The application of equilibrium dialysis to the determination of drug-cyclodextrin stability constants

Journal of Inclusion Phenomena and Molecular Recognition in Chemistry

Volumn 25, Issue 1-3, 1996, Pages 173-176

  Ugwu, Sydney O ^a   Alcala, Marcos J ^a   Bhardwaj, Renu ^a   Blanchard, James ^a  

^a UNIVERSITY OF ARIZONA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0030376666     PISSN: 09230750     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01041563     Document Type: Article

References (7)

1. M.C. Meyer and D.E. Guttman. The binding of drugs by plasma proteins. J. Pharm. Sci., 57:895-918 (1968).
2. K.A. Connors. Binding Constants: The Measurement of Molecular Complex Stability, John Wiley & Sons, New York, NY, 1987, p. 266.
3. E.E. Sideris, M.A. Koupparis and P.E. Macheras. Effect of cyclodextrins on protein binding of drugs: the diflunisal/hydroxypropyl-β-cyclodextrin model case. Pharm. Res. 11:90-95 (1994).
4. M. Vikmon. Rapid and simple spectrophotometric method for determination of micro-amounts of cyclodextrins. 1st Int. Sympos. Cyclodextrins, 1981, Budapest, Hungary, pp. 69-74.
5. G.F. Lockwood and J.G. Wagner. Plasma volume changes as a result of equilibrium dialysis. J. Pharm. Pharmacol. 35:387-399 (1983).
6. G. Scatchard. The attractions of proteins for small molecules and ions. Ann. N.Y. Acad. Sci., 51:660-672 (1949).
7. T.W. Plumbridge, L.J. Aarons and J.R. Broun. Problems associated with analysis and interpretation of small molecule/macromolecule binding data. J. Pharm. Pharmacol. 30:69-74 (1977).