The effects of opioid receptor antagonism on the discriminative stimulus effects of cocaine and d-amphetamine in the rat

Behavioural Pharmacology

Volumn 7, Issue 8, 1996, Pages 779-787

  Woolfolk, D R ^a   Holtzman, S G ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

funaltrexamine; cocaine; d amphetamine; drug discrimination; naloxone; naltrindole; nor binaltorphim ine; rat

Indexed keywords

BETA FUNALTREXAMINE; COCAINE; DELTA OPIATE RECEPTOR ANTAGONIST; DEXAMPHETAMINE; KAPPA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR ANTAGONIST; MU OPIATE RECEPTOR ANTAGONIST; NALOXONE; NALTRINDOLE; NORBINALTORPHIMINE; OPIATE ANTAGONIST;

ANIMAL EXPERIMENT; ARTICLE; AVOIDANCE BEHAVIOR; CONTROLLED STUDY; DISCRIMINATIVE STIMULUS; DOPAMINERGIC SYSTEM; DOSE RESPONSE; DRUG DISCRIMINATION; DRUG MECHANISM; DRUG POTENTIATION; ESCAPE BEHAVIOR; INTRACISTERNAL DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0030427833     PISSN: 09558810     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Arnold EB, Molinoff PD and Rutledge CO (1977) The relase of endogenous norepinephrine and dopamine from cerebral cortex by amphetamines. Journal of Pharmacology and Experimental Therapeutics, 202, 544-547.
2. Broadbent J, Gaspard TM and Dworkin SI (1994) Assessment of the discriminative stimulus effects of cocaine in the rat: lack of interaction with opioids. Pharmacology, Biochemistry and Behavior, 51, 379-385.
3. Callahan PM, Appel J and Cunningham KA (1991) Dopamine D1 and D2 mediation of the discriminative stimulus properties of d-amphetamine and cocaine. Psycho-pharmacology, 103, 50-55.
4. DiChiara G and Imperato A (1988) Opposite effects of mu and kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats. Journal of Pharmacology and Experimental Therapeutics, 244, 1067-1080.
5. Heidbreder C, Goldberg SR and Shippenberg TS (1993a) Inhibition of cocaine-induced sensitization by the δ-opioid receptor antagonist naltrindole. European Journal of Pharmacology, 243, 123-127.
6. Heidbreder C, Goldberg SR and Shippenberg TS (1993b) The kappa-opioid receptor agonist U-69593 attenuates cocaine-induced behavioural sensitization in the rat. Brain Research, 616, 335-338.
7. 3H]dopamine in rat brain tissue slices. Biochemical Pharmacology, 24, 847-852.
8. Holtzman SG (1974) Behavioral effects of separate and combined administration of naloxone and d-amphetamine. Journal of Pharmacology and Experimental Therapeutics, 189, 51-59.
9. Hooks SM, Jones DNC, Justice JB and Holtzman SG (1992) Naloxone reduces amphetamine-induced stimulation of locomotor activity and in vivo dopamine release in the striatum and nucleus accumbens. Pharmacology, Biochemisty and Behavior, 42, 765-770.
10. Houdi AA, Bardo MT and Van Loon GR (1989) Opioid mediation of cocaine-induced hyperactivity and reinforcement. Brain Research, 497, 195-198.
11. Jones DNC and Holtzman SG (1992) Interaction between opioid antagonists and amphetamine: evidence for mediation by central delta opioid receptors. Journal of Pharmacology and Experimental Therapeutics, 262, 638-645.
12. Jones DNC and Holtzman SG (1993) Influence of naloxone upon motor activity induced by psychomotor stimulant drugs. Psychopharmacology, 114, 215-224.
13. Jones DNC, Bowen WD, Portoghese PS and Holtzman SG (1993) δ-Opioid receptor antagonists attenuate motor activity induced by amphetamine but not cocaine. European Journal of Pharmacology, 249, 167-177.
14. Kleven MS and Woolverton WL (1990) Pharmacological characterization of the discriminative stimulus effects of cocaine in rhesus monkeys. Journal of Pharmacology and Experimental Therapeutics, 254, 312-317.
15. Koob GF, Vaccarino FJ, Amalric M and Bloom FE (1987) Positive reinforcement properties of drugs: search for neural substrate. In: Brain Reward Systems and Abuse (Eds J Engel and L Oreland), pp. 35-50. Raven Press, New York.
16. Kuczenski R and Segal DS (1994) Neurochemistry of amphetamine. In: Amphetamine and its Analogs - Psychopharmacology, Toxicology, and Abuse (Eds AK Cho and DS Segal), pp. 80-108. Academic Press Inc., San Diego.
17. Menkens K, Bilsky EJ, Wild KD, Portoghese PS, Reid LD, and Porreca F (1992) Cocaine place preference is blocked by the δ-opioid receptor antagonist, naltrindole. European Journal of Pharmacology, 219, 345-346.
18. Moore KE (1977) The action of amphetamine on neurotransmitters: a brief review. Biological Psychiatry, 12, 451-462.
19. Nielsen EB and Jepsen SA (1985) Antagonism of the amphetamine cue by both classical and atypical antipsychotic drugs. European Journal of Pharmacology, 111, 167-178.
20. Nielsen EB and Scheel-Kruger J (1986) Cueing effects of amphetamine and LSD: elicitation by direct microinjection of the drugs into the nucleus accumbens. European Journal of Pharmacology, 125, 85-92.
21. Portoghese PS, Lipkowski AW and Takemori AE (1987) Binaltorphimine and nor-binaltorphimine, potent and selective kappa-opioid receptor antagonists. Life Science, 40, 1287-1292.
22. Portoghese PS, Sultana M and Takemori AE (1988) Naltrindole, a highly selective and potent non-peptide delta opioid receptor antagonist. European Journal of Pharmacology, 146, 185-186.
23. Reid LD, Hubbell CL, Glaccum MB, Bilsky EJ, Portoghese PS and Porreca F (1993) Naltrindole, an opioid delta receptor antagonist, blocks cocaine-induced facilitation of responding for rewarding brain stimulation. Life Science, 52, 67-71.
24. Roberts DCS and Koob GF (1982) Disruption of cocaine self-administration following 6-hydroxydopamine lesions of the ventral tegmental area in rats. Pharmacology, Biochemistry and Behavior, 17, 901-904.
25. Schad CA, Justice JB and Holtzman SG (1995) Naloxone reduces the neurochemical and behavioral effects of amphetamine but not those of cocaine. European Journal of Pharmacology, 275, 9-16.
26. Scheel-Kruger J, Braestrup C, Nielson M, Golembiowska K and Mogilnicka E (1977) Cocaine: discussion on the role of dopamine in the biochemical mechanism of action. In: Cocaine and Other Stimulants (Eds EH Ellinwood and MM Kilbey), pp. 273-407, Plenum Press, New York.
27. Shippenberg TA, LeFevour A and Heidbreder C (1996) κ-opioid receptor agonists prevent sensitization to the conditioned rewarding effects of cocaine. Journal of Pharmacology and Experimental Therapeutics, 276, 545-554.
28. Smith FL, St. John C, Yang TF and Lyness WH (1989) Role of specific dopamine receptor subtypes in amphetamine discrimination. Psychopharmacology, 97, 501-506.
29. Spanagel R, Herz A and Shippenberg TS (1990) The effects of opioid peptides on dopamine release in the nucleus accumbens: an in vivo microdialysis study. Journal of Neurochemistry, 55, 1734-1740.
30. Spanagel R, Herz A and Shippenberg TS (1992) Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway. Proceedings of the National Academy of Science USA, 89, 2046-2050.
31. Spanagel R, Almeida OF and Shippenberg TS (1994) Evidence that nor-binaltorphimine can function as an antagonist at multiple opioid receptor subtypes. European Journal of Pharmacology, 264, 157-162.
32. Spealman RD and Bergman J (1992) Modulation of the discriminative stimulus effects of cocaine by mu and kappa opioids. Journal of Pharmacology and Experimental Therapeutics, 161, 607-615.
33. Spealman RD and Bergman J (1994) Opioid modulation of the discriminative stimulus effects of cocaine: comparison of μ, κ and δ agonists in squirrel monkeys discriminating low doses of cocaine. Behavioural Pharmacology, 5, 21-31.
34. Suzuki T, Mon T, Funada M, Misawa M and Nagase H (1994) Attenuation of the discriminative stimulus properties of cocaine by δ-opioid receptor antagonists. European Journal of Pharmacology, 263, 207-211.
35. Swerdlow NR, Amalric M and Koob GM (1986) Nucleus accumbens opiate-dopamine interactions and locomotor activation in the rat: evidence for a pre-synaptic locus. Pharmacology Biochemistry and Behavior, 26, 765-769.
36. Trujillo KA, Belluzzi JD and Stein L (1991) Naloxone blockade of amphetamine place preference conditioning. Psychopharmacology, 104, 265-274.
37. Walker JM, Thompson LA, Frascella J and Friederich MW (1987) Opposite effects of mu and kappa opiates on the firing-rate of dopamine cells in the substantia nigra of the rat. European Journal of Pharmacology, 134, 53-59.
38. Ward SJ, Portoghese PS and Takemori AE (1982) Pharmacological characterization in vivo of the novel opiate, beta-funaltrexamine. Journal of Pharmacology and Experimental Therapeutics, 220, 494-498.
39. Wise RA and Bozarth MA (1985) Brain mechanisms of drug reward and euphoria. Psychiatric Medicine, 3, 445-460.