Interleukin-1β induces nuclear factor κB in epithelial cells independently of the production of reactive oxygen intermediates

European Journal of Biochemistry

Volumn 242, Issue 3, 1996, Pages 544-549

  Bonizzi, Giuseppina ^a   Dejardin, Emmanuel ^a   Piret, Bernard ^a   Piette, Jacques ^a   Merville, Marie Paule ^a   Bours, Vincent ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Interleukin 1; Nuclear factor B; Oxidative stress; Signal transduction

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; REACTIVE OXYGEN METABOLITE;

ARTICLE; CELL TRANSFORMATION; CONTROLLED STUDY; EPITHELIUM CELL; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN INDUCTION; SIGNAL TRANSDUCTION;

EID: 0030425975     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1996.0544r.x     Document Type: Article

References (43)

1. Baeuerle, P. A. & Henkel, T. (1994) Function and activation of NF-κB in the immune system, Annu. Rev. Immunol. 12, 141-179.
2. Siebenlist, U., Franzoso, G. & Brown, K. (1994) Structure, regulation, and function of NF-κB, Annu. Rev. Biol. 10, 405-455.
3. Miyamoto, S. & Verma, I. M. (1995) Rel/NF-κB/lKB story, Adv. Cancer Res. 66, 255-292.
4. Beg, A. A. & Baldwin, A. S. (1993) The IκB proteins: multifunctional regulators of Rel/NF-κB transcription factors, Genes & Dev. 7, 2064-2070.
5. Haskill, S., Beg, A. A., Tompkins, S. M., Morris, J. S., Yurochko, A. D., Sampson-Johannes, A., Mondal, K., Ralph, P. & Baldwin, A. S. J. (1991) Characteriaation of an immediate-early gene induced in adherent monocyles that encodes I kappa B-like activity. Cell 65, 1281-1289.
6. Mercurio, F., DiDonato, J. A., Rosette, C. & Karin, M. (1993) p105 and p98 precursor proteins play an active role in NF-κB-mediated signal transduction, Genes & Dev. 7, 705-718.
7. Rice, N. R., MacKichan, M. L. & Israël, A. (1992) The precursor of NF-κB p50 has IκB-like functions, Cell 71, 243-253.
8. Thompson, J. E., Phillips, R. J., Erdjument-Bromage, H., Tempst, P. & Ghosh, S. (1995) Iκ-B-β regulates the persistent response in a biphasic activation of NF-κB, Cell 80, 573-582.
9. Bours, V., Franzoso, G., Azarenko, V., Park, S., Kanno, T., Brown, K. & Siebenlist, U. (1993) The oncoprotein Bcl-3 directly transactivates through κB motifs via association with DNA-binding p50B homodimers, Cell 72, 729-739.
10. Franzoso, G., Bours, V., Park, S., Tomita-Yumaguchi, M., Kelly, K. & Siebenlist, U. (1992) The candidate oncoprotein Bcl-3 is an antagonist of p50/NF-κB-mediated inhibition, Nature 359, 339-342.
11. Nolan, G. P., Fujita, T., Bhatia, K., Huppi, C., Liou, H.-C., Scott, M. L. & Baltimore. D. (1993) The bcl-3 proto-oncogene encodes a nuclear IκB-like molecule that preferentially interacts with NF-κB p50 and p52 in a phosphorylation-dependent manner, Mol. Cell. Biol. 13, 3557-3566.
12. Ohno, H., Takimoto, G. & .McKeithan, T. W. (1990) The candidate proto-oncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control, Cell 60, 991-997.
13. Anisowicz, A., Messineo, M., Lee, S. W. & Sager, R. (1991) An NF-kappa B-like transcription factor mediates IL,-1/TNF-alpha induction of gro in human fibroblasts, J. Immunol. 147, 250-257
14. Duh, E. J., Maury, W. J., Folks, T. M., Fauci, A. S. & Rabson, A B. (1989) Tumor necrosis factor a activates human immunodeficiency virus type 1 through induction of nuclear factor binding to the NF-κB sites in the long terminal repeat, Proc. Natl Acad. Sci USA 86, 5974-5978.
15. Lowenthal, J. W., Ballard, D. W., Bogerd, H., Böhnlein, H. & Greene, W. C. (1989). Tumor necrosis factor-α activation of the IL-2 receptor-a involves the induction of kB-specifie DNA binding proteins, J. Immunol. 142, 3121-3128.
16. Osborn, L., Kunkel, S. & Nabel, G. J. (1989) Tumor necrosis factor α and Interleukine 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor κB, Proc. Natl Acad. Sci. USA 86, 2336-2340.
17. Beg, A. A., Finco, T. S., Nantermet, P. V. & Baldwin, A. S. J. (1993) Tumor necrosis factor and interleukine-1 lead to phosphorylation and loss of IκBa: a mechanism for NF-κB activation, Mol. Cell Biol. 13, 3301-3310.
18. Brown, K., Park, S., Kanno, T., Franzoso, G. & Sibenlist, U. (1993) Mutual regulation of the transcriptional activator NF-κB and its inhibitor, IκB-α, Proc. Natl Acad. Sci. USA 90, 2532-2536.
19. Brown, K., Gerstberger, S., Carlson, L., Franzoso, G. & Siebenlist, U. (1995) Control of IκB-α proteolysis by site-specific, signalinduced phosphorylation, Science 267, 1485-1488.
20. Palombella, V. J., Rando, O. J., Goldberg, A. L. & Maniatis, T. (1994) The ubiquitin-proteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB, Cell 78, 77-85.
21. Traenckner, E. B.-M., Wilk, S. & Baeuerle, P. A. (1994) A proteasome inhibitor prevents activation of NF-κB and stabilizes a newly phosphorylated form of IκB-α that is still bound to NF-κB, EMBO J. 13, 5433-5441.
22. Traenckner, E. B.-M., Pahl, H. L., Henkel, T., Schmidt, K. N., Wilk, S. & Baeuerle, P. A. (1995) Phosphorylation of IκB-α on serines 32 and 36 controls IκB-α proteolysis and NF-κB activation in response to diverse stimuli, EMBO J. 14, 2876-2883.
23. Schreck, R., Rieber, P. & Baeuerle, P. A. (1991) Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1, EMBO J. 10, 2247-2258.
24. Schreck, R., Meier, B., Mannel, D. N., Droge, W. & Baeuerle, P. A. (1992) Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells, J. Exp. Med. 175, 1181-1194.
25. Brennan, P. & O'Neill, L. A. J. (1995) Effects of oxidants and anti-oxidants on nuclear factor κB activation in three different cell lines: evidence against a universal hypothesis involving oxygen radicals, Biochim. Biophys. Acta 1260, 167-175.
26. Dejardin, E., Bonizzi, G., Bellahcène, A., Castronovo, V., Merville, M.-P. & Bours, V. (1995) Highly-expressed p100/p52 (NFKB2) sequesters other NF-κB-related proteins in the cytoplasm of human breast cancer cells, Oncogene 11, 1835-1841.
27. 2 in cultured endothelial cells, Arch. Biochem. Biophys. 302, 348-355.
28. Bours, V., Dejardin, E., Goujon-Letawe, F., Merville, M.-P. & Castronovo, V. (1994) The NF-κB transcription factor and cancer: high expression of NF-κB and IκB-related proteins in tumor cell lines, Biochem. Pharmacol. 47, 145-149.
29. Kilian, P. L., Kaffka, K. L., Biondi, D. A., Lipman, J. M., Benjamin, W. R., Feldman, D. & Campen, C. A. (1991) Antiproliferative effect of interleukine-1 on human ovarian carcinoma cell line (NIH: OVCAR-3), Cancer Res. 51, 1823-1828.
30. Naumann, M. & Scheidereit, C. (1994) Activation of NF-κB in vivo is regulated by multiple phosphorylations, EMBO J. 13, 4597-607.
31. Ballou, L. R., Chao, C. P., Holness, M. A., Barker, S. C. & Ragshow, R. (1992) Interleukin-1-mediated PGE2 production and sphingomyelin metabolism, J. Biol. Chem. 267, 20044-20050.
32. Kolesnick, R. & Golde, D. W. (1994) The sphingomyelin pathway in tumor necrosis factor and Interleukine-1 signaling, Cell 77, 325-328.
33. Sandstrom, P. A., Roberts, B., Folks, T. M. & Buttke, T. M. (1993) HIV gene expression enhances T cell susceptibility to hydrogen peroxide-induced apoptosis, AIDS Res. Hum. Retrov. 9, 1107-1113.
34. Ray, K. P. & Kennard, N. (1993) Interleukin-1 induces a nuclear form of transcription factor NF-κB in human lung epithelial cells, Agents Actions 38, C61-C63.
35. Los, M., Schenk, H., Hexel, K., Baeuerle, P. A., Dröge, W. & Schulze-Osthoff, K. (1995) IL-2 gene expression and NF-κB activation through CD28 requires reactive oxygen production by 5-lipoxygenase, EMBO J. 14, 3731-3740.
36. Schütze, S., Potthoff, K., Machleidt, T., Berkovic, D., Wiegmann, K. & Krönke, M. (1992) TNF activates NF-κB by phosphatidylcholine-specific phopholipase C-induced 'acidic' sphingomyelin breakdown, Cell 71, 765-776.
37. Wiegmann, K., Schütze, S., Machleidt, T., Witte, D. & Krönke, M. (1994) Functional dichotomy of neutral and acidic sphingomy-elinases in tumor necrosis factor signaling, Cell 78, 1005-1015.
38. Stylianou, E., O'Neill, L. A. J., Rawlinson, L., Edbrooker, M. R., Woo, P. & Saklatvala, J. (1992) Interleukin 1 induces NF-κB through its type I but not its type II receptor in lyphocytes, J. Biol. Chem. 267, 15836-15841.
39. Moynagh, P. N., Williams, D. C., O'Neill, L. A. J. (1994) Activation of NF-κB and induction of vascular cell adhesion molecule-1 and intracellular adhesion molecule-1 expression in human glial cells by IL-1, J. Immunol. 153, 2681-2690.
40. Oppenheim, J. J., Kovacs, E. J., Matsushima, K. & Durum, S. K. (1986) There is more than one interleukin 1, Immunol. Today 7, 45-56.
41. Kang, S. M., Tran, A. C., Grilli, M. & Lenardo, M. J. (1992) NF-kappa B subunit regulation in nontransformed CD4+ T lymphocytes, Science 256, 1452-1456.
42. Kunsch, C., Ruben, S. M. & Rosen, C. A. (1992) Selection of optimal kB/Rel DNA-binding motifs: interaction of both subunits of NF-κB with DNA is required for transcriptionnal activation, Mol. Cell. Biol. 12, 4412-4421.
43. Miyamoto, S., Schmitt, M. J. & Verma, I. M. (1994) Qualitative changes in the subunit composition of κB-binding complexes during murine B-cell differentiation, Proc. Natl Acad. Sci. 91 USA, 5056-5060.