Six-month oral toxicity study of tolcapone in rat (feed admix)

Japanese Pharmacology and Therapeutics

Volumn 24, Issue SUPPL. 10, 1996, Pages 49-75

  Schläppi, Bernhard ^a   Jovanovic, Desa ^a   Okada, Masako ^a   Kobayashi, Kazuko ^a   Horii, Ikuo ^a  

^a Preclinical Research   (Switzerland)

Author keywords

COMT inhibitor; Rat; Six month toxicity; Tolcapone

Indexed keywords

BILIRUBIN; CATECHOL METHYLTRANSFERASE INHIBITOR; TOLCAPONE;

ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DOSE RESPONSE; DRUG FORMULATION; DRUG TOLERABILITY; ERYTHROCYTE; FEMALE; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; TOXICITY TESTING; URINE COLOR;

EID: 0030390347     PISSN: 03863603     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Saner A et al : Research Report B-157680 : November 15, 1991
2. Lüdin E : Arch Toxicol 58 : 57-58, 1985
3. Rao CR : Biometrics 14 : 133-145, 1958
4. Trieb G et al : Toxicol Appl Pharmacol 35 : 531-542, 1976
5. Everds N : Research Report N-138370 : Feb, 1995