메뉴 건너뛰기




Volumn 44, Issue , 1996, Pages 175-187

Pathophysiological features of hereditary cancers

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL MODEL; CANCER GENETICS; CANCER SUSCEPTIBILITY; CARCINOGENESIS; DOMINANT INHERITANCE; FAMILIAL CANCER; GENE MAPPING; GENE STRUCTURE; HETEROZYGOTE; HUMAN; KIDNEY CARCINOMA; MUTATION; NONHUMAN; PEDIGREE; PRIORITY JOURNAL; RAT; REVIEW; TUBEROUS SCLEROSIS;

EID: 0030378273     PISSN: 00720151     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Review
Times cited : (4)

References (28)
  • 2
    • 0001011456 scopus 로고
    • A dominant gene for renal adenomas in the rats
    • Eker, R. and Mossige, J. A dominant gene for renal adenomas in the rats. Nature, 189, 858-859 (1961).
    • (1961) Nature , vol.189 , pp. 858-859
    • Eker, R.1    Mossige, J.2
  • 3
    • 0026470327 scopus 로고
    • Hereditary renal cell carcinoma in the Eker rat: A rodent familial cancer syndrome
    • Everitt, J. I., Goldsworthy, T. L., Wolf, D. S., and Walker, C. L. Hereditary renal cell carcinoma in the Eker rat: a rodent familial cancer syndrome. J. Urol., 148, 1932-1936 (1992).
    • (1992) J. Urol. , vol.148 , pp. 1932-1936
    • Everitt, J.I.1    Goldsworthy, T.L.2    Wolf, D.S.3    Walker, C.L.4
  • 4
    • 0027954044 scopus 로고
    • Mutations of the VHL tumor suppressor gene in renal carcinoma
    • Gnarra, J. R. Mutations of the VHL tumor suppressor gene in renal carcinoma. Nat. Genet., 7, 85-90 (1994).
    • (1994) Nat. Genet. , vol.7 , pp. 85-90
    • Gnarra, J.R.1
  • 5
    • 0028289473 scopus 로고
    • Loss of heterozygosity on chromosome 16p13.3 in hamartomas from tuberous sclerosis patients
    • Green, A. J., Smith, M., and Yates, J.R.W. Loss of heterozygosity on chromosome 16p13.3 in hamartomas from tuberous sclerosis patients Nat. Genet., 6, 193-196 (1994).
    • (1994) Nat. Genet. , vol.6 , pp. 193-196
    • Green, A.J.1    Smith, M.2    Yates, J.R.W.3
  • 6
    • 0027458433 scopus 로고
    • Spontaneous and radiation-induced renal tumors in the Eker rat model of dominantly inherited cancer
    • Hino, O., Klein-Szanto, A.J.P., Freed, J. J., et al. Spontaneous and radiation-induced renal tumors in the Eker rat model of dominantly inherited cancer. Proc. Natl. Acad. Sci. USA., 90, 327-331 (1993).
    • (1993) Proc. Natl. Acad. Sci. USA. , vol.90 , pp. 327-331
    • Hino, O.1    Klein-Szanto, A.J.P.2    Freed, J.J.3
  • 8
    • 0027139911 scopus 로고
    • Genetic predisposition to transplacentally induced renal cell carcinomas in the Eker rat
    • Hino, O., Mitani, H., and Knudson, A. G. Genetic predisposition to transplacentally induced renal cell carcinomas in the Eker rat. Cancer Res., 53, 5856-5858 (1993).
    • (1993) Cancer Res. , vol.53 , pp. 5856-5858
    • Hino, O.1    Mitani, H.2    Knudson, A.G.3
  • 9
    • 0028021756 scopus 로고
    • A novel cancer/predisposition syndrome in the Eker rat model
    • Hino, O., Mitani, H., Katsuyama, H. and Kubo, Y. A novel cancer/predisposition syndrome in the Eker rat model. Cancer Lett., 83, 117-121 (1994).
    • (1994) Cancer Lett. , vol.83 , pp. 117-121
    • Hino, O.1    Mitani, H.2    Katsuyama, H.3    Kubo, Y.4
  • 10
    • 0028065161 scopus 로고
    • The predisposing gene of the Eker rat inherited cancer syndrome is tightly linked to the tuberous sclerosis (TSC2) gene
    • Hino, O., Kobayashi, T., Tsuchiya, H. et al. The predisposing gene of the Eker rat inherited cancer syndrome is tightly linked to the tuberous sclerosis (TSC2) gene. Biochem. Biophys. Res. Commun., 203, 1302-1308 (1994).
    • (1994) Biochem. Biophys. Res. Commun. , vol.203 , pp. 1302-1308
    • Hino, O.1    Kobayashi, T.2    Tsuchiya, H.3
  • 11
    • 0028935095 scopus 로고
    • The Eker rat, a model of dominantly inherited cancer syndrome
    • Hino, O., Kobayashi, T., Mitani, H., Kubo, H. et al. The Eker rat, a model of dominantly inherited cancer syndrome. Transplant. Proc., 27, 1529-1531 (1995).
    • (1995) Transplant. Proc. , vol.27 , pp. 1529-1531
    • Hino, O.1    Kobayashi, T.2    Mitani, H.3    Kubo, H.4
  • 12
    • 0028822319 scopus 로고
    • Molecular genetic basis of renal carcinogenesis in the Eker rat model of tuberous sclerosis (Tsc2)
    • Hino, O., Kobayashi, E., Hirayama, Y. et al. Molecular genetic basis of renal carcinogenesis in the Eker rat model of tuberous sclerosis (Tsc2). Mol. Carcinog., 14, 23-27 (1995).
    • (1995) Mol. Carcinog. , vol.14 , pp. 23-27
    • Hino, O.1    Kobayashi, E.2    Hirayama, Y.3
  • 14
    • 0028815637 scopus 로고
    • Cloning of the rat homologue of the von Hippel-Lindau tumor suppressor gene and its non-somatic mutation in rat renal cell carcinomas
    • Kikuchi, Y., Kobayashi, E., Nishizawa, M., Hamazaki, S., Okada, S., and Hino, O. Cloning of the rat homologue of the von Hippel-Lindau tumor suppressor gene and its non-somatic mutation in rat renal cell carcinomas. Jpn. J. Cancer Res., 86, 905-909 (1995).
    • (1995) Jpn. J. Cancer Res. , vol.86 , pp. 905-909
    • Kikuchi, Y.1    Kobayashi, E.2    Nishizawa, M.3    Hamazaki, S.4    Okada, S.5    Hino, O.6
  • 15
    • 0021879645 scopus 로고
    • Hereditary cancer, oncogenes, and antioncogenes
    • Knudson, A. G. Hereditary cancer, oncogenes, and antioncogenes. Cancer Res., 45, 1437-1443 (1985).
    • (1985) Cancer Res. , vol.45 , pp. 1437-1443
    • Knudson, A.G.1
  • 16
    • 0028830856 scopus 로고
    • A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancer
    • Kobayashi, T., Hirayama, Y., Kobayashi, E., Kubo, Y., and Hino, O. A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancer. Nat. Genet., 9, 70-74 (1995).
    • (1995) Nat. Genet. , vol.9 , pp. 70-74
    • Kobayashi, T.1    Hirayama, Y.2    Kobayashi, E.3    Kubo, Y.4    Hino, O.5
  • 17
    • 0029095041 scopus 로고
    • cDNA structure, alternative splicing and exon-intron organization of the predisposing tuberous sclerosis (Tsc2) gene of the Eker rat model
    • Kobayashi, T., Nishizawa, M., Hirayama, Y., Kobayashi, E., and Hino, O. cDNA structure, alternative splicing and exon-intron organization of the predisposing tuberous sclerosis (Tsc2) gene of the Eker rat model. Nucl. Acids Res., 23, 2608-2613 (1995).
    • (1995) Nucl. Acids Res. , vol.23 , pp. 2608-2613
    • Kobayashi, T.1    Nishizawa, M.2    Hirayama, Y.3    Kobayashi, E.4    Hino, O.5
  • 18
    • 0028228998 scopus 로고
    • Allelic loss at the predisposing gene locus in spontaneous and chemically induced renal cell carcinomas in the Eker rat
    • Kubo, Y., Mitani, H., and Hino, O. Allelic loss at the predisposing gene locus in spontaneous and chemically induced renal cell carcinomas in the Eker rat. Cancer Res., 54, 2633-2635 (1994).
    • (1994) Cancer Res. , vol.54 , pp. 2633-2635
    • Kubo, Y.1    Mitani, H.2    Hino, O.3
  • 19
    • 0028913673 scopus 로고
    • Early detection of Knudson's two-hits in preneoplastic renal cells of the Eker rat model by the laser microdissection procedure
    • Kubo, Y., Klimek, F., Kikuchi, Y., Bannasch, P., and Hino, O. Early detection of Knudson's two-hits in preneoplastic renal cells of the Eker rat model by the laser microdissection procedure. Cancer Res., 55, 989-990 (1995).
    • (1995) Cancer Res. , vol.55 , pp. 989-990
    • Kubo, Y.1    Klimek, F.2    Kikuchi, Y.3    Bannasch, P.4    Hino, O.5
  • 20
    • 0029146454 scopus 로고
    • Allelic loss at the tuberous sclerosis (Tsc2) gene locus in spontaneous uterine leiomyosarcomas and pituitary adenomas in the Eker rat model
    • Kubo, Y., Kikuchi, Y., Mitani, H., Kobayashi, E., Kobayashi, T., and Hino, O. Allelic loss at the tuberous sclerosis (Tsc2) gene locus in spontaneous uterine leiomyosarcomas and pituitary adenomas in the Eker rat model. Jpn. J. Cancer Res., 86, 828-832 (1995).
    • (1995) Jpn. J. Cancer Res. , vol.86 , pp. 828-832
    • Kubo, Y.1    Kikuchi, Y.2    Mitani, H.3    Kobayashi, E.4    Kobayashi, T.5    Hino, O.6
  • 21
    • 0029147142 scopus 로고
    • De novo frame-shift mutation in the tuberin gene
    • Kumar, A., Wolpert, C., Kandt, R. S. De novo frame-shift mutation in the tuberin gene. Hum. Mol. Genet., 4, 1471-1472 (1995).
    • (1995) Hum. Mol. Genet. , vol.4 , pp. 1471-1472
    • Kumar, A.1    Wolpert, C.2    Kandt, R.S.3
  • 22
    • 0030044323 scopus 로고    scopus 로고
    • Suppression of the neoplastic phenotype by replacement of the Tsc2 gene in Eker rat renal carcinoma cells
    • Orimoto, K., Tsuchiya, H., Kobayashi, T., Matsuda, T. and Hino, O. Suppression of the neoplastic phenotype by replacement of the Tsc2 gene in Eker rat renal carcinoma cells. Biochem. Biophys. Res. Commun., 219, 70-75 (1996).
    • (1996) Biochem. Biophys. Res. Commun. , vol.219 , pp. 70-75
    • Orimoto, K.1    Tsuchiya, H.2    Kobayashi, T.3    Matsuda, T.4    Hino, O.5
  • 23
    • 0026768481 scopus 로고
    • Localization of the interference gene cluster to rat chromosome bands 5q31-q33 by fluorescence in situ hybridization
    • Testa, J. R., Taguchi, T., Knudson, A. G., and Hino, O. Localization of the interference gene cluster to rat chromosome bands 5q31-q33 by fluorescence in situ hybridization. Cytogenet. Cell Genet., 60, 247-249 (1992).
    • (1992) Cytogenet. Cell Genet. , vol.60 , pp. 247-249
    • Testa, J.R.1    Taguchi, T.2    Knudson, A.G.3    Hino, O.4
  • 24
    • 0027770784 scopus 로고
    • Identification and characterization of the tuberous sclerosis gene on chromosome 16
    • The European Chromosome 16 Tuberous Sclerosis Consortium. Identification and characterization of the tuberous sclerosis gene on chromosome 16. Cell, 75, 1305-1315 (1993).
    • (1993) Cell , vol.75 , pp. 1305-1315
  • 25
    • 0028073799 scopus 로고
    • Isolation of genes differentially expressed between the Yoshida sarcoma and long-survival Yoshida sarcoma variants: Origin of Yoshida sarcoma revisited
    • Tsuchiya, H., Tsuchiya, Y., Kobayashi, T., Kikuchi, Y. and Hino, O. Isolation of genes differentially expressed between the Yoshida sarcoma and long-survival Yoshida sarcoma variants: origin of Yoshida sarcoma revisited. Jpn. J. Cancer Res., 85, 1099-1104 (1994).
    • (1994) Jpn. J. Cancer Res. , vol.85 , pp. 1099-1104
    • Tsuchiya, H.1    Tsuchiya, Y.2    Kobayashi, T.3    Kikuchi, Y.4    Hino, O.5
  • 26
    • 0030064915 scopus 로고    scopus 로고
    • Presence of potent transcriptional activation domains in the predisposing tuberous sclerosis (Tsc2) gene product of the Eker rat model
    • Tsuchiya, H., Orimoto, K., Kobayashi, T., and Hino. O. Presence of potent transcriptional activation domains in the predisposing tuberous sclerosis (Tsc2) gene product of the Eker rat model. Cancer Res., 56, 429-433 (1996).
    • (1996) Cancer Res. , vol.56 , pp. 429-433
    • Tsuchiya, H.1    Orimoto, K.2    Kobayashi, T.3    Hino, O.4
  • 27
    • 0025781191 scopus 로고
    • Altered expression of transforming growth factor-α in hereditary rat renal cell carcinoma
    • Walker, C., Everitt, J., Freed, J. J., Knudson, A. G., and Whiteley, L. O. Altered expression of transforming growth factor-α in hereditary rat renal cell carcinoma. Cancer Res., 51, 2973-2978 (1991).
    • (1991) Cancer Res. , vol.51 , pp. 2973-2978
    • Walker, C.1    Everitt, J.2    Freed, J.J.3    Knudson, A.G.4    Whiteley, L.O.5
  • 28
    • 0027996238 scopus 로고
    • Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene
    • Yeung, R. C., Xiao, G. H., Jin, F., Lee, W.-C., Testa, J. R. and Knudson, A. G. Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene. Proc. Natl. Acad. Sci. USA, 91, 11413-11416 (1994).
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 11413-11416
    • Yeung, R.C.1    Xiao, G.H.2    Jin, F.3    Lee, W.-C.4    Testa, J.R.5    Knudson, A.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.