Inherited susceptibility and acquired allelic imbalance in rat mammary carcinogenesis

Journal of Cellular Biochemistry

Volumn 63, Issue SUPPL. 25, 1996, Pages 37-40

  Gould, Michael N ^a   Lubet, Ronald A ^b   Kelloff, Gary J ^b   Haag, Jill D ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

cancer genetics; chemoprevention; epigenetic; mammary cancer

Indexed keywords

DIMETHYLBENZ[A]ANTHRACENE; DNA;

ALLELISM; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BREAST CARCINOGENESIS; CANCER SUSCEPTIBILITY; CHEMOPROPHYLAXIS; CHROMOSOME 1; FEMALE; GENETIC SUSCEPTIBILITY; HETEROZYGOSITY LOSS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; ALLELE; ANIMAL; DISEASE MODEL; DISEASE PREDISPOSITION; EXPERIMENTAL NEOPLASM; GENETICS; REVIEW;

ANIMALIA;

ALLELES; ANIMALS; DISEASE MODELS, ANIMAL; DISEASE SUSCEPTIBILITY; FEMALE; MAMMARY NEOPLASMS, EXPERIMENTAL; RATS;

EID: 0030345808     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1097-4644(1996)25+<37::aid-jcb5>3.0.co;2-3     Document Type: Article

References (11)

1. Gould MN, Wang B, Moore CJ (1989): Modulation of mammary carcinogenesis by enhancer and suppressor genes. In Colburn NH (ed): "Genes and Signal Transduction in Multistage Carcinogenesis." New York: Marcel Dekker, Inc., pp 19-38.
2. Wiklund J, Rutledge J, Gorski J (1981): A genetic model for the inheritance of pituitary tumor susceptibility in F344 rats. Encorinology 109:1708-1714.
3. Gould MN (1986): Inheritance and site of expression of genes controlling susceptibility to mammary cancer in an inbred rat model. Cancer Res 46:1199-1202.
4. Zhang R, Haag JD, Gould MN (1990): Site of expression and biological function of the rat mammary carcinoma suppressor gene. Carcinogenesis 11:1765-1770.
5. Hsu LC, Kennan WS, Shepel LA, Jacob HJ, Szpirer C, Szpirer J, Lander ES, Gould MN (1994): Genetic identification of Mcs-1, a rat mammary carcinoma suppressor gene. Cancer Res 54:2765-2770.
6. Hsu LC, Gould MN (1993): Cloning and characterization of overexpressed genes in the mammary gland of rat strains carrying the mammary carcinoma suppressor (Mes) gene. Cancer Res 53:5766-5774.
7. Cho KR, Vogelstein B (1992): Genetic alterations in the adenoma-carcinoma sequence. Cancer 70:1727-1731.
8. Gould MN (1993): Cellular and molecular aspects of the multistage progression of mammary carcinogenesis in humans and rats. Sem Cancer Biol 4:161-169.
9. Jacob HJ, Brown DM, Bunker RK, Daly MJ, Dzau VJ, Goodman A, Koike G, Kren V, Kurtz T, Lernmark A, et al. (1995):A genetic linkage map of the laboratory rat, Rattus norvegicus. Nat Genet 9:63-69.
10. Haag JD, Newton MA, Gould MN (1992): Mammary carcinoma suppressor and susceptibility genes in the Wistar-Kyoto rat. Carcinogenesis 13:1933-1935.
11. Kamiya K, Yasukawa-Barnes J, Mitchen JM, Gould MN, Clifton KH (1995): Evidence that carcinogenesis involves an imbalance between epigenetic high-frequency initiation and suppression of promotion. Proc Natl Acad Sci U S A 92:1332-1336.