Synthesis and characterisation of 1,3-butadiene DNA-adducts

Fresenius Environmental Bulletin

Volumn 5, Issue 9-10, 1996, Pages 511-516

  Bolt, Hermann M ^a   Jelitto, Brigitte ^a  

^a LEIBNIZ RESEARCH CENTRE FOR WORKING ENVIRONMENT AND HUMAN FACTORS   (Germany)

Author keywords

1,3 butadiene; DNA adducts; genotoxicity

Indexed keywords

EID: 0030423388     PISSN: 10184619     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (4)

1. Jelitto, B., Vangala, R.R. and Laib, R.J. (1989). Species differences in DNA damage by butadiene: role of diepoxybutane. Arch. Toxicol. Suppl. 13: 246-249.
2. Bolt, H.M. and Jelitto, B. (1995). Biological formation of the 1,3-butadiene DNA-adducts 7-N(2-hydroxy-3-buten-1-yl)guanine, 7-N-(1-hydroxy-3-buten-2-yl)guanine and 7-N-(2,3,4-trihydroxybutyl)guanine. Toxicology (in press)
3. Citti, L., Gervasi, P.G., Turchi, G., Belluci, G. and Bianchini, R. (1984). The reaction of 3,4-epoxy-1-butene with deoxyguanosine and DNA in vitro: synthesis and characterization of the main adducts. Carcinogenesis 5: 47-52.
4. van de Ven, F.J.M. and Hilbers, C.W. (1988). Nucleic acids and nuclear magnetic resonance. Eur. J. Biochem. 178, 1-38.