Compared structures of the free nicotinic acetylcholine receptor main immunogenic region (MIR) decapeptide and the antibody-bound [A76] MIR analogue: A molecular dynamics simulation from two-dimensional NMR data

Biopolymers

Volumn 40, Issue 5, 1996, Pages 419-432

  Orlewski, Piotr ^a   Marraud, Michel ^b   Cung, Manh Thong ^a,b   Tsikaris, Vassilios ^c   Sakarellos Daitsiotis, Maria ^c   Sakarellos, Constantinos ^d   Vatzaki, Efstratia ^c   Tzartos, Socrates J ^b   Sons, Inc ^d  

^a LAB DE CHIM PHYS MACROMOLECULAIRE   (France)

^b UNIVERSITY OF IOANNINA   (Greece)

^c HELLENIC PASTEUR INSTITUTE   (Greece)

^d NONE

Author keywords

Acetylcholine receptor; Antigen antibody interaction; Antigenie peptide; Dmso solvent box; Molecular dynamics; Myasthenia gravis; Two dimensional nmr

Indexed keywords

ANTIBODIES; CALCULATIONS; COMPUTER SIMULATION; CONFORMATIONS; HYDROGEN BONDS; IMMUNOLOGY; MOLECULAR DYNAMICS; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ORGANIC COMPOUNDS; SOLVENTS;

DECAPEPTIDE; MAIN IMMUNOGENIC REGION; MYASTHENIA GRAVIS; NICOTINIC ACETYLCHOLINE RECEPTOR;

ANTIGEN-ANTIBODY REACTIONS;

NICOTINIC RECEPTOR;

ANIMAL EXPERIMENT; ANTIGEN ANTIBODY COMPLEX; ARTICLE; IMMUNOGENICITY; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MYASTHENIA GRAVIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PROTEIN STRUCTURE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGEN-ANTIBODY COMPLEX; COMPUTER SIMULATION; DIMETHYL SULFOXIDE; EPITOPES; HYDROGEN BONDING; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, NICOTINIC; TORPEDO;

ANIMALIA; TORPEDO CALIFORNICA;

EID: 0030424262     PISSN: 00063525     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0282(1996)40:5<419::AID-BIP1<3.0.CO;2-Z     Document Type: Article

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