κ-opioid agonist, U50,488H, stimulates ovine fetal pituitary-adrenal function via hypothalamic arginine-vasopressin and corticotrophin-releasing factor

Journal of Pharmacology and Experimental Therapeutics

Volumn 277, Issue 2, 1996, Pages 877-884

  Taylor, Cindy C ^a   Wu, Dunli ^a   Soong, Y I ^a   Yee, Jenny S ^a   Szeto, Hazel H ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE METHANESULFONATE; CORTICOTROPIN; HYDROCORTISONE; KAPPA OPIATE RECEPTOR AGONIST; NALOXONE; OPIATE ANTAGONIST;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORTICOTROPIN BLOOD LEVEL; FETUS BLOOD; HYDROCORTISONE BLOOD LEVEL; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; OBSTETRIC ANALGESIA; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL;

3,4-DICHLORO-N-METHYL-N-(2-(1-PYRROLIDINYL)-CYCLOHEXYL)-BENZENEACETAMIDE, (TRANS)-ISOMER; ADRENOCORTICOTROPIC HORMONE; ANALGESICS; ANIMALS; ARGININE VASOPRESSIN; CORTICOTROPIN-RELEASING HORMONE; FEMALE; HYDROCORTISONE; HYPOTHALAMUS; NALOXONE; PITUITARY-ADRENAL SYSTEM; PREGNANCY; PYRROLIDINES; RECEPTORS, OPIOID, KAPPA; SHEEP;

EID: 0030424475     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. ADAMSON, W. T., WINDH, R. T., BLACKFORD, S. AND KUHN, C. M.: Ontogeny of muand kappa-opiate receptor control of the hypothalamo-pituitary-adrenal axis in rats. Endocrinology 129: 959-964, 1991.
2. AKAGI, K., BERDUSCO, E. T. AND CHALLIS, J. R. G.: Cortisol inhibits ACTH but not the AVP response to hypoxaemia in fetal lambs at days 123-128 of gestation. J. Dev. Physiol. 14: 319-324, 1990.
3. ANTONI, F. A.: Vasopressinergic control of pituitary adrenocorticotropin secretion comes of age. Frontiers Neuroendocrinol. 14: 76-122, 1993.
4. APOSTOLAKIS, E. M., LONGO, L. D. AND YELLON, S. M.: Regulation of basal adrenocorticotropin and cortisol secretion by arginine vasopressin in the fetal sheep during late gestation. Endocrinology 129: 295-300, 1991.
5. BENNET, L., JOHNSTON, B M , VALE, W. W. AND GLUCKMAN, P. D.: The effects of corticotrophin-releasing factor and two antagonists on breathing movements in fetal sheep. J. Physiol. 421: 1-11, 1990.
6. BERO, L. A., LURIE, S. N. AND KUHN, C. M.: Early ontogeny of kappa-opioid receptor regulation of prolactin secretion in the rat. Brain Res. 465: 189-196, 1987.
7. BISSONNETTE, J. M , HOHIMER, A. R. AND RICHARDSON, B. S.: Ventriculocisternal cerebrospinal perfusion in unanesthetized fetal lambs. J. Appl. Physiol. 50: 880-883, 1981.
8. BOUSQUET, J., LYE, S. J. AND CHALLIS, J. R. G.: Comparison of leucine enkephalin and adrenocorticotrophin effects on adrenal function in fetal and adult sheep. J. Reprod. Fert. 70: 499-506, 1984.
9. BROOKS, A. N. AND CHALLIS, J. R. G.: Exogenous opioid regulation of the hypothalamic-pituitary-adrenal axis in fetal sheep. J. Endocrinol. 119: 389-395, 1988.
10. BROOKS, A. N. AND CHALLIS, J. R. G.: Effects of CRF, AVP and opioid peptides on pituitary-adrenal responses in sheep Peptides 10: 1291-1293, 1989.
11. BROOKS, A. N. AND CHALLIS, J R. G.: Adrenocorticotrophin responses to hypoxaemia in fetal sheep are sustained in the presence of naloxone. J. Dev. Physiol. 1992.
12. BROOKS, A. N. AND GIBSON, F.: ProstagLandin E2 enhances AVP-stiraulated but not CRF-stimulated ACTH secretion from cultured fetal sheep pituitary cells. J. Endocrinol. 132: 33-38, 1992.
13. BUCKINGHAM, J. C. AND COOPER, T. A.: Pharmalogical characterization of opioid receptors influencing the secretion of corticotrophin releasing factor in the rat. Neuroendocrinology 44: 36-40, 1986.
14. CURRIE, I. S. AND BROOKS, A. N.: Corticotrophin-releasing factors in the hypothalamus of the developing fetal sheep. J. Dev. Physiol. 17: 241-246, 1992.
15. DUNLAP, C. E AND VALEGO, N. K.: Cardiovascular effects of dynorphin A-(1-13) and arginine vasopressin in fetal lambs Am. J. Physiol. 256: R1318-R1324, 1989.
16. ENGLER, D , PHAM, T., FULLERTON, M. J., OOI, G., FUNDER, J. W. AND CLARKE, I J.: Studies of the secretion of corticotropin-releasing factor and arginine vasopressin into the hypophysial-portal circulation of the conscious sheep. Neuroendocrinology 49: 367-381, 1989
17. FAMILARI, M., SMITH, A. I., SMITH, R. AND FUNDER, J. W.: Arginine vasopressin is a much more potent stimulus to ACTH release from ovine anterior pituitary cells than ovine corticotropin-releasing factor. Neuroendocrinology 50: 152-157, 1989.
18. GILLIES, G. E., LINTON, E. A. AND LOWRY, P. J.: Corticotropin releasing activity of the new CRF is potentiated several times by vasopressin. Nature 299: 355-357, 1982.
19. HORAN, P., TAYLOR, J., YAMAMURA, H I. AND PORRECA, F.: Extremely long-lasting antagonistic actions of nor-binaltorphimine (nor-BNI) in the mouse tail-flick test. J. Pharmacol. Exp. Ther. 260: 1237-1243, 1992.
20. IYENGAR, S., KIM, H. S. AND WOOD, P. L.: Kappa opiate agonists modulate the hypothalamic-pituitary-adrenal axis in the rat. J. Pharmacol. Exp. Ther. 238: 429-436, 1986.
21. IYENGAR, S., KIM, S. H. AND WOOD, P. L.: Mu-, delta-, kappa- and epsilon-opioid receptor modulation of the hypothalamic-pituitary-adrenocorticoal (HPA) axis: Subchronic tolerance studies of endogenous opioid peptides. Brain Res. 435: 220-226, 1987.
22. JOUBERT, D. M.: A study of pre-natal growth and development in the sheep. J. Agric. Sci. 47: 382-427, 1956.
23. MAGYAR, D. M., FRIDSHAL, D., ELSNER, C. W., GLATZ, T., ELIOT, J., KLEIN, A. H., LOWE, K. C., BUSTER, J. E. AND NATHANIELSZ, P. W.: Time-trend analysis of plasma cortisol concentrations in the fetal sheep in relation to parturition. Endocrinology 107: 155-159, 1980.
24. MANSOUR, A., FOX, C. A., AKIL, H. AND WATSON, S. J.: Opioid-receptor mRNA expression in the rat CNS: Anatomical and functional implications. Trends Neurosci. 18: 22-29, 1995.
25. MCKAY, E. M.: The relation of acquired morphine tolerance to the adrenal cortex. J. Pharmacol. 43: 51-60, 1931.
26. NIKOLARAKIS, K. E., ALMEIDA, O. F. X., SIRINATHSIGNHJI, D. J. S. AND HERZ, A.: Concomitant changes in the in vitro and in vivo release of opioid peptides and luteinizing hormone-releasing hormone from the hypothalamus following blockade of receptors for corticotrophin-releasing factor. Neuroendocrinology 47: 545-550, 1988.
27. NORMAN, L. J. AND CHALLIS, J. R. G.: Synergism between systemic corticotropin-releasing factor and arginine vasopressin on adrenocorticotropin release in vivo varies as a function of gestational age in the ovine fetus. Endocrinology 120: 1052-1058, 1987.
28. OISO, Y., IWASAKI, Y., KONDO, K, TAKATSUKI, K. AND TOMITA, A.: Effect of the opioid kappa-receptor agonist U50488H on the secretion of arginine vasopressin. Neuroendocrinology 48: 658-662, 1988.
29. PARROTT, K. F. AND GOODE, J. A.: Central effects of naloxone and selected opioid agonists on cortisol and prolactin secretion in non-stressed sheep. Gen. Pharmac. 24: 101-103, 1993.
30. PECHNICK, R. N.: Effects of opioids on the hypothalamo-pituitary-adrenal axis. Annu. Rev. Pharmacol. Toxicol. 33: 353-382, 1993.
31. PFEIFFER, A., HERZ, A., LORIAUX, D. L. AND PFEIFFER, D. G.: Central kappa- and mu-opiate receptors mediate ACTH-release in rats. Endocrinology 116: 2688-2690, 1985.
32. REDEKOPP, C. A., LIVESEY, J. H. AND DONALD, R. A.: Inhibition of spontaneous ACTH release and improved response to CRF in sheep premedicated with the enkephalin analogue DAMME. Horm. Metabol. Res. 17: 646-649, 1985.
33. REISINE, T. AND BROWNSTEIN, M. J.: Opioid and cannabinoid receptors. Curr. Opin. Neurobiol. 4: 406-412, 1994.
34. RIVIER, C. AND VALE, W.: Interaction of corticotropin-releasing factor and arginine vasopressin on adrenocorticotropin secretion in vivo. Endocrinology 11: 939-942, 1983.
35. ROSE, J. C., MEIS, J. P. AND MORRIS, M.: Ontogeny of endocrine (ACTH, vasopressin, cortisol) responses to hypotension in lamb fetuses. Am. J. Physiol. 240: 656-662, 1981.
36. ROTH, K. A., WEBER, E., BARCHAS, J. D., CHANG, D. AND CHANG, J.-K.: Immunoreactive dynorphin-(1-8) and corticotropin-releasing factor in subpopulation of hypothalamic neurons. Science 219: 189-191, 1983.
37. SHEN, P. J., CLARKE, I. J., CANNY, B. J., FUNDER, J. W. AND SMITH, A. I.: Arginine vasopressin and corticotropin releasing factor: Binding to ovine anterior pituitary membranes. Endocrinology 127: 2085-2089, 1990.
38. SZETO, H. H.: Effects of narcotic drugs on fetal behavioral activity: Acute methadone exposure. Am. J. Obstet. Gynecol. 146: 211-217, 1983.
39. SZETO, H. H., WU, D. L., CHENG, P. Y., SOONG, Y., TAYLOR, C. C. AND YEE, J.: Cardiovascular and respiratory actions of U50, 488H in the unanesthetized ovine foetus. Eur. J. Pharmacol. 297: 77-82, 1996.
40. TAYLOR, C. C., SOONG, Y., WU, D. AND SZETO, H. H.: Differential effects of mu, delta, and kappa opioid agonists on fetal plasma cortisol levels. Reg. Pept. 54: 297-298, 1994.
41. TSAGARAKIS, S., REES, L. H., BESSER, M. AND GROSSMAN, A.: Opiate receptor subtype regulation of CRF-41 release from rat hypothalamus in vitro. Neuroendocrinology 51: 599-605, 1990.
42. WANG, X., TRESHAM, J. J., SCOGGINS, B. A. AND COGHLAN, J. P.: Met-enkephalin and the enkephalin analogue FK-33824 centrally inhibit adrenocorticotrophic hormone secretion in sheep. Clin. Exp. Pharm. Phys. 15: 865-873, 1988.
43. WANG, X. -M., COGHLAN, J. P., CONGIU, M., SCOGGINS, B. A. AND WINTOUR, E. M.: Met-enkephalin stimulates secretion of ACTH in sheep. J. Endocrinol. 111: 463-467, 1986.
44. WATSON, S. J., AKIL, H., FISCHLI, W., GOLDSTEIN, A., ZIMMERMAN, E., NILAVER, G. AND VAN WIMERSMA GREIDANUS, T. B.: Dynorphin and vasopressin: Common localization in magnocellular neurons. Science 216: 85-87, 1982.
45. WOOD, P. L., KIM, H. S., COSI, C. AND IYENGAR, S.: The endogenous kappa agonist, dynorphin (1-13), does not alter basal or morphine-stimulated dopamine metabolism in the nigrostriatal pathway of the rat. Neuropharmacology 26: 1585-1588, 1987.
46. YANG, K. P. AND CHALLIS, J. R. G.: Opioid receptors are present in the hypothalamus but not detectable in the anterior pituitary of the developing ovine fetus. Neuroendocrinology 53: 623-627, 1991.