Cell growth inhibition by antitumor prostaglandin and its modulation by MRP/GS-X pump

Advances in Experimental Medicine and Biology

Volumn 407, Issue , 1996, Pages 387-391

  Akimaru, Kunihiro ^a   Nakanishi, Makoto ^b   Suzuki, Masaaki ^c   Furuta, Kyoji ^c   Noyori, Ryoji ^d   Ishikawa, Toshihisa ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b JICHI MEDICAL UNIVERSITY   (Japan)

^c GIFU UNIVERSITY   (Japan)

^d NAGOYA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

15 HYDROXY 9 OXOPROSTA 7,10,13 TRIENOIC ACID METHYL ESTER; ANTINEOPLASTIC AGENT; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLINE; GLUTATHIONE TRANSFERASE; PROSTAGLANDIN; PROSTAGLANDIN A2; PROTEIN P21; PROTEIN P53; RETINOBLASTOMA PROTEIN; RNA; UNCLASSIFIED DRUG;

ANION TRANSPORT; ANTINEOPLASTIC ACTIVITY; CANCER CELL; CANCER INHIBITION; CELL PROLIFERATION; CELL STRAIN HL 60; CONFERENCE PAPER; CONTROLLED STUDY; HUMAN; HUMAN CELL; NORTHERN BLOTTING; ONCOGENE C MYC; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; CELL CYCLE; CISPLATIN; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASES; CYCLINS; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, LEUKEMIC; GENES, MYC; GROWTH INHIBITORS; HL-60 CELLS; HUMANS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; PROSTAGLANDINS A, SYNTHETIC;

EID: 0030391584     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper

References (20)

1. S. Narumiya and M. Fukushima, Cyclopentenone prostaglandins: anti-proliferative and anti-viral actions and their molecular mechanism, in: Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury, K.V. Honn, L.J. Marnett, S. Nigam, T. Walden, eds., Kluwer Academic Publisher, Boston (1989).
2. S. Narumiya and M. Fukushima, Site and mechanism of growth inhibition by prostaglandins. I. active transport and intracellular accumulation of cyclopentenone prostaglandins, a reaction leading to growth inhibition, J. Pharmacol. Exp. Ther. 239: 500 (1986).
3. S. Narumiya, K. Ohno, M. Fujiwara, and M. Fukushima, Site and mechanism of growth inhibition by prostaglandins. II. temperature-dependent transfer of a cyclopentenone prostaglandin to nuclei, J. Pharmacol. Exp. Ther. 239: 506 (1986).
4. 1-enriched HeLa S3 cells, J. Pharmacol. Exp. Ther. 245:294 (1988).
5. R. Noyori and M. Suzuki, Organic synthesis of prostaglandins: advancing biology, Science 259: 44 (1993).
6. R. Noyori, H. Koyano, M. Mori, R. Hirata, Y. Shiga, T. Kokura, and M. Suzuki, Unnatural prostaglandins of biochemical and physiological significance, Pure Appl. Chem. 66: 1999 (1994).
7. S.J. Elledge and J.W. Harper, Cdk inhibitors: on the threshold of checkpoints and development, Curr. Opin. Cell. Biol. 6 847 (1994).
8. T. Ishikawa, C.D. Wright, and H. Ishizuka, GS-X pump is functionally overexpressed in cis-diamminedichloroplatinum(II)-resistant leukemia HL-60 cells and down-regulated by cell differentiation, J. Biol Chem. 269: 29085 (1994).
9. J. Sambrook, E.F. Fritsch, and T. Maniatitis, Molecular Cloning; A Laboratory Manual, 2nd edition. Cold Spring Harbor Laboratory Press, Cold Spring Harbor (1990).
10. 1 cyclin-dependent kinases, Cell 75, 805 (1993).
11. Y. Xiong, G.J. Hannon, H. Zhang, D. Casso, R. Kobayashi, and D. Beach, p21 is a universal inhibitor of cyclin kinases, Nature, 366, 701 (1993).
12. 1 arrest and apoptosis, Cancer Res. 54, 1169 (1994).
13. 1 arrest, Cell 76, 1013 (1994).
14. A. Noda, Y. Ning, S.F. Venable, O.M. Pereira-Smith, and J.R. Smith, Cloning of senescenct cell-derived inhibitors of DNA synthesis using an expression screen, Exp. Cell Res. 211, 90 (1994).
15. sdi1 antisense RNA, Proc. Natl. Acad. Sci. USA 92, 4352 (1995).
16. T. Ishikawa, The ATP-dependent glutathione S-conjugate export pump, Trends Biochem. Sci. 17: 463 (1992).
17. T. Ishikawa and F. Ali-Osman, Glutathione-associated cis-diamminedichloroplatinum(II) metabolism and ATP-dependent efflux from leukemia cells, J. Biol. Chem. 268: 20116 (1993).
18. M. Müller, C. Meijer, G.J.R. Zaman, P. Borst, R.J. Scheper, N.H. Mulder, E.G.E, de Vries, and P.L.M. Jansen, Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport, Proc. Natl Acad. Sci. 91:13033 (1994).
19. 4 and structurally related conjugates, J. Biol. Chem. 269: 27807 (1994).
20. K. Akimaru, M.T. Kuo, M. Suzuki, K. Furuta, R. Noyori, and T. Ishikawa, Induction of MRP/GS-X pump and cellular resistance to anticancer prostaglandins, Cytotech. in press (1995).