Low urinary GH levels in normal statured obese children

Acta Paediatrica, International Journal of Paediatrics

Volumn 85, Issue 8, 1996, Pages 894-898

  Sartorio, A ^a,b   Conti, A ^a   Ferrero, S ^a  

^a ISTITUTO AUXOLOGICO ITALIANO   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

Body mass index; Obesity; Urinary GH

Indexed keywords

GROWTH HORMONE;

ADOLESCENT; AGE; ARTICLE; BODY MASS; CHILD; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NORMAL VALUE; OBESITY; PRIORITY JOURNAL; PUBERTY; URINE LEVEL;

EID: 0030407241     PISSN: 08035253     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1651-2227.1996.tb14178.x     Document Type: Article

References (25)

1. Bell JP, Donald RA, Espiner EA. Pituitary response to insulin-induced hypoglycemia in obese subjects before and after fasting. J Clin Endocrinol Metab 1970;31:546-51
2. Van Vliet G, Bosson D, Rummens E, Robyn C, Wolter R. Evidence against growth hormone-releasing factor deficiency in children with idiopathic obesity. Acta Endocrinol 1986;279 suppl:403-10
3. Loche S, Cappa M, Borrelli P, Faedda A, Crino A, Cella SG, et al. Reduced growth hormone response to growth hormone-releasing hormone in children with simple obesity: evidence for somatomedin-C mediated inhibition. Clin Endocrinol 1987;27:145-53
4. Glass AR. Endocrine aspects of obesity. Med Clin North Am 1989;73:139-60
5. Sartorio A, Bochicchio D, Morabito F, Faglia G. Growth hormone responsiveness to GHRH in obese children before and after weight loss. Acta Paediatr Scand 1989;78:329-30
6. Tanaka K, Inoue S, Numata K, Okazaki H, Nakamura S, Takamura Y. Very low calorie diet-induced weight reduction reverses impaired growth hormone secretion response to growth hormone-releasing hormone, arginine and L-dopa in obesity. Metabolism 1990;39:892-6
7. Kelijman M, Frohman LA. Responsiveness to GH-releasing hormone after dietary manipulation in obese and non-obese subjects. J Clin Endocrinol Metab 1988;66:489-94
8. Bercu BB, Shulman DI, Root AW. Obesity decreases endogenous growth hormone secretion in children with normal growth velocities. Pediatr Res 1988;23:272-7
9. Veldhuis JD, Iranmanesh A, Ho KKY, Waters MJ, Johnson ML, Lizarralde G. Dual defects in pulsatile growth hormone secretion and clearance subserve the hyposomatropism of obesity in man. J Clin Endocrinol Metab 1991;72:51-9
10. Rasmussen MH, Hvidberg A, Juul A, Main KM, Gotfredsen A, Skakkebaek NE, et al. Massive weight loss restores 24-hour growth hormone release profiles and serum insulin-like growth factor-1 levels in obese subjects. J Clin Endocrinol Metab 1995;80:1407-15
11. Quabbe HJ, Helge H, Kubicki S. Nocturnal growth hormone secretion: correlation with sleeping EEG in adults and pattern in children and adolescents with non-pituitary dwarfism, overgrowth and with obesity. Acta Endocrinol 1971;67:767-83
12. Tomita H, Ogawa M, Kamijo T, Mori O, Ishikawa E, Mohri Z, et al. Highly sensitive sandwich enzyme immunoassay of urinary growth hormone in children with short stature, Turner's syndrome, and simple obesity. Acta Endocrinol 1989;121:513-9
13. Patel L, Skinner AM, Price DA, Clayton PE. The influence of body mass index on growth hormone secretion in normal and short statured children. Growth Regul 1994;4:29-34
14. Rolland-Cachera MF, Sempè M, Guilloud-Bataille M, Patois E, Pequignot-Guggenbuhl F, Fautrad V. Adiposity indices in children. Am J Clin Nutr 1982;36:178-84
15. Hammer LD, Kraemer HC, Wilson D, Ritter PL, Dornbusch SM. Standardized percentile curves of body-mass index for children and adolescents. Am J Dis Child 1991;145:259-63
16. Girard J, Erb T, Pampalone A, Eberle AN, Baumann JB. Growth hormone in urine: development of an ultrasensitive assay applicable to plasma and urine. Horm Res 1987;28:71-80
17. Sukegawa I, Hizuka N, Takano K, Asakawa K, Horikawa R, Hahida S, et al. Urinary growth hormone (GH) measurements are useful for evaluating endogenous GH secretion. J Clin Endocrinol Metab 1988;66:1119-23
18. Sukegawa I, Hizuka N, Takano K, Asakawa K, Horikawa R, Hahida S, et al. Measurement of nocturnal urinary growth hormone values. Acta Endocrinol 1989;121:290-6
19. Girard J, Celniker A, Price A, Tanaka T, Walker J, Welling K, et al. Urinary measurement of growth hormone secretion. Acta Paediatr Scand 1990;366 suppl:149-54
20. Kohno H, Murakami Y, Kodaira T. Urinary human growth hormone measurement using a highly sensitive sandwich enzyme immunoassay: diagnostic and therapeutic uses in patients with growth hormone deficiency. J Clin Endocrinol Metab 1990;71: 1496-500
21. Walker JM, Wood PJ, Williamson S, Betts PR, Evans AJ. Urinary growth hormone excretion as a screening test for growth hormone deficiency. Arch Dis Child 1990;65:89-92
22. Main KM, Jarden M, Angelo L, Dinesen B, Hertel NT, Juul A, et al. The impact of gender and puberty on reference values for urinary growth hormone excretion: a study of three morning urine samples in 517 healthy children and adults. J Clin Endocrinol Metab 1994;79:865-71
23. Léger J, Reverchon C, Porquet D, Noel M, Czernichow P. The wide variation in urinary excretion of human growth hormone in normal growing and growth hormone-deficient children limits its clinical usefulness. Horm Res 1995;44:57-63
24. Hattori N, Shimutsu A, Kato Y, Koshiyama H, Ishikawa Y, Tanoh T, et al. Urinary excretion of human growth hormone: daily variation and relationship with albumin and alpha 1-micro-globulin in urine. Acta Endocrinol 1989;121:533-7
25. Main K, Philips M, Jorgensen M, Skakkebaek NE. Urinary growth hormone excretion in 657 healthy children and adults: normal values, inter- and intra-individual variations. Horm Res 1991;36:174-82