Dansylated octapeptide Dns-Glu-Asp-Asp-Ser-Asp-Glu-Glu-Asn inhibits the proliferation rate of HL-60 cells

Canadian Journal of Physiology and Pharmacology

Volumn 74, Issue 12, 1996, Pages 1302-1307

  Marsili, Valeria ^a   Nardicchi, Vincenza ^a   Lupidi, Giulio ^b   Brozzetti, Annalisa ^a   Gianfranceschi, Gian Luigi ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

^b UNIVERSITY OF CAMERINO   (Italy)

Author keywords

Cell proliferation; Chromatin peptides; HL 60 cells; Membrane permeability; Peptide internalization

Indexed keywords

OCTAPEPTIDE;

ARTICLE; CELL CULTURE; CELL LINE; CELL PROLIFERATION; CELL STRAIN HL 60; CHROMATIN; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; HUMAN; HUMAN CELL; HYDROPHOBICITY; MEMBRANE PERMEABILITY; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION;

EID: 0030424748     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/y96-133     Document Type: Article

References (15)

1. Angiolillo, A., Lupidi, G., Qualadrucci, P., and Gianfranceschi, G.L. 1992. Dansylation of small acidic peptides and interaction with DNA-histone complex. Med. Sci. Res. 21: 149-150.
2. Angiolillo, A., Bramucci, M., Marsili, V., Panara, F., Miano, A., Amici, D., and Gianfranceschi, G.L. 1993a. Phosphorylation of synthetic acidic peptides by casein kinase II: evidence for competition with phosphorylation of proteins involved in transcription. Mol. Cell. Biochem. 125: 65-72.
3. Angiolillo, A., Desgro, A., Marsili, V., Panara, F., and Gianfranceschi, G.L. 1993b. Synthetic octapeptide pyroGlu-Asp-Asp-Ser-Asp-Glu-Glu-Asn controls DNA transcription in vitro by RNA polymerase II. Experientia, 49: 902-905.
4. Boraschi, D., Ghiara, P., Scapigliati, G., Villa, L., Sette, A., and Tagliabue, A. 1992. Binding and internalization of 163-171 fragment of human IL-1β. Cytokine, 4: 201-204.
5. Castigli, E., Mancinelli, L., Mariggiò, M.A., and Gianfranceschi, G.L. 1993. Possible activation of RNA synthesis in PC12 cells isolated nuclei by small acidic peptides. Am. J. Physiol. 265: C1220-C1223.
6. Gianfranceschi, G.L., Barra, D., Bossa, F., Coderoni, S., Paparelli, M., Venanzi, F., Cicconi, F., and Amici, D. 1982. Small peptides controlling transcription in vitro are bound to chromatin DNA. Biochim. Biophys. Acta, 699: 138-148.
7. Gianfranceschi, G.L., Czerwinski, A., Angiolillo, A., Marsili, V., Castigli, E., Mancinelli, L., Miano, A., Bramucci, M., and Amici, D. 1994. Molecular models of small phosphorylated chromatin peptides. Structure-function relationship and regulatory activity on in vitro transcription and on cell growth and differentiation. Peptides, 15:7-13.
8. Grokhovskii, S.L., Surovaya, A.N., and Sidorova, N.Y. 1988. Design and synthesis of peptides capable of binding specifically to DNA. Mol. Biol. 22: 1056-1072.
9. Humphrey, M.J., and Ringrose, P.S. 1986. Peptides and related drugs: a review of their absorption, metabolism and excretion. Drug Metab. Rev. 17: 283-289.
10. Krebs, K.G., Heusser, D., and Wimmer, H. 1969. Spray reagent. In Thin layer chromatography. Edited by E. Stahl. Springer Verlag, Berlin, Heidelberg, New York. pp. 854-905.
11. Lin, Y.Z., Yao, S.Y., Veach, R.A., Torgenson, T.R., and Hawiger, J. 1995. Inhibition of nuclear translocation of transcription factor NF-kB by a synthetic peptide containing a cell membrane permeable motif and nuclear localization sequence. J. Biol. Chem. 270(24): 14 255-14 258.
12. Lyman, G.A., and Preisler, H.D. 1976. Membrane action of DMSO and other chemical inducer of Friend leukemic cell differentiation. Nature (London), 262: 360-363.
13. Manley, H.L., Fire, A., Cano, A., Sharp, P.A., and Gefter, M.L. 1980. DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract. Proc. Natl. Acad. Sci. U.S.A. 77: 3855-3859.
14. Marsili, V., Angiolillo, A., and Gianfranceschi, G.L. 1995. Synthetic octapeptide pyroGlu-Asp-Asp-Ser-Asp-Glu-Glu-Asn promotes differentiation in promyelocytic cell line. Cell. Mol. Biol. 41(4): 515-523.
15. Presentini, R., Prin, F., Ancilli, G., Bartalini, M., Nucci, D., Villa, L., Boraschi, D., and Antoni, G. 1990. Radiolabelling of the biologically active peptide 163-171 of human interleukin 1β. Appl. Radiat. Isot. 41: 696-699.