Characterization of endothelin-induced nociception in mice: Evidence for a mechanistically distinct analgesic model

Journal of Pharmacology and Experimental Therapeutics

Volumn 278, Issue 1, 1996, Pages 1-7

  Raffa, Robert B ^a   Schupsky, James J ^a,b   Lee, David K H ^a,c   Jacoby, Henry I ^a,d  

^a R W JOHNSON PHARMACEUTICAL RES I   (United States)

^b Liposome Company Incorporated   (United States)

^c Allelix Biopharmaceutical Inc   (Canada)

^d Discovery Research Consultants   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ACETYLSALICYLIC ACID; ANALGESIC AGENT; BENZODIAZEPINE DERIVATIVE; CODEINE; ENDOTHELIN 1; ENDOTHELIN RECEPTOR; IBUPROFEN; INDOMETACIN; MORPHINE; NAPROXEN; PARACETAMOL; PENTAZOCINE; PHENYLQUINONE; TOLMETIN; TRAMADOL;

ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG MECHANISM; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MOUSE; NOCICEPTION; NONHUMAN; PAIN; PRIORITY JOURNAL; SMOOTH MUSCLE CONTRACTION;

ACETYLCHOLINE; ANALGESIA; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELINS; INDOMETHACIN; MALE; MICE; MICE, INBRED ICR; MODELS, NEUROLOGICAL; MORPHINE; PAIN MEASUREMENT;

EID: 0030427035     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. AHAI, H., HORI, S., ARAMORI, I., OHKUBO, H. AND NAKANISHI, S.: Cloning and expression of a cDNA encoding an endothelin receptor. Nature (Lond.) 348: 730-732, 1990.
2. BELL, R. L., YOUNG, P. R., ALBERT, D., LANNI, C., SUMMERS, J. B., BROOKS, D. W., RUBIN, P. AND CARTER, G. W.: The discovery and development of zileuton: An orally active 5-lipoxygenase inhibitor. Int. J. Immunopharmacol. 14: 505-510, 1992.
3. BRADLEY, L. M., CZAJA, J. F. AND GOLDSTEIN, R. E.: Circulatory effects of endothelin in newborn piglets. Am. J. Physiol. 259: H1613-H1617, 1990.
4. CARTER, G. W., YOUNG, P. R., ALBERT, D. H., BOUSKA, J., DYER, R., BELL, R., SUMMERS, J. B. AND BROOKS, D. W.: 5-Lipoxygenase inhibitory activity of zileuton. J. Pharmacol. Exp. Ther. 256: 929-937, 1991.
5. CHAKRABARTI, S. AND PODDAR, M. K.: Effect of diazepam on electroacupuncture induced changes in regional γ-aminobutyric acid of the rat central nervous system. Neurosci. Res. 7: 24-32, 1989.
6. COLLIER, H. O. J., DINNEEN, L. C., JOHNSON, C. A. AND SCHNEIDER, C.: The abdominal constriction response and its suppression by analgesic drugs in the mouse. Br. J. Pharmacol. 32: 295-310, 1968.
7. DAHLOF, B., GUSTAFSSON, D., HEDNER, T., JERN, S. AND HANNSSON, L.: Regional hemodynamic effects of endothelin-1 in rat and man. Unexpected adverse effects. J. Hypertension 8: 811-818, 1990.
8. DOHERTY, A. M.: Endothelins: A new challenge. J. Med. Chem. 35: 1493-1508, 1992.
9. DUBINSKY, B., GEBRE-MAHIAM, S., CAPETOLA, R. J. AND ROSENTHALE, M. E.: The antialgesic drugs: Human therapeutic correlates of their potency in laboratory animal models of hyperalgesia. Agents Actions 20: 50-60, 1987.
10. EGASHIRA, K., PIPERS, F. S., RUSH, J. E. AND MORGAN, J. P.: Effects of calcium channel blockers on coronary vasoconstriction induced by endothelin-1 in closed chest pigs. J. Am. Coll. Cardiol. 16: 1296-1303, 1990.
11. FERREIRA, S. H., ROMITELLI, M. AND DE NUCCI, G.: Endothelin-1 participation in overt and inflammatory pain. J. Cardiovasc. Pharmacol. 13: suppl. 5, S220-S222, 1989.
12. FOLTA, A., JOSHUA, I. G. AND WEBB, R. C.: Dilator actions of endothelin in coronary resistance vessels and the abdominal aorta of the guinea pig. Life Sci. 45: 2627-2635, 1989.
13. HAEFELY, W., PIERI, L., POLC, P. AND SCHAFFNER, R.: General pharmacology and neuropharmacology of benzodiazepine derivatives. In Handbook of Experimental Pharmacology, ed. by F. Hoffmeister and G. Stille, vol. 55/II, pp. 12-262, Springer-Verlag, Berlin, 1981.
14. HILLIS, L. D. AND BRAUNWALD, E.: Coronary-artery spasm. N. Engl. J. Med. 299: 695-702, 1978.
15. IKEGAWA, R., MATSUMURA, Y., TSUKAHARA, Y., TAKAOKA, M. AND MORIMOTO, S.: Phosphoramidon, a metalloproteinase inhibitor, suppresses the secretion of endothelin-1 from cultured endothelial cells by inhibiting a big endothelin-1 converting enzyme. Biochem. Biophys. Res. Commun. 171: 669-675, 1990.
16. INOUE, A., YANAGISAWA, M., KIMURA, S., KASUYA, Y., MIYAUCHI, T., GOTO, K. AND MASAKI, T.: The human endothelin family: Three structurally and pharmacologically distinct isopeptides predicted by three different genes. Proc. Natl. Acad. Sci. U.S.A. 86: 2863-2867, 1988.
17. ISHIDA, N., TSUJIOKA, K., TOMOI, M., SAIDA, K. AND MITSUI, Y.: Differential activities of two distinct endothelin family peptides on ileum and coronary artery. FEBS Lett. 247: 337-340, 1989.
18. KAMATA, K., MIYATA, N. AND KASUYA, Y.: Effects of endothelin on the portal vein from spontaneously hypertensive and Wistar-Kyoto rats. Gen. Pharmacol. 21: 127-129, 1990.
19. KANNO, K., HIRATA, Y., NUMANO, F., EMORI, T., OHTA, K., SHICHIRI, M. AND MARUMO, F.: Endothelin-1 and vasculitis. J. Am. Med. Assoc. 264: 2868, 1990.
20. KUBOTA, K., SUN, F. Y., SUGAYA, K. AND SUNAGANE, N.: Reversal of antinociceptive effect of caerulin by benzodiazepine. J. Pharmacobiodyn. 9: 428-431, 1986.
21. KURIHARA, H., YOSHIZUMI, M., SUGIYAMA, T., YAMAOKI, K., NAGAI, R., TAKAKU, F., SATOH, H., INUI, J., YANAGISAWA, M., MASAKI, T. AND YAZAKI, Y.: The possible role of endothelin-1 in the pathogenesis of coronary vasospasm. J. Cardiovasc. Pharmacol. 13: suppl. 5, S132-S137, 1989.
22. MASERI, A., L'ABBATE, A., CHIERCHIA, S., PARODI, O., SEVERI, S., BIAGINI, A., DISTANTE, A., MARZILLI, M. AND BALLESTRA, A. M.: Significance of spasm in the pathogenesis of ischemic heart disease. Am. J. Cardiol. 44: 788-792, 1979.
23. MCMAHON, E. G., PALOMO, M. A., MOORE, W. M., MCDONALD, J. F. AND STERN, M. K.: Phoshoramidon blocks the pressor activity of porcine big endothelin-1-(1-39) in vivo and conversion of big endothelin-1-(1-39) to endothelin-1-(1-21) in vitro. Proc. Natl. Acad. Sci. U.S.A. 88: 703-707, 1991.
24. MIURA, K., YUKIMURA, T., YAMASHITA, Y., SHIMMEN, T., OKAMURA, M., YAMANAKA, S., IMANISHI, M. AND YAMAMOTO, K.: Renal and femoral vascular responses to endothelin-1 in dogs: Role of prostaglandins. J. Pharmacol. Exp. Ther. 256: 11-17, 1991.
25. MORGAN, M. M., DEPAULIS, A. AND LIEBESKIND, J. C.: Diazepam dissociates the analgesic and aversive effects of periaqueductal gray stimulation in the rat. Brain Res. 423: 395-398, 1987.
26. NIV, D., DAVIDIVICH, S., GELLER, E. AND URCA, G.: Analgesic and hyperalgesic effects in midazolam: Dependence on route of administration. Anesth. Analg. 67: 1169-1173, 1988.
27. OKADA, K., MIYAZAKI, Y., TAKADA, J., MATSUYAMA, K., YAMAKI, T. AND YAND, M.: Conversion of big endothelin-1 by membrane-bound metalloendopeptidase in cultured bovine endothelial cells. Biochem. Biophys. Res. Commun. 171: 1192-1198, 1990.
28. PIZZIKETTI, R. J., PRESSMAN, N. S., GELLER, E. B., COWAN, A. AND ADLER, M. W.: Rat cold water tail-flick: A novel analgesic test that distinguishes opioid agonists from mixed agonists-antagonists. Eur. J. Pharmacol. 119: 23-29, 1985.
29. RAFFA, R. B. AND JACOBY, H. I.: Endothelin-1, -2 and -3 directly and big-endothelin-1 indirectly elicit an abdominal constriction response in mice. Life Sci. 48: PL85-PL90, 1991.
30. RAFFA, R. B., SCHUPSKY, J. J., MAHTINEZ, R. P. AND JACOBY, H. I.: Endothelin-1-induced nociception. Life Sci. 49: PL61-PL65, 1991.
31. RODGERS, R. J. AND RANDALL, J. I.: Benzodiazepine ligands, nociception and defeat analgesia. Psychopharmacology 91: 301-315, 1987.
32. RODGERS, R. J. AND RANDALL, J. I.: Blockade of non-opioid analgesia in intruder mice by selective neuronal and non-neuronal benzodiazepine recognition site ligands. Psychopharmacology 96: 45-54, 1988,
33. SAKURAI, T., YANAGISAWA, M., TAKUWA, Y., MIYAZAKI, H., KIMURA, S., GOTO, K. AND MASAKI, T.: Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor. Nature (Lond.) 348: 732-735, 1990.
34. YANAGISAWA, M. AND MASAKI, T.: Molecular biology and biochemistry of the endothelins. Trends Pharmacol. Sci. 10: 374-378, 1989.
35. ZAMBOTTI, F., ZONTA, N., TAMMISO, R., CONCI, F., HAFNER, B., ZECCA, L., FERRARIO, P. AND MANTEGAZZA, P.: Effects of diazepam on nociception in rats. Naunyn-Schmiedeberg's Arch. Pharmacol. 344: 84-89, 1991.