Effects of the new class I antiarrhythmic agent Ro 22-9194, (2R)-2-amino-N-(2,6-dimethylphenyl)-N-[3-(3-pyridyl)propyl]propionamide D-tartrate, on ischemia- and reperfusion-induced arrhythmias in dogs: Involvement of thromboxane A2 synthase inhibitory activity

Journal of Pharmacology and Experimental Therapeutics

Volumn 279, Issue 2, 1996, Pages 877-883

  Murakami, Makoto ^a   Kinukawa, Mayumi ^a   Kanazawa, Toru ^a   Maruyama, Kazuyasu ^a   Miyagi, Masaharu ^a   Miyata, Hiroshi ^a   Ujiie, Arao ^a  

^a KISSEI PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO N (2,6 DIMETHYLPHENYL) N [3 (3 PYRIDYL)PROPYL]PROPIONAMIDE DEXTRO TARTRATE; 6 OXOPROSTAGLANDIN F1 ALPHA; ANTIARRHYTHMIC AGENT; DISOPYRAMIDE; MEXILETINE; OZAGREL; RO 22 9194; THROMBOXANE SYNTHASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIARRHYTHMIC ACTIVITY; ARTICLE; DOG; DOSE RESPONSE; DRUG EFFECT; ENZYME INHIBITION; FEMALE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; HEART VENTRICLE FIBRILLATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; THROMBOCYTE AGGREGATION INHIBITION;

6-KETOPROSTAGLANDIN F1 ALPHA; ANIMALS; ANTI-ARRHYTHMIA AGENTS; ARRHYTHMIA; CYCLOOXYGENASE INHIBITORS; DISOPYRAMIDE; DOGS; ENZYME INHIBITORS; FEMALE; HUMANS; MALE; METHACRYLATES; MEXILETINE; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; PLATELET AGGREGATION; PYRIDINES; THROMBOXANE A2; THROMBOXANE-A SYNTHASE;

EID: 0030427020     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

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