Age-dependent variation in the serum concentration of mannan-binding protein

Acta Paediatrica, International Journal of Paediatrics

Volumn 85, Issue 8, 1996, Pages 906-909

  Aittoniemi, J ^a   Miettinen, A ^a   Laippala, P ^b   Isolauri, E ^b   Viikari, J ^c   Ruuska, T ^a   Soppi, E ^a  

^a TAMPERE UNIVERSITY HOSPITAL   (Finland)

^b TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^c UNIVERSITY OF TURKU   (Finland)

Author keywords

Immunodeficiency; Mannan binding protein; Mannose binding protein; Opsonization

Indexed keywords

ACUTE PHASE PROTEIN; MANNAN; MANNOSE BINDING PROTEIN;

AGE; ARTICLE; BLOOD LEVEL; CHILD; CHILDHOOD DISEASE; ENZYME IMMUNOASSAY; FINLAND; HUMAN; IMMUNE RESPONSE; INFANT; INFECTION; NEWBORN; NORMAL HUMAN; OPSONIZATION; PRESCHOOL CHILD; PRIORITY JOURNAL;

EID: 0030391388     PISSN: 08035253     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1651-2227.1996.tb14182.x     Document Type: Article

References (24)

1. Soothill JF, Harvey BAM. Defective opsonization. A common immunity deficiency. Arch Dis Child 1976;51:91-9
2. Levinsky RJ, Harvey BAM, Paleja S. A rapid objective method for measuring the yeast opsonisation activity of serum. J Immunol Methods 1978;24:251-6
3. Kerr MA, Falconer JS, Bashey A, Swanson Beck J. The effect of C3 levels on yeast opsonization by normal and pathological sera: identification of a complement independent opsonin. Clin Exp Immunol 1983;54:793-800
4. Turner MW, Grant C, Seymour ND, Harvey B, Levinsky RJ. Evaluation of C3b/C3bi opsonization and chemiluminescence with selected yeasts and bacteria using sera of different opsonic potential. Immunology 1986;58:111-5
5. Candy DCA, Larcher VF, Tripp JH, Harries JT, Harvey BAM, Soothill JF. Yeast opsonization in children with chronic diarrhoeal states. Arch Dis Child 1980;55:189-93
6. Richardson VF, Larcher VF, Price JF. A common congenital immunodeficiency predisposing to infection and atopy in infancy. Arch Dis Child 1983;58:799-802
7. Turner MW, Mowbray JF, Roberton DR. A study of C3b deposition on yeast surfaces by sera of known opsonic potential. Clin Exp Immunol 1981;46:412-9
8. Turner MW, Seymour ND, Kazatchkine MD, Mowbray JF. Suboptimal C3b/C3bi deposition and defective yeast opsonization. I. Evidence for the absence of essential co-factor activity. Clin Exp Immunol 1985;62:427-34
9. Super M, Levinsky RJ, Turner MW. The level of mannan-binding protein regulates the binding of complement-derived opsonins to mannan and zymosan at low serum concentrations. Clin Exp Immunol 1990;79:144-50
10. Super M,Thiel S, Lu J, Levinsky RJ, Turner MW. Association of low levels of mannan-binding protein with a common defect of opsonisation. Lancet 1989;ii:1236-9
11. Sumiya M, Super M, Tabona P, Levinsky RJ, Arai T, Turner MW. et al. Molecular basis of opsonic defect in immunodeficient children. Lancet 1991;337:1569-70
12. Lipscombe RJ, Sumiya M, Hill AVS, Lau YL, Levinsky RJ, Summerfield JA, et al. High frequencies in African and non-African populations of independent mutations in the mannose binding protein gene. Hum Mol Gen 1992;1:709-15
13. Madsen HO, Garred P, Kurtzhals JAL, Lamm LU, Ryder LP, Thiel S, et al. A new frequent allele is the missing link in the structural polymorphism of the human mannan-binding protein. Immunogenetics 1994;40:37-44
14. Garred P, Thiel S, Madsen HO, Ryder LP, Jensenius JC, Svejgaard A. Gene frequency and partial protein characterization of an allelic variant of mannan binding protein associated with low serum concentrations. Clin Exp Immunol 1992;90:517-21
15. Garred P, Madsen HO, Kurtzhals JAL, Lamm LU, Thiel S, Hey AS, et al. Diallelic polymorphism may explain variations of the blood concentration of mannan-binding protein in Eskimos, but not in black Africans. Eur J Immunogenetics 1992;19:403-12
16. Terai I, Kobayashi K, Fujita T, Hagiwara K. Human serum mannose binding protein (MBP): development of an enzyme-linked immunosorbent assay (ELISA) and determination of levels in serum from 1085 normal Japanese and in some body fluids. Biochem Med Metab Biol 1993;50:111-9
17. Lipscombe RJ, Lau YL, Levinsky RJ, Sumiya M, Summerfield JA, Turner MW. Identical point mutation leading to low levels of mannose binding protein and poor C3b mediated opsonisation in Chinese and Caucasian populations. Immunol Lett 1992;32:253-8
18. Thiel S, Holmskov U, Hviid L, Laursen SB, Jensenius JC. The concentration of the C-type lectin. mannan- binding protein, in human plasma increases during an acute phase response. Clin Exp Immunol 1992;90:31-5
19. Ruuska T, Vesikari T, Delem A, André FE, Beards GM, Flewett TH. Evaluation of RIT 4237 bovine rotavirus vaccine in newborn infants: correlation of vaccine efficacy to season of birth in relation to rotavirus epidemic period. Scand J Infect Dis 1990;22:269-78
20. Åkerblom HK, Viikari J, Uhari M, Räsänen L, Byckling T, Louhivuori K, et al. Atherosclerosis precursors in Finnish children and adolenscents. I. General description of the cross-sectional study of 1980, and an account of the children's and families' state of health. Acta Paediatr Scand 1985;Suppl 318:49-63
21. Terai I, Kobayashi K. Perinatal changes in serum mannose-binding protein (MBP) levels. Immunol Lett 1993;38(3):185-7
22. Thiel S, Bjerke T, Hansen D, Poulsen LK, Schiotz PO, Jensenius JC. Ontogeny of human mannan-binding protein, a lectin of the innate immune system. Pediatr Allergy Immunol 1995;6:20-3
23. Summerfield JA, Ryder S, Sumiya M, Thursz M, Gorchein A, Monteil MA, et al. Mannose binding protein gene mutations associated with unusual and severe infections in adults. Lancet 1995;345:886-9
24. Turner MW, Super M, Singh S, Levinsky RJ. Molecular basis of a common opsonic defect. Clin Exp Allergy 1991;21Suppl 1:182-8