High-dose adrenaline with low systemic vascular resistance and symmetrical peripheral gangrene

South African Journal of Surgery

Volumn 34, Issue 2, 1996, Pages 99-101

  Joynt, G ^a   Doedens, L ^a   Lipman, J ^a   Bothma, P ^a  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; LACTIC ACID;

ADULT; ARTICLE; CASE REPORT; GANGRENE; HUMAN; LACTATE BLOOD LEVEL; MALE; PULSE RATE; SYNDROME; SYSTEMIC VASCULAR RESISTANCE;

ADULT; CARDIAC OUTPUT; EPINEPHRINE; GANGRENE; HUMANS; HYPOTENSION; LACTIC ACID; MALARIA, FALCIPARUM; MALE; SYNDROME; VASCULAR RESISTANCE; VASOCONSTRICTOR AGENTS;

EID: 0030420567     PISSN: 00382361     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Hayes MA, Yan EHS, Hinds CJ, Watson JD. Symmetrical peripheral gangrene association with noradrenaline administration. Crit Care Med 1992; 18: 433-436.
2. Molos MA, Hall JC. Symmetrical peripheral gangrene and disseminated intravascular coagulation. Arch Dermatol 1985; 121: 1057-1061.
3. Johansen K, Murphy T, Pavlin E, Ledbetter D. Digital ischaemia complicating pneumococcal sepsis: reversal with sympathetic blockade. Crit Care Med 1991; 19: 114-116.
4. Alexander C, Sako Y, Mikulic E. Pedal gangrene associated with the use of dopamine. N Engl J Med 1975; 293: 591.
5. Winkler MJ, Trunkey DD. Dopamine gangrene: association with disseminated intravascular coagulation. Am J Surg 1981; 142: 588-591.
6. Greene SI, Smith JW. Dopamine gangrene. N Engl J Med 1976; 274: 114.
7. Barriere SL. Gangrene and dopamine. Ann Intern Med 1977; 86: 366-367.
8. Mackenzie SJ, Kappadia F, Nimmo GR, Armstrong IR, Grant IS. Adrenaline in treatment of septic shock: effects on haemodynamics and oxygen transport. Intensive Care Med 1991; 17: 36-39.
9. Lipman J, Roux R, Kraus P. Vasoconstrictor effect of adrenaline in human septic shock. Anaesth Intens Care 1991; 19: 61-65.
10. Wilson W, Lipman J, Scribante J, et al. Septic shock: does adrenaline have a role as a first line inotropic agent? Anaesth Intens Care 1992; 20: 470-474.
11. Hindman BJ. Sodium bicarbonate in the treatment of subtypes of acute lactic acidosis: physiologic considerations. Anesthesiology 1990; 72: 1064-1076.
12. Weil MH, Afifi AA. Experimental and clinical studies on lactate and pyruvate as indicators of the severity of acute circulatory• failure (shock). Circulation 1970; 61: 989-1001.
13. Mizock BA, Falk JL. Lactic acidosis in critical illness. Crit Care Med 1992; 20: 80-93.
14. Denning DW, Gilliland L, Hewlett A, Hughes LO, Reid CDL. Peripheral symmetrical gangrene successfully treated with epoprostenol and tissue plasminogen activator. Lancet 1986; 2: 1401-1402.