External versus internal metabolic activation of polycyclic aromatic compounds in mutagenicity tests: A comparison using heterologous expression systems

Polycyclic Aromatic Compounds

Volumn 10, Issue 1-4, 1996, Pages 43-50

  Glatt, Hansruedi ^a,b   Bartsch, Ingrid ^b   Doehmer, Johannes ^c   Chneider, Gisela Werle S ^b  

^a GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^b UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

1 hydroxymethylpyrene; 6 hydroxymethyl benzo a pyrene; Benzo a pyrene trans 7,8 dihydrodiol; Cytchrome P450; Intercellular transport of reactive metabolites; Mutagenicity; Sulfotransferase

Indexed keywords

BIOMOLECULES; CELL CULTURE; CHEMICAL ACTIVATION; CHLORINE COMPOUNDS; METABOLISM; METABOLITES; MUTAGENESIS; PYRENE; SALMONELLA;

1-HYDROXYMETHYLPYRENE; 6-HYDROXYMETHYL-BENZO[A]PYRENE; BENZO(A)PYRENE; BENZO[A]PYRENE-TRANS-7,8-DIHYDRODIOL; CYTCHROME P450; INTERCELLULAR TRANSPORT OF REACTIVE METABOLITE; MUTAGENICITY; REACTIVE METABOLITES; SULPHOTRANSFERASE;

CELLS;

EID: 0030363426     PISSN: 10406638     EISSN: None     Source Type: Journal    
DOI: 10.1080/10406639608034678     Document Type: Article

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