpatt C, Beblo S, Gerlach K (1995a): Endogenons adenosine prevents platelet adhesion in the coronary system during early reperfusion, but not during low-flow ischemia. Pflügers Arch 429(Suppl 6):R109.
65. 2-receptor mediated mechanism. Eur Heart J 16(Abstr Suppl):361.
66. Shalaby MR, Waage A, Aarden L, Espevik T (1989): Endotoxin, tumor necrosis factor-α and interleukin-1 induce interleukin-6 production in vivo. Clin Immunol Immunopathol 53:488.
67. Sixma JJ, de Groot PG (1994): Regulation of platelet adhesion to the vessel wall. Ann NY Acad Sci 714:190-199.
68. Smolenski RT, Kochan Z, McDouall R, Page C, Seymour A-ML, Yacoub MH (1994): Endothelial nucleotide metabolism and adenosine production. Cardiovasc Res 28:100.
69. Stad RK, Buurman WA (1994): Current views on structure and function of endothelial adhesion molecules. Cell Adhes Commun 2:261.
70. Strieter RM, Coletti LM, Metinko AP, Rolfe MW, DeMeester SR, Standiford TJ, Kunkel SL (1993): The role of cytokine networks mediating inflammation and ischemia-reperfusion injury. In Sehlag G, Redl H, Traber D (eds): Shock, Sepsis and Organ Failure. Berlin: Springer Verlag, pp. 205-230.
71. 2 receptors, adenosine inhibits production of tumor necrosis factor-α of endotoxin-stimulated polymorphonuclear leukocytes. J Lab Clin Med 126:275-282.
72. Venturini CM, Kaplan JE (1992): Thrombin induces platelet adhesion to endothelial cells. Semin Thromb Hemostasis 18:275-283.
73. Weinblatt ME, Coblyn JS, Fox DA, Fraser PA, Holdsworth DE, Glass DN, Trentham DE (1985): Efficacy of low-dose methotrexate in rhenmatoid arthritis. N Engl J Med 312:818-822.
74. 1-receptors enhances adhesion of neutrophils in the intact guinea pig coronary system. Cardiovasc Res 28:1366-1372.
75. Zahler S, Kupatt C, Becker BF, Gerlach E (1996): Granuloeyte activation by passage through a reperfused coronary bed: functional consequences of ACE-inhibition. In Messmer K, Kübler WM (eds): Proceedings 6th World Congress for Microcirculation. Bologna: Monduzzi Editore, pp 461-465.