Transcription targets recombination at immunoglobulin switch sequences in a strand-specific manner

Current Topics in Microbiology and Immunology

Volumn 217, Issue , 1996, Pages 171-189

  Daniels, Gregory A ^a   Lieber, Michael R ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; B LYMPHOCYTE DIFFERENTIATION; CHROMATIN STRUCTURE; DNA SEQUENCE; EFFECTOR CELL; GENE LOCUS; GENE SWITCHING; GENE TARGETING; GENETIC RECOMBINATION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ASSEMBLY; TRANSCRIPTION REGULATION;

ANIMALIA;

EID: 0030404469     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-50140-1_12     Document Type: Article

References (39)

1. Burrows PD, Beck-Engeser GB, Wabl MR (1983) Immunoglobulin heavy-chain class switching in a pre-B cell line is accompanied by DNA rearrangement Nature 306 243-246
2. Clark DJ, Felsenfeld G (1992) A nucleosome core is transferred out of the path of a transcribing polymerase. Cell 71 11-22
3. Coffman RL, Lebman DA, Rothman P (1993) Mechanism and regulation of immunoglobulin isotype switching Adv Immunol 54 229-270
4. Daniels GA, Lieber MR (1995) Strand-specificity in the transcriptional targeting of recombination at immunoglobulin class switch sequences Proc Natl Acad Sci USA 92 5625-5629
5. Davis M, Kim SK, Hood LE (1980) DNA sequences mediating class switching in a-immunoglobulins Science 209.1360-1365
6. Davis MM, Kim SK, Hood L (1980) Immunoglobulin class switching developmentally regulated DNA rearrangements during differentiation Cell 22 1-2
7. DePinho R, Kruger K, Andrews N, Lutzker S, Baltimore D, Alt FW (1984) Molecular basis of heavy-chain class switching and switch region deletion in an Abelson virus-transformed cell line Mol Cell Biol 4.2905-2910
8. Dunnick WA, Hertz GZ, Scappino L, Gritzmacher C (1993) DNA sequence at immunoglobulin switch region recombination sites Nucl Acid Res 21.365-372
9. Gerstein RM, Frankel WN, Hsieh C-L, Durdik JM, Rath S, Coffin JM, Nisonoff A, Selsing E (1990) Isotype switching of an immunoglobulin heavy chain transgene occurs by DNA recombination between different chromosomes Cell 63:537-548
10. Gritzmacher CA (1989) Molecular aspects of heavy-chain class switching. Crit Rev Immunol 9:173-200
11. Gu H, Zou Y-R, Rajewsky K (1993) Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting. Cell 73:1155-1164
12. Hesse JE, Lieber ML, Gellert M, Mizuuchi K (1987) Extrachromosomal substrates undergo inversion or deletion at immunoglobulin VDJ joining signals. Cell 49 775-783
13. Jack HM, McDowell M, Steinberg CM, Wabl M (1988) Looping Out and deletion mechanism for the immunoglobulin heavy-chain class switch Proc Natl Acad Sci 85 1581-1585
14. Jung S, Rajewsky K, Radbruch A (1993) Shutdown of class switch recombination by deletion of a switch region control element Science 259:984-987
15. Lepse CL, Kumar R, Ganea D (1994) Extrachromosomal eukaryotic DNA substrates for switch recombination: analysis of isotype and cell specificity DNA. Cell Biol 13 1151-61
16. Leung H, Maizels N (1992) Transcriptional regulatory elements stimulate recombination in extrachromosomal substrates carrying immunoglobulin switch-region sequences. Proc Natl Acad Sci 89:4154-4158
17. Leung H, Maizels N (1994) Regulation and targeting of recombination in extrachromosomal substrates carrying immunoglobulin switch region sequences Mol Cell Biol 14 1450-1458
18. Liao P, Giannmi SL, Birshtein BK (1992) A nuclear DNA-binding protein expressed during early stages of B cell differentiation interacts with diverse segments within and 3′ of the Ig H chain gene cluster J Immunol 148.2909-2917
19. Lieber ML, Hesse JE, Mizuuchi K, Gellert M (1987) Developmental stage specificity of the lymphoid V(D)J recombination activity Genes Dev 1:751-761
20. Lutzker SG, Alt FW (1989) Immunoglobulin heavy-chain class switching in. Berg DE, Howe MM (eds) Mobile DNA American Society for Microbiology, Washington, DC, pp 693-714
21. Marcu KB, Banerji J, Penncavage NA, Lang R, Arnheim N (1980) 5′ flanking region of immunoglobulin heavy chain constant region genes display length heterogeneity in germlines of inbred mouse strains Cell 22 187-196
22. Ott DE, Alt FW, Marcu KB (1987) Immunoglobulin heavy chain switch region recombination within a retroviral vector in murine pre-B cells. EMBO 6 577-584
23. Petrini J, Dunnick W (1989) Products and implied mechanism of H chain switch recombination J Immunol 142 2932-2935
24. Reaban ME, Griffin JA (1990) Induction of RNA-stabilized DNA conformers by transcription of an immunoglobulin switch region. Nature 348:342-344
25. Schwedler UV, Jack H-M, Wabl M (1990) Circular DNA is a product of the immunoglobulin class switch rearrangement. Nature 345.452-456
26. Stavnezer J, Abbott J, Sirlin S (1984) Immunoglobulin heavy chain switching in culture 129 murine B lymphoma cells.commitment to an IgA or IgE switch Curr Topics Microbiol Immunol 113 109-115
27. Stavnezer J, Radcliff G, Lin Y-C, Nietupski J, Berggren L, Sitia R, Severinson E (1988) Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes Proc Natl Acad Sci USA 85:7704-7708
28. Stavnezer-Nordgren J, Sirlin S (1986) Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching EMBO 5 95-102
29. Sugiyama H, Maeda T, Akira S, Kishimoto S (1986) Class-switching from μ to γ3 or γ2b production at pre-B cell stage. J Immunol 136.3092-3097
30. Szurek P, Petrini J, Dunnick W (1985) Complete nucleotide sequence of the murine γ3 switch region and analysis of switch recombination sites in two γ3-expressing hybridomas J Immunol 135 620-626
31. Waters SH, Saikh KU, Stavnezer J (1989) A B-cell-specific nuclear protein that binds to DNA sites 5′ to immunoglobulin Sα tandem repeats is regulated during differentiation Mol Cell Biol 9:5594-5601
32. White MB, Word CJ, Humphries CG, Blattner FR, Tucker PW (1990) Immunoglobulin D switching can occur through homologous recombination in human B cells Mol Cell Biol 10:3690-3699
33. Williams M, Maizels N (1991) LR1, a lipopolysacharide-responsive factor with binding sites in the immunoglobulin switch regions and heavy-chain enhancer. Genes Dev 5 2353-2361
34. Wuerffel R, Jamieson CE, Morgan L, Merkulov GV Sen R, Kenter AL (1992) Switch recombination breakpoints are strictly correlated with DNA recognition motifs for immunoglobulin Sγ3 DNA-binding proteins J Exp Med 176 339-349
35. Xu L, Gorham B, Li SC, Bottaro A, Alt FA, Rothman P (1993) Replacement of germ-line e promoter by gene targeting alters control of immunoglobulin heavy chain class switching. Proc Natl Acad Sci 90:3705-3709
36. Xu M, Stavnezer J (1992) Regulation of transcription of immunoglobulin germ-line g1 RNA: analysis of the promoter/enhancer. EMBO 11:145-155
37. Yancopoulos GD, DePinho RA, Zimmerman KA, Lutzker SG, Rosenberg N, Alt FW (1986) Secondary genomic rearrangement events in pre-B cells: VhDJh replacement by a LINE-1 sequence and directed class switching. EMBO 5:3259-3266
38. Yasui H, Akahori Y, Hirano M, Yamada K, Kurosawa Y (1989) Class switch from μ to δ is mediated by homologous recombination between σμ and Σμ sequences in human immunoglobulin gene loci. Eur J Immunol 19:1399-1403
39. Zhang J, Bottaro A, Li S, Stewart V Alt F (1993) A selective defect in IgG2b switching as a result of targeted mutation of the Iγ2b promoter and exon. EMBO J 12:3529-3537