Structural model for the selenocysteine-specific elongation factor SelB

Biochimie

Volumn 78, Issue 11-12, 1996, Pages 971-978

  Hilgenfeld, R ^a   Bock A ^b   Wilting, R ^b  

^a FRITZ LIPMANN INSTITUTE   (Germany)

^b Lehrstuhl fur Mikrobiologie   (Germany)

Author keywords

Elongation factor; Prokaryotes; Protein synthesis; Selenocysteine; tRNA

Indexed keywords

ELONGATION FACTOR; EPITOPE; GUANINE NUCLEOTIDE; GUANOSINE TRIPHOSPHATE; INITIATION FACTOR 2; SELENOCYSTEINE; TRANSFER RNA;

AMINO TERMINAL SEQUENCE; BINDING SITE; CONFERENCE PAPER; CONSENSUS SEQUENCE; CONTROLLED STUDY; DRUG HYDROLYSIS; ESCHERICHIA COLI; NONHUMAN; PHYLOGENY; PROKARYOTE; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; THERMUS THERMOPHILUS; TRANSLATION REGULATION;

ESCHERICHIA COLI; PROKARYOTA; THERMUS THERMOPHILUS;

EID: 0030425121     PISSN: 03009084     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-9084(97)86719-3     Document Type: Conference Paper

References (23)

1. 1 Baron C, Böck A (1995) The selenocysteine-inserting tRNA species: Structure and function. In: tRNA: Structure, Biosynthesis and Function (Söll D, RhajBhandary U, eds) American Society for Microbiology, ASM Press, Washington DC, 529-544
2. 2 Heider J, Baron C, Böck A (1992) Coding from a distance: dissection of the mRNA determinants required for the incorporation of selenocysteine into protein. EMBO J 11, 3759-3766
3. 3 Baron C, Heider J, Böck A (1993) Interaction of translation factor SelB with the formate dehydrogenase selenopolypeptide mRNA. Proc Natl Acad Sci USA 90, 4181-4185
4. 4 Ringquist S, Schneider P, Gibson T, Baron C, Böck A, Gold L (1994) Recognition of the mRNA selenocysteine insertion sequences by the specialized translation factor SelB. Genes Dev 8, 376-385
5. 5 Tormay P, Sawers A, Böck A (1996) Role of the stoichiometry between mRNA, translation factor SelB and selenocysteyl-tRNA in selenoprotein synthesis. Mol Microbiol 21, 1253-1259
6. 6 Kromayer M, Wilting R, Tormay P, Böck A (1996) Domain structure of the prokaryotic selenocysteine-specific elongation factor SelB. J Mol Biol 262, 413-420
7. 7 Forchhammer K, Leinfelder W, Böck A (1989) Identification of a novel translation factor necessary for incorporation of selenocysteine into protein. Nature (Lond) 342, 453-456
8. 8 Förster C, Ott G, Forchhammer K, Sprinzl M (1990) Interaction of selenocysteine-incorporating tRNA with elongation factor Tu from E coli. Nucleic Acids Res 18, 487-491
9. 9 Berchtold H, Reshetnikova L, Reiser CO, Schirmer NK, Sprinzl M, Hilgenfeld R (1993) Crystal structure of active elongation factor Tu reveals major domain rearrangements. Nature 365, 126-132
10. 10 Jones TA (1985) Interactive computer graphics: FRODO. Methods Enzymol 115, 157-171
11. 11 Hermans J, McQueen JE (1974) Computer manipulation of (macro) molecules with the method of local exchange. Acta Crystallogr Sect A 30, 730
12. 12 Summers NL, Karplus M (1989) Construction of side-chains in homology modelling. Application to the c-terminal lobe of rhizopuspepsin. J Mol Biol 210, 785-811.
13. 13 Kjeldgaard M, Nissen P, Thirup S, Nyborg J (1993) The crystal structure of elongation factor Tu from Thermus aquaticus in the GTP conformation. Structure 1, 35-50
14. 14 Kjeldgaard M, Nyborg J (1992) Refined structure of elongation factor EF-Tu from Escherichia coli. J Mol Biol 223, 721-742
15. 15 Forchhammer K, Rücknagel K-P Böck A (1990) Purification and biochemical characterisation of SelB, a translation factor involved in selenoprotein synthesis. J Biol Chem 265, 9346-9350
16. 16 Peter ME, Schirmer NU, Reiser COA Sprinzl M (1990) Mapping of the effector region in Thermus thermophilus EF-Tu. Biochemistry 29, 2876-2884
17. 17 Hilgenfeld R (1995) How do GTPases really work? Nature Struct Biol 2, 3-6
18. 18 Kawashima T, Berthet-Colominas C, Wulff M, Cusack S, Leberman R (1996) The structure of Escherichia coli EF-Tu. EF-Ts complex at 2.5 Å resolution. Nature 379, 511-518
19. Phe, EF-Tu and a GTP analog. Science 270, 1464-1472
20. 20 Olsen GJ, Woese CR, Overbeck R (1994) The winds of (evolutionary) changes: Breathing new life into microbiology. J Bacteriol 176, 1-6
21. 21 Fleischmann RD, Adams MD, White O, et al (1995) The genome of Haemophilus influenzae Rd. Science 269, 496-512
22. 22 Baron C, Böck A (1991) The lengh of the aminoacyl-acceptor stem of selenocysteine-specific tRNA of Escherichia coli is the determinant for binding to elongation factors SelB or EF-Tu. J Biol Chem 266, 20375-20379
23. 23 Tormay P, Böck A (1997) Barriers for the heterologous expression of a selenoprotein gene in bacteria. J Bacteriol 179, 576-582