Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. IV. Regulation by external Ca++ of α-bungarotoxin-sensitive receptor function and of rectification induced by internal Mg++

Journal of Pharmacology and Experimental Therapeutics

Volumn 277, Issue 1, 1996, Pages 432-444

  Bonfante Cabarcas, R ^a,b   Swanson, K L ^a   Alkondon, M ^a   Albuquerque, E X ^a,b  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ADENOSINE TRIPHOSPHATE; ALPHA BUNGAROTOXIN; CALCIUM; CALCIUM CHLORIDE; MAGNESIUM; NICOTINIC RECEPTOR;

ALPHA CHAIN; AMPLITUDE MODULATION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; DATA ANALYSIS; DESENSITIZATION; ENERGY; EXTRACELLULAR CALCIUM; HIPPOCAMPUS; NERVE CONDUCTION; NONHUMAN; OOCYTE; PATCH CLAMP; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; SYNAPTIC TRANSMISSION; TISSUE CULTURE;

ACETYLCHOLINE; ADAPTATION, PHYSIOLOGICAL; ANIMALS; BUNGAROTOXINS; CALCIUM; HIPPOCAMPUS; MAGNESIUM; NICOTINIC AGONISTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NICOTINIC;

EID: 0030424081     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. ADAMS, D. J. AND NUTTER, T. J.: Calcium permeability and modulation of nicotinic acetylcholine receptor-channels in rat parasympathetic neurons. J. Physiol. (Paris) 86: 67-76, 1992.
2. ALBUQUERQUE, E. X., DESHPANDE, S. S., ARACAVA, Y., ALKONDON, M. AND DALY, J. W.: A possible involvement of cyclic AMP in the expression of desensitization of the nicotinic acetylcholine receptor. FEBS Lett. 199: 113-120, 1986.
3. ALBUQUERQUE, E. X., PEREIRA, E. F. R., BONFANTE-CARBARCAS, R., MARCHIORO, M., MATSUBAYASHI, H., ALKONDON, M. AND MAELICKE, A.: Nicotinic acetylcholine receptors on hippocampal neurons: Cell-compartment specific expression and modulatory control of channel activity. Prog. Brain Res., in press, 1995a.
4. ALBUQUERQUE, E. X., PEREIRA, E. F. R., CASTRO, N. G. AND ALKONDON, M.: Neuronal nicotinic receptors: Function, modulation and structure. Semin. Neurosci. 7: 91-101, 1995b.
5. ALKONDON, M. AND ALBUQUERQUE, E. X.: Initial characterization of the nicotinic acetylcholine receptors in rat hippocampal neurons. J. Receptor Res. 11: 1001-1021, 1991.
6. ALKONDON, M. AND ALBUQUERQUE, E. X.: Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. I Pharmacological and functional evidence for distinct structural subtypes. J. Pharmacol. Exp. Ther. 265: 1455-1473, 1993.
7. ALKONDON, M., REINHARDT, S., LOBRON, C., HERMSEN, B., MAELICKE, A. AND ALBUQUERQUE, E. X.: Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. II. The rundown and inward rectification of agonist-elicited whole-cell currents and identification of receptor subunits by in situ hybridization. J. Pharmacol. Exp. Ther. 271: 494-506, 1994.
8. AMADOR, M. AND DANI, J. A.: Mechanism for modulation of nicotinic acetylcholine receptors that can influence synaptic transmission. J Neurosci. 15: 4525-1532, 1995.
9. ANAND, R., CONROY, W. G., SCHOEPFER, R., WHITING, P. AND LINDSTROM, J.: Neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes have a pentameric quaternary structure. J. Biol. Chem. 266: 11192-11198, 1991.
10. 2+ Soc. Neurosci. Abs. 21: 343, 1995.
11. CASTRO, N. G. AND ALBUQUERQUE, E. X.: Brief-lifetime, fast-inactivating ion channels account for the α-bungarotoxin-sensitive nicotinic response in hippocampal neurons. Neurosci. Lett. 164: 137-140, 1993.
12. CASTRO, N. G. AND ALBUQUERQUE, E. X.: α-Bungarotoxin-sensitive hippocampal nicotinic receptor channel has a high calcium permeability. Biophys. J. 68: 516-524, 1995.
13. CHANG, H. W. AND NEUMANN, E.: Dynamic properties of isolated acetylcholine receptor proteins: Release of calcium ions caused by acetylcholine binding. Proc. Natl. Acad Sci. U.S.A. 73: 3364-3368, 1976.
14. CHANGEUX, J.-P.: Functional architecture and dynamics of the nicotinic acetylcholine receptor: An allosteric ligand-gated ion channel. In Fidia Research Foundation Neuroscience Award Lectures, ed. by J.-P. Changeux, R. R. Llinás, D. Purves and F. E. Bloom, pp. 21-168, Raven Press, Ltd., New York, 1990.
15. COLQUHOUN, D. AND SAKMANN, B.: Fast events in single-channel currents activated by acetylcholine and its analogues at frog muscle endplate. J. Physiol. (Lond.) 369: 501-557, 1985.
16. COUTURIER, S., BERTRAND, D., MATTER, J. M., HEHNANDEZ, M. C., BERTRAND, S., MILLAR, N., VALERA, M., BARKAS, T. AND BALLIVET, M.: A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX. Neuron 5: 847-856, 1990.
17. DAWSON, R. M. C., ELLIOT, D. C., ELLIOT, W. H. AND JONES, K. M.: Data for Biochemical Research, Clarendon Press, Oxford, 1986.
18. EISELE, J.-L., BERTRAND, S., GALZI, J.-L., DEVILLESS-THIERY, A., CHANGEUX, J.-P. AND BERTRAND, S.: Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities. Nature (Lond.) 366: 479-483, 1993.
19. ELDEFRAWI, M. E., ELDEFRAWI, A. T., PENFIELD, L. A., O'BRIEN, R. D. AND VAN CAMPEN, D.: Binding of calcium and zinc to the acetylcholine receptor purified from Torpedo californica. Life Sci. 16: 925-936, 1975.
20. FORSTER, I. AND BERTRAND, D.: Inward rectification of neuronal nicotinic acetylcholine receptors investigated by using the homomeric α7 receptor. Proc. R. Soc. Lond. B Biol. Sci. 260: 139-148, 1995.
21. GIRAULT, J. A.: Protein phosphorylation and dephosphorylation in mammalian central nervous system. Neurochem. Int. 23: 1-25, 1993.
22. GROSS, A., BALLIVET, M., RUNGGER, D. AND BERTRAND, D.: Neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes: Role of the α subunit in agonist sensitivity and desensitization. Pflügers Arch. 419: 545-551, 1991.
23. HAMILL, O. P., MARTY, A., NEHER, E., SARMANN, B. AND SIGWORTH, F. J.: Improved patch-clamp techniques for high resolution currents recordings from cells and cell-free membrane patches. Pflügers Arch. 391: 85-100, 1981.
24. HARDWICK, J. C. AND PARSONS, R. L.: Mechanism of staurosporine-induced decrease in acetylcholine receptor recovery from desensitization. Br. J. Pharmacol. 108: 741-748, 1993a.
25. HARDWICK, J. C. AND PARSONS, R. L.: Necessity of divalent cations for recovery from carbachol-induced nicotinic acetylcholine receptor inactivation at snake twitch fibre endplate. Br. J. Pharmacol. 110: 889-895, 1993b.
26. HUGANIR, R. L., DELCOUR, A. H., GREENGARD, P. AND HESS, G. P.: Phosphorylation of the nicotinic acetylcholine receptor regulates its rate of desensitization. Nature (Lond.) 321: 774-776, 1986.
27. IFUNE, C. K. AND STEINBACH, J. H.: Voltage-dependent block by magnesium of neuronal nicotinic acetylcholine receptor channels in rat phaeochromocytoma cells. J. Physiol. (Lond.) 443: 683-701, 1991.
28. IFUNE, C. K. AND STEINBACH, J. H.: Inward rectification of acetylcholine-elicited currents in rat phaeochromocytoma cells. J. Physiol. (Lond.) 457: 143-165, 1992.
29. ISHIHARA, K., ALKONDON, M., MONTES, J. G. AND ALBUQUERQUE, E. X.: Nicotinic responses in acutely dissociated rat hippocampal neurons and the selective blockade of fast-desensitizing nicotinic currents by lead. J. Pharmacol. Exp. Ther. 273: 1471-1482, 1995.
30. JACKSON, M. B.: Kinetics of unliganded acetylcholine receptor channel gating. Biophys. J. 49: 663-672, 1986.
31. KARLIN, A.: Structure of nicotinic acetylcholine receptors. Curr. Opin. Neurobiol. 3: 299-309, 1993.
32. KAY, A. R.: An intracellular medium formulary. J. Neurosci. Methods 44: 91-100, 1992.
33. LINDSTROM, J.: Nicotinic acetylcholine receptor. In Handbook of Receptors and Channels, ed. by R. Alan North, pp. 153-175, CRC Press, Ann Arbor, 1995.
34. MATHIE, A., COLQUHOUN, D. AND CULL-CANDY, S. G.: Rectification of currents activated by nicotinic acetylcholine receptors in rat sympathetic ganglion neurones. J. PhysioJ. (Lond.) 394: 501-527, 1989.
35. MCGEHEE, D. S. AND ROLE, L. W.: Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons. Ann. Rev. Physiol. 57: 521-546, 1995.
36. MULLE, C., LÉNA, C. AND CHANGEUX, J.-P.: Potentiation of nicotinic receptor response by external calcium in rat central neurons. Neuron 8: 937-945, 1992.
37. MULLE, C., VIDAL, C., BENOIT, P. AND CHANGEUX, J.-P.: Existence of different subtypes of nicotinic aeetylcholine receptors in the rat habenulointerpeduncular system. J. Neurosci. 11: 2588-2597, 1991.
38. PENG, X., KATZ, M., GERZANICH, V., ANAND, R. AND LINDSTROM, J.: Human α7 acetylcholine receptor: Cloning of the α7 subunit from the SH-SY5Y cell line and determination of pharmacological properties of native receptors and functional α7 homomer expressed in Xenopus oocytes. Mol. Pharmacol. 45: 546-554, 1994.
39. PEREIRA, E. F. R., ARACAVA, Y., ARONSTAM, R. S., BARREIRO, E. J. AND ALBUQUERQUE, E. X.: Pyrazole, an alcohol dehydrogenase inhibitor, has dual effects on N-methyl-D-aspartate receptors of hippocampal pyramidal cells: Agonist and noncompetitive antagonist. J. Pharmacol. Exp. Ther. 261: 331-340, 1992.
40. ROCHA, E., ALKONDON, M , BURT, D. R. AND ALBUQUERQUE, E. X.: A presynaptic modulatory role for the α-bungarotoxin-sensitive nicotinic acetylcholine receptors (nAChRs) in rat olfactory bulb neurons. Soc. Neurosci. Abs. 21: 1331, 1995.
41. SANDS, S. B. AND BARISH, M E.: Neuronal nicotinic acetylcholine currents in phaeochromocytoma (PC12) cells: Dual mechanisms of rectification. J. Physiol. (Lond.) 447: 467-487, 1992.
42. SCHOEPFER, R., CONROY, W. G., WHITING, P., GORE, M. AND LINDSTROM, J.: Brain alpha-bungarotoxin binding protein cDNAs and MAbs reveal subtypes of this branch of the ligand-gated ion channel gene superfamily. Neuron 5: 35-48, 1990.
43. SEGAL, M.: Imaging of calcium variations in living dendritic spines of cultured rat hippocampal neurons. J. Physiol. (Lond.) 486: 283-295, 1995.
44. SÉGUÉLA, P., WADICHE, J., DINELEY-MILLER, K., DANI, J. A. AND PATRICK, J. W.: Molecular cloning, functional properties and distribution of rat brain α7: A nicotinic cation channel highly permeable to calcium. J. Neurosci. 13: 596-604, 1993.
45. THOMAS, P., BROUGH, P. A., GALLAGHER, T. AND WONNACOTT, S.: Alkyl-modified side chain variants of anatoxin-a: A series of potent nicotinic agonists. Drug Devel. Res. 31: 147-156, 1994.
46. THOMAS, P., STEPHENS, M., WILKIE, G., AMAR, M., LUNT, G. G., WHITING, P., GALLAGHER, T., PEREIRA, E., ALKONDON, M., ALBUQUERQUE, E. X. AND WONNACOTT, S.: (+)-Anatoxin-a is a potent agonist at neuronal nicotinic acetylcholine receptors. J. Neurochem. 60: 2308-2311, 1993.
47. VERNINO, S., AMADOR, M., LUETJE, C. W., PATRICK, J. AND DANI, J. A.: Calcium modulation and high calcium permeability of neuronal nicotinic acetylcholine receptors. Neuron 8: 127-134, 1992.
48. WOODHULL, A. M.: Ionic blockage of sodium channels in nerve. J. Gen. Physiol. 61: 687-708, 1973.
49. ZHANG, Z. W., VIJAYARAGHAVAN, S. AND BERG, D. K.: Neuronal acetylcholine receptors that bind α-bungarotoxin with high affinity function as ligand-gated ion channels. Neuron 12: 167-177, 1994.
50. ZORUMSKI, C. F., THIO, L. L., ISENBERG, K. E. AND CLIFFORD, D. B.: Nicotinic acetylcholine currents in cultured postnatal rat hippocampal neurons. Mol. Pharmacol. 41: 931-936, 1992.